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Kovanen and Joan Carles Escola-Gil Creator: LaTeX with hyperref package + hypdvips Producer: dvips + MiKTeX GPL Ghostscript 9.0 CreationDate: Mon Feb 7 10:45:49 2022 CET ModDate: Mon Feb 7 14:14:53 2022 CET Tagged: no UserProperties: no Suspects: no Form: none JavaScript: no Pages: 16 Encrypted: no Page size: 595.26 x 779.52 pts Page rot: 0 File size: 631725 bytes Optimized: no PDF version: 1.6 name type encoding emb sub uni object ID ------------------------------------ ----------------- ---------------- --- --- --- --------- PIAOFJ+HelveticaNeueLTStd-BdIt Type 1C WinAnsi yes yes no 40 0 MYBPOG+HelveticaNeueLTStd-LtIt Type 1C Custom yes yes no 42 0 PZNHJI+HelveticaNeueLTStd-MdIt Type 1C WinAnsi yes yes no 48 0 NTKWNU+MinionPro-Regular Type 1C Custom yes yes no 50 0 FEHWTR+HelveticaNeueLTStd-Bd Type 1C Custom yes yes no 22 0 PLHAKI+HelveticaNeueLTStd-Lt Type 1C Custom yes yes no 27 0 CPXOGE+MinionPro-It Type 1C Custom yes yes no 69 0 IDISLB+MinionPro-Bold Type 1C Custom yes yes no 74 0 QKTCQK+MTSY Type 1C Custom yes yes no 132 0 QASLBY+MTGU Type 1C Custom yes yes no 273 0 Jhove (Rel. 1.22.1, 2019-04-17) Date: 2023-10-10 02:23:12 CEST RepresentationInformation: 282319.pdf ReportingModule: PDF-hul, Rel. 1.12.1 (2019-04-17) LastModified: 2023-10-09 13:00:42 CEST Size: 631725 Format: PDF Version: 1.6 Status: Well-Formed and valid SignatureMatches: PDF-hul MIMEtype: application/pdf PDFMetadata: Objects: 608 FreeObjects: 21 IncrementalUpdates: 0 DocumentCatalog: ViewerPreferences: HideToolbar: false HideMenubar: false HideWindowUI: false FitWindow: true CenterWindow: false DisplayDocTitle: false NonFullScreenPageMode: UseNone Direction: L2R ViewArea: CropBox ViewClip: CropBox PrintArea: CropBox PageClip: CropBox PageLayout: SinglePage PageMode: UseOutlines Language: en Outlines: Item: Title: Lipid-Laden Macrophages and Inflammation in Atherosclerosis and Cancer: An Integrative View Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@eafc191 Children: Item: Title: Introduction Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@612fc6eb Item: Title: Macrophages in Atherogenesis: Ontogeny, Cholesterol Loading, Polarization, and Functional Phenotypes Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@1060b431 Item: Title: Macrophages in Tumor Development: Ontogeny, Polarization, Pro- and Anti-Tumoral Macrophages Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@612679d6 Item: Title: Extracellular Microenvironments Within an Atheroma and a Tumor: Solutes Derived from the Blood and the Local Cells Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@11758f2a Item: Title: Lipid-Laden TAMs are not Cholesterol-Loaded Foam Cells Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@e720b71 Item: Title: Concluding Remarks Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@1b26f7b2 Item: Title: Author Contributions Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@491cc5c9 Item: Title: Funding Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@74ad1f1f Item: Title: References Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@6a1aab78 Info: Title: Lipid-Laden Macrophages and Inflammation in Atherosclerosis and Cancer: An Integrative View Author: Petri T. Kovanen and Joan Carles Escola-Gil Subject: Atherosclerotic arterial plaques and malignant solid tumors contain macrophages, which participate in anaerobic metabolism, acidosis, and inflammatory processes inherent in the development of either disease. 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Petri T. 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Destination: External Annotation: Subtype: Link Rect: 43, 30, 154, 38 Annotation: Subtype: Link Rect: 157, 29, 217, 37 Annotation: Subtype: Link Rect: 423, 29, 551, 38 Page: Label: 11 Sequence: 11 Annotations: Annotation: Subtype: Link Rect: 205, 671, 211, 681 Destination: External Annotation: Subtype: Link Rect: 213, 671, 223, 681 Destination: External Annotation: Subtype: Link Rect: 224, 671, 234, 681 Destination: External Annotation: Subtype: Link Rect: 236, 671, 246, 681 Destination: External Annotation: Subtype: Link Rect: 248, 671, 258, 681 Destination: External Annotation: Subtype: Link Rect: 415, 671, 425, 681 Destination: External Annotation: Subtype: Link Rect: 427, 671, 437, 681 Destination: External Annotation: Subtype: Link Rect: 438, 671, 448, 681 Destination: External Annotation: Subtype: Link Rect: 258, 650, 268, 659 Destination: External Annotation: Subtype: Link Rect: 434, 659, 443, 669 Destination: External Annotation: Subtype: Link Rect: 498, 650, 507, 659 Destination: External Annotation: Subtype: Link Rect: 133, 619, 143, 629 Destination: External Annotation: Subtype: Link Rect: 145, 619, 155, 629 Destination: External Annotation: Subtype: Link Rect: 442, 638, 452, 648 Destination: External Annotation: Subtype: Link Rect: 245, 608, 255, 617 Destination: External Annotation: Subtype: Link Rect: 455, 608, 465, 617 Destination: External Annotation: Subtype: Link Rect: 467, 608, 477, 617 Destination: External Annotation: Subtype: Link Rect: 208, 586, 217, 596 Destination: External Annotation: Subtype: Link Rect: 235, 558, 245, 567 Destination: External Annotation: Subtype: Link Rect: 406, 586, 416, 596 Destination: External Annotation: Subtype: Link Rect: 486, 567, 496, 577 Destination: External Annotation: Subtype: Link Rect: 211, 546, 221, 556 Destination: External Annotation: Subtype: Link Rect: 223, 546, 233, 556 Destination: External Annotation: Subtype: Link Rect: 230, 537, 240, 546 Destination: External Annotation: Subtype: Link Rect: 242, 537, 252, 546 Destination: External Annotation: Subtype: Link Rect: 208, 499, 217, 508 Destination: External Annotation: Subtype: Link Rect: 405, 546, 414, 556 Destination: External Annotation: Subtype: Link Rect: 462, 537, 472, 546 Destination: External Annotation: Subtype: Link Rect: 474, 537, 484, 546 Destination: External Annotation: Subtype: Link Rect: 361, 518, 371, 527 Destination: External Annotation: Subtype: Link Rect: 146, 487, 156, 497 Destination: External Annotation: Subtype: Link Rect: 356, 487, 366, 497 Destination: External Annotation: Subtype: Link Rect: 368, 487, 378, 497 Destination: External Annotation: Subtype: Link Rect: 212, 475, 226, 485 Destination: External Annotation: Subtype: Link Rect: 406, 475, 419, 485 Destination: External Annotation: Subtype: Link Rect: 166, 445, 175, 454 Destination: External Annotation: Subtype: Link Rect: 177, 445, 187, 454 Destination: External Annotation: Subtype: Link Rect: 133, 426, 143, 435 Destination: External Annotation: Subtype: Link Rect: 145, 426, 155, 435 Destination: External Annotation: Subtype: Link Rect: 157, 426, 166, 435 Destination: External Annotation: Subtype: Link Rect: 522, 454, 535, 464 Destination: External Annotation: Subtype: Link Rect: 366, 435, 380, 445 Destination: External Annotation: Subtype: Link Rect: 309, 395, 319, 405 Destination: External Annotation: Subtype: Link Rect: 321, 395, 335, 405 Destination: External Annotation: Subtype: Link Rect: 471, 395, 484, 405 Destination: External Annotation: Subtype: Link Rect: 486, 395, 499, 405 Destination: External Annotation: Subtype: Link Rect: 43, 30, 154, 38 Annotation: Subtype: Link Rect: 157, 29, 217, 37 Annotation: Subtype: Link Rect: 423, 29, 551, 38 Page: Label: 12 Sequence: 12 Annotations: Annotation: Subtype: Link Rect: 141, 649, 176, 659 Destination: External Annotation: Subtype: Link Rect: 74, 369, 129, 376 Annotation: Subtype: Link Rect: 292, 338, 60, 358 Annotation: Subtype: Link Rect: 74, 310, 131, 320 Annotation: Subtype: Link Rect: 292, 282, 60, 301 Annotation: Subtype: Link Rect: 74, 246, 158, 253 Annotation: Subtype: Link Rect: 97, 227, 186, 234 Annotation: Subtype: Link Rect: 74, 198, 159, 206 Annotation: Subtype: Link Rect: 164, 178, 237, 187 Annotation: Subtype: Link Rect: 292, 150, 60, 169 Annotation: Subtype: Link Rect: 152, 130, 235, 139 Annotation: Subtype: Link Rect: 74, 93, 158, 102 Annotation: Subtype: Link Rect: 164, 74, 233, 83 Annotation: Subtype: Link Rect: 552, 377, 320, 396 Annotation: Subtype: Link Rect: 552, 349, 320, 367 Annotation: Subtype: Link Rect: 410, 331, 487, 338 Annotation: Subtype: Link Rect: 334, 302, 411, 310 Annotation: Subtype: Link Rect: 390, 264, 507, 272 Annotation: Subtype: Link Rect: 403, 244, 499, 253 Annotation: Subtype: Link Rect: 490, 227, 541, 234 Annotation: Subtype: Link Rect: 334, 178, 414, 187 Annotation: Subtype: Link Rect: 334, 151, 423, 158 Annotation: Subtype: Link Rect: 424, 113, 508, 121 Annotation: Subtype: Link Rect: 334, 75, 436, 83 Annotation: Subtype: Link Rect: 43, 29, 154, 37 Annotation: Subtype: Link Rect: 157, 28, 217, 36 Annotation: Subtype: Link Rect: 423, 28, 551, 37 Page: Label: 13 Sequence: 13 Annotations: Annotation: Subtype: Link Rect: 74, 678, 144, 687 Annotation: Subtype: Link Rect: 184, 661, 273, 668 Annotation: Subtype: Link Rect: 171, 632, 256, 640 Annotation: Subtype: Link Rect: 74, 604, 134, 611 Annotation: Subtype: Link Rect: 171, 585, 255, 593 Annotation: Subtype: Link Rect: 74, 547, 177, 554 Annotation: Subtype: Link Rect: 171, 519, 260, 526 Annotation: Subtype: Link Rect: 74, 481, 183, 488 Annotation: Subtype: Link Rect: 204, 462, 289, 470 Annotation: Subtype: Link Rect: 74, 434, 159, 441 Annotation: Subtype: Link Rect: 74, 405, 150, 413 Annotation: Subtype: Link Rect: 74, 367, 140, 375 Annotation: Subtype: Link Rect: 74, 329, 158, 337 Annotation: Subtype: Link Rect: 74, 301, 172, 308 Annotation: Subtype: Link Rect: 133, 281, 212, 290 Annotation: Subtype: Link Rect: 177, 254, 237, 261 Annotation: Subtype: Link Rect: 177, 235, 262, 242 Annotation: Subtype: Link Rect: 219, 214, 281, 224 Annotation: Subtype: Link Rect: 74, 197, 172, 204 Annotation: Subtype: Link Rect: 74, 169, 172, 176 Annotation: Subtype: Link Rect: 108, 131, 158, 138 Annotation: Subtype: Link Rect: 74, 102, 183, 110 Annotation: Subtype: Link Rect: 74, 72, 147, 81 Annotation: Subtype: Link Rect: 334, 680, 423, 687 Annotation: Subtype: Link Rect: 397, 642, 482, 649 Annotation: Subtype: Link Rect: 552, 592, 320, 612 Annotation: Subtype: Link Rect: 334, 566, 443, 573 Annotation: Subtype: Link Rect: 334, 538, 412, 545 Annotation: Subtype: Link Rect: 390, 509, 505, 517 Annotation: Subtype: Link Rect: 445, 481, 544, 488 Annotation: Subtype: Link Rect: 368, 452, 468, 460 Annotation: Subtype: Link Rect: 405, 415, 503, 422 Annotation: Subtype: Link Rect: 334, 375, 422, 384 Annotation: Subtype: Link Rect: 420, 337, 484, 347 Annotation: Subtype: Link Rect: 418, 318, 495, 328 Annotation: Subtype: Link Rect: 552, 290, 320, 309 Annotation: Subtype: Link Rect: 448, 252, 517, 261 Annotation: Subtype: Link Rect: 468, 224, 551, 233 Annotation: Subtype: Link Rect: 334, 186, 398, 195 Annotation: Subtype: Link Rect: 334, 150, 412, 157 Annotation: Subtype: Link Rect: 368, 121, 484, 129 Annotation: Subtype: Link Rect: 368, 93, 436, 100 Annotation: Subtype: Link Rect: 43, 30, 154, 38 Annotation: Subtype: Link Rect: 157, 29, 217, 37 Annotation: Subtype: Link Rect: 423, 29, 551, 38 Page: Label: 14 Sequence: 14 Annotations: Annotation: Subtype: Link Rect: 119, 697, 198, 706 Annotation: Subtype: Link Rect: 108, 661, 162, 668 Annotation: Subtype: Link Rect: 74, 623, 191, 630 Annotation: Subtype: Link Rect: 159, 593, 244, 602 Annotation: Subtype: Link Rect: 74, 557, 162, 564 Annotation: Subtype: Link Rect: 74, 528, 176, 536 Annotation: Subtype: Link Rect: 146, 489, 235, 498 Annotation: Subtype: Link Rect: 74, 460, 140, 469 Annotation: Subtype: Link Rect: 74, 422, 153, 432 Annotation: Subtype: Link Rect: 108, 385, 221, 394 Annotation: Subtype: Link Rect: 150, 348, 259, 356 Annotation: Subtype: Link Rect: 152, 309, 239, 318 Annotation: Subtype: Link Rect: 74, 282, 177, 289 Annotation: Subtype: Link Rect: 292, 243, 60, 262 Annotation: Subtype: Link Rect: 74, 216, 161, 224 Annotation: Subtype: Link Rect: 145, 176, 238, 185 Annotation: Subtype: Link Rect: 129, 150, 205, 157 Annotation: Subtype: Link Rect: 74, 110, 153, 119 Annotation: Subtype: Link Rect: 140, 74, 209, 81 Annotation: Subtype: Link Rect: 334, 678, 412, 687 Annotation: Subtype: Link Rect: 334, 651, 386, 659 Annotation: Subtype: Link Rect: 412, 623, 490, 630 Annotation: Subtype: Link Rect: 334, 593, 407, 602 Annotation: Subtype: Link Rect: 452, 564, 535, 573 Annotation: Subtype: Link Rect: 334, 538, 404, 545 Annotation: Subtype: Link Rect: 368, 498, 449, 507 Annotation: Subtype: Link Rect: 334, 462, 438, 469 Annotation: Subtype: Link Rect: 368, 434, 453, 441 Annotation: Subtype: Link Rect: 400, 404, 490, 413 Annotation: Subtype: Link Rect: 334, 377, 413, 384 Annotation: Subtype: Link Rect: 334, 347, 414, 356 Annotation: Subtype: Link Rect: 334, 318, 421, 328 Annotation: Subtype: Link Rect: 334, 290, 403, 299 Annotation: Subtype: Link Rect: 445, 254, 544, 261 Annotation: Subtype: Link Rect: 334, 225, 394, 233 Annotation: Subtype: Link Rect: 413, 197, 465, 205 Annotation: Subtype: Link Rect: 334, 159, 418, 167 Annotation: Subtype: Link Rect: 399, 129, 467, 138 Annotation: Subtype: Link Rect: 393, 91, 480, 101 Annotation: Subtype: Link Rect: 43, 30, 154, 38 Annotation: Subtype: Link Rect: 157, 29, 217, 37 Annotation: Subtype: Link Rect: 423, 29, 551, 38 Page: Label: 15 Sequence: 15 Annotations: Annotation: Subtype: Link Rect: 292, 696, 60, 716 Annotation: Subtype: Link Rect: 188, 680, 242, 687 Annotation: Subtype: Link Rect: 74, 651, 159, 659 Annotation: Subtype: Link Rect: 292, 622, 60, 641 Annotation: Subtype: Link Rect: 74, 593, 161, 602 Annotation: Subtype: Link Rect: 74, 555, 153, 564 Annotation: Subtype: Link Rect: 292, 518, 60, 537 Annotation: Subtype: Link Rect: 164, 489, 226, 498 Annotation: Subtype: Link Rect: 74, 423, 173, 432 Annotation: Subtype: Link Rect: 74, 385, 165, 394 Annotation: Subtype: Link Rect: 129, 356, 222, 366 Annotation: Subtype: Link Rect: 292, 310, 60, 328 Annotation: Subtype: Link Rect: 74, 262, 187, 271 Annotation: Subtype: Link Rect: 93, 195, 176, 204 Annotation: Subtype: Link Rect: 292, 157, 60, 177 Annotation: Subtype: Link Rect: 74, 120, 153, 129 Annotation: Subtype: Link Rect: 74, 83, 159, 91 Annotation: Subtype: Link Rect: 552, 677, 320, 698 Annotation: Subtype: Link Rect: 334, 640, 416, 649 Annotation: Subtype: Link Rect: 334, 602, 422, 612 Annotation: Subtype: Link Rect: 434, 576, 537, 583 Annotation: Subtype: Link Rect: 552, 478, 320, 499 Annotation: Subtype: Link Rect: 334, 451, 425, 460 Annotation: Subtype: Link Rect: 334, 424, 423, 431 Annotation: Subtype: Link Rect: 334, 396, 423, 403 Annotation: Subtype: Link Rect: 368, 358, 454, 365 Annotation: Subtype: Link Rect: 334, 320, 438, 327 Annotation: Subtype: Link Rect: 454, 292, 511, 299 Annotation: Subtype: Link Rect: 354, 252, 432, 261 Annotation: Subtype: Link Rect: 334, 216, 452, 224 Annotation: Subtype: Link Rect: 334, 178, 437, 186 Annotation: Subtype: Link Rect: 552, 139, 320, 158 Annotation: Subtype: Link Rect: 334, 102, 438, 110 Annotation: Subtype: Link Rect: 431, 82, 518, 91 Annotation: Subtype: Link Rect: 43, 30, 154, 38 Annotation: Subtype: Link Rect: 157, 29, 217, 37 Annotation: Subtype: Link Rect: 423, 29, 551, 38 Page: Label: 16 Sequence: 16 Annotations: Annotation: Subtype: Link Rect: 118, 689, 186, 696 Annotation: Subtype: Link Rect: 104, 650, 187, 659 Annotation: Subtype: Link Rect: 74, 612, 163, 621 Annotation: Subtype: Link Rect: 458, 624, 484, 630 Annotation: Subtype: Link Rect: 484, 624, 516, 630 Annotation: Subtype: Link Rect: 515, 624, 551, 631 Annotation: Subtype: Link Rect: 304, 614, 327, 621 Annotation: Subtype: Link Rect: 327, 613, 354, 622 Annotation: Subtype: Link Rect: 43, 30, 154, 38 Annotation: Subtype: Link Rect: 157, 29, 217, 37 Annotation: Subtype: Link Rect: 423, 29, 551, 38 Checksum: fbdb25e3 Type: CRC32 Checksum: 1ba0fa09e1388509db427d53544ef856 Type: MD5 Checksum: db73c7daf5db8d19c21d6fb62c7cb439ad5adf02 Type: SHA-1