b3b4eadaca20419086bc7820a049974e pmc_34277643.pdf d422900e3e5d721b9a3026dffb0ea73663300cfa pmc_34277643.pdf 98871b3a0733bf64bbc96963f3b88ee8f7f87816a8e4f1184f376dbf9d80863b pmc_34277643.pdf Title: Modular Evolution and Population Variability of Oikopleura dioica Metallothioneins Subject: Chordate Oikopleura dioica probably is the fastest evolving metazoan reported so far, and thereby, a suitable system in which to explore the limits of evolutionary processes. Keywords: appendicularian tunicate chordates, modular protein evolution, metallothionein domains, tandem domain repeats, population variants, intra-species variability Author: Òscar Palacios and Ricard Albalat Creator: LaTeX with hyperref package Producer: pdfTeX-1.40.15 CreationDate: Mon Jun 28 11:26:41 2021 CEST ModDate: Mon Jun 28 17:17:27 2021 CEST Tagged: no UserProperties: no Suspects: no Form: none JavaScript: no Pages: 12 Encrypted: no Page size: 595.276 x 779.528 pts Page rot: 0 File size: 3964037 bytes Optimized: no PDF version: 1.6 name type encoding emb sub uni object ID ------------------------------------ ----------------- ---------------- --- --- --- --------- IJULVL+MinionPro-Regular Type 1 Custom yes yes no 28 0 WRMLYE+HelveticaNeueLTStd-Bd Type 1 Custom yes yes no 29 0 CQOXEU+HelveticaNeueLTStd-Lt Type 1 Custom yes yes no 30 0 WYUNLU+HelveticaNeueLTStd-BdIt Type 1 Custom yes yes no 35 0 KRHSEU+HelveticaNeueLTStd-LtIt Type 1 Custom yes yes no 36 0 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Materials and Methods Children: Item: Title: Production and Purification of Recombinant Metal-MT Complexes Item: Title: Analysis of Metal-MT Complexes Item: Title: Analysis of MT Variation Item: Title: Results and Discussion Children: Item: Title: Functional Analysis of the Modularity in OdiMTs Children: Item: Title: Metal-Binding Capabilities of 12C and t-12C Domains Item: Title: Metal-Binding Capabilities of t-12C/12C Repeats Item: Title: Genetic Variation in O. dioica MTs Item: Title: Data Availability Statement Item: Title: Author Contributions Item: Title: Funding Item: Title: Acknowledgments Item: Title: Supplementary Material Item: Title: References Filters: FilterPipeline: FlateDecode Fonts: Type1: Font: BaseFont: WYUNLU+HelveticaNeueLTStd-BdIt FontSubset: true FirstChar: 42 LastChar: 121 FontDescriptor: FontName: WYUNLU+HelveticaNeueLTStd-BdIt Flags: Symbolic FontBBox: -166, -218, 1129, 975 FontFile: true EncodingDictionary: Differences: true Font: BaseFont: 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thereby, a suitable system in which to explore the limits of evolutionary processes. 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