60ffdd11ba1bde0f9aec121406b7591b  284169.pdf
8d08d6892a7c8d32e4e0a23e1f4816e32315eae7  284169.pdf
b018a591d8b902917a8396b08b2065d143fc1a11013b0f7a1b002b2158fc2b2e  284169.pdf

Title:          Water T2 could predict functional decline in patients with dysferlinopathy
Subject:        J cachexia sarcopenia muscle 2022.13:2888-2897
Keywords:       10.1002/jcsm.13063 and Magnetic resonance imaging; Water T2; Limb girdle muscular dystrophy; Limb girdle muscular dystrophy R2; Limb girdle muscular dystrophy 2B
Author:         Ursula Moore, Ericky Caldas de Almeida Araújo, Harmen Reyngoudt, Heather Gordish‐Dressman, Fiona E. Smith, Ian Wilson, Meredith James, Anna Mayhew, Laura Rufibach, John W. Day, Kristi J. Jones, Diana X. Bharucha‐Goebel, Emmanuelle Salort‐Campana, Alan Pestronk, Maggie C. Walter, Carmen Paradas, Tanya Stojkovic, Madoka Mori‐Yoshimura, Elena Bravver, Elena Pegoraro, Jerry R. Mendell, , Kate Bushby, Andrew M. Blamire, Volker Straub, Pierre G. Carlier, Jordi Diaz‐Manera
Creator:        Arbortext Advanced Print Publisher 9.1.520/W Unicode
Producer:       Acrobat Distiller 22.0 (Windows); modified using iText 4.2.0 by 1T3XT
CreationDate:   Tue Dec  6 12:06:23 2022 CET
ModDate:        Wed Nov  8 11:02:31 2023 CET
Tagged:         no
UserProperties: no
Suspects:       no
Form:           none
JavaScript:     no
Pages:          10
Encrypted:      no
Page size:      595.276 x 782.362 pts
Page rot:       0
File size:      599181 bytes
Optimized:      no
PDF version:    1.7


name                                 type              encoding         emb sub uni object ID
------------------------------------ ----------------- ---------------- --- --- --- ---------
MACMJI+CharterITCUnic                Type 1C           WinAnsi          yes yes no      41  0
MACMJJ+CharterITCUnic+fb             Type 1C           Custom           yes yes yes    302  0
MACMJK+TeXCMMathsItalic              Type 1C           WinAnsi          yes yes no      82  0
MACHAE+Calibri                       Type 1C           WinAnsi          yes yes no      42  0
MACHBF+Calibri+fb                    Type 1C           Custom           yes yes yes     43  0
MACHBG+Calibri+20                    Type 1C           WinAnsi          yes yes no      44  0
MACMHG+CalibriItalic                 Type 1C           WinAnsi          yes yes no      45  0
MACMIG+CalibriItalic+20              Type 1C           WinAnsi          yes yes no      46  0
MACMIH+CalibriBold                   Type 1C           WinAnsi          yes yes no      47  0
Times-Roman                          Type 1            WinAnsi          no  no  no       5  0
MACOBC+TeXCMMathsSymbols             Type 1C           Custom           yes yes no      80  0
MACOBD+TimesNewRoman+03              Type 1C           Custom           yes yes yes     81  0
MACOGG+Humanist777BTUnicRomanB+20    Type 1C           WinAnsi          yes yes no      93  0
MACOHH+Humanist777BTUnicRomanB+fb    Type 1C           Custom           yes yes yes     94  0
MACOFE+Humanist777BTUnicItalicB      Type 1C           WinAnsi          yes yes no      95  0
MACOGF+Humanist777BTUnicBoldB        Type 1C           WinAnsi          yes yes no      96  0
MACOED+CalibriItalic+fb              Type 1C           Custom           yes yes yes     97  0
MACOFD+Humanist777BTUnicRomanB       Type 1C           WinAnsi          yes yes no      98  0
MADGJG+CalibriBold+fb                Type 1C           Custom           yes yes yes    152  0


Jhove (Rel. 1.22.1, 2019-04-17)
 Date: 2023-11-09 02:33:31 CET
 RepresentationInformation: 284169.pdf
  ReportingModule: PDF-hul, Rel. 1.12.1 (2019-04-17)
  LastModified: 2023-11-08 11:08:52 CET
  Size: 599181
  Format: PDF
  Version: 1.7
  Status: Well-Formed, but not valid
  SignatureMatches:
   PDF-hul
  ID: PDF-HUL-122
  ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_jcsm13063-fig-0001' cannot be found
   Offset: 516218
  ID: PDF-HUL-122
  ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_jcsm13063-fig-0002' cannot be found
   Offset: 516218
  ID: PDF-HUL-122
  ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'link_jcsm13063-fig-0003' cannot be found
   Offset: 516218
  MIMEtype: application/pdf
  PDFMetadata: 
   Objects: 0
   FreeObjects: 2
   IncrementalUpdates: 0
   DocumentCatalog: 
    PageLayout: SinglePage
    PageMode: UseNone
    Outlines: 
     Item: 
      Title: Water T2 could predict functional decline in patients with dysferlinopathy
      Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@33723e30
     Item: 
      Title: Introduction
      Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@64f6106c
     Item: 
      Title: Methods
      Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@553a3d88
      Children: 
       Item: 
        Title: Patients
        Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@7a30d1e6
       Item: 
        Title: Quantitative muscle magnetic resonance imaging: acquisition and processing of Dixon and „T2H2O imaging data
        Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@5891e32e
       Item: 
        Title: Data analysis
        Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@cb0ed20
        Children: 
         Item: 
          Title: Higher or lower than median „T2H2O
          Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@8e24743
         Item: 
          Title: Identifying a „T2H2O threshold that identifies higher changes in North Star Ambulatory Assessment for Dysferlinopathy than expected
          Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@74a10858
     Item: 
      Title: Results
      Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@23fe1d71
      Children: 
       Item: 
        Title: Demographics
        Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@28ac3dc3
       Item: 
        Title: T2H2O values vary between muscles
        Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@32eebfca
       Item: 
        Title: High „T2H2O value was significantly correlated with functional deterioration
        Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@4e718207
       Item: 
        Title: Determining a „T2H2O value for prediction
        Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@1d371b2d
       Item: 
        Title: Validating „T2H2O thresholds
        Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@543c6f6d
     Item: 
      Title: Discussion
      Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@13eb8acf
     Item: 
      Title: Conflict of interest
      Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@51c8530f
     Item: 
      Title: References
      Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@7403c468
   Filters: 
    FilterPipeline: FlateDecode
    FilterPipeline: DCTDecode
   Images: 
    Image: 
     NisoImageMetadata: 
      FormatName: image/png
      ImageWidth: 228
      ImageHeight: 45
      ColorSpace: RGB
      BitsPerSample: 8
      BitsPerSampleUnit: integer
     Filter: FlateDecode
    Image: 
     NisoImageMetadata: 
      FormatName: image/jpg
      CompressionScheme: JPEG
      ImageWidth: 46
      ImageHeight: 45
      BitsPerSample: 8
      BitsPerSampleUnit: integer
     Intent: Perceptual
    Image: 
     NisoImageMetadata: 
      FormatName: image/png
      ImageWidth: 228
      ImageHeight: 45
      ColorSpace: black is zero
      BitsPerSample: 8
      BitsPerSampleUnit: integer
     Filter: FlateDecode
    Image: 
     NisoImageMetadata: 
      FormatName: image/jpg
      CompressionScheme: JPEG
      ImageWidth: 1000
      ImageHeight: 894
      ColorSpace: black is zero
      BitsPerSample: 8
      BitsPerSampleUnit: integer
    Image: 
     NisoImageMetadata: 
      FormatName: image/jpg
      CompressionScheme: JPEG
      ImageWidth: 1775
      ImageHeight: 1096
      ColorSpace: black is zero
      BitsPerSample: 8
      BitsPerSampleUnit: integer
    Image: 
     NisoImageMetadata: 
      FormatName: image/jpg
      CompressionScheme: JPEG
      ImageWidth: 2016
      ImageHeight: 872
      BitsPerSample: 8
      BitsPerSampleUnit: integer
     Intent: Perceptual
   Fonts: 
    Type1: 
     Font: 
      BaseFont: MACOGF+Humanist777BTUnicBoldB
      FontSubset: true
      FirstChar: 40
      LastChar: 117
      FontDescriptor: 
       FontName: MACOGF+Humanist777BTUnicBoldB
       Flags: Nonsymbolic
       FontBBox: -41, -229, 947, 979
       FontFile3: true
      Encoding: WinAnsiEncoding
     Font: 
      BaseFont: MACOED+CalibriItalic+fb
      FontSubset: true
      FirstChar: 1
      LastChar: 1
      FontDescriptor: 
       FontName: MACOED+CalibriItalic+fb
       Flags: Symbolic, Italic
       FontBBox: -104, -250, 812, 729
       FontFile3: true
      EncodingDictionary: 
       Differences: true
      ToUnicode: true
     Font: 
      BaseFont: MACOFD+Humanist777BTUnicRomanB
      FontSubset: true
      FirstChar: 37
      LastChar: 121
      FontDescriptor: 
       FontName: MACOFD+Humanist777BTUnicRomanB
       Flags: Nonsymbolic
       FontBBox: -218, -229, 947, 968
       FontFile3: true
      Encoding: WinAnsiEncoding
     Font: 
      BaseFont: MACMJI+CharterITCUnic
      FontSubset: true
      FirstChar: 40
      LastChar: 122
      FontDescriptor: 
       FontName: MACMJI+CharterITCUnic
       Flags: Serif, Nonsymbolic
       FontBBox: -218, -229, 937, 958
       FontFile3: true
      Encoding: WinAnsiEncoding
     Font: 
      BaseFont: MACHAE+Calibri
      FontSubset: true
      FirstChar: 37
      LastChar: 252
      FontDescriptor: 
       FontName: MACHAE+Calibri
       Flags: Serif, Nonsymbolic
       FontBBox: -93, -187, 854, 843
       FontFile3: true
      Encoding: WinAnsiEncoding
     Font: 
      BaseFont: MACHBF+Calibri+fb
      FontSubset: true
      FirstChar: 1
      LastChar: 3
      FontDescriptor: 
       FontName: MACHBF+Calibri+fb
       Flags: Symbolic
       FontBBox: -114, -302, 906, 885
       FontFile3: true
      EncodingDictionary: 
       Differences: true
      ToUnicode: true
     Font: 
      BaseFont: MACHBG+Calibri+20
      FontSubset: true
      FirstChar: 135
      LastChar: 151
      FontDescriptor: 
       FontName: MACHBG+Calibri+20
       Flags: Nonsymbolic
       FontBBox: -208, -229, 1041, 854
       FontFile3: true
      Encoding: WinAnsiEncoding
     Font: 
      BaseFont: MACMHG+CalibriItalic
      FontSubset: true
      FirstChar: 40
      LastChar: 244
      FontDescriptor: 
       FontName: MACMHG+CalibriItalic
       Flags: Serif, Nonsymbolic, Italic
       FontBBox: -104, -187, 937, 843
       FontFile3: true
      Encoding: WinAnsiEncoding
     Font: 
      BaseFont: MACMJJ+CharterITCUnic+fb
      FontSubset: true
      FirstChar: 1
      LastChar: 1
      FontDescriptor: 
       FontName: MACMJJ+CharterITCUnic+fb
       Flags: Symbolic
       FontBBox: 0, 0, 864, 739
       FontFile3: true
      EncodingDictionary: 
       Differences: true
      ToUnicode: true
     Font: 
      BaseFont: MACMIG+CalibriItalic+20
      FontSubset: true
      FirstChar: 134
      LastChar: 146
      FontDescriptor: 
       FontName: MACMIG+CalibriItalic+20
       Flags: Nonsymbolic, Italic
       FontBBox: -208, -229, 1041, 854
       FontFile3: true
      Encoding: WinAnsiEncoding
     Font: 
      BaseFont: MACMIH+CalibriBold
      FontSubset: true
      FirstChar: 48
      LastChar: 121
      FontDescriptor: 
       FontName: MACMIH+CalibriBold
       Flags: Serif, Nonsymbolic
       FontBBox: -83, -187, 875, 854
       FontFile3: true
      Encoding: WinAnsiEncoding
     Font: 
      BaseFont: MACOBC+TeXCMMathsSymbols
      FontSubset: true
      FirstChar: 1
      LastChar: 1
      FontDescriptor: 
       FontName: MACOBC+TeXCMMathsSymbols
       Flags: Symbolic
       FontBBox: -20, -958, 1114, 770
       FontFile3: true
      EncodingDictionary: 
       Differences: true
     Font: 
      BaseFont: MACOBD+TimesNewRoman+03
      FontSubset: true
      FirstChar: 1
      LastChar: 1
      FontDescriptor: 
       FontName: MACOBD+TimesNewRoman+03
       Flags: Symbolic
       FontBBox: -437, -229, 875, 885
       FontFile3: true
      EncodingDictionary: 
       Differences: true
      ToUnicode: true
     Font: 
      BaseFont: MACMJK+TeXCMMathsItalic
      FontSubset: true
      FirstChar: 60
      LastChar: 62
      FontDescriptor: 
       FontName: MACMJK+TeXCMMathsItalic
       Flags: Nonsymbolic, Italic
       FontBBox: -31, -239, 1041, 750
       FontFile3: true
      Encoding: WinAnsiEncoding
     Font: 
      BaseFont: MADGJG+CalibriBold+fb
      FontSubset: true
      FirstChar: 1
      LastChar: 1
      FontDescriptor: 
       FontName: MADGJG+CalibriBold+fb
       Flags: Symbolic
       FontBBox: -125, -302, 979, 937
       FontFile3: true
      EncodingDictionary: 
       Differences: true
      ToUnicode: true
     Font: 
      BaseFont: MACOGG+Humanist777BTUnicRomanB+20
      FontSubset: true
      FirstChar: 150
      LastChar: 150
      FontDescriptor: 
       FontName: MACOGG+Humanist777BTUnicRomanB+20
       Flags: Nonsymbolic
       FontBBox: -218, -114, 1614, 718
       FontFile3: true
      Encoding: WinAnsiEncoding
     Font: 
      BaseFont: MACOHH+Humanist777BTUnicRomanB+fb
      FontSubset: true
      FirstChar: 1
      LastChar: 1
      FontDescriptor: 
       FontName: MACOHH+Humanist777BTUnicRomanB+fb
       Flags: Symbolic
       FontBBox: 19, 0, 822, 750
       FontFile3: true
      EncodingDictionary: 
       Differences: true
      ToUnicode: true
     Font: 
      BaseFont: MACOFE+Humanist777BTUnicItalicB
      FontSubset: true
      FirstChar: 78
      LastChar: 80
      FontDescriptor: 
       FontName: MACOFE+Humanist777BTUnicItalicB
       Flags: Nonsymbolic, Italic
       FontBBox: -218, -229, 1000, 968
       FontFile3: true
      Encoding: WinAnsiEncoding
   XMP: <x:xmpmeta xmlns:x="adobe:ns:meta/">
<rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#">
<rdf:Description rdf:about="" xmlns:dc="http://purl.org/dc/elements/1.1/"><dc:format>application/pdf</dc:format><dc:identifier>doi:10.1002/jcsm.13063</dc:identifier></rdf:Description>
<rdf:Description rdf:about="" xmlns:prism="http://prismstandard.org/namespaces/basic/2.1/"><prism:doi>10.1002/jcsm.13063</prism:doi><prism:url>https://doi.org/10.1002/jcsm.13063</prism:url></rdf:Description>
<rdf:Description rdf:about="" xmlns:crossmark="http://crossref.org/crossmark/1.0/"><crossmark:MajorVersionDate>2022-09-04</crossmark:MajorVersionDate><crossmark:CrossmarkDomainExclusive>true</crossmark:CrossmarkDomainExclusive><crossmark:CrossMarkDomains><rdf:Seq><rdf:li>onlinelibrary.wiley.com</rdf:li></rdf:Seq></crossmark:CrossMarkDomains><crossmark:DOI>10.1002/jcsm.13063</crossmark:DOI></rdf:Description>
<rdf:Description rdf:about="" xmlns:pdfx="http://ns.adobe.com/pdfx/1.3/"><pdfx:CrossMarkDomains><rdf:Seq><rdf:li>onlinelibrary.wiley.com</rdf:li></rdf:Seq></pdfx:CrossMarkDomains><pdfx:CrossmarkDomainExclusive>true</pdfx:CrossmarkDomainExclusive><pdfx:doi>10.1002/jcsm.13063</pdfx:doi><pdfx:CrossmarkMajorVersionDate>2022-09-04</pdfx:CrossmarkMajorVersionDate></rdf:Description>
<rdf:Description rdf:about="" xmlns:jav="http://www.niso.org/schemas/jav/1.0/"><jav:journal_article_version>VoR</jav:journal_article_version></rdf:Description>
</rdf:RDF></x:xmpmeta>
   Pages: 
    Page: 
     Label: 2888
     Sequence: 1
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 111, 569, 114, 579
       Destination: 181
      Annotation: 
       Subtype: Link
       Rect: 251, 569, 260, 579
       Destination: 181
      Annotation: 
       Subtype: Link
       Rect: 345, 569, 354, 579
       Destination: 181
      Annotation: 
       Subtype: Link
       Rect: 470, 569, 479, 579
       Destination: 181
      Annotation: 
       Subtype: Link
       Rect: 113, 557, 117, 567
       Destination: 181
      Annotation: 
       Subtype: Link
       Rect: 165, 557, 169, 567
       Destination: 181
      Annotation: 
       Subtype: Link
       Rect: 240, 557, 244, 567
       Destination: 181
      Annotation: 
       Subtype: Link
       Rect: 308, 557, 312, 567
       Destination: 181
      Annotation: 
       Subtype: Link
       Rect: 377, 557, 381, 567
       Destination: 181
      Annotation: 
       Subtype: Link
       Rect: 438, 557, 442, 567
       Destination: 181
      Annotation: 
       Subtype: Link
       Rect: 501, 557, 505, 567
       Destination: 181
      Annotation: 
       Subtype: Link
       Rect: 160, 545, 177, 555
       Destination: 181
      Annotation: 
       Subtype: Link
       Rect: 299, 545, 306, 555
       Destination: 181
      Annotation: 
       Subtype: Link
       Rect: 367, 545, 375, 555
       Destination: 181
      Annotation: 
       Subtype: Link
       Rect: 450, 545, 458, 555
       Destination: 181
      Annotation: 
       Subtype: Link
       Rect: 529, 545, 536, 555
       Destination: 181
      Annotation: 
       Subtype: Link
       Rect: 117, 533, 125, 543
       Destination: 181
      Annotation: 
       Subtype: Link
       Rect: 231, 533, 238, 543
       Destination: 181
      Annotation: 
       Subtype: Link
       Rect: 300, 533, 307, 543
       Destination: 181
      Annotation: 
       Subtype: Link
       Rect: 378, 533, 385, 543
       Destination: 181
      Annotation: 
       Subtype: Link
       Rect: 457, 533, 465, 543
       Destination: 181
      Annotation: 
       Subtype: Link
       Rect: 213, 521, 217, 531
       Destination: 181
      Annotation: 
       Subtype: Link
       Rect: 302, 521, 305, 531
       Destination: 181
      Annotation: 
       Subtype: Link
       Rect: 366, 521, 369, 531
       Destination: 181
      Annotation: 
       Subtype: Link
       Rect: 440, 521, 447, 531
       Destination: 181
      Annotation: 
       Subtype: Link
       Rect: 128, 509, 151, 519
       Destination: 181
      Annotation: 
       Subtype: Link
       Rect: 158, 506, 168, 516
      Annotation: 
       Subtype: Link
       Rect: 204, 33, 290, 40
      Annotation: 
       Subtype: Link
       Rect: 519, 782, 595, 767
     Thumb: true
    Page: 
     Label: 2889
     Sequence: 2
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 253, 621, 354, 628
      Annotation: 
       Subtype: Link
       Rect: 167, 503, 171, 512
       Destination: 149
      Annotation: 
       Subtype: Link
       Rect: 129, 455, 138, 464
       Destination: 149
      Annotation: 
       Subtype: Link
       Rect: 123, 431, 127, 440
       Destination: 149
      Annotation: 
       Subtype: Link
       Rect: 254, 383, 263, 392
       Destination: 149
      Annotation: 
       Subtype: Link
       Rect: 157, 347, 166, 356
       Destination: 149
      Annotation: 
       Subtype: Link
       Rect: 184, 263, 197, 272
       Destination: 149
      Annotation: 
       Subtype: Link
       Rect: 143, 227, 159, 236
       Destination: 149
      Annotation: 
       Subtype: Link
       Rect: 132, 203, 155, 212
       Destination: 149
      Annotation: 
       Subtype: Link
       Rect: 180, 131, 187, 140
       Destination: 163
      Annotation: 
       Subtype: Link
       Rect: 152, 71, 159, 80
       Destination: 163
      Annotation: 
       Subtype: Link
       Rect: 352, 503, 370, 512
       Destination: 163
      Annotation: 
       Subtype: Link
       Rect: 362, 383, 378, 392
       Destination: 163
      Annotation: 
       Subtype: Link
       Rect: 397, 323, 413, 332
       Destination: 163
      Annotation: 
       Subtype: Link
       Rect: 337, 275, 354, 284
       Destination: 163
      Annotation: 
       Subtype: Link
       Rect: 492, 227, 499, 236
       Destination: 163
     Thumb: true
    Page: 
     Label: 2890
     Sequence: 3
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 116, 543, 123, 552
       Destination: 163
      Annotation: 
       Subtype: Link
       Rect: 261, 399, 278, 408
       Destination: 149
      Annotation: 
       Subtype: Link
       Rect: 392, 618, 396, 627
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 365, 435, 372, 444
       Destination: 163
      Annotation: 
       Subtype: Link
       Rect: 357, 351, 364, 360
       Destination: 163
      Annotation: 
       Subtype: Link
       Rect: 436, 327, 452, 336
       Destination: 163
     Thumb: true
    Page: 
     Label: 2891
     Sequence: 4
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 57, 690, 152, 699
      Annotation: 
       Subtype: Link
       Rect: 263, 670, 271, 679
       Destination: 163
      Annotation: 
       Subtype: Link
       Rect: 200, 413, 205, 423
       Destination: 90
      Annotation: 
       Subtype: Link
       Rect: 374, 476, 377, 486
       Destination: 149
      Annotation: 
       Subtype: Link
       Rect: 404, 400, 504, 410
      Annotation: 
       Subtype: Link
       Rect: 419, 101, 424, 111
       Destination: 90
     Thumb: true
    Page: 
     Label: 2892
     Sequence: 5
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 258, 197, 263, 207
       Destination: 90
      Annotation: 
       Subtype: Link
       Rect: 232, 114, 236, 123
       Destination: 90
      Annotation: 
       Subtype: Link
       Rect: 368, 247, 373, 257
       Destination: 90
      Annotation: 
       Subtype: Link
       Rect: 404, 65, 408, 75
       Destination: null
     Thumb: true
    Page: 
     Label: 2893
     Sequence: 6
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 54, 89, 59, 99
       Destination: 112
      Annotation: 
       Subtype: Link
       Rect: 104, 89, 109, 99
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 186, 89, 190, 99
       Destination: 112
      Annotation: 
       Subtype: Link
       Rect: 329, 142, 334, 151
       Destination: 112
     Thumb: true
    Page: 
     Label: 2894
     Sequence: 7
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 205, 598, 221, 607
       Destination: 163
      Annotation: 
       Subtype: Link
       Rect: 179, 550, 186, 559
       Destination: 163
      Annotation: 
       Subtype: Link
       Rect: 126, 526, 133, 535
       Destination: 163
      Annotation: 
       Subtype: Link
       Rect: 82, 214, 89, 223
       Destination: 163
      Annotation: 
       Subtype: Link
       Rect: 183, 70, 190, 79
       Destination: 163
      Annotation: 
       Subtype: Link
       Rect: 368, 574, 375, 583
       Destination: 163
      Annotation: 
       Subtype: Link
       Rect: 447, 514, 454, 523
       Destination: 163
      Annotation: 
       Subtype: Link
       Rect: 387, 454, 394, 463
       Destination: 149
      Annotation: 
       Subtype: Link
       Rect: 513, 430, 520, 439
       Destination: 163
      Annotation: 
       Subtype: Link
       Rect: 511, 382, 518, 391
       Destination: 149
      Annotation: 
       Subtype: Link
       Rect: 499, 322, 506, 331
       Destination: 163
      Annotation: 
       Subtype: Link
       Rect: 467, 286, 474, 295
       Destination: 163
      Annotation: 
       Subtype: Link
       Rect: 409, 250, 417, 259
       Destination: 163
      Annotation: 
       Subtype: Link
       Rect: 398, 118, 405, 127
       Destination: 163
     Thumb: true
    Page: 
     Label: 2895
     Sequence: 8
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 147, 682, 163, 691
       Destination: 149
      Annotation: 
       Subtype: Link
       Rect: 197, 382, 213, 391
       Destination: 163
      Annotation: 
       Subtype: Link
       Rect: 422, 706, 430, 715
       Destination: 163
      Annotation: 
       Subtype: Link
       Rect: 431, 622, 438, 631
       Destination: 163
      Annotation: 
       Subtype: Link
       Rect: 386, 418, 394, 427
       Destination: 163
     Thumb: true
    Page: 
     Label: 2896
     Sequence: 9
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 189, 694, 207, 703
       Destination: 163
      Annotation: 
       Subtype: Link
       Rect: 84, 646, 100, 655
       Destination: 163
      Annotation: 
       Subtype: Link
       Rect: 470, 701, 538, 711
      Annotation: 
       Subtype: Link
       Rect: 302, 690, 333, 699
      Annotation: 
       Subtype: Link
       Rect: 325, 641, 439, 651
     Thumb: true
    Page: 
     Label: 2897
     Sequence: 10
     Thumb: true
  Checksum: 2c830a34
   Type: CRC32
  Checksum: 60ffdd11ba1bde0f9aec121406b7591b
   Type: MD5
  Checksum: 8d08d6892a7c8d32e4e0a23e1f4816e32315eae7
   Type: SHA-1