5cf629771f79b710b12d01a8ba0ab88e pmc_34434163.pdf ccd1442a6437af153e81de6686106df23c6e32e2 pmc_34434163.pdf 09f58c8504269da48f08d7feed5cec4d1d32b98828cfeccdfcbc1f968c1e740d pmc_34434163.pdf Title: Neuropsychological Assessments of Patients With Acquired Brain Injury: A Cluster Analysis Approach to Address Heterogeneity in Web-Based Cognitive Rehabilitation Subject: We[153mm]Q22 aimed to (1) apply cluster analysis techniques to mixed-type data (numerical and categorical) from baseline neuropsychological standard and widely used assessments of patients with acquired brain injury (ABI) (2) apply state-of-the-art cluster validity indexes (CVI) to assess their internal validity (3) study their external validity considering relevant aspects of ABI rehabilitation such as functional independence measure (FIM) in activities of daily life assessment (4) characterize the identified profiles by using demographic and clinically relevant variables and (5) extend the external validation of the obtained clusters to all cognitive rehabilitation tasks executed by the participants in a web-based cognitive rehabilitation platform (GNPT). Keywords: acquired brain injury, cluster analysis, cognitive rehabilitation, web-based platform, neuropsychological assessment, mixed-type data, functional independence Author: Alejandro Garcı́a-Rudolph Creator: LaTeX with hyperref package + hypdvips Producer: dvips + MiKTeX GPL Ghostscript 9.0 CreationDate: Tue Aug 3 12:28:44 2021 CEST ModDate: Tue Aug 3 13:06:34 2021 CEST Custom Metadata: no Metadata Stream: yes Tagged: no UserProperties: no Suspects: no Form: none JavaScript: no Pages: 14 Encrypted: no Page size: 595.26 x 779.52 pts Page rot: 0 File size: 886357 bytes Optimized: no PDF version: 1.6 name type encoding emb sub uni object ID ------------------------------------ ----------------- ---------------- --- --- --- --------- LWNREK+HelveticaNeueLTStd-Bd Type 1C Custom yes yes no 41 0 PUQFEL+HelveticaNeueLTStd-Lt Type 1C Custom yes yes no 46 0 PUGCYQ+HelveticaNeueLTStd-BdIt Type 1C WinAnsi yes yes no 59 0 SVFALA+HelveticaNeueLTStd-LtIt Type 1C Custom yes yes no 61 0 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FitWindow: true CenterWindow: false DisplayDocTitle: false NonFullScreenPageMode: UseNone Direction: L2R ViewArea: CropBox ViewClip: CropBox PrintArea: CropBox PageClip: CropBox PageLayout: SinglePage PageMode: UseOutlines Language: en Outlines: Item: Title: Neuropsychological Assessments of Patients With Acquired Brain Injury: A Cluster Analysis Approach to Address Heterogeneity in Web-Based Cognitive Rehabilitation Destination: ariclecounter.1 Children: Item: Title: Introduction Destination: section*.2 Item: Title: Materials and Methods Destination: section*.3 Children: Item: Title: Subject Selection Destination: section*.4 Item: Title: Procedure and Neuropsychological Measures at Admission Destination: section*.5 Item: Title: Web-Based Cognitive Rehabilitation Destination: section*.6 Item: Title: Statistical Analysis Destination: section*.7 Children: Item: Title: Data Pre-processing Destination: section*.8 Item: Title: Cluster Analysis Method: k-Prototypes Destination: section*.9 Item: Title: Optimal Number of Clusters: Internal Validation Destination: section*.10 Item: Title: Clusters Stability Destination: section*.11 Item: Title: External Validation Destination: section*.12 Item: Title: Post hoc Analyses Destination: section*.13 Item: Title: Results Destination: section*.14 Children: Item: Title: Demographic and Clinical Characteristics at Baseline Destination: section*.15 Item: Title: Preprocessing Phase: Correlation Analysis and z Normalization Destination: section*.16 Item: Title: Cluster Analysis: Internal Validation Destination: section*.17 Item: Title: Cluster Analysis: k-Prototypes Results Destination: section*.18 Item: Title: Stability Destination: section*.19 Item: Title: Cluster Analysis: External Validation Destination: section*.20 Item: Title: Discussion Destination: section*.21 Item: Title: Limitations of This Study Destination: section*.22 Item: Title: Conclusions Destination: section*.23 Item: Title: Data Availability Statement Destination: section*.24 Item: Title: Ethics Statement Destination: section*.25 Item: Title: Author Contributions Destination: section*.26 Item: Title: Funding Destination: section*.27 Item: Title: Supplementary Material Destination: section*.28 Item: Title: References Destination: section*.29 Info: Title: Neuropsychological Assessments of Patients With Acquired Brain Injury: A Cluster Analysis Approach to Address Heterogeneity in Web-Based Cognitive Rehabilitation Author: Alejandro Garcı́a-Rudolph Subject: We[153mm]Q22 aimed to (1) apply cluster analysis techniques to mixed-type data (numerical and categorical) from baseline neuropsychological standard and widely used assessments of patients with acquired brain injury (ABI) (2) apply state-of-the-art cluster validity indexes (CVI) to assess their internal validity (3) study their external validity considering relevant aspects of ABI rehabilitation such as functional independence measure (FIM) in activities of daily life assessment (4) characterize the identified profiles by using demographic and clinically relevant variables and (5) extend the external validation of the obtained clusters to all cognitive rehabilitation tasks executed by the participants in a web-based cognitive rehabilitation platform (GNPT). Keywords: acquired brain injury, cluster analysis, cognitive rehabilitation, web-based platform, neuropsychological assessment, mixed-type data, functional independence Creator: LaTeX with hyperref package + hypdvips Producer: dvips + MiKTeX GPL Ghostscript 9.0 CreationDate: Tue Aug 03 12:58:44 CEST 2021 ModDate: Tue Aug 03 13:36:34 CEST 2021 ID: 0x96e6363421082d19c3ed0a9a99e9f406, 0x0645cb30598e8649ab0d1cb9298cddaf Filters: FilterPipeline: FlateDecode FilterPipeline: DCTDecode Images: Image: NisoImageMetadata: FormatName: image/png ImageWidth: 279 ImageHeight: 279 ColorSpace: RGB BitsPerSample: 8 BitsPerSampleUnit: integer Filter: FlateDecode Image: NisoImageMetadata: FormatName: image/jpg CompressionScheme: JPEG ImageWidth: 1417 ImageHeight: 1408 ColorSpace: RGB BitsPerSample: 8 BitsPerSampleUnit: integer Interpolate: true Image: NisoImageMetadata: FormatName: image/jpg CompressionScheme: JPEG ImageWidth: 1772 ImageHeight: 819 ColorSpace: RGB BitsPerSample: 8 BitsPerSampleUnit: 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validity (3) study their external validity considering relevant aspects of ABI rehabilitation such as functional independence measure (FIM) in activities of daily life assessment (4) characterize the identified profiles by using demographic and clinically relevant variables and (5) extend the external validation of the obtained clusters to all cognitive rehabilitation tasks executed by the participants in a web-based cognitive rehabilitation platform (GNPT). Alejandro Garcı́a-Rudolph Neuropsychological Assessments of Patients With Acquired Brain Injury: A Cluster Analysis Approach to Address Heterogeneity in Web-Based Cognitive Rehabilitation acquired brain injury cluster analysis cognitive rehabilitation web-based platform neuropsychological assessment mixed-type data functional independence acquired brain injury, cluster analysis, cognitive rehabilitation, web-based platform, neuropsychological assessment, mixed-type data, functional independence dvips + MiKTeX GPL Ghostscript 9.0 uuid:2976bcdb-9f73-4b10-b0e6-c7e7f59a8021 uuid:897b7ecf-2d4e-43b6-8bf5-14bbb68ac9fd Pages: Page: Label: 1 Annotations: Annotation: Subtype: Link Rect: 43, 719, 144, 755 Annotation: Subtype: Link Rect: 474, 736, 551, 744 Annotation: Subtype: Link Rect: 468, 728, 510, 736 Annotation: Subtype: Link Rect: 510, 728, 533, 736 Annotation: Subtype: Link Rect: 533, 728, 551, 736 Annotation: Subtype: Link Rect: 451, 720, 551, 728 Annotation: Subtype: Link Rect: 521, 678, 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