85a6f02c75ee4ee8de80e3f70445df90 284471.pdf 3dcb4af477ee24b67c30cd0596355a8e637c3a23 284471.pdf bd30a324121af369f9a2a0421cbfb10606bd8f328eb8d8bde96f288ad80735c0 284471.pdf Title: Impact of the COVID-19 Pandemic on Maternal Well-Being during Pregnancy Subject: The outbreak of a pandemic has negative psychological effects. We aimed to determine the impact of the SARS-CoV-2 pandemic during pregnancy and identify the risk factors for maternal well-being. A multicenter, prospective, population-based study was carried out that included women (n = 1320) who were pregnant during the SARS-CoV-2 pandemic in Barcelona (Spain) compared against a pre-pandemic cohort (n = 345). Maternal well-being was assessed using the validated World Health Organization Well-Being Index Questionnaire (WHO-5 Index). Pregnant women attended during the COVID-19 pandemic showed worst WHO-5 well-being scores (median (IQR) of 56 (36–72) for the pandemic cohort vs. 64 (52–76) for the pre-pandemic cohort p < 0.001), with 42.8% of women presenting a poor well-being score vs. 28% for the pre-pandemic cohort (p < 0.001). Presence of a previous psychiatric disorder (OR 7.1; 95% CI 2.6–19, p < 0.001), being in the third trimester of pregnancy (OR 1.7; 95% CI 1.5–2, p < 0.001), or requiring hospital admission for COVID-19 (OR 4.7; 95% CI 1.4–16.7, p = 0.014), significantly contributed to low maternal well-being during the COVID-19 pandemic (multivariate analysis). Being infected by SARS-CoV-2 was not associated with a lower well-being score. We conclude that, during the COVID-19 pandemic, there were higher rates of poor maternal well-being; the infection of SARS-CoV-2 itself did not worsen maternal well-being, but other factors as psychiatric disorders, being in the third trimester of pregnancy or hospital admission for COVID-19 disease did. Keywords: COVID-19; SARS-CoV-2; pandemic; well-being; pregnancy; psychiatric disorders;anxiety; depression Author: Rosalia Pascal, Francesca Crovetto, Irene Casas, Lina Youssef, Cristina Trilla, Marta Larroya, Alex Cahuana, David Boada, Maria Foraster, Elisa Llurba, Jordi Sunyer, Fàtima Crispi, Eduard Gratacos and María Dolores Gómez-Roig Creator: LaTeX with hyperref Producer: pdfTeX-1.40.21 CreationDate: Fri Apr 15 11:39:23 2022 CEST ModDate: Fri Apr 15 11:51:44 2022 CEST Tagged: no UserProperties: no Suspects: no Form: none JavaScript: no Pages: 15 Encrypted: no Page size: 595.276 x 841.89 pts (A4) Page rot: 0 File size: 1800972 bytes Optimized: no PDF version: 1.7 name type encoding emb sub uni object ID ------------------------------------ ----------------- ---------------- --- --- --- --------- RSYDPD+VnURWPalladioL-Bold Type 1 Custom yes yes no 10 0 UKXHGC+VnURWPalladioL Type 1 Custom yes yes no 15 0 TCETEQ+URWPalladioL-Bold Type 1 Custom yes yes no 19 0 ZPKTPG+URWPalladioL-Roma Type 1 Custom yes yes no 24 0 VHLNDW+URWPalladioL-Ital Type 1 Custom yes yes no 28 0 MCBCCI+SourceSansRoman-Regular Type 1C Custom yes yes no 36 0 MCBCCM+SourceSansRoman.613wght Type 1C Custom yes yes no 40 0 MCBCCO+SourceSansRoman-Bold Type 1C Custom yes yes no 44 0 XPUSBJ+TimesNewRomanPS-BoldItalicMT Type 1C WinAnsi yes yes no 56 0 BSDWLC+TimesNewRomanPSMT Type 1C WinAnsi yes yes no 59 0 RWBCRL+CMSY10 Type 1 Builtin yes yes no 81 0 QLBIEB+URWPalladioL-BoldItal Type 1 Custom yes yes no 88 0 RFECCF+EURM10 Type 1 Builtin yes yes no 92 0 CIDFont+F3 CID TrueType Identity-H yes no yes 104 0 CIDFont+F1 CID TrueType Identity-H yes no yes 112 0 CIDFont+F2 CID TrueType Identity-H yes no yes 120 0 CIDFont+F5 CID TrueType Identity-H yes no yes 128 0 CIDFont+F3 CID TrueType Identity-H yes no yes 142 0 CIDFont+F1 CID TrueType Identity-H yes no yes 150 0 CIDFont+F2 CID TrueType Identity-H yes no yes 158 0 CIDFont+F4 CID TrueType Identity-H yes no yes 166 0 CIDFont+F3 CID TrueType Identity-H yes no yes 181 0 CIDFont+F1 CID TrueType Identity-H yes no yes 189 0 CIDFont+F2 CID TrueType Identity-H yes no yes 197 0 CIDFont+F4 CID TrueType Identity-H yes no yes 205 0 CIDFont+F3 CID TrueType Identity-H yes no yes 239 0 CIDFont+F1 CID TrueType Identity-H yes no yes 247 0 CIDFont+F2 CID TrueType Identity-H yes no yes 255 0 CIDFont+F4 CID TrueType Identity-H yes no yes 263 0 Jhove (Rel. 1.28.0, 2023-05-18) Date: 2024-02-24 02:31:19 CET RepresentationInformation: 284471.pdf ReportingModule: PDF-hul, Rel. 1.12.4 (2023-03-16) LastModified: 2024-02-23 10:43:07 CET Size: 1800972 Format: PDF Version: 1.7 Status: Well-Formed and valid SignatureMatches: PDF-hul MIMEtype: application/pdf PDFMetadata: Objects: 425 FreeObjects: 1 IncrementalUpdates: 0 DocumentCatalog: PageLayout: SinglePage PageMode: UseNone Outlines: Item: Title: Introduction Destination: section.1 Item: Title: Materials and Methods Destination: section.2 Children: Item: Title: Study Design and Participants Destination: subsection.2.1 Item: Title: Aims of the Study Destination: subsection.2.2 Item: Title: Data Collection Destination: subsection.2.3 Item: Title: Statistical Analysis Destination: subsection.2.4 Item: Title: Results Destination: section.3 Children: Item: Title: Characteristics of the Study Population Destination: subsection.3.1 Item: Title: Maternal Well-Being Destination: subsection.3.2 Item: Title: Lockdown Characteristics Destination: subsection.3.3 Item: Title: Discussion Destination: section.4 Children: Item: Title: Main Findings Destination: subsection.4.1 Item: Title: Clinical Relevance Destination: subsection.4.2 Item: Title: Strengths and Limitations Destination: subsection.4.3 Item: Title: Conclusions Destination: section.5 Item: Title: Appendix A Destination: section.A. Children: Item: Title: COVID-19 Evaluation Destination: subsection.A.1 Item: Title: Sample Collection Destination: subsection.A.2 Item: Title: Appendix B Destination: section.B. Item: Title: References Destination: figure.caption.17 Info: Title: Impact of the COVID-19 Pandemic on Maternal Well-Being during Pregnancy Author: Rosalia Pascal, Francesca Crovetto, Irene Casas, Lina Youssef, Cristina Trilla, Marta Larroya, Alex Cahuana, David Boada, Maria Foraster, Elisa Llurba, Jordi Sunyer, Fàtima Crispi, Eduard Gratacos and María Dolores Gómez-Roig Subject: The outbreak of a pandemic has negative psychological effects. We aimed to determine the impact of the SARS-CoV-2 pandemic during pregnancy and identify the risk factors for maternal well-being. A multicenter, prospective, population-based study was carried out that included women (n = 1320) who were pregnant during the SARS-CoV-2 pandemic in Barcelona (Spain) compared against a pre-pandemic cohort (n = 345). Maternal well-being was assessed using the validated World Health Organization Well-Being Index Questionnaire (WHO-5 Index). Pregnant women attended during the COVID-19 pandemic showed worst WHO-5 well-being scores (median (IQR) of 56 (36 72) for the pandemic cohort vs. 64 (52 76) for the pre-pandemic cohort p < 0.001), with 42.8% of women presenting a poor well-being score vs. 28% for the pre-pandemic cohort (p < 0.001). Presence of a previous psychiatric disorder (OR 7.1; 95% CI 2.6 19, p < 0.001), being in the third trimester of pregnancy (OR 1.7; 95% CI 1.5 2, p < 0.001), or requiring hospital admission for COVID-19 (OR 4.7; 95% CI 1.4 16.7, p = 0.014), significantly contributed to low maternal well-being during the COVID-19 pandemic (multivariate analysis). Being infected by SARS-CoV-2 was not associated with a lower well-being score. We conclude that, during the COVID-19 pandemic, there were higher rates of poor maternal well-being; the infection of SARS-CoV-2 itself did not worsen maternal well-being, but other factors as psychiatric disorders, being in the third trimester of pregnancy or hospital admission for COVID-19 disease did. 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