e2d0e6ea737780557618532ccd01ace9 pmc_34177915.pdf c21ad1e02a39305c685ec929400aee1a85963ea7 pmc_34177915.pdf 645a312a166cd1e98945fb40e052482b241adf757d6b2234565291c37b6cd350 pmc_34177915.pdf Title: Interaction of Type 1 Porcine Reproductive and Respiratory Syndrome Virus With In Vitro Derived Conventional Dendritic Cells Subject: The present study delineates the interaction of a typical PRRSV1 Keywords: PRRSV1, conventional dendritic cells, TLR3, TLR7, innate immune response Author: Yanli Li Creator: Arbortext Advanced Print Publisher 10.0.1306/W Unicode Producer: Acrobat Distiller 7.0 (Windows) CreationDate: Wed Jun 9 09:36:13 2021 CEST ModDate: Wed Jun 9 13:26:57 2021 CEST Custom Metadata: no Metadata Stream: yes Tagged: no UserProperties: no Suspects: no Form: none JavaScript: no Pages: 15 Encrypted: no Page size: 595.276 x 779.528 pts Page rot: 0 File size: 16960808 bytes Optimized: no PDF version: 1.4 name type encoding emb sub uni object ID ------------------------------------ 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Invalid indirect destination - referenced object 'SF2' cannot be found ID: PDF-HUL-122 Offset: 16935057 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'SF1' cannot be found ID: PDF-HUL-122 Offset: 16935057 MIMEtype: application/pdf PDFMetadata: Objects: 778 FreeObjects: 1 IncrementalUpdates: 2 DocumentCatalog: PageLayout: SinglePage PageMode: UseOutlines Outlines: Item: Title: Interaction of Type 1 Porcine Reproductive and Respiratory Syndrome Virus With In Vitro Derived Conventional Dendritic Cells Destination: bmark_571246712 Children: Item: Title: Introduction Destination: s1 Item: Title: Materials and Methods Destination: s2 Children: Item: Title: Obtention of Bone Marrow Hematopoietic Cells and Alveolar Macrophages, and Isolation of Peripheral Blood Mononuclear Cells Destination: s2_1 Item: Title: Virus Production and Titration Destination: s2_2 Item: Title: Generation and Sorting of DCs Destination: s2_3 Item: Title: PRRSV Infection Destination: s2_4 Item: Title: Stimulation of cDC1, cDC2, and CD14+ DCs Destination: s2_5 Item: Title: Co-Culture of cDC1, cDC2, and CD14+ DCs With Infected MARC-145 Cells Destination: s2_6 Item: Title: Mixed Lymphocyte Reaction Assay Destination: s2_7 Item: Title: Endocytosis/Phagocytosis Assay Destination: s2_8 Item: Title: Detection of Cytokines/Chemokines Destination: s2_9 Item: Title: Statistical Analysis Destination: s2_10 Item: Title: Results Destination: s3 Children: Item: Title: cDC1 and cDC2 Were Not Susceptible to PRRSV1 Infection, a Fraction of CD14+ DCs Were Infected Destination: s3_1 Item: Title: Exposure of CDC1, CDC2, and CD14+ DCs to PRRSV1 3267 Suspensions Did Not Change the Expression of MHC-I, MHC-II, CD80/86, or CCR7, Did Not Induce any Significant Cytokine Release, Did Not Modify T-Cell Proliferation in the MLR, and Did Not Affect the End漀挀礀琀椀挀⼀倀栀愀最漀挀礀琀椀挀 䌀愀瀀愀戀椀氀椀琀椀攀猩㸾൥湤潢樍ㄠ〠潢樼㰯䍲潰䉯硛〠〠㔹㔮㈷㘠㜷㤮㔲㡝⽁湮潴獛㈠〠删㌠〠删㐠〠删㔠〠删㘠〠删㜠〠删㠠〠删㤠〠删㄰‰⁒‱ㄠ〠删ㄲ‰⁒‱㌠〠删ㄴ‰⁒‱㔠〠删ㄶ‰⁒‱㜠〠删ㄸ‰⁒‱㤠〠删㈰‰⁒′ㄠ〠剝⽐慲敮琠㐹㠠〠刯䉛㔲㜠〠删㘹㔠〠删㘹㐠〠删㘹㌠〠删㘹㈠〠删㘹ㄠ〠剝⽃潮瑥湴猠㈳‰⁒⽒潴慴攠〯䵥摩慂潸嬰‰‵㤵⸲㜶‷㜹⸵㈸崯剥獯畲捥猠㈲‰⁒⽔祰支偡来㸾൥湤潢樍㈠〠潢樼㰯剥捴嬲㌰⸹ㄠ㐹㐮㜵㤠㈳㔮㐴㘠㔰㐮㈸㍝⽓畢瑹灥⽌楮欯䉯牤敲嬰‰‰崯䑥獴⣾＀䈀ㄩ⽔祰支䅮湯琾㸍敮摯扪ള‰扪㰼⽒散瑛㈴〮㌲ㄠ㐹㐮㜵㤠㈴㐮㠵㜠㔰㐮㈸㍝⽓畢瑹灥⽌楮欯䉯牤敲嬰‰‰崯䑥獴⣾＀䈀㐩⽔祰支䅮湯琾㸍敮摯扪ഴ‰扪㰼⽒散瑛㈳㤮〷㐠㐴㠮㜸ㄠ㈴㌮㘰㤠㐵㠮㈴㥝⽓畢瑹灥⽌楮欯䉯牤敲嬰‰‰崯䑥獴⣾＀䈀㔩⽔祰支䅮湯琾㸍敮摯扪വ‰扪㰼⽒散瑛㠷⸱㌷‴〲⸷㐶‹ㄮ㜲㤠㐱㈮㈷ㅝ⽓畢瑹灥⽌楮欯䉯牤敲嬰‰‰崯䑥獴⣾＀䈀㘩⽔祰支䅮湯琾㸍敮摯扪ശ‰扪㰼⽒散瑛㤶⸶〵‴〲⸷㐶‱〱⸱㐠㐱㈮㈷ㅝ⽓畢瑹灥⽌楮欯䉯牤敲嬰‰‰崯䑥獴⣾＀䈀㠩⽔祰支䅮湯琾㸍敮摯扪ഷ‰扪㰼⽒散瑛㈳㜮㘠㌹ㄮ㈳㠠㈴㈮ㄳ㔠㐰〮㜶㉝⽓畢瑹灥⽌楮欯䉯牤敲嬰‰‰崯䑥獴⣾＀䈀㤩⽔祰支䅮湯琾㸍敮摯扪സ‰扪㰼⽒散瑛㤰⸷〹″㘸⸲㜷‹㤮㠳㘠㌷㜮㜴㕝⽓畢瑹灥⽌楮欯䉯牤敲嬰‰‰崯䑥獴⣾＀䈀㄀〩⽔祰支䅮湯琾㸍敮摯扪ഹ‰扪㰼⽒散瑛㄰ㄮ㌱″㄰⸷㤠ㄱ〮㌸ㄠ㌲〮㈵㡝⽓畢瑹灥⽌楮欯䉯牤敲嬰‰‰崯䑥獴⣾＀䈀㄀ㄩ⽔祰支䅮湯琾㸍敮摯扪റ〠〠潢樼㰯剥捴嬱ㄵ⸲㔷″㄰⸷㤠ㄲ㐮㌲㠠㌲〮㈵㡝⽓畢瑹灥⽌楮欯䉯牤敲嬰‰‰崯䑥獴⣾＀䈀㄀㌩⽔祰支䅮湯琾㸍敮摯扪റㄠ〠潢樼㰯剥捴嬴㠮㘴㌠㈱㠮㜷㠠㔷⸷ㄳ′㈸⸲㐶崯卵扴祰支䱩湫⽂潲摥牛〠〠そ⽄敳琨B14 Destination: s3_2 Item: Title: Pre-Exposure of cDC2 or CD14+ DCs, but Not cDC1 to PRRSV1 3267 Suspensions Enhanced Proliferation of CD4+CD25+Foxp3+ Regulatory T Cells (Tregs) Destination: s3_3 Item: Title: PRRSV1 Modified the Response of cDC2 and CD14+ DCs to Poly I:C and Gardiquimod Stimulation Destination: s3_4 Item: Title: cDC2 and CD14+ DCs, but Not cDC1 Efficiently Sensed 3267-Infected Cells Destination: s3_5 Item: Title: Discussion Destination: s4 Item: Title: Data Availability Statement Destination: s5 Item: Title: Ethics Statement Destination: s6 Item: Title: Author Contributions Destination: s7 Item: Title: Funding Destination: s8 Item: Title: Acknowledgments Destination: bmark_-366698314 Item: Title: Supplementary Material Destination: bmark_386646472 Item: Title: References Destination: bmark_2090415954 Info: Title: Interaction of Type 1 Porcine Reproductive and Respiratory Syndrome Virus With In Vitro Derived Conventional Dendritic Cells Author: Yanli Li Subject: The present study delineates the interaction of a typical PRRSV1 Keywords: PRRSV1, conventional dendritic cells, TLR3, TLR7, innate immune response Creator: Arbortext Advanced Print Publisher 10.0.1306/W Unicode Producer: Acrobat Distiller 7.0 (Windows) CreationDate: Wed Jun 09 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ToUnicode: true XMP: Acrobat Distiller 7.0 (Windows) PRRSV1, conventional dendritic cells, TLR3, TLR7, innate immune response 2021-06-09T15:36:13+08:00 2021-06-09T19:26:57+08:00 Arbortext Advanced Print Publisher 10.0.1306/W Unicode 2021-06-09T19:26:57+08:00 application/pdf Yanli Li Enric Mateu The present study delineates the interaction of a typical PRRSV1 Interaction of Type 1 Porcine Reproductive and Respiratory Syndrome Virus With In Vitro Derived Conventional Dendritic Cells PRRSV1 conventional dendritic cells TLR3 TLR7 innate immune response uuid:8c91482d-6ac6-4c65-9c82-6b18d266724d uuid:dafb2c67-ac0c-4720-a6e2-74d0ff347d43 Pages: Page: Label: 1 Annotations: Annotation: Subtype: Link Rect: 175, 577, 463, 598 Annotation: Subtype: Link Rect: 175, 554, 473, 575 Annotation: Subtype: Link Rect: 175, 531, 543, 552 Annotation: Subtype: Link Rect: 175, 508, 458, 529 Annotation: Subtype: Link Rect: 45, 29, 116, 36 Annotation: Subtype: Link Rect: 125, 29, 183, 36 Annotation: Subtype: Link 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