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first-line cisplatin-ineligible patients Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@757942a1 Item: Title: 2.1.2 First-line maintenance approach Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@4a87761d Children: Item: Title: 2.1.2.1 The rationale for maintenance therapy Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@66d1af89 Item: Title: 2.1.2.2 First-line maintenance strategy with checkpoint inhibitors Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@8646db9 Item: Title: 2.1.3 Other strategies in first-line Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@37374a5e Children: Item: Title: 2.1.3.1 Checkpoint inhibitor plus chemotherapy as first-line combination approach Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@4671e53b Item: Title: 2.1.3.2 Two checkpoint inhibitors as first-line combination approach Destination: 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Joaquim Bellmunt Subject: Critical Reviews in Oncology / Hematology, 174 (2022) 103683. doi:10.1016/j.critrevonc.2022.103683 Keywords: Urothelial carcinoma (UC),Bladder cancer,Platinum-based chemotherapy,Checkpoint inhibitors (CPIs),Avelumab,Switch maintenance,Antibody drug-conjugate (ADC) Creator: Elsevier Producer: Acrobat Distiller 8.1.0 (Windows) CreationDate: Sat May 21 15:36:35 CEST 2022 ModDate: Sat May 21 18:48:24 CEST 2022 ID: 0xdde347111f2c1815f961eca96677dda2, 0x5028170d30aaee9cd60237889cda7775 Filters: FilterPipeline: FlateDecode FilterPipeline: DCTDecode Images: Image: NisoImageMetadata: FormatName: image/jpg CompressionScheme: JPEG ImageWidth: 236 ImageHeight: 298 BitsPerSample: 8 BitsPerSampleUnit: integer Image: NisoImageMetadata: FormatName: image/jpg CompressionScheme: JPEG ImageWidth: 248 ImageHeight: 271 BitsPerSample: 8 BitsPerSampleUnit: integer Fonts: Type0: Font: BaseFont: FPKAXI+CharisSIL-Bold Encoding: Identity-H ToUnicode: true Font: BaseFont: 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Critical Reviews in Oncology / Hematology, 174 (2022) 103683. doi:10.1016/j.critrevonc.2022.103683 Urothelial carcinoma (UC) Bladder cancer Platinum-based chemotherapy Checkpoint inhibitors (CPIs) Avelumab Switch maintenance Antibody drug-conjugate (ADC) Recent therapeutic advances in urothelial carcinoma: A paradigm shift in disease management Joaquim Bellmunt Begoña P. Valderrama Javier Puente Enrique Grande M. Victoria Bolós Nuria Lainez Sergio Vázquez Pablo Maroto Miguel Ángel Climent Xavier Garcia del Muro José Ángel Arranz Ignacio Durán journal Critical Reviews in Oncology / Hematology © 2022 The Authors. 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