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Keywords: stroke, angiogenin, neural stem/progenitor cells, neurogenesis, neurorepair, exercise Author: Anna Rosell Creator: LaTeX with hyperref package + hypdvips Producer: dvips + MiKTeX GPL Ghostscript 9.0 CreationDate: Tue Jun 15 10:13:11 2021 CEST ModDate: Tue Jun 15 10:20:12 2021 CEST Custom Metadata: no Metadata Stream: yes Tagged: no UserProperties: no Suspects: no Form: none JavaScript: no Pages: 10 Encrypted: no Page size: 595.26 x 779.52 pts Page rot: 0 File size: 1624753 bytes Optimized: no PDF version: 1.6 name type encoding emb sub uni object ID ------------------------------------ ----------------- ---------------- --- --- --- --------- HWWDDU+HelveticaNeueLTStd-Bd Type 1C WinAnsi yes yes no 37 0 ROVICS+HelveticaNeueLTStd-Lt Type 1C Custom yes yes no 42 0 PIAOFJ+HelveticaNeueLTStd-BdIt Type 1C WinAnsi yes yes no 55 0 CSPZYR+HelveticaNeueLTStd-LtIt Type 1C Custom yes yes no 57 0 CNZDTB+HelveticaNeueLTStd-MdIt Type 1C WinAnsi yes yes no 62 0 OOAPJM+MTSY Type 1C Custom yes yes yes 64 0 KSMOFD+MinionPro-Regular Type 1C Custom yes yes no 66 0 XFKDJC+MinionPro-It Type 1C Custom yes yes no 93 0 YODSOG+MTGU Type 1C Custom yes yes no 106 0 OBAZBH+RMTMI Type 1C WinAnsi yes yes no 108 0 FAVDVV+MinionPro-Bold Type 1C Custom yes yes no 112 0 Jhove (Rel. 1.28.0, 2023-05-18) Date: 2024-10-02 03:11:35 CEST RepresentationInformation: pmc_34234733.pdf ReportingModule: PDF-hul, Rel. 1.12.4 (2023-03-16) LastModified: 2023-03-31 12:14:27 CEST Size: 1624753 Format: PDF Version: 1.6 Status: Well-Formed and valid SignatureMatches: PDF-hul MIMEtype: application/pdf PDFMetadata: Objects: 309 FreeObjects: 15 IncrementalUpdates: 0 DocumentCatalog: ViewerPreferences: HideToolbar: false HideMenubar: false HideWindowUI: false FitWindow: true CenterWindow: false DisplayDocTitle: false NonFullScreenPageMode: UseNone Direction: L2R ViewArea: CropBox ViewClip: CropBox PrintArea: CropBox PageClip: CropBox PageLayout: SinglePage PageMode: UseOutlines Language: en Outlines: Item: Title: Angiogenin in the Neurogenic Subventricular Zone After Stroke Destination: ariclecounter.1 Children: Item: Title: Introduction Destination: section*.2 Item: Title: Materials and Methods Destination: section*.3 Children: Item: Title: Brain Tissue Samples Destination: section*.4 Item: Title: Mouse Habituation and Permanent Focal Cerebral Ischemia Model Destination: section*.5 Item: Title: Pre-clinical Treadmill Rehabilitation Destination: section*.6 Item: Title: Infarct Volume Assessment Destination: section*.7 Item: Title: Angiogenin ELISA Destination: section*.8 Item: Title: Immunohistochemistry Destination: section*.9 Item: Title: Neural Stem Cells Destination: section*.10 Item: Title: NSC Counts and Neurosphere Growth Destination: section*.11 Item: Title: SH-SY5Y Culture and Neurite Outgrowth Destination: section*.12 Item: Title: Western Blot Destination: section*.13 Item: Title: Statistical Analysis Destination: section*.14 Item: Title: Results Destination: section*.15 Children: Item: Title: Angiogenin Is Expressed in the SVZ Neurogenic Niche and Increases NSCs Yields in Free-Floating Neurosphere Destination: section*.16 Item: Title: Physical Exercise Increases SVZ Angiogenin After Ischemia in Areas of Active Neurogenesis Destination: section*.17 Item: Title: Discussion Destination: section*.18 Item: Title: Data Availability Statement Destination: section*.19 Item: Title: Ethics Statement Destination: section*.20 Item: Title: Author Contributions Destination: section*.21 Item: Title: Funding Destination: section*.22 Item: Title: Acknowledgments Destination: section*.23 Item: Title: Supplementary Material Destination: section*.24 Item: Title: References Destination: section*.25 Info: Title: Angiogenin in the Neurogenic Subventricular Zone After Stroke Author: Anna Rosell Subject: Ischemic stroke is a leading cause of death and disability worldwide with effective acute thrombolytic treatments. Keywords: stroke, angiogenin, neural stem/progenitor cells, neurogenesis, neurorepair, exercise Creator: LaTeX with hyperref package + hypdvips Producer: dvips + MiKTeX GPL Ghostscript 9.0 CreationDate: Tue Jun 15 10:43:11 CEST 2021 ModDate: Tue Jun 15 10:50:12 CEST 2021 ID: 0x2d51e0cfb7d37c0b8cc2d180d33313b6, 0xf25a4add1a0e9040bac2a02bb9b24823 Filters: FilterPipeline: FlateDecode FilterPipeline: DCTDecode Images: Image: NisoImageMetadata: FormatName: image/png ImageWidth: 279 ImageHeight: 279 ColorSpace: RGB BitsPerSample: 8 BitsPerSampleUnit: integer Filter: FlateDecode Image: NisoImageMetadata: FormatName: image/jpg CompressionScheme: JPEG ImageWidth: 2008 ImageHeight: 377 ColorSpace: RGB BitsPerSample: 8 BitsPerSampleUnit: integer Interpolate: true Image: NisoImageMetadata: FormatName: image/jpg CompressionScheme: JPEG ImageWidth: 2008 ImageHeight: 1079 ColorSpace: RGB BitsPerSample: 8 BitsPerSampleUnit: integer Interpolate: true Image: NisoImageMetadata: FormatName: image/jpg CompressionScheme: JPEG ImageWidth: 1890 ImageHeight: 1388 ColorSpace: RGB BitsPerSample: 8 BitsPerSampleUnit: integer Interpolate: true Image: NisoImageMetadata: FormatName: image/jpg CompressionScheme: JPEG ImageWidth: 2008 ImageHeight: 1579 ColorSpace: RGB BitsPerSample: 8 BitsPerSampleUnit: integer Interpolate: true Fonts: Type1: Font: BaseFont: OOAPJM+MTSY FontSubset: true FirstChar: 0 LastChar: 68 FontDescriptor: FontName: OOAPJM+MTSY Flags: Symbolic FontBBox: 0, -209, 944, 679 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true ToUnicode: true Font: BaseFont: FAVDVV+MinionPro-Bold FontSubset: true FirstChar: 3 LastChar: 121 FontDescriptor: FontName: FAVDVV+MinionPro-Bold Flags: Symbolic FontBBox: -7, -245, 823, 703 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true Font: BaseFont: KSMOFD+MinionPro-Regular FontSubset: true FirstChar: 2 LastChar: 252 FontDescriptor: FontName: KSMOFD+MinionPro-Regular Flags: Symbolic FontBBox: -26, -257, 956, 713 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true Font: BaseFont: HWWDDU+HelveticaNeueLTStd-Bd FontSubset: true FirstChar: 40 LastChar: 124 FontDescriptor: FontName: HWWDDU+HelveticaNeueLTStd-Bd Flags: Nonsymbolic FontBBox: -9, -214, 848, 786 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: PIAOFJ+HelveticaNeueLTStd-BdIt FontSubset: true FirstChar: 42 LastChar: 121 FontDescriptor: FontName: PIAOFJ+HelveticaNeueLTStd-BdIt Flags: Nonsymbolic FontBBox: -63, -182, 717, 731 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: CSPZYR+HelveticaNeueLTStd-LtIt FontSubset: true FirstChar: 0 LastChar: 250 FontDescriptor: FontName: CSPZYR+HelveticaNeueLTStd-LtIt Flags: Symbolic FontBBox: -137, -206, 978, 729 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true Font: BaseFont: ROVICS+HelveticaNeueLTStd-Lt FontSubset: true FirstChar: 0 LastChar: 239 FontDescriptor: FontName: ROVICS+HelveticaNeueLTStd-Lt Flags: Symbolic FontBBox: -30, -214, 904, 786 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true Font: BaseFont: YODSOG+MTGU FontSubset: true FirstChar: 97 LastChar: 109 FontDescriptor: FontName: YODSOG+MTGU Flags: Symbolic FontBBox: 0, -196, 607, 683 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true Font: BaseFont: OBAZBH+RMTMI FontSubset: true FirstChar: 60 LastChar: 62 FontDescriptor: FontName: OBAZBH+RMTMI Flags: Nonsymbolic, AllCap FontBBox: 0, 0, 683, 455 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: XFKDJC+MinionPro-It FontSubset: true FirstChar: 19 LastChar: 233 FontDescriptor: FontName: XFKDJC+MinionPro-It Flags: Symbolic FontBBox: -142, -257, 903, 712 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true Font: BaseFont: CNZDTB+HelveticaNeueLTStd-MdIt FontSubset: true FirstChar: 42 LastChar: 233 FontDescriptor: FontName: CNZDTB+HelveticaNeueLTStd-MdIt Flags: Symbolic FontBBox: -64, -205, 891, 731 FontFile3: true Encoding: WinAnsiEncoding XMP: 2021-06-15T13:43:11+05:30 LaTeX with hyperref package + hypdvips 2021-06-15T13:50:12+05:30 2021-06-15T13:50:12+05:30 application/pdf Ischemic stroke is a leading cause of death and disability worldwide with effective acute thrombolytic treatments. 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