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Title:          Cord blood and amniotic membrane extract eye drop preparations display immune-suppressive and regenerative properties
Subject:        Scientific Reports, https://doi.org/10.1038/s41598-021-93150-7
Author:         Dinara Samarkanova 
Creator:        Springer
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     Item: 
      Title: Cord blood and amniotic membrane extract eye drop preparations display immune-suppressive and regenerative properties
      Children: 
       Item: 
        Title: Results
        Children: 
         Item: 
          Title: CBED and AMED are rich in growth factors and cytokines. 
         Item: 
          Title: Neither CBED or AMED were cytotoxic and both improved in vitro cell growth. 
         Item: 
          Title: CBED and AMED support cell migration and close the scratched area in an in vitro wound healing assay. 
         Item: 
          Title: Growth factors present in the eye drop preparations are able to penetrate the corneal tissue. 
         Item: 
          Title: CBED and AMED have an immunosuppressive effect on activated lymphocytes. 
          Children: 
           Item: 
            Title: Both eye-drop preparations improve peripheral blood mononuclear cell (PBMC) viability. 
           Item: 
            Title: Incubation with CBED and AMED reduces expression of NKG2D. 
           Item: 
            Title: Incubation with CBED and AMED reduces expression of CD107a and IFN-γ. 
           Item: 
            Title: CBED but not AMED contains sNKG2DLs. 
       Item: 
        Title: Discussion
       Item: 
        Title: Materials and methods
        Children: 
         Item: 
          Title: Study description and research ethics. 
         Item: 
          Title: Subjects and sample preparation. 
          Children: 
           Item: 
            Title: Preparation of CBED. 
           Item: 
            Title: Preparation of AMED. 
         Item: 
          Title: Growth factor and cytokine assessment. 
         Item: 
          Title: Cytotoxicity assay. 
         Item: 
          Title: Cellular growth assay. 
         Item: 
          Title: In vitro wound healing assay. 
         Item: 
          Title: Ex vivo corneal bioavailability assay. 
         Item: 
          Title: In vitro immune modulation assay. 
         Item: 
          Title: Statistical analysis. 
       Item: 
        Title: References
       Item: 
        Title: Acknowledgements
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AM = Accepted Manuscript
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