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Actualización 2022 Subject: Open Respiratory Archives, Corrected proof. doi:10.1016/j.opresp.2022.100192 Keywords: Asma grave; Diagnóstico; Seguimiento; Tratamiento; Anticuerpos monoclonales Author: Francisco Javier Alvarez-Gutiérrez Creator: Elsevier Producer: Acrobat Distiller 11.0 (Windows) CreationDate: Wed Aug 10 14:13:24 2022 CEST ModDate: Thu Dec 22 10:52:26 2022 CET Tagged: yes UserProperties: no Suspects: no Form: none JavaScript: no Pages: 27 Encrypted: no Page size: 595.28 x 793.7 pts Page rot: 0 File size: 1347732 bytes Optimized: yes PDF version: 1.7 name type encoding emb sub uni object ID ------------------------------------ ----------------- ---------------- --- --- --- --------- KNOBLN+GulliverRM Type 1C Custom yes yes yes 1774 0 KNOHFB+GulliverBL Type 1C Custom yes yes yes 1777 0 KNOBMN+Times-Roman Type 1C WinAnsi yes yes no 1779 0 KNOBNO+DIN-CondensedBoldA Type 1C Custom yes yes yes 1782 0 KNOCEM+Univers Type 1C Custom yes yes yes 1785 0 KNOCNK+OnemtmiguAAAA Type 1C Custom yes yes yes 1788 0 KNOCOK+MTSY Type 1C Custom yes yes yes 1791 0 KNODDJ+Msam10 Type 1C Custom yes yes yes 1794 0 KNODDK+GulliverIT Type 1C Custom yes yes yes 1797 0 KNOFBP+GulliverSCOsF Type 1C Custom yes yes yes 1800 0 KNOPAA+OneGulliverA Type 1C Custom yes yes yes 1079 0 KNPCDM+MATHG-1A Type 1C Custom yes yes no 1076 0 KNPEIO+MarVoSym Type 1C Custom yes yes yes 1075 0 Jhove (Rel. 1.22.1, 2019-04-17) Date: 2023-06-09 02:29:35 CEST RepresentationInformation: 275165.pdf ReportingModule: PDF-hul, Rel. 1.12.1 (2019-04-17) LastModified: 2023-06-08 12:44:47 CEST Size: 1347732 Format: PDF Version: 1.7 Status: Well-Formed and valid SignatureMatches: PDF-hul MIMEtype: application/pdf Profile: Linearized PDF PDFMetadata: Objects: 0 FreeObjects: 1 IncrementalUpdates: 0 DocumentCatalog: PageLayout: SinglePage PageMode: UseOutlines Language: EN Outlines: Item: Title: Documento de consenso de asma grave en adultos. Actualización 2022 Destination: 1 Children: Item: Title: Metodología Destination: 1 Item: Title: Diagnóstico del asma grave Destination: 1 Children: Item: Title: Definición Destination: 1 Item: Title: Según el grupo de panelistas Destination: 1 Item: Title: Epidemiología Destination: 1 Item: Title: Abordaje diagnóstico estructurado/escalonado Destination: 1 Item: Title: De esta manera, según el panel de expertos: Destination: 1 Item: Title: Fenotipos de asma grave Destination: 1 Item: Title: Seguimiento del asma grave Destination: 1 Children: Item: Title: Introducción Destination: 1 Item: Title: Indicadores de la situación del paciente Destination: 1 Item: Title: Indicadores de cumplimiento del tratamiento Destination: 1 Item: Title: Indicadores para establecer el pronóstico Destination: 1 Item: Title: Marcadores de planificación del ajuste terapéutico Destination: 1 Item: Title: Consulta de enfermería respiratoria Destination: 1 Item: Title: Tratamiento del asma grave Destination: 1 Children: Item: Title: Introducción Destination: 1 Item: Title: Tratamiento farmacológico de base Destination: 1 Item: Title: Tratamiento de las comorbilidades Destination: 1 Item: Title: Manejo de los glucocorticoides sistémicos. Evaluación indicaciones, efectos secundarios y pauta de reducción Destination: 1 Item: Title: Otros tratamientos para el asma grave Destination: 1 Children: Item: Title: Macrólidos Destination: 1 Item: Title: Termoplastia Destination: 1 Item: Title: Anticuerpos monoclonales disponibles actualmente Destination: 1 Children: Item: Title: Omalizumab Destination: 1 Item: Title: Mepolizumab Destination: 1 Item: Title: Reslizumab Destination: 1 Item: Title: Benralizumab Destination: 1 Item: Title: Dupilumab Destination: 1 Item: Title: Cambio de anticuerpo monoclonal en pacientes poco o no respondedores a un anticuerpo determinado. Destination: 1 Item: Title: Otros anticuerpos monoclonales en fases avanzadas de investigación Destination: 1 Children: Item: Title: Tezepelumab Destination: 1 Item: Title: Medidas preventivas en asma Destination: 1 Children: Item: Title: Medidas de control ambiental Destination: 1 Item: Title: Evitar el tabaquismo activo y pasivo Destination: 1 Item: Title: Contaminación ambiental y cambio climático Destination: 1 Item: Title: Antiinflamatorios no esteroideos (AINE) Destination: 1 Children: Item: Title: Alérgenos Destination: 1 Item: Title: Vacunación antigripal Destination: 1 Item: Title: Vacunación antineumocócica Destination: 1 Item: Title: Vacunación frente a SARS-CoV-2 Destination: 1 Item: Title: Organización unidades asistenciales en asma Destination: 1 Children: Item: Title: Características generales. Dotación Destination: 1 Item: Title: Recursos técnicos Destination: 1 Item: Title: Recursos humanos Destination: 1 Item: Title: Formación acreditada en asma Destination: 1 Item: Title: Actividad docente Destination: 1 Item: Title: Actividad investigadora Destination: 1 Item: Title: Unidades multidisciplinares Destination: 1 Item: Title: Criterios de derivación Destination: 1 Item: Title: Indicadores de resultados en salud Destination: 1 Item: Title: Financiación Destination: 1 Item: Title: Conflicto de intereses Destination: 1 Item: Title: Contribución de los autores Destination: 1 Item: Title: Agradecimientos Destination: 1 Item: Title: Anexo Material adicional Destination: 1 Item: Title: Anexo Participantes del Grupo Validador de Recomendaciones, nombrados por las sociedades autonómicas y el área de asma de ... 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Actualización 2022 Francisco Javier Alvarez-Gutiérrez Marina Blanco-Aparicio Francisco Casas-Maldonado Vicente Plaza Francisco Javier González-Barcala José Ángel Carretero-Gracia Manuel Castilla-Martínez Carolina Cisneros David Diaz-Pérez Christian Domingo-Ribas Eva Martínez-Moragon Xavier Muñoz Alicia Padilla-Galo Miguel Perpiñá-Tordera Gregorio Soto-Campos Open Respiratory Archives, Corrected proof. doi:10.1016/j.opresp.2022.100192 Sociedad Española de Neumología y Cirugía Torácica (SEPAR) Asma grave Diagnóstico Seguimiento Tratamiento Anticuerpos monoclonales journal Open Respiratory Archives © 2022 Publicado por Elsevier España, S.L.U. Todos los derechos reservados. 2659-6636 4 3 July-September 2022 10.1016/j.opresp.2022.100192 https://doi.org/10.1016/j.opresp.2022.100192 100192 100192 2010-04-23 true 10.1016/j.opresp.2022.100192 elsevier.com sciencedirect.com VoR 10.1016/j.opresp.2022.100192 noindex 2010-04-23 true sciencedirect.com elsevier.com sciencedirect.com elsevier.com Elsevier 2022-08-10T12:13:24Z 2022-12-22T15:22:26+05:30 2022-12-22T15:22:26+05:30 True Unknown Acrobat Distiller 11.0 (Windows) Asma grave; Diagnóstico; Seguimiento; Tratamiento; Anticuerpos monoclonales uuid:ab463aa5-0b55-443f-87c5-1dbd1f1d3e19 uuid:4a182b6e-f401-4b37-88a0-c78d8b986e5a http://creativecommons.org/licenses/by-nc-nd/4.0/ Pages: Page: Label: 1 Annotations: Annotation: Subtype: Link Rect: 272, 798, 406, 803 Flags: Print Annotation: Subtype: Link Rect: 305, 715, 400, 720 Flags: Print Annotation: Subtype: Link Rect: 543, 645, 572, 674 Flags: Print Annotation: Subtype: Link Rect: 251, 644, 270, 651 Flags: Print Destination: 1629 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