8bbdfaeb6bd2105cc9fb811a5e898bd9 277707.pdf 3b5bf9901d05be6cdd5aa759105226be2051329a 277707.pdf cf6a2474f5f9cdd1a2511ee2fe3eb944e0708c0919c2a1775d893ae3f921a33b 277707.pdf Title: Neurofilaments contribution in clinic: state of the art Subject: Neurological biomarkers are particularly valuable to clinicians as they can be used for diagnosis, prognosis, or response to treatment. Keywords: neurofilament, biomarkers, neurological and neurodegenerative diseases, cut-off, biological fluids Author: Sylvain Lehmann Creator: LaTeX with hyperref package Producer: pdfTeX-1.40.12 CreationDate: Sat Oct 29 05:59:39 2022 CEST ModDate: Sat Oct 29 06:23:55 2022 CEST Tagged: no UserProperties: no Suspects: no Form: none JavaScript: no Pages: 19 Encrypted: no Page size: 595.44 x 841.68 pts Page rot: 0 File size: 1598254 bytes Optimized: yes PDF version: 1.6 name type encoding emb sub uni object ID ------------------------------------ ----------------- ---------------- --- --- --- --------- GAFJEF+MTSYN Type 1 Builtin yes yes no 1336 0 LPYGKN+MuseoSans-700 Type 1 Custom yes yes no 1317 0 KYETIB+MuseoSans-300 Type 1 Custom yes yes no 1318 0 EQENKS+MuseoSans-500 Type 1 Custom yes yes no 1327 0 FHIQZS+MinionPro-Bold Type 1 Custom yes yes no 934 0 ZQXQKI+MSAM7 Type 1 Builtin yes yes no 933 0 EXKUYR+MinionPro-Regular Type 1 Custom yes yes no 931 0 ITOYRU+MTGU Type 1 Builtin yes yes no 940 0 QHBEVL+MinionPro-It Type 1 Custom yes yes no 943 0 GEORVV+RBLMI Type 1 Builtin yes yes no 950 0 Jhove (Rel. 1.22.1, 2019-04-17) Date: 2023-07-21 02:36:58 CEST RepresentationInformation: 277707.pdf ReportingModule: PDF-hul, Rel. 1.12.1 (2019-04-17) LastModified: 2023-07-20 13:40:41 CEST Size: 1598254 Format: PDF Version: 1.6 Status: Well-Formed and valid SignatureMatches: PDF-hul MIMEtype: application/pdf Profile: Linearized PDF PDFMetadata: Objects: 1504 FreeObjects: 1 IncrementalUpdates: 1 DocumentCatalog: ViewerPreferences: HideToolbar: false HideMenubar: false HideWindowUI: false FitWindow: true CenterWindow: false DisplayDocTitle: false NonFullScreenPageMode: UseNone Direction: L2R ViewArea: CropBox ViewClip: CropBox PrintArea: CropBox PageClip: CropBox PageLayout: SinglePage PageMode: UseOutlines Outlines: Item: Title: Neurofilaments contribution in clinic: state of the art Children: Item: Title: Introduction Item: Title: NfL and neurodegenerative diseases Children: Item: Title: Alzheimer's disease Children: Item: Title: Background and state of the art Item: Title: Diagnostic and prognostic values Item: Title: Position of NfL compared to other biomarkers and cut-off value Item: Title: Parkinson's syndromes and synucleopathies Children: Item: Title: Background and state of the art Item: Title: Diagnostic and prognostic values Item: Title: Position of NfL compared to other biomarkers and cut-off value Item: Title: Fronto-temporal dementia (FTD) Children: Item: Title: Background and state of the art Item: Title: Diagnostic and prognostic values Item: Title: Position of NfL compared to other biomarkers and cut-off value Item: Title: Other neurodegenerative proteinopathies Item: Title: Amyotrophic lateral sclerosis Children: Item: Title: Background and state of the art Item: Title: Diagnostic and prognostic values Item: Title: Position of NfL compared to other biomarkers and cut-off value Item: Title: Multiple sclerosis Children: Item: Title: Background and state of the art Item: Title: Diagnostic and prognostic values Item: Title: Blood NfL as a marker of treatment response Item: Title: Position of NfL compared to other biomarkers and cut-off value Item: Title: NfL and neurological damages Children: Item: Title: Traumatic brain injuries Children: Item: Title: Background and state of the art Item: Title: Diagnostic and prognostic values Item: Title: Position of NfL compared to other biomarkers and cut-off value Item: Title: Stroke Item: Title: Background and state of the art Children: Item: Title: Diagnostic and prognostic values Item: Title: Position of NfL compared to other biomarkers and cut-off value Item: Title: Neurological damages in oncology Children: Item: Title: Background and state of the art Item: Title: Diagnostic and prognostic values Item: Title: Response to cancer therapy Item: Title: Position of NfL compared to other biomarkers and cut-off value Item: Title: Other NfL applications Item: Title: Conclusion Item: Title: Author contributions Item: Title: Funding Item: Title: Conflict of interest Item: Title: Publisher's note Item: Title: References Info: Title: Neurofilaments contribution in clinic: state of the art Author: Sylvain Lehmann Subject: Neurological biomarkers are particularly valuable to clinicians as they can be used for diagnosis, prognosis, or response to treatment. 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