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Keywords: cARB-eS-19 study, carbapenemases, whole genome sequencing, klebsiella pneumoniae, High-risk clones Author: Jesús OTEO-IGLESIAS Creator: LaTeX with hyperref package Producer: pdfTeX-1.40.18 CreationDate: Fri Jun 24 11:51:08 2022 CEST ModDate: Fri Jun 24 15:21:15 2022 CEST Tagged: no UserProperties: no Suspects: no Form: none JavaScript: no Pages: 13 Encrypted: no Page size: 595.276 x 779.528 pts Page rot: 0 File size: 3906495 bytes Optimized: no PDF version: 1.5 name type encoding emb sub uni object ID ------------------------------------ ----------------- ---------------- --- --- --- --------- SFNYNC+MinionPro-Regular Type 1 Custom yes yes no 24 0 BZJCBA+HelveticaNeueLTStd-Bd Type 1 Custom yes yes no 25 0 GGWKHX+HelveticaNeueLTStd-Lt Type 1 Custom yes yes no 26 0 TXZIYG+HelveticaNeueLTStd-BdIt Type 1 Custom yes yes no 31 0 MOGPXN+HelveticaNeueLTStd-LtIt Type 1 Custom yes yes no 32 0 ETDODR+HelveticaNeueLTStd-MdIt Type 1 Custom yes yes no 33 0 NOUQCI+RBLMI Type 1 Builtin yes yes no 34 0 AHMKPO+MTSYN Type 1 Builtin yes yes no 87 0 IBGENG+MinionPro-It Type 1 Custom yes yes no 92 0 ZIHTQO+MinionPro-Bold Type 1 Custom yes yes no 156 0 CMERJW+MTGU Type 1 Builtin yes yes no 170 0 SIUEQJ+MTSYB Type 1 Builtin yes yes no 297 0 Jhove (Rel. 1.22.1, 2019-04-17) Date: 2023-07-14 02:38:44 CEST RepresentationInformation: 277656.pdf ReportingModule: PDF-hul, Rel. 1.12.1 (2019-04-17) LastModified: 2023-07-13 09:51:37 CEST Size: 3906495 Format: PDF Version: 1.5 Status: Well-Formed and valid SignatureMatches: PDF-hul MIMEtype: application/pdf PDFMetadata: Objects: 695 FreeObjects: 3 IncrementalUpdates: 1 DocumentCatalog: PageLayout: SinglePage PageMode: UseOutlines Outlines: Item: Title: CARB-ES-19 Multicenter Study of Carbapenemase-Producing Klebsiella pneumoniae and Escherichia coli From All Spanish Provinces Reveals Interregional Spread of High-Risk Clones Such as ST307/OXA-48 and ST512/KPC-3 Children: Item: Title: Introduction Item: Title: Materials and Methods Children: Item: Title: Study Design and Isolates Item: Title: Drug Susceptibility Testing Item: Title: Genomic Library Preparation and Sequence Analysis Item: Title: Phylogenetic Analysis Item: Title: Analysis of Antimicrobial Resistance, Virulence Genes, and Capsular Locus Item: Title: Characterization of Plasmids Carrying Carbapenemase Genes Item: Title: Ethics Statement Item: Title: Results Children: Item: Title: Bacterial Isolates, Prevalence, Incidence, and Carbapenemase Types Item: Title: Antibiotic Susceptibility Testing Item: Title: High-Risk Clones of Carbapenemase-Producing Klebsiella pneumoniae Item: Title: Phylogenetic Analysis of Carbapenemase-Producing Klebsiella pneumoniae Item: Title: Identification and Distribution of Resistance and Virulence Genes Item: Title: Characterization of Plasmids Harboring Carbapenemases Genes Item: Title: Discussion Item: Title: Data Availability Statement Item: Title: Ethics Statement Item: Title: GEMARA/GEIRAS-SEIMC/REIPI CARB-ES-19 Study Group Item: Title: Author Contributions Item: Title: Funding Item: Title: Acknowledgments Item: Title: Supplementary Material Item: Title: References Info: Title: CARB-ES-19 Multicenter Study of Carbapenemase-Producing Klebsiella pneumoniae and Escherichia coli From All Spanish Provinces Reveals Interregional Spread of High-Risk Clones Such as ST307/OXA-48 and ST512/KPC-3 Author: Jesús OTEO-IGLESIAS Subject: Objectives: CARB-ES-19 is a comprehensive, multicenter, nationwide study integrating whole-genome sequencing (WGS) in the surveillance of carbapenemase-producing K. pneumoniae (CP-Kpn) and E. coli (CP-Eco) to determine their incidence, geographical distribution, phylogeny, and resistance mechanisms in Spain. 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Annotation: Subtype: Link Rect: 302, 545, 329, 555 Annotation: Subtype: Link Rect: 43, 29, 119, 38 Annotation: Subtype: Link Rect: 122, 29, 182, 38 Annotation: Subtype: Link Rect: 430, 29, 551, 38 Checksum: cfd673ef Type: CRC32 Checksum: 14ca1b42b803a909e36e73dd1d009609 Type: MD5 Checksum: 72d18b61509d451c986d7959910723ec3572a434 Type: SHA-1