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Title:          Aberrant perineuronal nets alter spinal circuits, impair motor function, and increase plasticity
Subject:        Experimental Neurology, 358 (2022) 114220. doi:10.1016/j.expneurol.2022.114220
Keywords:       Perineuronal nets,Link protein 1,Plasticity,Locomotion,Spinal cord injury
Author:         J. Sánchez-Ventura
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      Title: Aberrant perineuronal nets alter spinal circuits, impair motor function, and increase plasticity
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        Title: 1 Introduction
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        Title: 2 Materials and methods
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          Title: 2.1 Experimental design
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          Title: 2.2 Genotyping
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          Title: 2.3 Functional assessment
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        Title: 3 Results
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          Title: 3.1 The lack of link protein 1 altered PNN composition in the spinal cord
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          Title: 3.2 Crtl1 KO mice presented reduced body weight and hypoactivity
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          Title: 3.3 Animals lacking link protein 1 displayed impaired locomotion, motor coordination and abnormal gait performance
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          Title: 3.4 Crtl1 KO mice presented increased excitability of spinal reflexes
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          Title: 3.5 Mice with aberrant PNNs exhibited a general increase in excitatory but not inhibitory synapses
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          Title: 3.6 Altered PNNs modified the lumbar motoneuron size and motor unit properties
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          Title: 3.7 Crtl1 KO mice displayed increased corticospinal sprouting after spinal cord injury
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          Title: 4.2 Aberrant PNNs increase the excitability of spinal circuits
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          Title: 4.4 Aberrant PNNs increase sprouting after spinal cord injury
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        Title: 5 Conclusion
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        Title: Author contribution
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        Title: Declaration of Competing Interest
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        Title: Data availability
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        Title: Acknowledgments
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        Title: References
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   Type: CRC32
  Checksum: 3a65dcc20e737074b7db00e54bec86e4
   Type: MD5
  Checksum: f116e1fb7dd78d59004f6573e41e0cecb19f19c2
   Type: SHA-1