4365b3d2bd72f3548fc7b06aab6a5d3f natcom_a2022m5v13p2608.pdf b880ba01281869cc7c852bee46597b63c11c0813 natcom_a2022m5v13p2608.pdf 4cdb41e75e0310f92eac9b00bcaa10075110ae8a856c731bdc1ee8c5397bb3cf natcom_a2022m5v13p2608.pdf Title: 3D chromatin remodelling in the germ line modulates genome evolutionary plasticity Subject: Nature Communications, doi:10.1038/s41467-022-30296-6 Keywords: Author: Lucía Álvarez-González Creator: Springer Producer: iText® 5.3.5 ©2000-2012 1T3XT BVBA (SPRINGER SBM; licensed version) CreationDate: Thu May 5 18:12:07 2022 CEST ModDate: Thu May 5 21:38:54 2022 CEST Tagged: no UserProperties: no Suspects: no Form: AcroForm JavaScript: no Pages: 15 Encrypted: no Page size: 595.276 x 782.362 pts Page rot: 0 File size: 5241641 bytes Optimized: no PDF version: 1.4 name type encoding emb sub uni object ID ------------------------------------ ----------------- ---------------- --- --- --- --------- FMGDEC+AdvTTda6f6cb8.B Type 1C WinAnsi yes yes no 104 0 FMGBLG+AdvOTea1a7398 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edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR69' cannot be found Offset: 4774964 MIMEtype: application/pdf PDFMetadata: Objects: 1014 FreeObjects: 1 IncrementalUpdates: 0 DocumentCatalog: PageLayout: SinglePage PageMode: UseOutlines Language: EN Outlines: Item: Title: 3D chromatin remodelling in the germ line modulates genome evolutionary plasticity Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@4eb7f003 Children: Item: Title: Results Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@eafc191 Children: Item: Title: Patterns of chromosome rearrangements in rodents Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@612fc6eb Item: Title: Epigenetic landscape dynamics during mouse spermatogenesis Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@1060b431 Item: Title: EBRs associate with open chromatin environments activated during meiosis Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@612679d6 Item: Title: Chromosome rearrangements do not disturb meiotic chromosomal architecture in prophase I Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@11758f2a Item: Title: EBRs associate with DNA damage in post-meiotic cells Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@e720b71 Item: Title: Functional features of post-meiotic cell-specific long-range genomic interactions Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@1b26f7b2 Item: Title: Long-range genomic interactions in round spermatids recapitulate ancestral chromosomal configurations Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@491cc5c9 Item: Title: Discussion Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@74ad1f1f Item: Title: Methods Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@6a1aab78 Children: Item: Title: Ancestral karyotype reconstruction Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@462d5aee Item: Title: Detection of Evolutionary Breakpoint Regions (EBRs) Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@69b0fd6f Item: Title: Histone, ATAC and DSBs profiles Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@757942a1 Item: Title: Hi-C data Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@4a87761d Item: Title: Long-range interactions Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@66d1af89 Item: Title: Gene ontology enrichment Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@8646db9 Item: Title: Differentially expressed genes Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@37374a5e Item: Title: Multi-association analyses Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@4671e53b Item: Title: Quantification and statistical analysis Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@2db7a79b Item: Title: Reporting summary Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@6950e31 Item: Title: Data availability Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@b7dd107 Item: Title: References Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@42eca56e Item: Title: Code availability Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@52f759d7 Item: Title: References Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@7cbd213e Item: Title: References Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@192d3247 Item: Title: Acknowledgements Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@3ecd23d9 Item: Title: Author contributions Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@569cfc36 Item: Title: Competing interests Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@43bd930a 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FMGGOF+MyriadPro-Regular Flags: Nonsymbolic FontBBox: -157, -250, 1126, 952 FontFile3: true Encoding: WinAnsiEncoding XMP: application/pdf doi:10.1038/s41467-022-30296-6 3D chromatin remodelling in the germ line modulates genome evolutionary plasticity Lucía Álvarez-González Frances Burden Dadakhalandar Doddamani Roberto Malinverni Emma Leach Cristina Marín-García Laia Marín-Gual Albert Gubern Covadonga Vara Andreu Paytuví-Gallart Marcus Buschbeck Peter J. I. Ellis Marta Farré Aurora Ruiz-Herrera Springer US Nature Communications, doi:10.1038/s41467-022-30296-6 Springer 2022-05-05T21:38:54+02:00 2022-05-05T21:42:07+05:30 2022-05-05T21:38:54+02:00 True iText® 5.3.5 ©2000-2012 1T3XT BVBA (SPRINGER SBM; licensed version) uuid:938c90ee-89c8-4175-b1e8-690e53cbd917 uuid:ef8eea12-dc51-4cb0-a20e-60ab5478a45b default 1 converted uuid:6fa91e69-c113-4f69-aef9-a2408e496b99 converted to PDF/A-2b pdfToolbox 2022-05-05T21:43:02+05:30 2 B http://ns.adobe.com/pdf/1.3/ pdf Adobe PDF Schema internal A name object indicating whether the document has been modified to include trapping information Trapped Text http://ns.adobe.com/pdfx/1.3/ pdfx Adobe Document Info PDF eXtension Schema internal ID of PDF/X standard GTS_PDFXVersion Text internal Conformance level of PDF/X standard GTS_PDFXConformance Text internal Company creating the PDF Company Text internal Date when document was last modified SourceModified Text http://ns.adobe.com/xap/1.0/mm/ xmpMM XMP Media Management Schema internal UUID based identifier for specific incarnation of a document InstanceID URI internal The common identifier for all versions and renditions of a document. 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