dac8fd0c9742ceb9d2af573bd61ef177 scitotenv_a2022m10v842p156923.pdf d0e3b18c4f4d96cff33ab36622a320862ae5f069 scitotenv_a2022m10v842p156923.pdf b7b5b21f3a87b1eb358feb77416b6bf2a3f9c2de5aa4b2a186f79e9700515237 scitotenv_a2022m10v842p156923.pdf Title: Antagonistic in vivo interaction of polystyrene nanoplastics and silver compounds. A study using Drosophila Subject: Science of the Total Environment, 842 (2022) 156923. doi:10.1016/j.scitotenv.2022.156923 Keywords: Nanoplastics; Polystyrene; Silver nanoparticles; Carriers; Size; Uptake; Oxidative stress; Genotoxicity; Antagonistic interaction; Drosophila melanogaster Author: Mohamed Alaraby Creator: Elsevier CreationDate: Wed Jun 29 09:30:34 2022 CEST ModDate: Wed Jun 29 09:30:34 2022 CEST Tagged: no UserProperties: no Suspects: no Form: AcroForm JavaScript: no Pages: 12 Encrypted: no Page size: 595.276 x 793.701 pts Page rot: 0 File size: 2983605 bytes Optimized: yes PDF version: 1.7 name type encoding emb sub uni object ID ------------------------------------ ----------------- ---------------- --- --- --- --------- GEMLGL+AdvTTe692faf0 Type 1C WinAnsi yes yes no 509 0 GEMLGM+AdvTT47f7fe79.I Type 1C WinAnsi yes yes no 510 0 GEMLGN+AdvTT8608a8d1+20 Type 1C Custom yes yes yes 511 0 GEMLGO+AdvTTe692faf0+20 Type 1C Custom yes yes yes 512 0 GEMLNN+AdvTTe692faf0+22 Type 1C Custom yes yes yes 527 0 GEMLNO+AdvTTe692faf0+fb Type 1C Custom yes yes yes 528 0 GEMLPO+AdvTTc8c83e50 Type 1C WinAnsi yes yes no 529 0 GEMMGO+AdvTTe692faf0+03 Type 1C Custom yes yes yes 239 0 GEMMFN+AdvTTc9617e0c.B Type 1C WinAnsi yes yes no 240 0 GEMMFO+AdvTTe692faf0+01 Type 1C WinAnsi yes yes no 243 0 GEMMIO+AdvTTe692faf0+21 Type 1C WinAnsi yes yes no 244 0 GEMMKP+AdvTT8608a8d1 Type 1C WinAnsi yes yes no 245 0 GEMNLJ+AdvP0023 Type 1C WinAnsi yes yes no 256 0 GEMNNK+Arial-BoldMT Type 1C WinAnsi yes yes no 253 0 GEMNNL+ArialMT Type 1C WinAnsi yes yes no 255 0 CambriaMath Type 1C Custom yes no yes 257 0 GENBDI+Arial-BoldItalicMT Type 1C WinAnsi yes yes no 259 0 GENBJH+TimesNewRomanPSMT Type 1C WinAnsi yes yes no 260 0 Jhove (Rel. 1.22.1, 2019-04-17) Date: 2022-07-29 02:36:40 CEST RepresentationInformation: scitotenv_a2022m10v842p156923.pdf ReportingModule: PDF-hul, Rel. 1.12.1 (2019-04-17) LastModified: 2022-07-28 19:23:06 CEST Size: 2983605 Format: PDF Version: 1.7 Status: Well-Formed and valid SignatureMatches: PDF-hul MIMEtype: application/pdf Profile: Linearized PDF PDFMetadata: Objects: 593 FreeObjects: 1 IncrementalUpdates: 1 DocumentCatalog: PageLayout: SinglePage PageMode: UseOutlines Language: en Outlines: Item: Title: Antagonistic in vivo interaction of polystyrene nanoplastics and silver compounds. A study using Drosophila Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@6121c9d6 Children: Item: Title: 1. Introduction Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@87f383f Item: Title: 2. Materials and methods Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@4eb7f003 Children: Item: Title: 2.1. Silver and polystyrene nanoparticles characterization Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@eafc191 Item: Title: 2.2. Drosophila melanogaster exposure Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@612fc6eb Item: Title: 2.3. Toxicity Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@1060b431 Item: Title: 2.4. AgNPs and PSNPLs internalization Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@612679d6 Children: Item: Title: 2.4.1. TEM investigation Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@11758f2a Item: Title: 2.4.2. Internalization by ICPMS Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@e720b71 Item: Title: 2.5. Alteration of gene expression levels Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@1b26f7b2 Item: Title: 2.6. Detection of oxidative stress induction Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@491cc5c9 Item: Title: 2.7. DNA damage induction Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@74ad1f1f Item: Title: 2.8. Statistical analysis Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@6a1aab78 Item: Title: 3. Results Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@462d5aee Children: Item: Title: 3.1. Characterization of AgNPs and PSNPLs Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@69b0fd6f Item: Title: 3.2. Drosophila viability after exposures Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@757942a1 Item: Title: 3.3. Internalization of silver compounds and PSNPLs Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@4a87761d Children: Item: Title: 3.3.1. Silver content detection in larval body by using ICP-MS Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@66d1af89 Item: Title: 3.3.2. PSNPLs/silver internalization detection by using TEM Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@8646db9 Children: Item: Title: 3.3.2.1. PSNPLs (PS-50 and PS-500) internalization Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@37374a5e Item: Title: 3.3.2.2. PS-50/AgNPs internalization Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@4671e53b Item: Title: 3.3.2.3. PS-500/AgNPs internalization Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@2db7a79b Item: Title: 3.4. Gene expression changes Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@6950e31 Item: Title: 3.5. Oxidative stress induction Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@b7dd107 Item: Title: 3.6. Genotoxic impact evaluated in the comet assay Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@42eca56e Item: Title: 4. Discussion Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@52f759d7 Item: Title: 5. Conclusions Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@7cbd213e Item: Title: CRediT authorship contribution statement Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@192d3247 Item: Title: Declaration of competing interest Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@3ecd23d9 Item: Title: Acknowledgments Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@569cfc36 Item: Title: References Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@43bd930a Info: Title: Antagonistic in vivo interaction of polystyrene nanoplastics and silver compounds. A study using Drosophila Author: Mohamed Alaraby Subject: Science of the Total Environment, 842 (2022) 156923. doi:10.1016/j.scitotenv.2022.156923 Keywords: Nanoplastics; Polystyrene; Silver nanoparticles; Carriers; Size; Uptake; Oxidative stress; Genotoxicity; Antagonistic interaction; Drosophila melanogaster Creator: Elsevier CreationDate: Wed Jun 29 09:30:34 CEST 2022 ModDate: Wed Jun 29 09:30:34 CEST 2022 ID: 0x7ad6a867a0e50429d41d4bc57bdb738f, 0x16b45b4723d07846946244377e58ab69 Filters: FilterPipeline: FlateDecode FilterPipeline: DCTDecode Images: Image: NisoImageMetadata: FormatName: image/png ImageWidth: 190 ImageHeight: 370 BitsPerSample: 8 BitsPerSampleUnit: integer Filter: FlateDecode Image: NisoImageMetadata: FormatName: image/jpg CompressionScheme: JPEG ImageWidth: 245 ImageHeight: 269 ColorSpace: CMYK BitsPerSample: 8 BitsPerSampleUnit: integer Image: NisoImageMetadata: FormatName: image/jpg CompressionScheme: JPEG ImageWidth: 236 ImageHeight: 298 ColorSpace: RGB 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and silver compounds. A study using Drosophila Mohamed Alaraby Doaa Abass Aliro Villacorta Alba Hernández Ricard Marcos Nanoplastics Polystyrene Silver nanoparticles Carriers Size Uptake Oxidative stress Genotoxicity Antagonistic interaction Drosophila melanogaster Science of the Total Environment, 842 (2022) 156923. doi:10.1016/j.scitotenv.2022.156923 The Authors journal Science of the Total Environment (c) 2022 The Authors All rights reserved 0048-9697 842 10 October 2022 2022-10-10 156923 156923 10.1016/j.scitotenv.2022.156923 https://doi.org/10.1016/j.scitotenv.2022.156923 2010-04-23 true 10.1016/j.scitotenv.2022.156923 elsevier.com sciencedirect.com VoR 10.1016/j.scitotenv.2022.156923 noindex 2010-04-23 true elsevier.com sciencedirect.com Elsevier 2022-06-29T07:30:34Z 2022-06-29T07:30:34Z 2022-06-29T07:30:34Z True Nanoplastics; Polystyrene; Silver nanoparticles; Carriers; Size; Uptake; Oxidative stress; Genotoxicity; Antagonistic interaction; Drosophila melanogaster 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Subtype: Link Rect: 394, 447, 557, 453 Annotation: Subtype: Link Rect: 318, 439, 502, 445 Annotation: Subtype: Link Rect: 427, 415, 555, 421 Annotation: Subtype: Link Rect: 384, 391, 502, 397 Annotation: Subtype: Link Rect: 396, 367, 488, 373 Annotation: Subtype: Link Rect: 318, 335, 452, 341 Annotation: Subtype: Link Rect: 410, 311, 546, 318 Annotation: Subtype: Link Rect: 458, 287, 557, 294 Annotation: Subtype: Link Rect: 318, 279, 354, 286 Annotation: Subtype: Link Rect: 536, 255, 557, 262 Annotation: Subtype: Link Rect: 318, 247, 429, 254 Annotation: Subtype: Link Rect: 461, 224, 557, 230 Annotation: Subtype: Link Rect: 318, 216, 354, 222 Annotation: Subtype: Link Rect: 409, 192, 534, 198 Annotation: Subtype: Link Rect: 318, 168, 446, 174 Checksum: 3ef4bfdb Type: CRC32 Checksum: dac8fd0c9742ceb9d2af573bd61ef177 Type: MD5 Checksum: d0e3b18c4f4d96cff33ab36622a320862ae5f069 Type: SHA-1