e1b8248b7418235700ed1509b7b1e03b  270619.pdf
2a65274c6524d5e534d3d3571cea111a3b32d6dd  270619.pdf
dac4238c7fdb95dfb565749f5b335e6bbc98320757520b2743080dcc60ad582a  270619.pdf

Title:          Targeting the MYC interaction network in B-cell lymphoma via histone deacetylase 6 inhibition
Subject:        Oncogene, doi:10.1038/s41388-022-02450-3
Keywords:       
Author:         René Winkler
Creator:        Springer
CreationDate:   Sat Sep 24 10:33:34 2022 CEST
ModDate:        Sat Sep 24 10:34:02 2022 CEST
Tagged:         no
UserProperties: no
Suspects:       no
Form:           AcroForm
JavaScript:     no
Pages:          13
Encrypted:      no
Page size:      595.276 x 790.866 pts
Page rot:       0
File size:      2788636 bytes
Optimized:      yes
PDF version:    1.4


name                                 type              encoding         emb sub uni object ID
------------------------------------ ----------------- ---------------- --- --- --- ---------
EKNFHP+AdvTT5afe5d37.B               Type 1C           WinAnsi          yes yes no     720  0
EKNGNA+AdvOT3b30f6db.B               Type 1C           WinAnsi          yes yes no     734  0
EKNGNB+AdvOT46dcae81+20              Type 1C           Custom           yes yes yes    735  0
EKNGOB+AdvOTa20b42a7                 Type 1C           WinAnsi          yes yes no     753  0
EKNFJP+Arial-BoldMT                  Type 1C           WinAnsi          yes yes no     721  0
EKNFLP+AdvOT46dcae81                 Type 1C           WinAnsi          yes yes no     728  0
EKNFMA+AdvTT6780a46b                 Type 1C           WinAnsi          yes yes no     729  0
EKNGLL+AdvTT2876772e+27              Type 1C           Custom           yes yes yes    736  0
EKNGMM+AdvOT65f8a23b.I               Type 1C           WinAnsi          yes yes no     737  0
EKNGMN+AdvOT46dcae81+fb              Type 1C           Custom           yes yes yes    738  0
EKNGMO+AdvMyriad_I                   Type 1C           WinAnsi          yes yes no     739  0
EKNGMP+AdvMyriad_R                   Type 1C           WinAnsi          yes yes no     740  0
EKNHBB+AdvTTab7e17fd                 Type 1C           WinAnsi          yes yes no     306  0
EKNHBC+AdvOT3b30f6db.B+fb            Type 1C           Custom           yes yes yes    307  0
EKNHBD+AdvOT7d2ebc01                 Type 1C           WinAnsi          yes yes no     301  0
EKNHNA+ArialMT                       Type 1C           Custom           yes yes yes    326  0
EKNIAP+Arial-ItalicMT                Type 1C           WinAnsi          yes yes no     330  0
EKNIDP+AdvOT919a0533.B               Type 1C           WinAnsi          yes yes no     325  0
EKNIEA+AdvTT6780a46b+fb              Type 1C           Custom           yes yes yes    331  0
EKNIEB+AdvTT6780a46b+20              Type 1C           WinAnsi          yes yes no     323  0
EKNJIK+AdvOT8608a8d1+03              Type 1C           Custom           yes yes yes    341  0
EKNLBC+AdvOT46dcae81+03              Type 1C           Custom           yes yes yes    410  0
Arial-BoldItalicMT                   Type 1C           WinAnsi          yes no  no     411  0
EKNPJI+AdvTTab7e17fd+22              Type 1C           Custom           yes yes yes    412  0
Calibri                              Type 1C           WinAnsi          yes no  no     413  0
EKOECO+AdvOT3b30f6db.B+20            Type 1C           WinAnsi          yes yes no     424  0


Jhove (Rel. 1.22.1, 2019-04-17)
 Date: 2023-05-27 02:37:05 CEST
 RepresentationInformation: 270619.pdf
  ReportingModule: PDF-hul, Rel. 1.12.1 (2019-04-17)
  LastModified: 2023-05-26 11:01:55 CEST
  Size: 2788636
  Format: PDF
  Version: 1.4
  Status: Well-Formed, but not valid
  SignatureMatches:
   PDF-hul
  ID: PDF-HUL-122
  ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR4' cannot be found
   Offset: 2755443
  ID: PDF-HUL-122
  ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR10' cannot be found
   Offset: 2755443
  ID: PDF-HUL-122
  ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR11' cannot be found
   Offset: 2755443
  ID: PDF-HUL-122
  ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR11' cannot be found
   Offset: 2755443
  ID: PDF-HUL-122
  ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR12' cannot be found
   Offset: 2755443
  ID: PDF-HUL-122
  ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR14' cannot be found
   Offset: 2755443
  ID: PDF-HUL-122
  ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR15' cannot be found
   Offset: 2755443
  ID: PDF-HUL-122
  ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR16' cannot be found
   Offset: 2755443
  ID: PDF-HUL-122
  ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR13' cannot be found
   Offset: 2755443
  ID: PDF-HUL-122
  ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR17' cannot be found
   Offset: 2755443
  ID: PDF-HUL-122
  ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR18' cannot be found
   Offset: 2755443
  ID: PDF-HUL-122
  ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR19' cannot be found
   Offset: 2755443
  ID: PDF-HUL-122
  ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR20' cannot be found
   Offset: 2755443
  ID: PDF-HUL-122
  ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR21' cannot be found
   Offset: 2755443
  ID: PDF-HUL-122
  ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR22' cannot be found
   Offset: 2755443
  ID: PDF-HUL-122
  ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR23' cannot be found
   Offset: 2755443
  ID: PDF-HUL-122
  ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR22' cannot be found
   Offset: 2755443
  ID: PDF-HUL-122
  ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR23' cannot be found
   Offset: 2755443
  ID: PDF-HUL-122
  ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR22' cannot be found
   Offset: 2755443
  ID: PDF-HUL-122
  ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR24' cannot be found
   Offset: 2755443
  ID: PDF-HUL-122
  ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR22' cannot be found
   Offset: 2755443
  ID: PDF-HUL-122
  ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR23' cannot be found
   Offset: 2755443
  ID: PDF-HUL-122
  ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR22' cannot be found
   Offset: 2755443
  ID: PDF-HUL-122
  ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR22' cannot be found
   Offset: 2755443
  ID: PDF-HUL-122
  ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR25' cannot be found
   Offset: 2755443
  ID: PDF-HUL-122
  ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR26' cannot be found
   Offset: 2755443
  ID: PDF-HUL-122
  ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR27' cannot be found
   Offset: 2755443
  ID: PDF-HUL-122
  ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR28' cannot be found
   Offset: 2755443
  ID: PDF-HUL-122
  ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR29' cannot be found
   Offset: 2755443
  ID: PDF-HUL-122
  ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR30' cannot be found
   Offset: 2755443
  ID: PDF-HUL-122
  ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR35' cannot be found
   Offset: 2755443
  ID: PDF-HUL-122
  ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR36' cannot be found
   Offset: 2755443
  ID: PDF-HUL-122
  ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR37' cannot be found
   Offset: 2755443
  ID: PDF-HUL-122
  ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR38' cannot be found
   Offset: 2755443
  ID: PDF-HUL-122
  ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR39' cannot be found
   Offset: 2755443
  ID: PDF-HUL-122
  ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR40' cannot be found
   Offset: 2755443
  ID: PDF-HUL-122
  ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR41' cannot be found
   Offset: 2755443
  ID: PDF-HUL-122
  ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR42' cannot be found
   Offset: 2755443
  ID: PDF-HUL-122
  ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR43' cannot be found
   Offset: 2755443
  ID: PDF-HUL-122
  ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR45' cannot be found
   Offset: 2755443
  ID: PDF-HUL-122
  ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR46' cannot be found
   Offset: 2755443
  ID: PDF-HUL-122
  ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR47' cannot be found
   Offset: 2755443
  ID: PDF-HUL-122
  ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR40' cannot be found
   Offset: 2755443
  ID: PDF-HUL-122
  ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR18' cannot be found
   Offset: 2755443
  ID: PDF-HUL-122
  ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR48' cannot be found
   Offset: 2755443
  ID: PDF-HUL-122
  ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR48' cannot be found
   Offset: 2755443
  ID: PDF-HUL-122
  ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR13' cannot be found
   Offset: 2755443
  ID: PDF-HUL-122
  ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR22' cannot be found
   Offset: 2755443
  ID: PDF-HUL-122
  ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR50' cannot be found
   Offset: 2755443
  ID: PDF-HUL-122
  ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR51' cannot be found
   Offset: 2755443
  ID: PDF-HUL-122
  ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR52' cannot be found
   Offset: 2755443
  ID: PDF-HUL-122
  ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR53' cannot be found
   Offset: 2755443
  ID: PDF-HUL-122
  ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR54' cannot be found
   Offset: 2755443
  ID: PDF-HUL-122
  ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR23' cannot be found
   Offset: 2755443
  ID: PDF-HUL-122
  ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR55' cannot be found
   Offset: 2755443
  ID: PDF-HUL-122
  ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR56' cannot be found
   Offset: 2755443
  ID: PDF-HUL-122
  ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR57' cannot be found
   Offset: 2755443
  ID: PDF-HUL-122
  ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR58' cannot be found
   Offset: 2755443
  ID: PDF-HUL-122
  ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR59' cannot be found
   Offset: 2755443
  ID: PDF-HUL-122
  ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bm_CR60' cannot be found
   Offset: 2755443
  MIMEtype: application/pdf
  Profile: Linearized PDF
  PDFMetadata: 
   Objects: 856
   FreeObjects: 1
   IncrementalUpdates: 1
   DocumentCatalog: 
    PageLayout: SinglePage
    PageMode: UseOutlines
    Outlines: 
     Item: 
      Title: Targeting the MYC interaction network in B-nobreakcell lymphoma via histone deacetylase 6 inhibition
      Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@6121c9d6
      Children: 
       Item: 
        Title: Introduction
        Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@87f383f
       Item: 
        Title: Results
        Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@4eb7f003
        Children: 
         Item: 
          Title: HDAC6 inhibition increases the survival of lymphoma-prone mice
          Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@eafc191
         Item: 
          Title: Inhibition of HDAC6’specifically induces apoptosis in B-nobreakcell lymphoma
          Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@612fc6eb
         Item: 
          Title: HDAC6 inhibition results in apoptosis of human B-nobreakcell lymphoma cells
          Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@1060b431
         Item: 
          Title: HDAC6 inhibition causes MYC degradation
          Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@612679d6
         Item: 
          Title: MYC degradation is associated with changes in the interactome of hyperacetylated tubulin
          Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@11758f2a
         Item: 
          Title: The chaperone DNAJA3 is recruited to acetylated tubulin and induces MYC degradation
          Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@e720b71
       Item: 
        Title: Discussion
        Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@1b26f7b2
       Item: 
        Title: Materials and methods
        Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@491cc5c9
        Children: 
         Item: 
          Title: In vivo animal studies
          Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@74ad1f1f
         Item: 
          Title: Cell lines and primary cultures
          Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@6a1aab78
         Item: 
          Title: Flow cytometry
          Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@462d5aee
         Item: 
          Title: Immunoprecipitation
          Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@69b0fd6f
         Item: 
          Title: Proximity ligation assay
          Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@757942a1
         Item: 
          Title: Proteomics
          Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@4a87761d
       Item: 
        Title: Acknowledgements
        Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@66d1af89
       Item: 
        Title: Author contributions
        Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@8646db9
       Item: 
        Title: Funding
        Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@37374a5e
       Item: 
        Title: Competing interests
        Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@4671e53b
       Item: 
        Title: ADDITIONAL INFORMATION
        Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@2db7a79b
   Info: 
    Title: Targeting the MYC interaction network in B-cell lymphoma via histone deacetylase 6 inhibition
    Author: René Winkler
    Subject: Oncogene, doi:10.1038/s41388-022-02450-3
    Keywords: 
    Creator: Springer
    CreationDate: Sat Sep 24 11:03:34 CEST 2022
    ModDate: Sat Sep 24 11:04:02 CEST 2022
   ID: 0x35f169ec28331fa51c435fa949d7d97f, 0xabddb507d8362c4ba7a111d4d79b85c9
   Filters: 
    FilterPipeline: FlateDecode
    FilterPipeline: DCTDecode
   Images: 
    Image: 
     NisoImageMetadata: 
      FormatName: image/jpg
      CompressionScheme: JPEG
      ImageWidth: 1436
      ImageHeight: 332
      ColorSpace: CMYK
      BitsPerSample: 8
      BitsPerSampleUnit: integer
    Image: 
     NisoImageMetadata: 
      FormatName: image/png
      ImageWidth: 1119
      ImageHeight: 488
      BitsPerSample: 8
      BitsPerSampleUnit: integer
     Filter: FlateDecode
    Image: 
     NisoImageMetadata: 
      FormatName: image/png
      ImageWidth: 404
      ImageHeight: 725
      BitsPerSample: 8
      BitsPerSampleUnit: integer
     Filter: FlateDecode
    Image: 
     NisoImageMetadata: 
      FormatName: image/jpg
      CompressionScheme: JPEG
      ImageWidth: 493
      ImageHeight: 581
      BitsPerSample: 8
      BitsPerSampleUnit: integer
    Image: 
     NisoImageMetadata: 
      FormatName: image/jpg
      CompressionScheme: JPEG
      ImageWidth: 147
      ImageHeight: 193
      BitsPerSample: 8
      BitsPerSampleUnit: integer
    Image: 
     NisoImageMetadata: 
      FormatName: image/png
      ImageWidth: 528
      ImageHeight: 193
      BitsPerSample: 8
      BitsPerSampleUnit: integer
     Filter: FlateDecode
    Image: 
     NisoImageMetadata: 
      FormatName: image/png
      ImageWidth: 1403
      ImageHeight: 348
      BitsPerSample: 8
      BitsPerSampleUnit: integer
     Filter: FlateDecode
    Image: 
     NisoImageMetadata: 
      FormatName: image/png
      ImageWidth: 1481
      ImageHeight: 209
      BitsPerSample: 8
      BitsPerSampleUnit: integer
     Filter: FlateDecode
    Image: 
     NisoImageMetadata: 
      FormatName: image/jpg
      CompressionScheme: JPEG
      ImageWidth: 490
      ImageHeight: 245
      BitsPerSample: 8
      BitsPerSampleUnit: integer
    Image: 
     NisoImageMetadata: 
      FormatName: image/jpg
      CompressionScheme: JPEG
      ImageWidth: 254
      ImageHeight: 531
      BitsPerSample: 8
      BitsPerSampleUnit: integer
    Image: 
     NisoImageMetadata: 
      FormatName: image/png
      ImageWidth: 810
      ImageHeight: 590
      BitsPerSample: 8
      BitsPerSampleUnit: integer
     Filter: FlateDecode
    Image: 
     NisoImageMetadata: 
      FormatName: image/jpg
      CompressionScheme: JPEG
      ImageWidth: 1009
      ImageHeight: 361
      ColorSpace: CMYK
      BitsPerSample: 8
      BitsPerSampleUnit: integer
    Image: 
     NisoImageMetadata: 
      FormatName: image/jpg
      CompressionScheme: JPEG
      ImageWidth: 1440
      ImageHeight: 686
      ColorSpace: CMYK
      BitsPerSample: 8
      BitsPerSampleUnit: integer
    Image: 
     NisoImageMetadata: 
      FormatName: image/jpg
      CompressionScheme: JPEG
      ImageWidth: 1657
      ImageHeight: 261
      ColorSpace: CMYK
      BitsPerSample: 8
      BitsPerSampleUnit: integer
    Image: 
     NisoImageMetadata: 
      FormatName: image/png
      ImageWidth: 1402
      ImageHeight: 664
      ColorSpace: CMYK
      BitsPerSample: 8
      BitsPerSampleUnit: integer
     Filter: FlateDecode
    Image: 
     NisoImageMetadata: 
      FormatName: image/png
      ImageWidth: 1416
      ImageHeight: 259
      ColorSpace: CMYK
      BitsPerSample: 8
      BitsPerSampleUnit: integer
     Filter: FlateDecode
    Image: 
     NisoImageMetadata: 
      FormatName: image/png
      ImageWidth: 753
      ImageHeight: 493
      ColorSpace: CMYK
      BitsPerSample: 8
      BitsPerSampleUnit: integer
     Filter: FlateDecode
   Fonts: 
    Type1: 
     Font: 
      BaseFont: EKNIEB+AdvTT6780a46b+20
      FontSubset: true
      FirstChar: 146
      LastChar: 150
      FontDescriptor: 
       FontName: EKNIEB+AdvTT6780a46b+20
       Flags: Nonsymbolic
       FontBBox: 0, -114, 1156, 750
       FontFile3: true
      Encoding: WinAnsiEncoding
     Font: 
      BaseFont: EKNIDP+AdvOT919a0533.B
      FontSubset: true
      FirstChar: 46
      LastChar: 108
      FontDescriptor: 
       FontName: EKNIDP+AdvOT919a0533.B
       Flags: Nonsymbolic
       FontBBox: -31, -250, 656, 875
       FontFile3: true
      Encoding: WinAnsiEncoding
     Font: 
      BaseFont: EKNHNA+ArialMT
      FontSubset: true
      FirstChar: 2
      LastChar: 181
      FontDescriptor: 
       FontName: EKNHNA+ArialMT
       Flags: Symbolic
       FontBBox: -665, -325, 2000, 1040
       FontFile3: true
      EncodingDictionary: 
       Differences: true
      ToUnicode: true
     Font: 
      BaseFont: EKNIAP+Arial-ItalicMT
      FontSubset: true
      FirstChar: 32
      LastChar: 121
      FontDescriptor: 
       FontName: EKNIAP+Arial-ItalicMT
       Flags: Nonsymbolic, Italic
       FontBBox: -517, -325, 1359, 998
       FontFile3: true
      Encoding: WinAnsiEncoding
     Font: 
      BaseFont: EKNIEA+AdvTT6780a46b+fb
      FontSubset: true
      FirstChar: 1
      LastChar: 3
      FontDescriptor: 
       FontName: EKNIEA+AdvTT6780a46b+fb
       Flags: Symbolic
       FontBBox: 9, 0, 875, 750
       FontFile3: true
      EncodingDictionary: 
       Differences: true
      ToUnicode: true
     Font: 
      BaseFont: EKNFHP+AdvTT5afe5d37.B
      FontSubset: true
      FirstChar: 65
      LastChar: 84
      FontDescriptor: 
       FontName: EKNFHP+AdvTT5afe5d37.B
       Flags: Nonsymbolic
       FontBBox: -31, -250, 895, 864
       FontFile3: true
      Encoding: WinAnsiEncoding
     Font: 
      BaseFont: EKNFJP+Arial-BoldMT
      FontSubset: true
      FirstChar: 32
      LastChar: 181
      FontDescriptor: 
       FontName: EKNFJP+Arial-BoldMT
       Flags: Nonsymbolic
       FontBBox: -628, -376, 2000, 1010
       FontFile3: true
      Encoding: WinAnsiEncoding
     Font: 
      BaseFont: EKNJIK+AdvOT8608a8d1+03
      FontSubset: true
      FirstChar: 1
      LastChar: 3
      FontDescriptor: 
       FontName: EKNJIK+AdvOT8608a8d1+03
       Flags: Symbolic
       FontBBox: -479, -364, 854, 927
       FontFile3: true
      EncodingDictionary: 
       Differences: true
      ToUnicode: true
     Font: 
      BaseFont: EKNFLP+AdvOT46dcae81
      FontSubset: true
      FirstChar: 35
      LastChar: 252
      FontDescriptor: 
       FontName: EKNFLP+AdvOT46dcae81
       Flags: Nonsymbolic
       FontBBox: -41, -250, 833, 875
       FontFile3: true
      Encoding: WinAnsiEncoding
     Font: 
      BaseFont: EKNFMA+AdvTT6780a46b
      FontSubset: true
      FirstChar: 40
      LastChar: 246
      FontDescriptor: 
       FontName: EKNFMA+AdvTT6780a46b
       Flags: Nonsymbolic
       FontBBox: -41, -250, 875, 843
       FontFile3: true
      Encoding: WinAnsiEncoding
     Font: 
      BaseFont: EKNLBC+AdvOT46dcae81+03
      FontSubset: true
      FirstChar: 1
      LastChar: 5
      FontDescriptor: 
       FontName: EKNLBC+AdvOT46dcae81+03
       Flags: Symbolic
       FontBBox: -31, -208, 739, 802
       FontFile3: true
      EncodingDictionary: 
       Differences: true
      ToUnicode: true
     Font: 
      BaseFont: Arial-BoldItalicMT
      FirstChar: 0
      LastChar: 255
      FontDescriptor: 
       FontName: Arial-BoldItalicMT
       Flags: Nonsymbolic, Italic
       FontBBox: -560, -376, 1390, 1018
       FontFile3: true
      Encoding: WinAnsiEncoding
     Font: 
      BaseFont: EKNPJI+AdvTTab7e17fd+22
      FontSubset: true
      FirstChar: 2
      LastChar: 21
      FontDescriptor: 
       FontName: EKNPJI+AdvTTab7e17fd+22
       Flags: Symbolic
       FontBBox: -156, -218, 937, 947
       FontFile3: true
      EncodingDictionary: 
       Differences: true
      ToUnicode: true
     Font: 
      BaseFont: Calibri
      FirstChar: 0
      LastChar: 255
      FontDescriptor: 
       FontName: Calibri
       Flags: Nonsymbolic
       FontBBox: -503, -312, 1240, 1026
       FontFile3: true
      Encoding: WinAnsiEncoding
     Font: 
      BaseFont: EKNGNA+AdvOT3b30f6db.B
      FontSubset: true
      FirstChar: 45
      LastChar: 121
      FontDescriptor: 
       FontName: EKNGNA+AdvOT3b30f6db.B
       Flags: Nonsymbolic
       FontBBox: -31, -250, 875, 895
       FontFile3: true
      Encoding: WinAnsiEncoding
     Font: 
      BaseFont: EKNGNB+AdvOT46dcae81+20
      FontSubset: true
      FirstChar: 2
      LastChar: 150
      FontDescriptor: 
       FontName: EKNGNB+AdvOT46dcae81+20
       Flags: Symbolic
       FontBBox: 0, -197, 1125, 864
       FontFile3: true
      EncodingDictionary: 
       Differences: true
      ToUnicode: true
     Font: 
      BaseFont: EKNGLL+AdvTT2876772e+27
      FontSubset: true
      FirstChar: 1
      LastChar: 1
      FontDescriptor: 
       FontName: EKNGLL+AdvTT2876772e+27
       Flags: Symbolic
       FontBBox: 0, -197, 968, 770
       FontFile3: true
      EncodingDictionary: 
       Differences: true
      ToUnicode: true
     Font: 
      BaseFont: EKNGMM+AdvOT65f8a23b.I
      FontSubset: true
      FirstChar: 46
      LastChar: 121
      FontDescriptor: 
       FontName: EKNGMM+AdvOT65f8a23b.I
       Flags: Nonsymbolic
       FontBBox: -104, -250, 885, 864
       FontFile3: true
      Encoding: WinAnsiEncoding
     Font: 
      BaseFont: EKNGMN+AdvOT46dcae81+fb
      FontSubset: true
      FirstChar: 1
      LastChar: 3
      FontDescriptor: 
       FontName: EKNGMN+AdvOT46dcae81+fb
       Flags: Symbolic
       FontBBox: 0, 0, 739, 718
       FontFile3: true
      EncodingDictionary: 
       Differences: true
      ToUnicode: true
     Font: 
      BaseFont: EKNGMO+AdvMyriad_I
      FontSubset: true
      FirstChar: 79
      LastChar: 111
      FontDescriptor: 
       FontName: EKNGMO+AdvMyriad_I
       Flags: Nonsymbolic
       FontBBox: -104, -239, 1083, 750
       FontFile3: true
      Encoding: WinAnsiEncoding
     Font: 
      BaseFont: EKNGMP+AdvMyriad_R
      FontSubset: true
      FirstChar: 40
      LastChar: 150
      FontDescriptor: 
       FontName: EKNGMP+AdvMyriad_R
       Flags: Nonsymbolic
       FontBBox: -41, -239, 1125, 750
       FontFile3: true
      Encoding: WinAnsiEncoding
     Font: 
      BaseFont: EKOECO+AdvOT3b30f6db.B+20
      FontSubset: true
      FirstChar: 146
      LastChar: 146
      FontDescriptor: 
       FontName: EKOECO+AdvOT3b30f6db.B+20
       Flags: Nonsymbolic
       FontBBox: -10, -197, 1250, 864
       FontFile3: true
      Encoding: WinAnsiEncoding
     Font: 
      BaseFont: EKNHBD+AdvOT7d2ebc01
      FontSubset: true
      FirstChar: 48
      LastChar: 57
      FontDescriptor: 
       FontName: EKNHBD+AdvOT7d2ebc01
       Flags: Nonsymbolic
       FontBBox: -31, -208, 958, 916
       FontFile3: true
      Encoding: WinAnsiEncoding
     Font: 
      BaseFont: EKNGOB+AdvOTa20b42a7
      FontSubset: true
      FirstChar: 48
      LastChar: 121
      FontDescriptor: 
       FontName: EKNGOB+AdvOTa20b42a7
       Flags: Serif, Nonsymbolic
       FontBBox: -72, -239, 979, 906
       FontFile3: true
      Encoding: WinAnsiEncoding
     Font: 
      BaseFont: EKNHBB+AdvTTab7e17fd
      FontSubset: true
      FirstChar: 43
      LastChar: 61
      FontDescriptor: 
       FontName: EKNHBB+AdvTTab7e17fd
       Flags: Nonsymbolic
       FontBBox: -156, -250, 1072, 947
       FontFile3: true
      Encoding: WinAnsiEncoding
     Font: 
      BaseFont: EKNHBC+AdvOT3b30f6db.B+fb
      FontSubset: true
      FirstChar: 1
      LastChar: 1
      FontDescriptor: 
       FontName: EKNHBC+AdvOT3b30f6db.B+fb
       Flags: Symbolic
       FontBBox: 0, 0, 833, 718
       FontFile3: true
      EncodingDictionary: 
       Differences: true
      ToUnicode: true
   XMP: <x:xmpmeta xmlns:x="adobe:ns:meta/" x:xmptk="Adobe XMP Core 5.2-c001 63.143651, 2012/04/05-09:01:49        ">
   <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#">
      <rdf:Description rdf:about=""
            xmlns:dc="http://purl.org/dc/elements/1.1/">
         <dc:format>application/pdf</dc:format>
         <dc:identifier>doi:10.1038/s41388-022-02450-3</dc:identifier>
         <dc:title>
            <rdf:Alt>
               <rdf:li xml:lang="x-default">Targeting the MYC interaction network in B-cell lymphoma via histone deacetylase 6 inhibition</rdf:li>
            </rdf:Alt>
         </dc:title>
         <dc:creator>
            <rdf:Seq>
               <rdf:li>René Winkler</rdf:li>
               <rdf:li>Ann-Sophie Mägdefrau</rdf:li>
               <rdf:li>Eva-Maria Piskor</rdf:li>
               <rdf:li>Markus Kleemann</rdf:li>
               <rdf:li>Mandy Beyer</rdf:li>
               <rdf:li>Kevin Linke</rdf:li>
               <rdf:li>Lisa Hansen</rdf:li>
               <rdf:li>Anna-Maria Schaffer</rdf:li>
               <rdf:li>Marina E. Hoffmann</rdf:li>
               <rdf:li>Simon Poepsel</rdf:li>
               <rdf:li>Florian Heyd</rdf:li>
               <rdf:li>Petra Beli</rdf:li>
               <rdf:li>Tarik Möröy</rdf:li>
               <rdf:li>Siavosh Mahboobi</rdf:li>
               <rdf:li>Oliver H. Krämer</rdf:li>
               <rdf:li>Christian Kosan</rdf:li>
            </rdf:Seq>
         </dc:creator>
         <dc:publisher>
            <rdf:Bag>
               <rdf:li>Springer US</rdf:li>
            </rdf:Bag>
         </dc:publisher>
         <dc:subject>
            <rdf:Bag/>
         </dc:subject>
         <dc:description>
            <rdf:Alt>
               <rdf:li xml:lang="x-default">Oncogene, doi:10.1038/s41388-022-02450-3</rdf:li>
            </rdf:Alt>
         </dc:description>
      </rdf:Description>
      <rdf:Description rdf:about=""
            xmlns:xmp="http://ns.adobe.com/xap/1.0/">
         <xmp:CreatorTool>Springer</xmp:CreatorTool>
         <xmp:ModifyDate>2022-09-24T14:04:02+05:30</xmp:ModifyDate>
         <xmp:CreateDate>2022-09-24T14:03:34+05:30</xmp:CreateDate>
         <xmp:MetadataDate>2022-09-24T14:04:02+05:30</xmp:MetadataDate>
      </rdf:Description>
      <rdf:Description rdf:about=""
            xmlns:xmpRights="http://ns.adobe.com/xap/1.0/rights/">
         <xmpRights:Marked>True</xmpRights:Marked>
      </rdf:Description>
      <rdf:Description rdf:about=""
            xmlns:pdf="http://ns.adobe.com/pdf/1.3/">
         <pdf:Keywords/>
      </rdf:Description>
      <rdf:Description rdf:about=""
            xmlns:xmpMM="http://ns.adobe.com/xap/1.0/mm/"
            xmlns:stEvt="http://ns.adobe.com/xap/1.0/sType/ResourceEvent#">
         <xmpMM:DocumentID>uuid:d12385a5-8866-4a7c-b7d2-f058b46ba3a2</xmpMM:DocumentID>
         <xmpMM:InstanceID>uuid:0a1ee37f-7214-4910-92a5-1e2e6c56bc6c</xmpMM:InstanceID>
         <xmpMM:RenditionClass>default</xmpMM:RenditionClass>
         <xmpMM:VersionID>1</xmpMM:VersionID>
         <xmpMM:History>
            <rdf:Seq>
               <rdf:li rdf:parseType="Resource">
                  <stEvt:action>converted</stEvt:action>
                  <stEvt:instanceID>uuid:462e9f5f-e424-4614-a0b2-6a43606fe6f3</stEvt:instanceID>
                  <stEvt:parameters>converted to PDF/A-2b</stEvt:parameters>
                  <stEvt:softwareAgent>pdfToolbox</stEvt:softwareAgent>
                  <stEvt:when>2022-09-24T14:04:02+05:30</stEvt:when>
               </rdf:li>
            </rdf:Seq>
         </xmpMM:History>
      </rdf:Description>
      <rdf:Description rdf:about=""
            xmlns:pdfaid="http://www.aiim.org/pdfa/ns/id/">
         <pdfaid:part>2</pdfaid:part>
         <pdfaid:conformance>B</pdfaid:conformance>
      </rdf:Description>
      <rdf:Description rdf:about=""
            xmlns:pdfaExtension="http://www.aiim.org/pdfa/ns/extension/"
            xmlns:pdfaSchema="http://www.aiim.org/pdfa/ns/schema#"
            xmlns:pdfaProperty="http://www.aiim.org/pdfa/ns/property#">
         <pdfaExtension:schemas>
            <rdf:Bag>
               <rdf:li rdf:parseType="Resource">
                  <pdfaSchema:namespaceURI>http://ns.adobe.com/pdf/1.3/</pdfaSchema:namespaceURI>
                  <pdfaSchema:prefix>pdf</pdfaSchema:prefix>
                  <pdfaSchema:schema>Adobe PDF Schema</pdfaSchema:schema>
                  <pdfaSchema:property>
                     <rdf:Seq>
                        <rdf:li rdf:parseType="Resource">
                           <pdfaProperty:category>internal</pdfaProperty:category>
                           <pdfaProperty:description>A name object indicating whether the document has been modified to include trapping information</pdfaProperty:description>
                           <pdfaProperty:name>Trapped</pdfaProperty:name>
                           <pdfaProperty:valueType>Text</pdfaProperty:valueType>
                        </rdf:li>
                     </rdf:Seq>
                  </pdfaSchema:property>
               </rdf:li>
               <rdf:li rdf:parseType="Resource">
                  <pdfaSchema:namespaceURI>http://ns.adobe.com/pdfx/1.3/</pdfaSchema:namespaceURI>
                  <pdfaSchema:prefix>pdfx</pdfaSchema:prefix>
                  <pdfaSchema:schema>Adobe Document Info PDF eXtension Schema</pdfaSchema:schema>
                  <pdfaSchema:property>
                     <rdf:Seq>
                        <rdf:li rdf:parseType="Resource">
                           <pdfaProperty:category>internal</pdfaProperty:category>
                           <pdfaProperty:description>ID of PDF/X standard</pdfaProperty:description>
                           <pdfaProperty:name>GTS_PDFXVersion</pdfaProperty:name>
                           <pdfaProperty:valueType>Text</pdfaProperty:valueType>
                        </rdf:li>
                        <rdf:li rdf:parseType="Resource">
                           <pdfaProperty:category>internal</pdfaProperty:category>
                           <pdfaProperty:description>Conformance level of PDF/X standard</pdfaProperty:description>
                           <pdfaProperty:name>GTS_PDFXConformance</pdfaProperty:name>
                           <pdfaProperty:valueType>Text</pdfaProperty:valueType>
                        </rdf:li>
                        <rdf:li rdf:parseType="Resource">
                           <pdfaProperty:category>internal</pdfaProperty:category>
                           <pdfaProperty:description>Company creating the PDF</pdfaProperty:description>
                           <pdfaProperty:name>Company</pdfaProperty:name>
                           <pdfaProperty:valueType>Text</pdfaProperty:valueType>
                        </rdf:li>
                        <rdf:li rdf:parseType="Resource">
                           <pdfaProperty:category>internal</pdfaProperty:category>
                           <pdfaProperty:description>Date when document was last modified</pdfaProperty:description>
                           <pdfaProperty:name>SourceModified</pdfaProperty:name>
                           <pdfaProperty:valueType>Text</pdfaProperty:valueType>
                        </rdf:li>
                     </rdf:Seq>
                  </pdfaSchema:property>
               </rdf:li>
               <rdf:li rdf:parseType="Resource">
                  <pdfaSchema:namespaceURI>http://ns.adobe.com/xap/1.0/mm/</pdfaSchema:namespaceURI>
                  <pdfaSchema:prefix>xmpMM</pdfaSchema:prefix>
                  <pdfaSchema:schema>XMP Media Management Schema</pdfaSchema:schema>
                  <pdfaSchema:property>
                     <rdf:Seq>
                        <rdf:li rdf:parseType="Resource">
                           <pdfaProperty:category>internal</pdfaProperty:category>
                           <pdfaProperty:description>UUID based identifier for specific incarnation of a document</pdfaProperty:description>
                           <pdfaProperty:name>InstanceID</pdfaProperty:name>
                           <pdfaProperty:valueType>URI</pdfaProperty:valueType>
                        </rdf:li>
                        <rdf:li rdf:parseType="Resource">
                           <pdfaProperty:category>internal</pdfaProperty:category>
                           <pdfaProperty:description>The common identifier for all versions and renditions of a document.</pdfaProperty:description>
                           <pdfaProperty:name>OriginalDocumentID</pdfaProperty:name>
                           <pdfaProperty:valueType>URI</pdfaProperty:valueType>
                        </rdf:li>
                     </rdf:Seq>
                  </pdfaSchema:property>
               </rdf:li>
               <rdf:li rdf:parseType="Resource">
                  <pdfaSchema:namespaceURI>http://www.aiim.org/pdfa/ns/id/</pdfaSchema:namespaceURI>
                  <pdfaSchema:prefix>pdfaid</pdfaSchema:prefix>
                  <pdfaSchema:schema>PDF/A ID Schema</pdfaSchema:schema>
                  <pdfaSchema:property>
                     <rdf:Seq>
                        <rdf:li rdf:parseType="Resource">
                           <pdfaProperty:category>internal</pdfaProperty:category>
                           <pdfaProperty:description>Part of PDF/A standard</pdfaProperty:description>
                           <pdfaProperty:name>part</pdfaProperty:name>
                           <pdfaProperty:valueType>Integer</pdfaProperty:valueType>
                        </rdf:li>
                        <rdf:li rdf:parseType="Resource">
                           <pdfaProperty:category>internal</pdfaProperty:category>
                           <pdfaProperty:description>Amendment of PDF/A standard</pdfaProperty:description>
                           <pdfaProperty:name>amd</pdfaProperty:name>
                           <pdfaProperty:valueType>Text</pdfaProperty:valueType>
                        </rdf:li>
                        <rdf:li rdf:parseType="Resource">
                           <pdfaProperty:category>internal</pdfaProperty:category>
                           <pdfaProperty:description>Conformance level of PDF/A standard</pdfaProperty:description>
                           <pdfaProperty:name>conformance</pdfaProperty:name>
                           <pdfaProperty:valueType>Text</pdfaProperty:valueType>
                        </rdf:li>
                     </rdf:Seq>
                  </pdfaSchema:property>
               </rdf:li>
            </rdf:Bag>
         </pdfaExtension:schemas>
      </rdf:Description>
   </rdf:RDF>
</x:xmpmeta>
   Pages: 
    Page: 
     Label: 4560
     Sequence: 1
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 487, 689, 489, 721
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 487, 695, 543, 727
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 543, 695, 559, 705
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 543, 695, 559, 705
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 208, 628, 209, 637
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 208, 628, 209, 637
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 218, 628, 220, 637
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 211, 628, 218, 637
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 218, 628, 218, 637
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 298, 628, 299, 637
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 298, 628, 299, 637
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 308, 628, 311, 637
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 301, 628, 308, 637
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 308, 628, 308, 637
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 386, 628, 387, 637
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 386, 628, 387, 637
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 396, 628, 399, 637
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 389, 628, 396, 637
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 396, 628, 396, 637
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 509, 628, 510, 637
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 509, 628, 510, 637
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 519, 628, 521, 637
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 511, 628, 519, 637
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 519, 628, 519, 637
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 178, 617, 179, 626
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 178, 617, 179, 626
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 188, 617, 190, 626
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 181, 617, 188, 626
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 188, 617, 188, 626
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 274, 617, 275, 626
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 274, 617, 275, 626
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 284, 617, 286, 626
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 277, 617, 284, 626
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 284, 617, 284, 626
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 350, 617, 351, 626
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 350, 617, 351, 626
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 360, 617, 362, 626
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 353, 617, 360, 626
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 360, 617, 360, 626
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 468, 617, 469, 626
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 468, 617, 469, 626
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 477, 617, 480, 626
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 470, 617, 477, 626
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 477, 617, 478, 626
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 189, 606, 190, 615
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 189, 606, 190, 615
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 199, 606, 201, 615
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 192, 606, 199, 615
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 199, 606, 199, 615
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 284, 606, 285, 615
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 284, 606, 285, 615
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 294, 606, 296, 615
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 286, 606, 294, 615
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 294, 606, 294, 615
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 180, 408, 345, 417
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 113, 320, 118, 329
       Flags: Print
       AppearanceDictionary: true
       Destination: 222
      Annotation: 
       Subtype: Link
       Rect: 100, 290, 105, 299
       Flags: Print
       AppearanceDictionary: true
       Destination: 222
      Annotation: 
       Subtype: Link
       Rect: 76, 270, 80, 279
       Flags: Print
       AppearanceDictionary: true
       Destination: 222
      Annotation: 
       Subtype: Link
       Rect: 187, 261, 192, 269
       Flags: Print
       AppearanceDictionary: true
       Destination: 222
      Annotation: 
       Subtype: Link
       Rect: 227, 251, 231, 259
       Flags: Print
       AppearanceDictionary: true
       Destination: 222
      Annotation: 
       Subtype: Link
       Rect: 91, 231, 96, 240
       Flags: Print
       AppearanceDictionary: true
       Destination: 222
      Annotation: 
       Subtype: Link
       Rect: 101, 231, 105, 240
       Flags: Print
       AppearanceDictionary: true
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 142, 211, 146, 220
       Flags: Print
       AppearanceDictionary: true
       Destination: 222
      Annotation: 
       Subtype: Link
       Rect: 151, 211, 156, 220
       Flags: Print
       AppearanceDictionary: true
       Destination: 222
      Annotation: 
       Subtype: Link
       Rect: 47, 191, 52, 200
       Flags: Print
       AppearanceDictionary: true
       Destination: 222
      Annotation: 
       Subtype: Link
       Rect: 57, 191, 61, 200
       Flags: Print
       AppearanceDictionary: true
       Destination: 222
      Annotation: 
       Subtype: Link
       Rect: 105, 171, 110, 180
       Flags: Print
       AppearanceDictionary: true
       Destination: 222
      Annotation: 
       Subtype: Link
       Rect: 187, 161, 196, 170
       Flags: Print
       AppearanceDictionary: true
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 412, 350, 421, 359
       Flags: Print
       AppearanceDictionary: true
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 342, 320, 352, 329
       Flags: Print
       AppearanceDictionary: true
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 335, 251, 339, 259
       Flags: Print
       AppearanceDictionary: true
       Destination: 222
      Annotation: 
       Subtype: Link
       Rect: 366, 231, 375, 240
       Flags: Print
       AppearanceDictionary: true
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 380, 231, 389, 240
       Flags: Print
       AppearanceDictionary: true
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 473, 201, 482, 210
       Flags: Print
       AppearanceDictionary: true
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 373, 171, 383, 180
       Flags: Print
       AppearanceDictionary: true
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 269, 80, 350, 87
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 45, 749, 120, 757
       Flags: Print
       AppearanceDictionary: true
     Thumb: true
    Page: 
     Label: 4561
     Sequence: 2
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 270, 723, 279, 732
       Flags: Print
       AppearanceDictionary: true
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 90, 693, 99, 702
       Flags: Print
       AppearanceDictionary: true
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 85, 623, 95, 632
       Flags: Print
       AppearanceDictionary: true
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 128, 603, 137, 612
       Flags: Print
       AppearanceDictionary: true
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 38, 573, 47, 582
       Flags: Print
       AppearanceDictionary: true
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 51, 573, 60, 582
       Flags: Print
       AppearanceDictionary: true
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 255, 563, 264, 572
       Flags: Print
       AppearanceDictionary: true
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 270, 563, 279, 572
       Flags: Print
       AppearanceDictionary: true
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 143, 534, 153, 543
       Flags: Print
       AppearanceDictionary: true
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 159, 534, 168, 543
       Flags: Print
       AppearanceDictionary: true
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 216, 514, 225, 523
       Flags: Print
       AppearanceDictionary: true
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 150, 334, 159, 343
       Flags: Print
       AppearanceDictionary: true
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 95, 294, 99, 303
       Flags: Print
       AppearanceDictionary: true
       Destination: 47
      Annotation: 
       Subtype: Link
       Rect: 57, 275, 61, 284
       Flags: Print
       AppearanceDictionary: true
       Destination: 47
      Annotation: 
       Subtype: Link
       Rect: 177, 265, 186, 274
       Flags: Print
       AppearanceDictionary: true
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 192, 265, 202, 274
       Flags: Print
       AppearanceDictionary: true
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 239, 235, 244, 244
       Flags: Print
       AppearanceDictionary: true
       Destination: 47
      Annotation: 
       Subtype: Link
       Rect: 104, 215, 113, 224
       Flags: Print
       AppearanceDictionary: true
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 270, 195, 279, 204
       Flags: Print
       AppearanceDictionary: true
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 244, 175, 249, 184
       Flags: Print
       AppearanceDictionary: true
       Destination: 47
      Annotation: 
       Subtype: Link
       Rect: 184, 125, 194, 134
       Flags: Print
       AppearanceDictionary: true
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 144, 65, 148, 74
       Flags: Print
       AppearanceDictionary: true
       Destination: 47
      Annotation: 
       Subtype: Link
       Rect: 459, 683, 464, 692
       Flags: Print
       AppearanceDictionary: true
       Destination: 47
      Annotation: 
       Subtype: Link
       Rect: 304, 673, 313, 682
       Flags: Print
       AppearanceDictionary: true
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 322, 633, 327, 642
       Flags: Print
       AppearanceDictionary: true
       Destination: 47
      Annotation: 
       Subtype: Link
       Rect: 321, 603, 325, 612
       Flags: Print
       AppearanceDictionary: true
       Destination: 47
      Annotation: 
       Subtype: Link
       Rect: 304, 544, 313, 552
       Flags: Print
       AppearanceDictionary: true
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 320, 544, 329, 552
       Flags: Print
       AppearanceDictionary: true
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 346, 514, 351, 523
       Flags: Print
       AppearanceDictionary: true
       Destination: 47
      Annotation: 
       Subtype: Link
       Rect: 431, 374, 435, 383
       Flags: Print
       AppearanceDictionary: true
       Destination: 47
      Annotation: 
       Subtype: Link
       Rect: 523, 255, 527, 264
       Flags: Print
       AppearanceDictionary: true
       Destination: 69
      Annotation: 
       Subtype: Link
       Rect: 417, 235, 421, 244
       Flags: Print
       AppearanceDictionary: true
       Destination: 69
      Annotation: 
       Subtype: Link
       Rect: 321, 185, 326, 194
       Flags: Print
       AppearanceDictionary: true
       Destination: 69
      Annotation: 
       Subtype: Link
       Rect: 405, 175, 410, 184
       Flags: Print
       AppearanceDictionary: true
       Destination: 69
      Annotation: 
       Subtype: Link
       Rect: 325, 145, 330, 154
       Flags: Print
       AppearanceDictionary: true
       Destination: 69
      Annotation: 
       Subtype: Link
       Rect: 534, 135, 539, 144
       Flags: Print
       AppearanceDictionary: true
       Destination: 69
      Annotation: 
       Subtype: Link
       Rect: 497, 125, 501, 134
       Flags: Print
       AppearanceDictionary: true
       Destination: 69
      Annotation: 
       Subtype: Link
       Rect: 523, 105, 528, 114
       Flags: Print
       AppearanceDictionary: true
       Destination: 69
      Annotation: 
       Subtype: Link
       Rect: 442, 65, 447, 74
       Flags: Print
       AppearanceDictionary: true
       Destination: 69
     Thumb: true
    Page: 
     Label: 4562
     Sequence: 3
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 279, 167, 284, 176
       Flags: Print
       AppearanceDictionary: true
       Destination: 69
      Annotation: 
       Subtype: Link
       Rect: 63, 127, 68, 136
       Flags: Print
       AppearanceDictionary: true
       Destination: 69
      Annotation: 
       Subtype: Link
       Rect: 251, 117, 260, 126
       Flags: Print
       AppearanceDictionary: true
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 64, 87, 69, 96
       Flags: Print
       AppearanceDictionary: true
       Destination: 69
      Annotation: 
       Subtype: Link
       Rect: 451, 127, 460, 136
       Flags: Print
       AppearanceDictionary: true
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 464, 127, 473, 136
       Flags: Print
       AppearanceDictionary: true
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 531, 117, 541, 126
       Flags: Print
       AppearanceDictionary: true
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 545, 117, 555, 126
       Flags: Print
       AppearanceDictionary: true
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 336, 107, 341, 116
       Flags: Print
       AppearanceDictionary: true
       Destination: 83
      Annotation: 
       Subtype: Link
       Rect: 355, 87, 359, 96
       Flags: Print
       AppearanceDictionary: true
       Destination: 135
     Thumb: true
    Page: 
     Label: 4563
     Sequence: 4
     Thumb: true
    Page: 
     Label: 4564
     Sequence: 5
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 142, 553, 146, 562
       Flags: Print
       AppearanceDictionary: true
       Destination: 135
      Annotation: 
       Subtype: Link
       Rect: 279, 533, 284, 542
       Flags: Print
       AppearanceDictionary: true
       Destination: 135
      Annotation: 
       Subtype: Link
       Rect: 103, 503, 107, 512
       Flags: Print
       AppearanceDictionary: true
       Destination: 135
      Annotation: 
       Subtype: Link
       Rect: 83, 463, 88, 472
       Flags: Print
       AppearanceDictionary: true
       Destination: 135
      Annotation: 
       Subtype: Link
       Rect: 119, 463, 124, 472
       Flags: Print
       AppearanceDictionary: true
       Destination: 83
      Annotation: 
       Subtype: Link
       Rect: 215, 354, 220, 363
       Flags: Print
       AppearanceDictionary: true
       Destination: 135
      Annotation: 
       Subtype: Link
       Rect: 279, 334, 283, 343
       Flags: Print
       AppearanceDictionary: true
       Destination: 135
      Annotation: 
       Subtype: Link
       Rect: 209, 264, 214, 273
       Flags: Print
       AppearanceDictionary: true
       Destination: 135
      Annotation: 
       Subtype: Link
       Rect: 227, 234, 232, 243
       Flags: Print
       AppearanceDictionary: true
       Destination: 135
      Annotation: 
       Subtype: Link
       Rect: 65, 194, 69, 203
       Flags: Print
       AppearanceDictionary: true
       Destination: 135
      Annotation: 
       Subtype: Link
       Rect: 225, 174, 230, 183
       Flags: Print
       AppearanceDictionary: true
       Destination: 135
      Annotation: 
       Subtype: Link
       Rect: 121, 144, 130, 153
       Flags: Print
       AppearanceDictionary: true
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 131, 65, 135, 74
       Flags: Print
       AppearanceDictionary: true
       Destination: 171
      Annotation: 
       Subtype: Link
       Rect: 331, 703, 335, 712
       Flags: Print
       AppearanceDictionary: true
       Destination: 171
      Annotation: 
       Subtype: Link
       Rect: 488, 683, 493, 692
       Flags: Print
       AppearanceDictionary: true
       Destination: 171
      Annotation: 
       Subtype: Link
       Rect: 452, 603, 456, 612
       Flags: Print
       AppearanceDictionary: true
       Destination: 171
      Annotation: 
       Subtype: Link
       Rect: 499, 573, 504, 582
       Flags: Print
       AppearanceDictionary: true
       Destination: 171
      Annotation: 
       Subtype: Link
       Rect: 381, 544, 386, 552
       Flags: Print
       AppearanceDictionary: true
       Destination: 171
      Annotation: 
       Subtype: Link
       Rect: 377, 524, 382, 533
       Flags: Print
       AppearanceDictionary: true
       Destination: 171
      Annotation: 
       Subtype: Link
       Rect: 521, 414, 526, 423
       Flags: Print
       AppearanceDictionary: true
       Destination: 187
      Annotation: 
       Subtype: Link
       Rect: 524, 384, 529, 393
       Flags: Print
       AppearanceDictionary: true
       Destination: 187
      Annotation: 
       Subtype: Link
       Rect: 438, 344, 443, 353
       Flags: Print
       AppearanceDictionary: true
       Destination: 187
      Annotation: 
       Subtype: Link
       Rect: 454, 304, 458, 313
       Flags: Print
       AppearanceDictionary: true
       Destination: 187
      Annotation: 
       Subtype: Link
       Rect: 362, 235, 366, 244
       Flags: Print
       AppearanceDictionary: true
       Destination: 187
      Annotation: 
       Subtype: Link
       Rect: 499, 225, 504, 234
       Flags: Print
       AppearanceDictionary: true
       Destination: 187
      Annotation: 
       Subtype: Link
       Rect: 520, 215, 524, 224
       Flags: Print
       AppearanceDictionary: true
       Destination: 222
      Annotation: 
       Subtype: Link
       Rect: 488, 105, 493, 114
       Flags: Print
       AppearanceDictionary: true
       Destination: 187
      Annotation: 
       Subtype: Link
       Rect: 450, 65, 455, 74
       Flags: Print
       AppearanceDictionary: true
       Destination: 187
     Thumb: true
    Page: 
     Label: 4565
     Sequence: 6
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 54, 95, 59, 104
       Flags: Print
       AppearanceDictionary: true
       Destination: 187
      Annotation: 
       Subtype: Link
       Rect: 242, 75, 251, 84
       Flags: Print
       AppearanceDictionary: true
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 432, 75, 437, 84
       Flags: Print
       AppearanceDictionary: true
       Destination: 222
      Annotation: 
       Subtype: Link
       Rect: 538, 56, 543, 65
       Flags: Print
       AppearanceDictionary: true
       Destination: 222
     Thumb: true
    Page: 
     Label: 4566
     Sequence: 7
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 122, 575, 131, 584
       Flags: Print
       AppearanceDictionary: true
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 137, 575, 146, 584
       Flags: Print
       AppearanceDictionary: true
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 113, 565, 117, 574
       Flags: Print
       AppearanceDictionary: true
       Destination: 222
      Annotation: 
       Subtype: Link
       Rect: 279, 555, 283, 564
       Flags: Print
       AppearanceDictionary: true
       Destination: 222
      Annotation: 
       Subtype: Link
       Rect: 147, 486, 156, 494
       Flags: Print
       AppearanceDictionary: true
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 261, 456, 266, 465
       Flags: Print
       AppearanceDictionary: true
       Destination: 222
      Annotation: 
       Subtype: Link
       Rect: 219, 416, 224, 425
       Flags: Print
       AppearanceDictionary: true
       Destination: 222
      Annotation: 
       Subtype: Link
       Rect: 218, 346, 222, 355
       Flags: Print
       AppearanceDictionary: true
       Destination: 222
      Annotation: 
       Subtype: Link
       Rect: 193, 266, 202, 275
       Flags: Print
       AppearanceDictionary: true
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 206, 266, 215, 275
       Flags: Print
       AppearanceDictionary: true
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 234, 157, 244, 166
       Flags: Print
       AppearanceDictionary: true
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 139, 147, 148, 156
       Flags: Print
       AppearanceDictionary: true
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 109, 117, 118, 126
       Flags: Print
       AppearanceDictionary: true
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 80, 87, 90, 96
       Flags: Print
       AppearanceDictionary: true
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 456, 555, 465, 564
       Flags: Print
       AppearanceDictionary: true
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 469, 555, 478, 564
       Flags: Print
       AppearanceDictionary: true
       Destination: 235
      Annotation: 
       Subtype: Link
       Rect: 392, 505, 401, 514
       Flags: Print
       AppearanceDictionary: true
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 390, 366, 399, 375
       Flags: Print
       AppearanceDictionary: true
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 313, 346, 322, 355
       Flags: Print
       AppearanceDictionary: true
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 327, 346, 336, 355
       Flags: Print
       AppearanceDictionary: true
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 341, 346, 350, 355
       Flags: Print
       AppearanceDictionary: true
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 525, 326, 529, 335
       Flags: Print
       AppearanceDictionary: true
       Destination: 222
      Annotation: 
       Subtype: Link
       Rect: 378, 266, 387, 275
       Flags: Print
       AppearanceDictionary: true
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 394, 266, 403, 275
       Flags: Print
       AppearanceDictionary: true
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 493, 256, 502, 265
       Flags: Print
       AppearanceDictionary: true
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 507, 197, 516, 206
       Flags: Print
       AppearanceDictionary: true
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 504, 187, 513, 196
       Flags: Print
       AppearanceDictionary: true
       Destination: null
     Thumb: true
    Page: 
     Label: 4567
     Sequence: 8
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 117, 74, 124, 82
       Flags: Print
       AppearanceDictionary: true
       Destination: null
     Thumb: true
    Page: 
     Label: 4568
     Sequence: 9
     Thumb: true
    Page: 
     Label: 4569
     Sequence: 10
     Thumb: true
    Page: 
     Label: 4570
     Sequence: 11
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 138, 524, 146, 532
       Flags: Print
       AppearanceDictionary: true
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 159, 391, 167, 399
       Flags: Print
       AppearanceDictionary: true
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 72, 373, 81, 381
       Flags: Print
       AppearanceDictionary: true
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 206, 328, 214, 336
       Flags: Print
       AppearanceDictionary: true
       Destination: null
     Thumb: true
    Page: 
     Label: 4571
     Sequence: 12
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 337, 146, 465, 153
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 479, 110, 549, 117
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 301, 101, 324, 108
       Flags: Print
       AppearanceDictionary: true
     Thumb: true
    Page: 
     Label: 4572
     Sequence: 13
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 275, 643, 293, 650
       Flags: Print
       AppearanceDictionary: true
      Annotation: 
       Subtype: Link
       Rect: 45, 634, 156, 641
       Flags: Print
       AppearanceDictionary: true
     Thumb: true
  Checksum: b9028d91
   Type: CRC32
  Checksum: e1b8248b7418235700ed1509b7b1e03b
   Type: MD5
  Checksum: 2a65274c6524d5e534d3d3571cea111a3b32d6dd
   Type: SHA-1