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Title:          Environmentally driven transcriptomic and metabolic changes leading to color differences in “Golden Reinders” apples
Subject:        Apple is characterized by its high adaptation to diverse growing environments.
Author:         Manuel Rodriguez-Concepcion
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     Item: 
      Title: Environmentally driven transcriptomic and metabolic changes leading to color differences in “Golden Reinders” apples
      Children: 
       Item: 
        Title: Introduction
       Item: 
        Title: Materials and methods
        Children: 
         Item: 
          Title: Plant material and experimental design
         Item: 
          Title: Fruit quality evaluation
         Item: 
          Title: RNA extraction and sequencing
         Item: 
          Title: cDNA and qPCR analysis
         Item: 
          Title: Photosynthetic pigments and tocopherols analysis
         Item: 
          Title: ABA quantification
         Item: 
          Title: Quantification of hydrogen peroxide and malondialdehyde
         Item: 
          Title: Ascorbic acid and dehydroascorbic acid content
         Item: 
          Title: Determination of phenolic compounds and the peel antioxidant capacity
         Item: 
          Title: Antioxidant enzymes activity
         Item: 
          Title: Statistical data analysis
       Item: 
        Title: Results
        Children: 
         Item: 
          Title: Orchard location influences peel color and composition
         Item: 
          Title: Transcriptome reprograming in response to orchard location
         Item: 
          Title: Pigment metabolism during fruit development is differentially affected by the environment
         Item: 
          Title: The levels of tocopherols and phenolic compounds are greater in mountain apples
         Item: 
          Title: The environment strongly influences ROS-scavenging enzymes in the apple peel
       Item: 
        Title: Discussion
        Children: 
         Item: 
          Title: Optimal yellow peel color in “Golden Reinders” apples is associated to oxidative stress
         Item: 
          Title: Pigments and phenolic compounds decrease during fruit development and ripening
         Item: 
          Title: The accumulation of H 2 O 2 favored by the mountain environment may trigger apple peel degreening
       Item: 
        Title: Conclusion
       Item: 
        Title: Data availability statement
       Item: 
        Title: Author contributions
       Item: 
        Title: Funding
       Item: 
        Title: Conflict of interest
       Item: 
        Title: Publisher’s note
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