918079b72897d6c63675e52de38ff085 280853.pdf 48af8cc724aaec2cc384fc634f80ddb0b9a5340a 280853.pdf 53986e9adcf9d27ecc3f02a6e1813166820b39d842b4b5f2307ab98113c1bf07 280853.pdf Title: Subject: 10.2217/fon-2021-1286 Keywords: Author: Creator: LaTeX with hyperref package Producer: Acrobat Distiller 9.0.0 (Windows) CreationDate: Wed Feb 2 10:28:25 2022 CET ModDate: Wed Feb 2 10:28:25 2022 CET Tagged: no UserProperties: no Suspects: no Form: none JavaScript: no Pages: 11 Encrypted: no Page size: 589.92 x 793.6 pts Page rot: 0 File size: 3603164 bytes Optimized: no PDF version: 1.6 name type encoding emb sub uni object ID ------------------------------------ ----------------- ---------------- --- --- --- --------- IOCEKP+FrutigerLTStd-Roman Type 1C Custom yes yes yes 22 0 IOCGKE+FrutigerLTStd-LightItalic Type 1C Custom yes yes yes 23 0 IOCGKF+RMTMI Type 1C Custom yes yes yes 24 0 IOCGLG+FrutigerLTStd-Light Type 1C Custom yes yes yes 25 0 IOCGLH+RMTMUB Type 1C Custom yes yes yes 26 0 IOCGLI+FrutigerLTStd-Bold Type 1C Custom yes yes yes 27 0 IOCGOH+MyriadPro-SemiboldIt Type 1C Custom yes yes yes 28 0 IOCGOI+MyriadPro-Light Type 1C Custom yes yes yes 29 0 IOCGOJ+MTSY Type 1C Custom yes yes yes 30 0 IOCGOK+FrutigerLTStd-Italic Type 1C Custom yes yes yes 43 0 IOCGPL+AGaramond-Regular Type 1C Custom yes yes no 44 0 IOCGPM+AGaramond-Italic Type 1C WinAnsi yes yes no 45 0 IOCHGE+MTGU Type 1C Custom yes yes yes 59 0 IOCKIC+HelveticaLTStd-Bold Type 1C WinAnsi yes yes no 75 0 IOCKID+HelveticaLTStd-Roman Type 1C WinAnsi yes yes no 76 0 IOCLJN+HelveticaLTStd-Bold Type 1C WinAnsi yes yes no 106 0 IOCLJO+HelveticaLTStd-Roman Type 1C Custom yes yes yes 107 0 IOCMDL+SFRM0600 Type 1C Custom yes yes yes 108 0 IOCMDM+CMBSY10 Type 1C Custom yes yes yes 109 0 IOCNAI+SFRM0800 Type 1C Custom yes yes yes 182 0 IOCOPN+AGaramond-Bold Type 1C MacRoman yes yes no 279 0 Jhove (Rel. 1.22.1, 2019-04-17) Date: 2023-07-25 02:30:47 CEST RepresentationInformation: 280853.pdf ReportingModule: PDF-hul, Rel. 1.12.1 (2019-04-17) LastModified: 2023-07-24 16:29:27 CEST Size: 3603164 Format: PDF Version: 1.6 Status: Well-Formed and valid SignatureMatches: PDF-hul MIMEtype: application/pdf PDFMetadata: Objects: 0 FreeObjects: 1 IncrementalUpdates: 0 DocumentCatalog: PageLayout: SinglePage PageMode: UseNone Filters: FilterPipeline: FlateDecode Images: Image: NisoImageMetadata: FormatName: image/png ImageWidth: 1023 ImageHeight: 864 ColorSpace: CMYK BitsPerSample: 8 BitsPerSampleUnit: integer Filter: FlateDecode Image: NisoImageMetadata: FormatName: image/png ImageWidth: 55 ImageHeight: 55 BitsPerSample: 8 BitsPerSampleUnit: integer Filter: FlateDecode Image: NisoImageMetadata: FormatName: image/png ImageWidth: 521 ImageHeight: 510 ColorSpace: CMYK BitsPerSample: 8 BitsPerSampleUnit: integer Filter: FlateDecode Image: NisoImageMetadata: FormatName: image/png ImageWidth: 521 ImageHeight: 510 ColorSpace: CMYK BitsPerSample: 8 BitsPerSampleUnit: integer Filter: FlateDecode Image: NisoImageMetadata: FormatName: image/png ImageWidth: 521 ImageHeight: 510 ColorSpace: CMYK BitsPerSample: 8 BitsPerSampleUnit: integer Filter: FlateDecode Image: NisoImageMetadata: FormatName: image/png ImageWidth: 348 ImageHeight: 848 ColorSpace: CMYK BitsPerSample: 8 BitsPerSampleUnit: integer Filter: FlateDecode Image: NisoImageMetadata: FormatName: image/png ImageWidth: 520 ImageHeight: 510 ColorSpace: CMYK BitsPerSample: 8 BitsPerSampleUnit: integer Filter: FlateDecode Image: NisoImageMetadata: FormatName: image/png ImageWidth: 521 ImageHeight: 510 ColorSpace: CMYK BitsPerSample: 8 BitsPerSampleUnit: integer Filter: FlateDecode Image: NisoImageMetadata: FormatName: image/png ImageWidth: 521 ImageHeight: 510 ColorSpace: CMYK BitsPerSample: 8 BitsPerSampleUnit: integer Filter: FlateDecode Image: NisoImageMetadata: FormatName: image/png ImageWidth: 520 ImageHeight: 510 ColorSpace: CMYK BitsPerSample: 8 BitsPerSampleUnit: integer Filter: FlateDecode Image: NisoImageMetadata: FormatName: image/png ImageWidth: 348 ImageHeight: 171 BitsPerSample: 8 BitsPerSampleUnit: integer Filter: FlateDecode Image: NisoImageMetadata: FormatName: image/png ImageWidth: 521 ImageHeight: 510 ColorSpace: CMYK BitsPerSample: 8 BitsPerSampleUnit: integer Filter: FlateDecode Image: NisoImageMetadata: FormatName: image/png ImageWidth: 5 ImageHeight: 543 BitsPerSample: 8 BitsPerSampleUnit: integer Filter: FlateDecode Image: NisoImageMetadata: FormatName: image/png ImageWidth: 94 ImageHeight: 332 BitsPerSample: 8 BitsPerSampleUnit: integer Filter: FlateDecode Image: NisoImageMetadata: FormatName: image/png ImageWidth: 564 ImageHeight: 538 BitsPerSample: 8 BitsPerSampleUnit: integer Filter: FlateDecode Image: NisoImageMetadata: FormatName: image/png ImageWidth: 6 ImageHeight: 4 ColorSpace: CMYK BitsPerSample: 8 BitsPerSampleUnit: integer Filter: FlateDecode Image: NisoImageMetadata: FormatName: image/png ImageWidth: 4 ImageHeight: 465 BitsPerSample: 8 BitsPerSampleUnit: integer Filter: FlateDecode Image: NisoImageMetadata: FormatName: image/png ImageWidth: 23 ImageHeight: 4 ColorSpace: CMYK BitsPerSample: 8 BitsPerSampleUnit: integer Filter: FlateDecode Image: NisoImageMetadata: FormatName: image/png ImageWidth: 5 ImageHeight: 543 BitsPerSample: 8 BitsPerSampleUnit: integer Filter: FlateDecode Image: NisoImageMetadata: FormatName: image/png ImageWidth: 564 ImageHeight: 245 BitsPerSample: 8 BitsPerSampleUnit: integer Filter: FlateDecode Image: NisoImageMetadata: FormatName: image/png ImageWidth: 116 ImageHeight: 544 BitsPerSample: 8 BitsPerSampleUnit: integer Filter: FlateDecode Image: NisoImageMetadata: FormatName: image/png ImageWidth: 7 ImageHeight: 4 ColorSpace: CMYK BitsPerSample: 8 BitsPerSampleUnit: integer Filter: FlateDecode Image: NisoImageMetadata: FormatName: image/png ImageWidth: 94 ImageHeight: 335 BitsPerSample: 8 BitsPerSampleUnit: integer Filter: FlateDecode Image: NisoImageMetadata: FormatName: image/png ImageWidth: 330 ImageHeight: 133 BitsPerSample: 8 BitsPerSampleUnit: integer Filter: FlateDecode Image: NisoImageMetadata: FormatName: image/png ImageWidth: 564 ImageHeight: 465 BitsPerSample: 8 BitsPerSampleUnit: integer Filter: FlateDecode Image: NisoImageMetadata: FormatName: image/png ImageWidth: 398 ImageHeight: 215 BitsPerSample: 8 BitsPerSampleUnit: integer Filter: FlateDecode Image: NisoImageMetadata: FormatName: image/png ImageWidth: 192 ImageHeight: 187 BitsPerSample: 8 BitsPerSampleUnit: integer Filter: FlateDecode Image: NisoImageMetadata: FormatName: image/png ImageWidth: 29 ImageHeight: 4 ColorSpace: CMYK BitsPerSample: 8 BitsPerSampleUnit: integer Filter: FlateDecode Image: NisoImageMetadata: FormatName: image/png ImageWidth: 94 ImageHeight: 335 BitsPerSample: 8 BitsPerSampleUnit: integer Filter: FlateDecode Fonts: Type1: Font: BaseFont: IOCLJN+HelveticaLTStd-Bold FontSubset: true FirstChar: 32 LastChar: 135 FontDescriptor: FontName: IOCLJN+HelveticaLTStd-Bold Flags: Nonsymbolic, ForceBold FontBBox: -170, -228, 1003, 962 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: IOCGOK+FrutigerLTStd-Italic FontSubset: true FirstChar: 46 LastChar: 116 FontDescriptor: FontName: IOCGOK+FrutigerLTStd-Italic Flags: Symbolic, Italic FontBBox: -169, -250, 1091, 930 FontFile3: true EncodingDictionary: Differences: true ToUnicode: true Font: BaseFont: IOCKIC+HelveticaLTStd-Bold FontSubset: true FirstChar: 47 LastChar: 116 FontDescriptor: FontName: IOCKIC+HelveticaLTStd-Bold Flags: Nonsymbolic FontBBox: -157, -250, 1126, 952 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: IOCLJO+HelveticaLTStd-Roman FontSubset: true FirstChar: 2 LastChar: 182 FontDescriptor: FontName: IOCLJO+HelveticaLTStd-Roman Flags: Symbolic FontBBox: -166, -225, 1000, 931 FontFile3: true EncodingDictionary: Differences: true ToUnicode: true Font: BaseFont: IOCGPL+AGaramond-Regular FontSubset: true FirstChar: 30 LastChar: 180 FontDescriptor: FontName: IOCGPL+AGaramond-Regular Flags: Serif, Nonsymbolic FontBBox: -183, -269, 1099, 851 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true Font: BaseFont: IOCKID+HelveticaLTStd-Roman FontSubset: true FirstChar: 32 LastChar: 121 FontDescriptor: FontName: IOCKID+HelveticaLTStd-Roman Flags: Nonsymbolic FontBBox: -157, -250, 1126, 952 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: IOCMDL+SFRM0600 FontSubset: true FirstChar: 129 LastChar: 182 FontDescriptor: FontName: IOCMDL+SFRM0600 Flags: Serif, Symbolic FontBBox: -210, -320, 1719, 944 FontFile3: true EncodingDictionary: Differences: true ToUnicode: true Font: BaseFont: IOCGPM+AGaramond-Italic FontSubset: true FirstChar: 46 LastChar: 121 FontDescriptor: FontName: IOCGPM+AGaramond-Italic Flags: Serif, Nonsymbolic, Italic FontBBox: -182, -285, 1150, 851 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: IOCMDM+CMBSY10 FontSubset: true FirstChar: 167 LastChar: 167 FontDescriptor: FontName: IOCMDM+CMBSY10 Flags: Symbolic, Italic, ForceBold FontBBox: -26, -940, 1332, 825 FontFile3: true EncodingDictionary: Differences: true ToUnicode: true Font: BaseFont: IOCEKP+FrutigerLTStd-Roman FontSubset: true FirstChar: 2 LastChar: 144 FontDescriptor: FontName: IOCEKP+FrutigerLTStd-Roman Flags: Symbolic FontBBox: -169, -250, 1000, 935 FontFile3: true EncodingDictionary: Differences: true ToUnicode: true Font: BaseFont: IOCNAI+SFRM0800 FontSubset: true FirstChar: 128 LastChar: 129 FontDescriptor: FontName: IOCNAI+SFRM0800 Flags: Serif, Symbolic FontBBox: -203, -320, 1554, 938 FontFile3: true EncodingDictionary: Differences: true ToUnicode: true Font: BaseFont: IOCGKE+FrutigerLTStd-LightItalic FontSubset: true FirstChar: 44 LastChar: 117 FontDescriptor: FontName: IOCGKE+FrutigerLTStd-LightItalic Flags: Symbolic, Italic FontBBox: -143, -250, 1031, 917 FontFile3: true EncodingDictionary: Differences: true ToUnicode: true Font: BaseFont: IOCOPN+AGaramond-Bold FontSubset: true FirstChar: 44 LastChar: 222 FontDescriptor: FontName: IOCOPN+AGaramond-Bold Flags: Serif, Nonsymbolic, ForceBold FontBBox: -158, -269, 1147, 862 FontFile3: true Encoding: MacRomanEncoding Font: BaseFont: IOCGKF+RMTMI FontSubset: true FirstChar: 47 LastChar: 62 FontDescriptor: FontName: IOCGKF+RMTMI Flags: Symbolic, Italic FontBBox: 0, -213, 987, 680 FontFile3: true EncodingDictionary: Differences: true ToUnicode: true Font: BaseFont: IOCGLG+FrutigerLTStd-Light FontSubset: true FirstChar: 2 LastChar: 180 FontDescriptor: FontName: IOCGLG+FrutigerLTStd-Light Flags: Symbolic FontBBox: -152, -250, 1000, 911 FontFile3: true EncodingDictionary: Differences: true ToUnicode: true Font: BaseFont: IOCGLH+RMTMUB FontSubset: true FirstChar: 47 LastChar: 47 FontDescriptor: FontName: IOCGLH+RMTMUB Flags: Symbolic, ForceBold FontBBox: 0, -208, 994, 699 FontFile3: true EncodingDictionary: Differences: true ToUnicode: true Font: BaseFont: IOCGLI+FrutigerLTStd-Bold FontSubset: true FirstChar: 38 LastChar: 121 FontDescriptor: FontName: IOCGLI+FrutigerLTStd-Bold Flags: Symbolic, ForceBold FontBBox: -166, -250, 1000, 935 FontFile3: true EncodingDictionary: Differences: true ToUnicode: true Font: BaseFont: IOCHGE+MTGU FontSubset: true FirstChar: 2 LastChar: 4 FontDescriptor: FontName: IOCHGE+MTGU Flags: Symbolic FontBBox: 24, -213, 839, 683 FontFile3: true EncodingDictionary: Differences: true ToUnicode: true Font: BaseFont: IOCGOH+MyriadPro-SemiboldIt FontSubset: true FirstChar: 46 LastChar: 117 FontDescriptor: FontName: IOCGOH+MyriadPro-SemiboldIt Flags: Symbolic, Italic, ForceBold FontBBox: -103, -250, 1165, 882 FontFile3: true EncodingDictionary: Differences: true ToUnicode: true Font: BaseFont: IOCGOI+MyriadPro-Light FontSubset: true FirstChar: 40 LastChar: 117 FontDescriptor: FontName: IOCGOI+MyriadPro-Light Flags: Symbolic FontBBox: -49, -250, 1046, 883 FontFile3: true EncodingDictionary: Differences: true ToUnicode: true Font: BaseFont: IOCGOJ+MTSY FontSubset: true FirstChar: 2 LastChar: 177 FontDescriptor: FontName: IOCGOJ+MTSY Flags: Symbolic FontBBox: 0, -954, 1043, 796 FontFile3: true EncodingDictionary: Differences: true ToUnicode: true XMP: Issue 10.2217/fon-2021-1286 VoR adjuvant, bempegaldesleukin, cutaneous melanoma, IL-2 pathway, immune checkpoint inhibitor combinations, immunotherapy, nivolumab, NKTR-214, PD-1, PD-L1 Acrobat Distiller 9.0.0 (Windows) 2022-02-02T04:28:25-05:00 2022-02-02T04:28:25-05:00 LaTeX with hyperref package 2022-02-02T04:28:29-05:00 PIVOT-12: a Phase III study of adjuvant bempegaldesleukin plus nivolumab in resected stage III/IV melanoma at high risk for recurrence 10.2217/fon-2021-1286 © 2022 The Authors True https://www.future-science.com/terms Pages: Page: Label: 1 Annotations: Annotation: Subtype: Link Rect: 172, 561, 184, 572 Annotation: Subtype: Link Rect: 168, 104, 227, 115 Page: Label: 2 Page: Label: 3 Page: Label: 4 Page: Label: 5 Page: Label: 6 Page: Label: 7 Page: Label: 8 Annotations: Annotation: Subtype: Link Rect: 99, 517, 540, 542 Page: Label: 9 Annotations: Annotation: Subtype: Link Rect: 64, 173, 238, 183 Page: Label: 10 Annotations: Annotation: Subtype: Link Rect: 117, 644, 342, 654 Annotation: Subtype: Link Rect: 117, 595, 365, 606 Annotation: Subtype: Link Rect: 268, 581, 422, 592 Annotation: Subtype: Link Rect: 269, 567, 422, 578 Page: Label: 11 Checksum: 354b9c8f Type: CRC32 Checksum: 918079b72897d6c63675e52de38ff085 Type: MD5 Checksum: 48af8cc724aaec2cc384fc634f80ddb0b9a5340a Type: SHA-1