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Jhove (Rel. 1.22.1, 2019-04-17)
 Date: 2023-10-14 02:25:42 CEST
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    Outlines: 
     Item: 
      Title: Endogenous Syngap1 alpha splice forms promote cognitive function and seizure protection
      Children: 
       Item: 
        Title: Editor's evaluation
       Item: 
        Title: Introduction
       Item: 
        Title: Results
        Children: 
         Item: 
          Title: Reduced α1/2 C-terminal isoform expression is associated with enhanced seizure latency and cognitive impairment
         Item: 
          Title: Enhanced α1/2 C-terminal isoform expression is associated with seizure protection and improved cognitive function
         Item: 
          Title: Alpha1 C-terminal isoform function is required for cognitive function and seizure protection
         Item: 
          Title: Alpha1/2 C-terminal isoform expression or function predicts changes in excitatory synapse function
       Item: 
        Title: Discussion
       Item: 
        Title: Materials and methods
        Children: 
         Item: 
          Title: Animals
         Item: 
          Title: Transcriptomics
         Item: 
          Title: Cell culture
          Children: 
           Item: 
            Title: Cell lines
           Item: 
            Title: Primary forebrain cultures
         Item: 
          Title: In situ colocalization assay
         Item: 
          Title: PSD95-SynGAP co-IP assay
         Item: 
          Title: In vitro treatments
         Item: 
          Title: Subcellular fractionation
          Children: 
           Item: 
            Title: From tissue
           Item: 
            Title: From primary culture
         Item: 
          Title: Immunoblotting
         Item: 
          Title: Immunocytochemistry
         Item: 
          Title: PSD95 immunoprecipitation and mass spectrometry
         Item: 
          Title: Hippocampal LTP and extracellular recordings
         Item: 
          Title: Ex vivo whole-cell electrophysiology
         Item: 
          Title: Behavior
          Children: 
           Item: 
            Title: Flurothyl-induced seizures
           Item: 
            Title: Morris water maze
           Item: 
            Title: Open-field test
           Item: 
            Title: Contextual fear conditioning
       Item: 
        Title: Acknowledgements
       Item: 
        Title: Additional information
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         Item: 
          Title: Funding
         Item: 
          Title: Author contributions
         Item: 
          Title: Author ORCIDs
         Item: 
          Title: Ethics
         Item: 
          Title: Decision letter and Author response
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        Title: Additional files
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         Item: 
          Title: Supplementary files
       Item: 
        Title: References
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   Type: MD5
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