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edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bib46' cannot be found Offset: 4532845 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bib35' cannot be found Offset: 4532845 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bib53' cannot be found Offset: 4532845 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bib46' cannot be found Offset: 4532845 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bib46' cannot be found Offset: 4532845 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bib21' 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edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bib63' cannot be found Offset: 4532845 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bib63' cannot be found Offset: 4532845 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bib11' cannot be found Offset: 4532845 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bib54' cannot be found Offset: 4532845 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bib45' cannot be found Offset: 4532845 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bib45' 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edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bib39' cannot be found Offset: 4532845 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bib39' cannot be found Offset: 4532845 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bib45' cannot be found Offset: 4532845 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bib25' cannot be found Offset: 4532845 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bib31' cannot be found Offset: 4532845 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bib31' 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edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bib70' cannot be found Offset: 4532845 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bib14' cannot be found Offset: 4532845 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bib14' cannot be found Offset: 4532845 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bib16' cannot be found Offset: 4532845 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bib47' cannot be found Offset: 4532845 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bib71' 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edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bib15' cannot be found Offset: 4532845 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bib15' cannot be found Offset: 4532845 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bib16' cannot be found Offset: 4532845 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bib47' cannot be found Offset: 4532845 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bib65' cannot be found Offset: 4532845 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bib51' cannot be found Offset: 4532845 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bib52' cannot be found Offset: 4532845 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bib41' cannot be found Offset: 4532845 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bib11' cannot be found Offset: 4532845 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bib19' cannot be found Offset: 4532845 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bib43' cannot be found Offset: 4532845 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bib62' cannot be found Offset: 4532845 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bib18' cannot be found Offset: 4532845 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bib15' cannot be found Offset: 4532845 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bib23' cannot be found Offset: 4532845 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bib23' cannot be found Offset: 4532845 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bib20' cannot be found Offset: 4532845 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bib67' cannot be found Offset: 4532845 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bib37' cannot be found Offset: 4532845 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bib45' cannot be found Offset: 4532845 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bib63' cannot be found Offset: 4532845 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bib11' cannot be found Offset: 4532845 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bib11' cannot be found Offset: 4532845 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bib54' cannot be found Offset: 4532845 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bib54' cannot be found Offset: 4532845 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bib39' cannot be found Offset: 4532845 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bib13' cannot be found Offset: 4532845 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bib47' 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edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'sec4.2.1' cannot be found Offset: 4532845 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bib75' cannot be found Offset: 4532845 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bib51' cannot be found Offset: 4532845 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bib41' cannot be found Offset: 4532845 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bib41' cannot be found Offset: 4532845 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 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FreeObjects: 1 IncrementalUpdates: 1 DocumentCatalog: PageLayout: SinglePage PageMode: UseOutlines Language: en Outlines: Item: Title: MDA-LDL vaccination induces athero-protective germinal-center-derived antibody responses Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@8646db9 Children: Item: Title: Introduction Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@37374a5e Item: Title: Results Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@4671e53b Children: Item: Title: Athero-protective MDA-LDL immunization induces GC reactions Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@2db7a79b Item: Title: SHM and selection in MDA-LDL-immunized mice Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@6950e31 Item: Title: GC-derived PCs are athero-protective Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@b7dd107 Item: Title: GC-derived antibodies contribute to MDA-LDL immunization-mediated athero-protection Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@42eca56e Item: Title: Discussion Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@52f759d7 Children: Item: Title: Limitations of the study Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@7cbd213e Item: Title: Supplemental information Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@192d3247 Item: Title: Acknowledgments Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@3ecd23d9 Item: Title: Author contributions Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@569cfc36 Item: Title: Declaration of interests Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@43bd930a Item: Title: References Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@33723e30 Item: Title: STAR★Methods Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@64f6106c Children: Item: Title: Key resources table 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Item: Title: Flow cytometry Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@4e718207 Item: Title: Bone marrow transfer Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@1d371b2d Item: Title: Single-cell sorting and sequencing of immunoglobulin transcripts Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@543c6f6d Item: Title: Enzyme-linked immunosorbent assay (ELISA) for immunoglobulin detection Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@13eb8acf Item: Title: Quantification of atherosclerosis progression Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@51c8530f Item: Title: Necrotic core analysis Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@7403c468 Item: Title: Immunofluorescence Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@43738a82 Item: Title: Quantification and statistical analysis Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@c81cdd1 Info: Title: MDA-LDL vaccination induces athero-protective germinal-center-derived antibody responses Author: Inmaculada Martos-Folgado Subject: CellReports, 41 (2022) 111468. doi:10.1016/j.celrep.2022.111468 Creator: Elsevier Producer: Acrobat Distiller 8.1.0 (Windows) CreationDate: Fri Oct 07 22:08:10 CEST 2022 ModDate: Sat Oct 08 09:53:38 CEST 2022 ID: 0x1c30d928fd50b48631a73c0233e1c16e, 0x616825d492d0d14fabbeb87bcf2cf92c Filters: FilterPipeline: FlateDecode FilterPipeline: DCTDecode Images: Image: NisoImageMetadata: FormatName: image/jpg CompressionScheme: JPEG ImageWidth: 1191 ImageHeight: 1191 BitsPerSample: 8 BitsPerSampleUnit: integer ColorSpace: ICCBased Image: NisoImageMetadata: FormatName: image/png ImageWidth: 68 ImageHeight: 68 ColorSpace: palette color BitsPerSample: 8 BitsPerSampleUnit: integer Filter: FlateDecode Image: NisoImageMetadata: FormatName: image/png ImageWidth: 68 ImageHeight: 68 ColorSpace: palette 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Busse Pilar Delgado Sonia M. Mur Laura Cobos-Figueroa Joan C. Escolà-Gil Jose L. Martín-Ventura Hedda Wardemann Almudena R. Ramiro B cell antibody atherosclerosis germinal center MDA-LDL vaccine CellReports, 41 (2022) 111468. doi:10.1016/j.celrep.2022.111468 The Authors journal CellReports © 2022 The Authors. 2211-1247 41 2 11 October 2022 2022-10-11 111468 111468 10.1016/j.celrep.2022.111468 https://doi.org/10.1016/j.celrep.2022.111468 2010-04-23 true 10.1016/j.celrep.2022.111468 elsevier.com sciencedirect.com VoR 10.1016/j.celrep.2022.111468 noindex true 2010-04-23 true sciencedirect.com elsevier.com Elsevier 2022-10-08T01:08:10+05:30 2022-10-08T12:53:38+05:30 2022-10-08T12:53:38+05:30 True Acrobat Distiller 8.1.0 (Windows) uuid:c488b42c-2d1a-4870-bb62-a4a4c8862720 uuid:268e3222-e088-4bf8-b286-5bcc7420097a http://creativecommons.org/licenses/by-nc-nd/4.0/ Pages: Page: Label: 1 Annotations: Annotation: Subtype: Link Rect: 354, 503, 430, 513 Annotation: Subtype: Link Rect: 100, 48, 273, 56 Annotation: Subtype: Link Rect: 53, 58, 69, 74 Page: Label: 2 Annotations: Annotation: Subtype: Link Rect: 172, 605, 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