933d7d7ba7b25ae1c658b7f01ea37078 pmc_34083035.pdf 8f7a9e1f8bdd0105b4d99d24e036cb5dff10b298 pmc_34083035.pdf aeedfdc050bd384f8de486f77808a633847b9cb6288cd526f00a4f5269fd4a60 pmc_34083035.pdf Title: The hCOMET project: International database comparison of results with the comet assay in human biomonitoring. Baseline frequency of DNA damage and effect of main confounders Keywords: Comet assay, DNA damage, Pooled analysis, Human biomonitoring, Biomarkers Author: Mirta Milić, Marcello Ceppi, Marco Bruzzone, Amaya Azqueta, Gunnar Brunborg, Roger Godschalk, Gudrun Koppen, Sabine Langie, Peter Møller, João Paulo Teixeira, Avdulla Alija, Diana Anderson, Vanessa Andrade, Cristina Andreoli, Fisnik Asllani, Ezgi Eyluel Bangkoglu, Magdalena Barančoková, Nursen Basaran, Elisa Boutet-Robinet, Annamaria Buschini, Delia Cavallo, Cristiana Costa Pereira, Carla Costa, Solange Costa, Juliana Da Silva, Cristian Del Bó, Vesna Dimitrijević Srećković, Ninoslav Djelić, Malgorzata Dobrzyńska, Zdenka Duračková, Monika Dvořáková, Goran Gajski, Serena Galati, Omar García Lima, Lisa Giovannelli, Irina A. Goroshinskaya, Annemarie Grindel, Kristine B. Gutzkow, Alba Hernández, Carlos Hernández, Kirsten B. Holven, Idoia Ibero-Baraibar, Inger Ottestad, Ela Kadioglu, Alena Kažimirová, Elena Kuznetsova, Carina Ladeira, Blanca Laffon, Palma Lamonaca, Pierre Lebailly, Henriqueta Louro, Tania Mandina Cardoso, Francesca Marcon, Ricard Marcos, Massimo Moretti, Silvia Moretti, Mojgan Najafzadeh, Zsuzsanna Nemeth, Monica Neri, Bozena Novotna, Irene Orlow, Zuzana Paduchova, Susana Pastor, Hervé Perdry, Biljana Spremo-Potparević, Dwi Ramadhani, Patrizia Riso, Paula Rohr, Emilio Rojas, Pavel Rossner, Anna Safar, Semra Sardas, Maria João Silva, Nikolay Sirota, Bozena Smolkova, Marta Staruchova, Rudolf Stetina, Helga Stopper, Ekaterina I. Surikova, Stine M. Ulven, Cinzia Lucia Ursini, Vanessa Valdiglesias, Mahara Valverde, Pavel Vodicka, Katarina Volkovova, Karl-Heinz Wagner, Lada Živković, Maria Dušinská, Andrew R. Collins, Stefano Bonassi Creator: AH Formatter V7.1 MR2 for Linux64 : 7.1.3.50324 (2021-04-26T09:47+09) Producer: Antenna House PDF Output Library 7.1.1639 CreationDate: Tue Oct 19 22:33:42 2021 CEST ModDate: Tue Oct 19 22:33:42 2021 CEST Tagged: yes UserProperties: no Suspects: no Form: none JavaScript: no Pages: 28 Encrypted: no Page size: 612 x 792 pts (letter) Page rot: 0 File size: 1212220 bytes Optimized: no PDF version: 1.5 name type encoding emb sub uni object ID ------------------------------------ ----------------- ---------------- --- --- --- --------- Helvetica-Bold Type 1 Standard no no no 11 0 Helvetica-BoldOblique Type 1 Standard no no no 12 0 Helvetica-Oblique Type 1 Standard no no no 14 0 Times-Roman Type 1 Custom no no yes 18 0 Helvetica Type 1 Custom no no yes 23 0 OOMFBR+Code2000 CID TrueType Identity-H yes yes yes 119 0 Times-Bold Type 1 Custom no no yes 572 0 Times-BoldItalic Type 1 Custom no no yes 653 0 Jhove (Rel. 1.22.1, 2019-04-17) Date: 2023-05-27 02:43:58 CEST RepresentationInformation: pmc_34083035.pdf ReportingModule: PDF-hul, Rel. 1.12.1 (2019-04-17) LastModified: 2023-03-31 12:14:06 CEST Size: 1212220 Format: PDF Version: 1.5 Status: Well-Formed and valid SignatureMatches: PDF-hul MIMEtype: application/pdf PDFMetadata: Objects: 0 FreeObjects: 713 IncrementalUpdates: 0 DocumentCatalog: ViewerPreferences: HideToolbar: false HideMenubar: false HideWindowUI: false FitWindow: false CenterWindow: false DisplayDocTitle: false NonFullScreenPageMode: UseNone Direction: L2R ViewArea: CropBox ViewClip: CropBox PrintArea: CropBox PageClip: CropBox PageLayout: SinglePage PageMode: UseOutlines Language: EN Outlines: Item: Title: Abstract Item: Title: Introduction Item: Title: Materials and methods Children: Item: Title: The hCOMET database Item: Title: Laboratory methods Item: Title: Statistical analysis Item: Title: Results Children: Item: Title: Background frequency of DNA damage Item: Title: Distribution of DNA damage by age and sex Item: Title: Other major confounding factors Item: Title: Discussion Item: Title: Conclusions Item: Title: References Item: Title: Fig. 1. Item: Title: Fig. 2. Item: Title: Fig. 3. Item: Title: Fig. 4. Item: Title: Table 1 Item: Title: Table 2 Item: Title: Table 3 Filters: FilterPipeline: FlateDecode FilterPipeline: DCTDecode Images: Image: NisoImageMetadata: FormatName: image/jpg CompressionScheme: JPEG ImageWidth: 152 ImageHeight: 152 ColorSpace: RGB BitsPerSample: 8 BitsPerSampleUnit: integer Image: NisoImageMetadata: FormatName: image/jpg CompressionScheme: JPEG ImageWidth: 1800 ImageHeight: 930 BitsPerSample: 8 BitsPerSampleUnit: integer Image: NisoImageMetadata: FormatName: image/jpg CompressionScheme: JPEG ImageWidth: 1800 ImageHeight: 1214 BitsPerSample: 8 BitsPerSampleUnit: integer Image: NisoImageMetadata: FormatName: image/jpg CompressionScheme: JPEG ImageWidth: 1240 ImageHeight: 1800 BitsPerSample: 8 BitsPerSampleUnit: integer Image: NisoImageMetadata: FormatName: image/jpg CompressionScheme: JPEG ImageWidth: 1371 ImageHeight: 1800 BitsPerSample: 8 BitsPerSampleUnit: integer Fonts: Type0: Font: BaseFont: OOMFBR+Code2000 Encoding: Identity-H ToUnicode: true Type1: Font: BaseFont: Times-Roman FirstChar: 32 LastChar: 148 FontDescriptor: FontName: Times-Roman Flags: Nonsymbolic FontBBox: -168, -218, 1000, 898 EncodingDictionary: Differences: true ToUnicode: true Font: BaseFont: Helvetica FirstChar: 32 LastChar: 150 FontDescriptor: FontName: Helvetica Flags: Nonsymbolic FontBBox: -166, -225, 1000, 931 EncodingDictionary: Differences: true ToUnicode: true Font: BaseFont: Helvetica-Bold Font: BaseFont: Helvetica-BoldOblique Font: BaseFont: Times-Bold FirstChar: 32 LastChar: 129 FontDescriptor: FontName: Times-Bold Flags: Nonsymbolic FontBBox: -168, -218, 1000, 935 EncodingDictionary: Differences: true ToUnicode: true Font: BaseFont: Times-BoldItalic FirstChar: 32 LastChar: 129 FontDescriptor: FontName: Times-BoldItalic Flags: Nonsymbolic, Italic FontBBox: -200, -218, 996, 921 EncodingDictionary: Differences: true ToUnicode: true Font: BaseFont: Helvetica-Oblique CIDFontType2: Font: BaseFont: OOMFBR+Code2000 CIDSystemInfo: Registry: Adobe Registry: Identity Supplement: 0 FontDescriptor: FontName: OOMFBR+Code2000 Flags: Symbolic FontBBox: -1111, -295, 2107, 977 FontFile2: true XMP: 2021-10-19T15:33:42-05:00 2021-10-19T15:33:42-05:00 application/pdf Antenna House PDF Output Library 7.1.1639 Comet assay, DNA damage, Pooled analysis, Human biomonitoring, Biomarkers AH Formatter V7.1 MR2 for Linux64 : 7.1.3.50324 (2021-04-26T09:47+09) 2021-10-19T15:33:42-05:00 The hCOMET project: International database comparison of results with the comet assay in human biomonitoring. Baseline frequency of DNA damage and effect of main confounders Mirta Milić, Marcello Ceppi, Marco Bruzzone, Amaya Azqueta, Gunnar Brunborg, Roger Godschalk, Gudrun Koppen, Sabine Langie, Peter Møller, João Paulo Teixeira, Avdulla Alija, Diana Anderson, Vanessa Andrade, Cristina Andreoli, Fisnik Asllani, Ezgi Eyluel Bangkoglu, Magdalena Barančoková, Nursen Basaran, Elisa Boutet-Robinet, Annamaria Buschini, Delia Cavallo, Cristiana Costa Pereira, Carla Costa, Solange Costa, Juliana Da Silva, Cristian Del Bó, Vesna Dimitrijević Srećković, Ninoslav Djelić, Malgorzata Dobrzyńska, Zdenka Duračková, Monika Dvořáková, Goran Gajski, Serena Galati, Omar García Lima, Lisa Giovannelli, Irina A. Goroshinskaya, Annemarie Grindel, Kristine B. Gutzkow, Alba Hernández, Carlos Hernández, Kirsten B. Holven, Idoia Ibero-Baraibar, Inger Ottestad, Ela Kadioglu, Alena Kažimirová, Elena Kuznetsova, Carina Ladeira, Blanca Laffon, Palma Lamonaca, Pierre Lebailly, Henriqueta Louro, Tania Mandina Cardoso, Francesca Marcon, Ricard Marcos, Massimo Moretti, Silvia Moretti, Mojgan Najafzadeh, Zsuzsanna Nemeth, Monica Neri, Bozena Novotna, Irene Orlow, Zuzana Paduchova, Susana Pastor, Hervé Perdry, Biljana Spremo-Potparević, Dwi Ramadhani, Patrizia Riso, Paula Rohr, Emilio Rojas, Pavel Rossner, Anna Safar, Semra Sardas, Maria João Silva, Nikolay Sirota, Bozena Smolkova, Marta Staruchova, Rudolf Stetina, Helga Stopper, Ekaterina I. Surikova, Stine M. Ulven, Cinzia Lucia Ursini, Vanessa Valdiglesias, Mahara Valverde, Pavel Vodicka, Katarina Volkovova, Karl-Heinz Wagner, Lada Živković, Maria Dušinská, Andrew R. Collins, Stefano Bonassi Pages: Page: Sequence: 1 Annotations: Annotation: Subtype: Link Contents: https://doi.org/10.1016/j.mrrev.2021.108371 Rect: 371, 72, 513, 80 LastModified: D:20211019153342-05'00' Page: Sequence: 2 Page: Sequence: 3 Page: Sequence: 4 Page: Sequence: 5 Page: Sequence: 6 Page: Sequence: 7 Page: Sequence: 8 Page: Sequence: 9 Page: Sequence: 10 Page: Sequence: 11 Page: Sequence: 12 Page: Sequence: 13 Page: Sequence: 14 Page: Sequence: 15 Page: Sequence: 16 Annotations: Annotation: Subtype: Link Contents: www.cost.eu Rect: 279, 487, 321, 495 LastModified: D:20211019153342-05'00' Annotation: Subtype: Link Contents: ClinicalTrials.org Rect: 358, 306, 414, 314 LastModified: D:20211019153342-05'00' Annotation: Subtype: Link Contents: NCT02231736 Rect: 423, 306, 471, 314 LastModified: D:20211019153342-05'00' Page: Sequence: 17 Page: Sequence: 18 Page: Sequence: 19 Page: Sequence: 20 Page: Sequence: 21 Page: Sequence: 22 Page: Sequence: 23 Page: Sequence: 24 Page: Sequence: 25 Page: Sequence: 26 Page: Sequence: 27 Page: Sequence: 28 Checksum: e59b72d0 Type: CRC32 Checksum: 933d7d7ba7b25ae1c658b7f01ea37078 Type: MD5 Checksum: 8f7a9e1f8bdd0105b4d99d24e036cb5dff10b298 Type: SHA-1