2f0c4a1164998707c6eac803a6cb7b5d 280885.pdf ce560310f90b12c1ad53daad15d7c2df5826d06b 280885.pdf 6fc03f4cc690bef1f4e48b545f09644bf2ef3ab7570a59a3fc6554bfa04dea10 280885.pdf Title: Metabolic-associated fatty liver disease: From simple steatosis toward liver cirrhosis and potential complications. Proceedings of the Third Translational Hepatology Meeting, organized by the Spanish Association for the Study of the Liver (AEEH) Subject: Gastroenterología y Hepatología, 45 (2022) 724-734. doi:10.1016/j.gastrohep.2022.02.005 Keywords: Author: Rocío Gallego-Durán Creator: Elsevier Producer: Acrobat Distiller 11.0 (Windows) CreationDate: Fri Oct 28 18:30:33 2022 CEST ModDate: Fri Oct 28 13:09:19 2022 CEST Tagged: yes UserProperties: no Suspects: no Form: none JavaScript: no Pages: 11 Encrypted: no Page size: 595.28 x 793.7 pts Page rot: 0 File size: 489153 bytes Optimized: yes PDF version: 1.7 name type encoding emb sub uni object ID ------------------------------------ ----------------- ---------------- --- --- --- --------- ADNEKP+TrebuchetMS Type 1C Custom yes yes yes 701 0 ADNEMA+Times-Roman Type 1C WinAnsi yes yes no 702 0 ADNEPP+Univers Type 1C Custom yes yes yes 703 0 ADNFFO+TrebuchetMS-Bold Type 1C Custom yes yes yes 713 0 ADNFFP+Trebuchet-BoldItalic Type 1C Custom yes yes yes 714 0 ADNFGP+NmtmibA Type 1C Custom yes yes yes 715 0 ADNFIA+MTSYB Type 1C Custom yes yes yes 726 0 ADNFJB+TrebuchetMS-Italic Type 1C Custom yes yes yes 722 0 ADNFKB+MTSY Type 1C Custom yes yes yes 731 0 ADNFPA+Nmtmi Type 1C Custom yes yes yes 337 0 ADNHAK+MathematicalPi-One Type 1C Custom yes yes no 338 0 Jhove (Rel. 1.22.1, 2019-04-17) Date: 2023-07-28 02:41:13 CEST RepresentationInformation: 280885.pdf ReportingModule: PDF-hul, Rel. 1.12.1 (2019-04-17) LastModified: 2023-07-27 17:24:48 CEST Size: 489153 Format: PDF Version: 1.7 Status: Well-Formed and valid SignatureMatches: PDF-hul MIMEtype: application/pdf Profile: Linearized PDF PDFMetadata: Objects: 795 FreeObjects: 82 IncrementalUpdates: 1 DocumentCatalog: PageLayout: SinglePage PageMode: UseOutlines Language: EN Outlines: Item: Title: Metabolic-associated fatty liver disease: From simple steatosis toward liver cirrhosis and potential complications. Procee... Destination: 1 Children: Item: Title: Definition, comorbidities and pathophysiology Destination: 1 Children: Item: Title: Introduction Destination: 1 Item: Title: MAFLD pathophysiology Destination: 1 Item: Title: Main unresolved clinical issues in MAFLD Destination: 1 Item: Title: Role of sinusoidal cells in MAFLD Destination: 1 Item: Title: Role of fat in MAFLD Destination: 1 Item: Title: Immune and systemic inflammatory disorders in MAFLD Destination: 1 Item: Title: Metabolic alterations of bile acids during MAFLD progression Destination: 1 Item: Title: Advanced MASH – pathophysiology of decompensated cirrhosis Destination: 1 Item: Title: Carcinogenesis in MAFLD Destination: 1 Item: Title: Update on the mechanisms of liver injury in MAFLD Destination: 1 Children: Item: Title: Adipose tissue and liver crosstalk Destination: 1 Item: Title: Mitochondrial (dys)function in MAFLD Destination: 1 Item: Title: Oxidative stress and cell death Destination: 1 Item: Title: Inflammation and fibrogenesis Destination: 1 Item: Title: How to approach MAFLD Destination: 1 Children: Item: Title: Genetics, epigenetics and other risk factors Destination: 1 Item: Title: Nutritional geometry in MAFLD Destination: 1 Item: Title: Role of the microbiome in immunological and inflammatory alterations in MAFLD Destination: 1 Item: Title: Methods and technologies for the study of MAFLD Destination: 1 Children: Item: Title: Omics and exosomes Destination: 1 Item: Title: Technological advances in the study of MAFLD Destination: 1 Item: Title: Animal models of MAFLD Destination: 1 Item: Title: The future in animal models Destination: 1 Item: Title: Conclusions Destination: 1 Item: Title: Conflict of interest Destination: 1 Item: Title: References Destination: 1 Info: Title: Metabolic-associated fatty liver disease: From simple steatosis toward liver cirrhosis and potential complications. Proceedings of the Third Translational Hepatology Meeting, organized by the Spanish Association for the Study of the Liver (AEEH) Author: Rocío Gallego-Durán Subject: Gastroenterología y Hepatología, 45 (2022) 724-734. doi:10.1016/j.gastrohep.2022.02.005 Keywords: Creator: Elsevier Producer: Acrobat Distiller 11.0 (Windows) CreationDate: Fri Oct 28 18:30:33 CEST 2022 ModDate: Fri Oct 28 13:39:19 CEST 2022 ID: 0x567041adba542a9517eb14f422c2be83, 0x583d062b2fbf7f43871e7c0c7a02c6fa Filters: FilterPipeline: FlateDecode FilterPipeline: DCTDecode Images: Image: NisoImageMetadata: FormatName: image/jpg CompressionScheme: JPEG ImageWidth: 308 ImageHeight: 337 ColorSpace: RGB BitsPerSample: 8 BitsPerSampleUnit: integer Image: NisoImageMetadata: FormatName: image/png ImageWidth: 121 ImageHeight: 120 BitsPerSample: 8 BitsPerSampleUnit: integer Filter: FlateDecode Image: NisoImageMetadata: FormatName: image/jpg CompressionScheme: JPEG ImageWidth: 295 ImageHeight: 372 ColorSpace: RGB BitsPerSample: 8 BitsPerSampleUnit: integer Fonts: Type1: Font: BaseFont: ADNFPA+Nmtmi FontSubset: true FirstChar: 97 LastChar: 97 FontDescriptor: FontName: ADNFPA+Nmtmi Flags: Symbolic FontBBox: -68, -213, 987, 737 FontFile3: true EncodingDictionary: Differences: true ToUnicode: true Font: BaseFont: ADNFJB+TrebuchetMS-Italic FontSubset: true FirstChar: 31 LastChar: 243 FontDescriptor: FontName: ADNFJB+TrebuchetMS-Italic Flags: Serif, Symbolic, Italic FontBBox: -86, -258, 1021, 946 FontFile3: true EncodingDictionary: Differences: true ToUnicode: true Font: BaseFont: ADNHAK+MathematicalPi-One FontSubset: true FirstChar: 2 LastChar: 4 FontDescriptor: FontName: ADNHAK+MathematicalPi-One Flags: Symbolic FontBBox: -30, -210, 1000, 779 FontFile3: true EncodingDictionary: Differences: true Font: BaseFont: ADNFIA+MTSYB FontSubset: true FirstChar: 2 LastChar: 2 FontDescriptor: FontName: ADNFIA+MTSYB Flags: Symbolic, ForceBold FontBBox: -16, -935, 1043, 896 FontFile3: true EncodingDictionary: Differences: true ToUnicode: true Font: BaseFont: ADNFFO+TrebuchetMS-Bold FontSubset: true FirstChar: 31 LastChar: 243 FontDescriptor: FontName: ADNFFO+TrebuchetMS-Bold Flags: Serif, Symbolic, ForceBold FontBBox: -101, -270, 1010, 980 FontFile3: true EncodingDictionary: Differences: true ToUnicode: true Font: BaseFont: ADNFFP+Trebuchet-BoldItalic FontSubset: true FirstChar: 72 LastChar: 121 FontDescriptor: FontName: ADNFFP+Trebuchet-BoldItalic Flags: Serif, Symbolic, Italic, ForceBold FontBBox: -74, -270, 1078, 940 FontFile3: true EncodingDictionary: Differences: true ToUnicode: true Font: BaseFont: ADNFGP+NmtmibA FontSubset: true FirstChar: 44 LastChar: 44 FontDescriptor: FontName: ADNFGP+NmtmibA Flags: Symbolic, ForceBold FontBBox: -71, -209, 987, 767 FontFile3: true EncodingDictionary: Differences: true ToUnicode: true Font: BaseFont: ADNFKB+MTSY FontSubset: true FirstChar: 2 LastChar: 138 FontDescriptor: FontName: ADNFKB+MTSY Flags: Symbolic FontBBox: 0, -954, 1043, 796 FontFile3: true EncodingDictionary: Differences: true ToUnicode: true Font: BaseFont: ADNEKP+TrebuchetMS FontSubset: true FirstChar: 31 LastChar: 252 FontDescriptor: FontName: ADNEKP+TrebuchetMS Flags: Serif, Symbolic FontBBox: -86, -262, 958, 939 FontFile3: true EncodingDictionary: Differences: true ToUnicode: true Font: BaseFont: ADNEMA+Times-Roman FontSubset: true FirstChar: 32 LastChar: 237 FontDescriptor: FontName: ADNEMA+Times-Roman Flags: Serif, Nonsymbolic FontBBox: -168, -218, 1000, 898 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: ADNEPP+Univers FontSubset: true FirstChar: 46 LastChar: 119 FontDescriptor: FontName: ADNEPP+Univers Flags: Symbolic FontBBox: -168, -250, 992, 947 FontFile3: true EncodingDictionary: Differences: true ToUnicode: true XMP: application/pdf 10.1016/j.gastrohep.2022.02.005 Metabolic-associated fatty liver disease: From simple steatosis toward liver cirrhosis and potential complications. Proceedings of the Third Translational Hepatology Meeting, organized by the Spanish Association for the Study of the Liver (AEEH) Rocío Gallego-Durán Agustín Albillos Javier Ampuero María Arechederra Rafael Bañares Ana Blas-García Genoveva Berná Esther Caparrós Teresa C. Delgado Juan Manuel Falcón-Pérez Rubén Francés Maite G. Fernández-Barrena Isabel Graupera Paula Iruzubieta Yulia A. Nevzorova Rubén Nogueiras Rocío I.R. Macías Franz Martín Guadalupe Sabio Germán Soriano Javier Vaquero Francisco Javier Cubero Jordi Gracia-Sancho MAFLD MASH Steatohepatitis Fibrosis Hepatocellular carcinoma Gastroenterología y Hepatología, 45 (2022) 724-734. doi:10.1016/j.gastrohep.2022.02.005 The Authors journal Gastroenterología y Hepatología © 2022 The Authors. Published by Elsevier España, S.L.U. 0210-5705 45 9 November 2022 724-734 724 734 10.1016/j.gastrohep.2022.02.005 https://doi.org/10.1016/j.gastrohep.2022.02.005 2010-04-23 true 10.1016/j.gastrohep.2022.02.005 elsevier.com sciencedirect.com VoR 10.1016/j.gastrohep.2022.02.005 noindex 2010-04-23 true sciencedirect.com elsevier.com Elsevier 2022-10-28T16:30:33Z 2022-10-28T16:39:19+05:30 True True Acrobat Distiller 11.0 (Windows) uuid:c136b614-743d-4de6-bd1c-b2419fec31f1 uuid:bd2876d3-1acd-4319-a2e2-dc167870a7d7 http://creativecommons.org/licenses/by-nc-nd/4.0/ Pages: Page: Label: 1 Annotations: Annotation: Subtype: Link Rect: 247, 803, 430, 810 Flags: Print Annotation: Subtype: Link Rect: 276, 711, 406, 717 Flags: Print Annotation: Subtype: Link Rect: 516, 627, 545, 656 Flags: Print Annotation: Subtype: Link Rect: 205, 539, 224, 545 Flags: Print Destination: 597 Annotation: Subtype: Link Rect: 213, 539, 231, 545 Flags: Print Destination: 597 Annotation: Subtype: Link Rect: 220, 539, 239, 545 Flags: Print Destination: 597 Annotation: Subtype: Link Rect: 320, 539, 339, 545 Flags: Print Destination: 597 Annotation: Subtype: Link Rect: 328, 539, 346, 545 Flags: Print Destination: 597 Annotation: Subtype: Link Rect: 431, 539, 450, 545 Flags: Print Destination: 597 Annotation: Subtype: Link Rect: 438, 539, 457, 545 Flags: Print Destination: 597 Annotation: Subtype: Link Rect: 446, 539, 465, 545 Flags: Print Destination: 597 Annotation: Subtype: Link Rect: 196, 525, 215, 531 Flags: Print Destination: 597 Annotation: Subtype: Link Rect: 203, 525, 222, 531 Flags: Print Destination: 597 Annotation: Subtype: Link Rect: 211, 525, 230, 531 Flags: Print Destination: 597 Annotation: Subtype: Link Rect: 306, 525, 325, 531 Flags: Print Destination: 597 Annotation: Subtype: Link Rect: 314, 525, 333, 531 Flags: Print Destination: 597 Annotation: Subtype: Link Rect: 321, 525, 340, 531 Flags: Print Destination: 597 Annotation: Subtype: Link Rect: 329, 525, 348, 531 Flags: Print Destination: 597 Annotation: Subtype: Link Rect: 428, 525, 446, 531 Flags: Print Destination: 597 Annotation: Subtype: Link Rect: 435, 525, 454, 531 Flags: Print Destination: 597 Annotation: Subtype: Link Rect: 441, 525, 460, 531 Flags: Print Destination: 1 Annotation: Subtype: Link Rect: 183, 511, 202, 518 Flags: Print Destination: 1 Annotation: Subtype: Link Rect: 189, 511, 207, 518 Flags: Print Destination: 1 Annotation: Subtype: Link Rect: 199, 511, 217, 518 Flags: Print Destination: 1 Annotation: Subtype: Link Rect: 302, 511, 320, 518 Flags: Print Destination: 597 Annotation: Subtype: Link Rect: 309, 511, 328, 518 Flags: Print Destination: 1 Annotation: Subtype: Link Rect: 317, 511, 335, 518 Flags: Print Destination: 1 Annotation: Subtype: Link Rect: 431, 511, 449, 518 Flags: Print Destination: 597 Annotation: Subtype: Link Rect: 438, 511, 457, 518 Flags: Print Destination: 1 Annotation: Subtype: Link Rect: 239, 497, 258, 504 Flags: Print Destination: 597 Annotation: Subtype: Link Rect: 246, 497, 265, 504 Flags: Print Destination: 1 Annotation: Subtype: Link Rect: 253, 497, 272, 504 Flags: Print Destination: 1 Annotation: Subtype: Link Rect: 348, 497, 367, 504 Flags: Print Destination: 597 Annotation: Subtype: Link Rect: 356, 497, 375, 504 Flags: Print Destination: 1 Annotation: Subtype: Link Rect: 363, 497, 382, 504 Flags: Print Destination: 1 Annotation: Subtype: Link Rect: 200, 483, 219, 490 Flags: Print Destination: 597 Annotation: Subtype: Link Rect: 207, 483, 226, 490 Flags: Print Destination: 597 Annotation: Subtype: Link Rect: 215, 483, 234, 490 Flags: Print Destination: 597 Annotation: Subtype: Link Rect: 315, 483, 333, 490 Flags: Print Destination: 597 Annotation: Subtype: Link Rect: 322, 483, 341, 490 Flags: Print Destination: 1 Annotation: Subtype: Link Rect: 426, 483, 445, 490 Flags: Print Destination: 597 Annotation: Subtype: Link Rect: 433, 483, 452, 490 Flags: Print Destination: 1 Annotation: Subtype: Link Rect: 198, 469, 216, 476 Flags: Print Destination: 597 Annotation: Subtype: Link Rect: 205, 469, 224, 476 Flags: Print Destination: 597 Annotation: Subtype: Link Rect: 213, 469, 232, 476 Flags: Print Destination: 1 Annotation: Subtype: Link Rect: 220, 469, 239, 476 Flags: Print Destination: 1 Annotation: Subtype: Link Rect: 330, 469, 348, 476 Flags: Print Destination: 1 Annotation: Subtype: Link Rect: 337, 469, 356, 476 Flags: Print Destination: 1 Annotation: Subtype: Link Rect: 344, 469, 363, 476 Flags: Print Destination: 1 Annotation: Subtype: Link Rect: 452, 469, 471, 476 Flags: Print Destination: 597 Annotation: Subtype: Link Rect: 459, 469, 478, 476 Flags: Print Destination: 1 Annotation: Subtype: Link Rect: 163, 455, 182, 462 Flags: Print Destination: 1 Annotation: Subtype: Link Rect: 169, 455, 187, 462 Flags: Print Destination: 1 Annotation: Subtype: Link Rect: 179, 455, 197, 462 Flags: Print Destination: 1 Annotation: Subtype: Link Rect: 286, 455, 305, 462 Flags: Print Destination: 1 Annotation: Subtype: Link Rect: 394, 455, 413, 462 Flags: Print Destination: 597 Annotation: Subtype: Link Rect: 401, 455, 420, 462 Flags: Print Destination: 1 Annotation: Subtype: Link Rect: 503, 455, 522, 462 Flags: Print Destination: 597 Annotation: Subtype: Link Rect: 511, 455, 530, 462 Flags: Print Destination: 597 Annotation: Subtype: Link Rect: 227, 441, 246, 448 Flags: Print Destination: 597 Annotation: Subtype: Link Rect: 235, 441, 254, 448 Flags: Print Destination: 597 Annotation: Subtype: Link Rect: 243, 441, 262, 448 Flags: Print Destination: 1 Annotation: Subtype: Link Rect: 250, 441, 269, 448 Flags: Print Destination: 597 Annotation: Subtype: Link Rect: 376, 441, 395, 448 Flags: Print Destination: 597 Annotation: Subtype: Link Rect: 383, 441, 402, 448 Flags: Print Destination: 1 Annotation: Subtype: Link Rect: 396, 441, 415, 448 Flags: Print Destination: 1 Annotation: Subtype: Link Rect: 408, 441, 427, 448 Flags: Print Destination: 597 Annotation: Subtype: Link Rect: 416, 441, 434, 448 Flags: Print Destination: 597 Annotation: Subtype: Link Rect: 161, 162, 248, 168 Flags: Print Annotation: Subtype: Link Rect: 91, 130, 270, 136 Flags: Print Annotation: Subtype: Link Rect: 561, 120, 587, 126 Flags: Print Annotation: Subtype: Link Rect: 91, 111, 157, 116 Flags: Print Annotation: Subtype: Link Rect: 157, 111, 172, 116 Flags: Print Annotation: Subtype: Link Rect: 172, 111, 204, 116 Flags: Print Annotation: Subtype: Link Rect: 204, 111, 216, 116 Flags: Print Annotation: Subtype: Link Rect: 216, 111, 227, 115 Flags: Print Annotation: Subtype: Link Rect: 227, 111, 240, 116 Flags: Print Annotation: Subtype: Link Rect: 240, 111, 247, 116 Flags: Print Annotation: Subtype: Link Rect: 247, 111, 255, 116 Flags: Print Annotation: Subtype: Link Rect: 255, 111, 255, 111 Flags: Print Page: Label: 2 Annotations: Annotation: Subtype: Link Rect: 327, 367, 355, 374 Flags: Print Annotation: Subtype: Link Rect: 355, 367, 425, 373 Flags: Print Annotation: Subtype: Link Rect: 425, 367, 441, 373 Flags: Print Annotation: Subtype: Link Rect: 441, 367, 475, 374 Flags: Print Annotation: Subtype: Link Rect: 475, 367, 487, 374 Flags: Print Annotation: Subtype: Link Rect: 487, 367, 499, 372 Flags: Print Annotation: Subtype: Link Rect: 499, 367, 513, 374 Flags: Print Annotation: Subtype: Link Rect: 513, 367, 521, 373 Flags: Print Annotation: Subtype: Link Rect: 521, 367, 529, 373 Flags: Print Annotation: Subtype: Link Rect: 529, 367, 529, 367 Flags: Print Annotation: Subtype: Link Rect: 324, 232, 352, 239 Flags: Print Annotation: Subtype: Link Rect: 352, 232, 422, 239 Flags: Print Annotation: Subtype: Link Rect: 422, 232, 438, 239 Flags: Print Annotation: Subtype: Link Rect: 438, 232, 473, 239 Flags: Print Annotation: Subtype: Link Rect: 473, 232, 485, 239 Flags: Print Annotation: Subtype: Link Rect: 485, 232, 497, 237 Flags: Print Annotation: Subtype: Link Rect: 497, 232, 510, 239 Flags: Print Annotation: Subtype: Link Rect: 510, 232, 518, 239 Flags: Print Annotation: Subtype: Link Rect: 518, 232, 527, 239 Flags: Print Annotation: Subtype: Link Rect: 527, 232, 527, 232 Flags: Print Annotation: Subtype: Link Rect: 300, 116, 308, 124 Flags: Print Destination: 135 Page: Label: 3 Annotations: Annotation: Subtype: Link Rect: 153, 746, 162, 753 Flags: Print Destination: 135 Annotation: Subtype: Link Rect: 279, 713, 288, 720 Flags: Print Destination: 135 Annotation: Subtype: Link Rect: 248, 680, 256, 687 Flags: Print Destination: 135 Annotation: Subtype: Link Rect: 259, 636, 268, 644 Flags: Print Destination: 135 Annotation: Subtype: Link Rect: 327, 636, 335, 644 Flags: Print Destination: 135 Annotation: Subtype: Link Rect: 203, 625, 211, 633 Flags: Print Destination: 135 Annotation: Subtype: Link Rect: 120, 521, 129, 528 Flags: Print Destination: 135 Annotation: Subtype: Link Rect: 327, 499, 335, 507 Flags: Print Destination: 135 Annotation: Subtype: Link Rect: 147, 356, 159, 364 Flags: Print Destination: 135 Annotation: Subtype: Link Rect: 164, 324, 176, 331 Flags: Print Destination: 135 Annotation: Subtype: Link Rect: 223, 208, 235, 216 Flags: Print Destination: 135 Annotation: Subtype: Link Rect: 295, 143, 315, 150 Flags: Print Destination: 135 Annotation: Subtype: Link Rect: 515, 757, 535, 764 Flags: Print Destination: 157 Annotation: Subtype: Link Rect: 412, 647, 424, 654 Flags: Print Destination: 157 Annotation: Subtype: Link Rect: 432, 526, 454, 534 Flags: Print Destination: 157 Annotation: Subtype: Link Rect: 566, 364, 577, 371 Flags: Print Destination: 157 Annotation: Subtype: Link Rect: 423, 265, 435, 273 Flags: Print Destination: 157 Annotation: Subtype: Link Rect: 424, 123, 436, 130 Flags: Print Destination: 157 Page: Label: 4 Annotations: Annotation: Subtype: Link Rect: 249, 722, 258, 730 Flags: Print Destination: 135 Annotation: Subtype: Link Rect: 238, 656, 250, 664 Flags: Print Destination: 157 Annotation: Subtype: Link Rect: 323, 623, 335, 631 Flags: Print Destination: 157 Annotation: Subtype: Link Rect: 115, 558, 135, 565 Flags: Print Destination: 157 Annotation: Subtype: Link Rect: 136, 342, 148, 349 Flags: Print Destination: 157 Annotation: Subtype: Link Rect: 323, 276, 335, 284 Flags: Print Destination: 157 Annotation: Subtype: Link Rect: 315, 221, 335, 229 Flags: Print Destination: 157 Annotation: Subtype: Link Rect: 166, 177, 187, 185 Flags: Print Destination: 157 Annotation: Subtype: Link Rect: 205, 145, 216, 152 Flags: Print Destination: 157 Annotation: Subtype: Link Rect: 142, 112, 154, 119 Flags: Print Destination: 157 Annotation: Subtype: Link Rect: 284, 112, 296, 119 Flags: Print Destination: 157 Annotation: Subtype: Link Rect: 575, 677, 587, 685 Flags: Print Destination: 157 Annotation: Subtype: Link Rect: 550, 644, 562, 652 Flags: Print Destination: 157 Annotation: Subtype: Link Rect: 580, 513, 592, 520 Flags: Print Destination: 157 Annotation: Subtype: Link Rect: 471, 480, 483, 488 Flags: Print Destination: 157 Annotation: Subtype: Link Rect: 502, 274, 514, 282 Flags: Print Destination: 157 Annotation: Subtype: Link Rect: 529, 219, 540, 227 Flags: Print Destination: 157 Annotation: Subtype: Link Rect: 571, 154, 582, 161 Flags: Print Destination: 157 Page: Label: 5 Annotations: Annotation: Subtype: Link Rect: 209, 702, 221, 709 Flags: Print Destination: 157 Annotation: Subtype: Link Rect: 306, 669, 318, 676 Flags: Print Destination: 157 Annotation: Subtype: Link Rect: 317, 581, 329, 589 Flags: Print Destination: 157 Annotation: Subtype: Link Rect: 323, 506, 335, 514 Flags: Print Destination: 233 Annotation: Subtype: Link Rect: 133, 463, 145, 470 Flags: Print Destination: 233 Annotation: Subtype: Link Rect: 289, 452, 301, 459 Flags: Print Destination: 233 Annotation: Subtype: Link Rect: 224, 375, 236, 383 Flags: Print Destination: 233 Annotation: Subtype: Link Rect: 116, 342, 127, 350 Flags: Print Destination: 233 Annotation: Subtype: Link Rect: 135, 298, 146, 306 Flags: Print Destination: 233 Annotation: Subtype: Link Rect: 254, 176, 266, 183 Flags: Print Destination: 233 Annotation: Subtype: Link Rect: 423, 757, 435, 764 Flags: Print Destination: 233 Annotation: Subtype: Link Rect: 450, 724, 462, 731 Flags: Print Destination: 233 Annotation: Subtype: Link Rect: 447, 587, 459, 594 Flags: Print Destination: 233 Annotation: Subtype: Link Rect: 580, 587, 592, 594 Flags: Print Destination: 233 Annotation: Subtype: Link Rect: 552, 576, 564, 583 Flags: Print Destination: 233 Annotation: Subtype: Link Rect: 412, 477, 423, 485 Flags: Print Destination: 233 Annotation: Subtype: Link Rect: 380, 433, 392, 441 Flags: Print Destination: 233 Annotation: Subtype: Link Rect: 580, 411, 592, 419 Flags: Print Destination: 233 Annotation: Subtype: Link Rect: 580, 219, 592, 227 Flags: Print Destination: 233 Annotation: Subtype: Link Rect: 372, 132, 383, 139 Flags: Print Destination: 233 Page: Label: 6 Annotations: Annotation: Subtype: Link Rect: 126, 735, 138, 742 Flags: Print Destination: 233 Annotation: Subtype: Link Rect: 144, 555, 156, 562 Flags: Print Destination: 233 Annotation: Subtype: Link Rect: 175, 500, 196, 508 Flags: Print Destination: 233 Annotation: Subtype: Link Rect: 255, 369, 275, 376 Flags: Print Destination: 233 Annotation: Subtype: Link Rect: 275, 165, 286, 172 Flags: Print Destination: 233 Annotation: Subtype: Link Rect: 508, 757, 519, 764 Flags: Print Destination: 233 Annotation: Subtype: Link Rect: 463, 669, 475, 676 Flags: Print Destination: 233 Annotation: Subtype: Link Rect: 455, 543, 466, 551 Flags: Print Destination: 233 Annotation: Subtype: Link Rect: 529, 445, 541, 452 Flags: Print Destination: 233 Annotation: Subtype: Link Rect: 418, 401, 430, 408 Flags: Print Destination: 233 Annotation: Subtype: Link Rect: 438, 208, 450, 216 Flags: Print Destination: 233 Annotation: Subtype: Link Rect: 512, 176, 523, 183 Flags: Print Destination: 233 Annotation: Subtype: Link Rect: 580, 132, 592, 139 Flags: Print Destination: 233 Page: Label: 7 Annotations: Annotation: Subtype: Link Rect: 215, 713, 226, 720 Flags: Print Destination: 233 Annotation: Subtype: Link Rect: 323, 691, 335, 698 Flags: Print Destination: 233 Annotation: Subtype: Link Rect: 211, 504, 223, 512 Flags: Print Destination: 309 Annotation: Subtype: Link Rect: 271, 482, 282, 490 Flags: Print Destination: 309 Annotation: Subtype: Link Rect: 323, 482, 335, 490 Flags: Print Destination: 309 Annotation: Subtype: Link Rect: 194, 439, 206, 446 Flags: Print Destination: 309 Annotation: Subtype: Link Rect: 251, 384, 262, 391 Flags: Print Destination: 309 Annotation: Subtype: Link Rect: 160, 285, 171, 293 Flags: Print Destination: 309 Annotation: Subtype: Link Rect: 264, 252, 275, 260 Flags: Print Destination: 309 Annotation: Subtype: Link Rect: 137, 241, 149, 249 Flags: Print Destination: 309 Annotation: Subtype: Link Rect: 222, 241, 233, 249 Flags: Print Destination: 309 Annotation: Subtype: Link Rect: 197, 208, 209, 216 Flags: Print Destination: 309 Annotation: Subtype: Link Rect: 323, 154, 335, 161 Flags: Print Destination: 309 Annotation: Subtype: Link Rect: 392, 767, 412, 775 Flags: Print Destination: 309 Annotation: Subtype: Link Rect: 406, 621, 418, 628 Flags: Print Destination: 309 Annotation: Subtype: Link Rect: 580, 511, 592, 519 Flags: Print Destination: 309 Annotation: Subtype: Link Rect: 417, 467, 429, 475 Flags: Print Destination: 309 Annotation: Subtype: Link Rect: 521, 445, 533, 453 Flags: Print Destination: 309 Annotation: Subtype: Link Rect: 493, 390, 505, 398 Flags: Print Destination: 309 Annotation: Subtype: Link Rect: 486, 347, 498, 354 Flags: Print Destination: 309 Annotation: Subtype: Link Rect: 532, 189, 543, 196 Flags: Print Destination: 309 Annotation: Subtype: Link Rect: 522, 123, 534, 130 Flags: Print Destination: 309 Page: Label: 8 Annotations: Annotation: Subtype: Link Rect: 169, 713, 189, 720 Flags: Print Destination: 309 Annotation: Subtype: Link Rect: 237, 647, 249, 655 Flags: Print Destination: 309 Annotation: Subtype: Link Rect: 143, 533, 155, 541 Flags: Print Destination: 309 Annotation: Subtype: Link Rect: 266, 468, 277, 475 Flags: Print Destination: 309 Annotation: Subtype: Link Rect: 251, 391, 262, 398 Flags: Print Destination: 309 Annotation: Subtype: Link Rect: 362, 715, 530, 721 Flags: Print Annotation: Subtype: Link Rect: 362, 655, 530, 661 Flags: Print Annotation: Subtype: Link Rect: 362, 615, 519, 621 Flags: Print Annotation: Subtype: Link Rect: 362, 565, 530, 571 Flags: Print Annotation: Subtype: Link Rect: 362, 506, 526, 511 Flags: Print Annotation: Subtype: Link Rect: 362, 456, 497, 462 Flags: Print Annotation: Subtype: Link Rect: 362, 396, 496, 402 Flags: Print Annotation: Subtype: Link Rect: 362, 366, 543, 372 Flags: Print Annotation: Subtype: Link Rect: 362, 336, 532, 342 Flags: Print Annotation: Subtype: Link Rect: 362, 296, 530, 302 Flags: Print Annotation: Subtype: Link Rect: 362, 256, 543, 262 Flags: Print Annotation: Subtype: Link Rect: 424, 217, 561, 223 Flags: Print Annotation: Subtype: Link Rect: 362, 167, 540, 173 Flags: Print Annotation: Subtype: Link Rect: 362, 127, 532, 133 Flags: Print Page: Label: 9 Annotations: Annotation: Subtype: Link Rect: 163, 739, 327, 744 Flags: Print Annotation: Subtype: Link Rect: 105, 679, 273, 685 Flags: Print Annotation: Subtype: Link Rect: 106, 669, 114, 675 Annotation: Subtype: Link Rect: 118, 669, 147, 675 Annotation: Subtype: Link Rect: 151, 667, 157, 675 Annotation: Subtype: Link Rect: 162, 669, 181, 675 Annotation: Subtype: Link Rect: 185, 667, 191, 675 Annotation: Subtype: Link Rect: 196, 669, 226, 675 Annotation: Subtype: Link Rect: 225, 669, 236, 673 Annotation: Subtype: Link Rect: 240, 667, 247, 675 Annotation: Subtype: Link Rect: 252, 669, 256, 675 Annotation: Subtype: Link Rect: 256, 667, 286, 675 Annotation: Subtype: Link Rect: 289, 669, 294, 675 Annotation: Subtype: Link Rect: 293, 667, 295, 670 Annotation: Subtype: Link Rect: 299, 667, 319, 675 Annotation: Subtype: Link Rect: 323, 667, 329, 675 Annotation: Subtype: Link Rect: 106, 659, 131, 665 Annotation: Subtype: Link Rect: 134, 659, 142, 665 Annotation: Subtype: Link Rect: 147, 657, 172, 665 Annotation: Subtype: Link Rect: 172, 659, 173, 660 Annotation: Subtype: Link Rect: 178, 659, 202, 665 Annotation: Subtype: Link Rect: 205, 659, 214, 665 Annotation: Subtype: Link Rect: 218, 661, 220, 662 Annotation: Subtype: Link Rect: 219, 661, 221, 662 Annotation: Subtype: Link Rect: 220, 661, 222, 662 Annotation: Subtype: Link Rect: 226, 657, 258, 665 Annotation: Subtype: Link Rect: 261, 659, 296, 663 Annotation: Subtype: Link Rect: 299, 659, 305, 665 Annotation: Subtype: Link Rect: 309, 657, 330, 665 Annotation: Subtype: Link Rect: 106, 647, 154, 655 Annotation: Subtype: Link Rect: 159, 647, 181, 654 Annotation: Subtype: Link Rect: 185, 649, 192, 655 Annotation: Subtype: Link Rect: 196, 649, 207, 655 Annotation: Subtype: Link Rect: 212, 649, 236, 655 Annotation: Subtype: Link Rect: 240, 649, 249, 655 Annotation: Subtype: Link Rect: 254, 649, 289, 655 Annotation: Subtype: Link Rect: 293, 649, 300, 655 Annotation: Subtype: Link Rect: 300, 647, 329, 655 Annotation: Subtype: Link Rect: 106, 637, 150, 645 Annotation: Subtype: Link Rect: 155, 639, 171, 643 Annotation: Subtype: Link Rect: 176, 639, 181, 645 Annotation: Subtype: Link Rect: 187, 637, 208, 645 Annotation: Subtype: Link Rect: 213, 637, 261, 645 Annotation: Subtype: Link Rect: 267, 639, 270, 645 Annotation: Subtype: Link Rect: 276, 637, 305, 645 Annotation: Subtype: Link Rect: 311, 639, 329, 645 Annotation: Subtype: Link Rect: 106, 627, 190, 635 Annotation: Subtype: Link Rect: 105, 579, 309, 585 Flags: Print Annotation: Subtype: Link Rect: 105, 539, 273, 545 Flags: Print Annotation: Subtype: Link Rect: 105, 499, 273, 505 Flags: Print Annotation: Subtype: Link Rect: 105, 460, 273, 466 Flags: Print Annotation: Subtype: Link Rect: 105, 420, 275, 426 Flags: Print Annotation: Subtype: Link Rect: 105, 380, 276, 386 Flags: Print Annotation: Subtype: Link Rect: 105, 350, 271, 356 Flags: Print Annotation: Subtype: Link Rect: 105, 310, 273, 316 Flags: Print Annotation: Subtype: Link Rect: 105, 260, 279, 266 Flags: Print Annotation: Subtype: Link Rect: 105, 221, 242, 226 Flags: Print Annotation: Subtype: Link Rect: 105, 191, 249, 197 Flags: Print Annotation: Subtype: Link Rect: 263, 161, 330, 167 Flags: Print Annotation: Subtype: Link Rect: 105, 151, 208, 157 Flags: Print Annotation: Subtype: Link Rect: 362, 739, 509, 744 Flags: Print Annotation: Subtype: Link Rect: 362, 709, 530, 715 Flags: Print Annotation: Subtype: Link Rect: 362, 659, 530, 665 Flags: Print Annotation: Subtype: Link Rect: 362, 619, 566, 625 Flags: Print Annotation: Subtype: Link Rect: 362, 569, 547, 575 Flags: Print Annotation: Subtype: Link Rect: 362, 519, 512, 525 Flags: Print Annotation: Subtype: Link Rect: 362, 480, 533, 485 Flags: Print Annotation: Subtype: Link Rect: 362, 440, 528, 446 Flags: Print Annotation: Subtype: Link Rect: 362, 390, 499, 396 Flags: Print Annotation: Subtype: Link Rect: 362, 340, 530, 346 Flags: Print Annotation: Subtype: Link Rect: 362, 270, 530, 276 Flags: Print Annotation: Subtype: Link Rect: 362, 230, 531, 236 Flags: Print Annotation: Subtype: Link Rect: 362, 161, 530, 167 Flags: Print Page: Label: 10 Annotations: Annotation: Subtype: Link Rect: 105, 749, 288, 754 Flags: Print Annotation: Subtype: Link Rect: 105, 709, 275, 715 Flags: Print Annotation: Subtype: Link Rect: 105, 659, 273, 665 Flags: Print Annotation: Subtype: Link Rect: 105, 619, 271, 625 Flags: Print Annotation: Subtype: Link Rect: 105, 579, 275, 585 Flags: Print Annotation: Subtype: Link Rect: 105, 529, 273, 535 Flags: Print Annotation: Subtype: Link Rect: 105, 499, 265, 505 Flags: Print Annotation: Subtype: Link Rect: 105, 460, 275, 466 Flags: Print Annotation: Subtype: Link Rect: 105, 420, 275, 426 Flags: Print Annotation: Subtype: Link Rect: 105, 370, 275, 376 Flags: Print Annotation: Subtype: Link Rect: 105, 320, 269, 326 Flags: Print Annotation: Subtype: Link Rect: 105, 260, 275, 266 Flags: Print Annotation: Subtype: Link Rect: 105, 211, 275, 216 Flags: Print Annotation: Subtype: Link Rect: 231, 181, 330, 187 Flags: Print Annotation: Subtype: Link Rect: 105, 171, 172, 177 Flags: Print Annotation: Subtype: Link Rect: 106, 161, 133, 167 Annotation: Subtype: Link Rect: 137, 159, 142, 166 Annotation: Subtype: Link Rect: 145, 161, 150, 166 Annotation: Subtype: Link Rect: 150, 161, 166, 167 Annotation: Subtype: Link Rect: 169, 159, 172, 166 Annotation: Subtype: Link Rect: 175, 161, 207, 167 Annotation: Subtype: Link Rect: 210, 159, 221, 167 Annotation: Subtype: Link Rect: 224, 161, 250, 167 Annotation: Subtype: Link Rect: 252, 159, 264, 166 Annotation: Subtype: Link Rect: 267, 161, 286, 167 Annotation: Subtype: Link Rect: 289, 159, 296, 166 Annotation: Subtype: Link Rect: 299, 159, 330, 167 Annotation: Subtype: Link Rect: 106, 151, 110, 157 Annotation: Subtype: Link Rect: 109, 149, 110, 152 Annotation: Subtype: Link Rect: 114, 151, 121, 156 Annotation: Subtype: Link Rect: 123, 151, 132, 157 Annotation: Subtype: Link Rect: 135, 151, 169, 157 Annotation: Subtype: Link Rect: 172, 151, 214, 157 Annotation: Subtype: Link Rect: 217, 151, 224, 157 Annotation: Subtype: Link Rect: 226, 151, 239, 157 Annotation: Subtype: Link Rect: 241, 151, 264, 157 Annotation: Subtype: Link Rect: 267, 151, 330, 157 Annotation: Subtype: Link Rect: 106, 141, 113, 147 Annotation: Subtype: Link Rect: 115, 141, 127, 147 Annotation: Subtype: Link Rect: 130, 141, 178, 147 Annotation: Subtype: Link Rect: 181, 141, 219, 147 Annotation: Subtype: Link Rect: 222, 141, 230, 145 Annotation: Subtype: Link Rect: 233, 141, 246, 147 Annotation: Subtype: Link Rect: 249, 141, 268, 147 Annotation: Subtype: Link Rect: 271, 141, 290, 147 Annotation: Subtype: Link Rect: 293, 141, 307, 147 Annotation: Subtype: Link Rect: 310, 141, 330, 147 Annotation: Subtype: Link Rect: 106, 131, 126, 137 Annotation: Subtype: Link Rect: 126, 131, 127, 132 Annotation: Subtype: Link Rect: 130, 129, 160, 137 Annotation: Subtype: Link Rect: 161, 131, 173, 137 Annotation: Subtype: Link Rect: 174, 133, 176, 134 Annotation: Subtype: Link Rect: 175, 133, 177, 134 Annotation: Subtype: Link Rect: 176, 133, 178, 134 Annotation: Subtype: Link Rect: 179, 131, 190, 137 Annotation: Subtype: Link Rect: 192, 131, 193, 132 Annotation: Subtype: Link Rect: 362, 759, 510, 764 Flags: Print Annotation: Subtype: Link Rect: 362, 719, 532, 725 Flags: Print Annotation: Subtype: Link Rect: 362, 689, 531, 695 Flags: Print Annotation: Subtype: Link Rect: 362, 639, 543, 645 Flags: Print Annotation: Subtype: Link Rect: 411, 599, 581, 605 Flags: Print Annotation: Subtype: Link Rect: 362, 559, 499, 565 Flags: Print Annotation: Subtype: Link Rect: 362, 529, 543, 535 Flags: Print Annotation: Subtype: Link Rect: 362, 499, 530, 505 Flags: Print Annotation: Subtype: Link Rect: 362, 460, 530, 466 Flags: Print Annotation: Subtype: Link Rect: 454, 430, 584, 436 Flags: Print Annotation: Subtype: Link Rect: 362, 400, 564, 406 Flags: Print Annotation: Subtype: Link Rect: 362, 350, 530, 356 Flags: Print Annotation: Subtype: Link Rect: 362, 300, 532, 306 Flags: Print Annotation: Subtype: Link Rect: 362, 270, 531, 276 Flags: Print Annotation: Subtype: Link Rect: 362, 221, 493, 226 Flags: Print Annotation: Subtype: Link Rect: 362, 181, 528, 187 Flags: Print Annotation: Subtype: Link Rect: 362, 131, 532, 137 Flags: Print Page: Label: 11 Annotations: Annotation: Subtype: Link Rect: 105, 739, 300, 744 Flags: Print Annotation: Subtype: Link Rect: 163, 699, 299, 705 Flags: Print Annotation: Subtype: Link Rect: 105, 649, 241, 655 Flags: Print Annotation: Subtype: Link Rect: 105, 609, 240, 615 Flags: Print Annotation: Subtype: Link Rect: 105, 559, 241, 565 Flags: Print Annotation: Subtype: Link Rect: 105, 519, 229, 525 Flags: Print Annotation: Subtype: Link Rect: 105, 490, 274, 495 Flags: Print Annotation: Subtype: Link Rect: 105, 450, 288, 456 Flags: Print Annotation: Subtype: Link Rect: 105, 410, 275, 416 Flags: Print Annotation: Subtype: Link Rect: 105, 360, 242, 366 Flags: Print Annotation: Subtype: Link Rect: 105, 300, 242, 306 Flags: Print Annotation: Subtype: Link Rect: 252, 270, 330, 276 Flags: Print Annotation: Subtype: Link Rect: 105, 260, 193, 266 Flags: Print Annotation: Subtype: Link Rect: 419, 759, 584, 764 Flags: Print Annotation: Subtype: Link Rect: 362, 729, 533, 735 Flags: Print Annotation: Subtype: Link Rect: 362, 689, 509, 695 Flags: Print Annotation: Subtype: Link Rect: 362, 649, 499, 655 Flags: Print Annotation: Subtype: Link Rect: 362, 609, 499, 615 Flags: Print Annotation: Subtype: Link Rect: 362, 569, 530, 575 Flags: Print Annotation: Subtype: Link Rect: 362, 519, 538, 525 Flags: Print Annotation: Subtype: Link Rect: 362, 480, 499, 485 Flags: Print Annotation: Subtype: Link Rect: 362, 430, 507, 436 Flags: Print Annotation: Subtype: Link Rect: 362, 390, 528, 396 Flags: Print Annotation: Subtype: Link Rect: 362, 340, 540, 346 Flags: Print Annotation: Subtype: Link Rect: 362, 290, 499, 296 Flags: Print Checksum: 7dfaf361 Type: CRC32 Checksum: 2f0c4a1164998707c6eac803a6cb7b5d Type: MD5 Checksum: ce560310f90b12c1ad53daad15d7c2df5826d06b Type: SHA-1