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Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@757942a1 Item: Title: 3.3 Mammalian cells: Human embryonic kidney (HEK) cells Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@4a87761d Item: Title: 3.4 Avian cells Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@66d1af89 Item: Title: 4 TGE systems and their differences regarding the CDE Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@8646db9 Children: Item: Title: 4.1 DNA complexation-based transient expression systems Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@37374a5e Item: Title: 4.2 Electroporation Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@4671e53b Item: Title: 4.3 Viral transient expression systems Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@2db7a79b Item: Title: 5 The evolution of the CDE research Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@6950e31 Item: Title: 6 The role of energy metabolism in the CDE Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@b7dd107 Item: Title: 7 Achieving successful transient expression at high cell densities Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@42eca56e Children: Item: Title: 7.1 Cell concentration followed by transfection and subsequent dilution Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@52f759d7 Item: Title: 7.2 Dilution followed by transfection Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@7cbd213e Item: Title: 7.3 Cell concentration followed by transient expression Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@192d3247 Item: Title: 7.4 Infections at HCD in perfusion mode Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@3ecd23d9 Item: Title: 8 Current state and perspectives Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@569cfc36 Item: Title: Author contributions Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@43bd930a Item: Title: Funding Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@33723e30 Item: Title: CRediT authorship contribution statement Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@64f6106c Item: Title: Declaration of Competing Interest Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@553a3d88 Item: Title: Data availability Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@7a30d1e6 Item: Title: References Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@5891e32e Info: Title: The cell density effect in animal cell-based bioprocessing: Questions, insights and perspectives Author: Jesús Lavado-García Subject: Biotechnology Advances, 60 (2022) 108017. doi:10.1016/j.biotechadv.2022.108017 Keywords: Cell density effect,Infection,Transient transfection,Perfusion Creator: Elsevier Producer: Acrobat Distiller 8.1.0 (Windows) CreationDate: Thu Sep 22 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Biotechnology Advances, 60 (2022) 108017. doi:10.1016/j.biotechadv.2022.108017 Cell density effect Infection Transient transfection Perfusion The cell density effect in animal cell-based bioprocessing: Questions, insights and perspectives Jesús Lavado-García Pol Pérez-Rubio Laura Cervera Francesc Gòdia journal Biotechnology Advances © 2022 The Authors. Published by Elsevier Inc. 0734-9750 60 1 November 2022 2022-11-01 108017 108017 10.1016/j.biotechadv.2022.108017 https://doi.org/10.1016/j.biotechadv.2022.108017 2010-04-23 true 10.1016/j.biotechadv.2022.108017 elsevier.com sciencedirect.com http://creativecommons.org/licenses/by-nc-nd/4.0/ VoR 10.1016/j.biotechadv.2022.108017 noindex 2010-04-23 true 22nd September 2022 sciencedirect.com elsevier.com Elsevier 2022-09-22T07:53:38 2022-09-22T07:35:02 2022-09-22T07:53:38 True 22nd September 2022 Acrobat Distiller 8.1.0 (Windows) Cell density effect,Infection,Transient transfection,Perfusion uuid:1b499bed-4ce8-4c0c-b682-0d58baae1cbe uuid:b6ed5266-03cb-4855-90c0-636283357f42 Pages: Page: Label: 1 Annotations: Annotation: Subtype: Link Rect: 134, 576, 141, 586 Flags: Print Destination: 1594 Annotation: Subtype: Link Rect: 141, 576, 148, 586 Flags: Print Destination: 1594 Annotation: Subtype: Link Rect: 149, 576, 156, 586 Flags: Print Destination: 1594 Annotation: Subtype: Link Rect: 156, 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