3be9ed5c76dfc7d72749eec07a2f20bd 286333.pdf 903d3d50056115044e3bf61cfae0bc3426dd1235 286333.pdf f11a8fd920a48ad453c6239d3c51dbb661afcb430e0538f802e9e6988e42fb96 286333.pdf Title: Lifetime Dual Disorder Screening and Treatment Retention: A Pilot Cohort Study Subject: The coexistence of a substance use disorder and another mental disorder in the same individual has been called dual disorder or dual diagnosis. This study aimed to examine the prevalence of lifetime dual disorder in individuals with alcohol or cocaine use disorder and their retention in treatment. We conducted a pilot cohort study of individuals (n = 1356) with alcohol or cocaine use disorder admitted to treatment in the public outpatient services of Barcelona (Spain) from January 2015 to August 2017 (followed-up until February 2018). Descriptive statistics, Kaplan–Meier survival curves and a multivariable Cox regression model were estimated. The lifetime prevalence of screening positive for dual disorder was 74%. At 1 year of follow-up, >75% of the cohort remained in treatment. On multivariable analysis, the factors associated with treatment dropout were a positive screening for lifetime dual disorder (HR = 1.26; 95% CI = 1.00–1.60), alcohol use (HR = 1.35; 95% CI = 1.04–1.77), polysubstance use (alcohol or cocaine and cannabis use) (HR = 1.60; 95% CI = 1.03–2.49) and living alone (HR = 1.34; 95% CI = 1.04–1.72). Lifetime dual disorder is a prevalent issue among individuals with alcohol or cocaine use disorders and could influence their dropout from treatment in public outpatient drug dependence care centres, along with alcohol use, polysubstance use and social conditions, such as living alone. We need a large-scale study with prolonged follow-up to confirm these preliminary results. Keywords: dual disorder; mental disorders; screening; cocaine use disorder; alcohol use disorder; substance-related disorders; treatment retention Author: Beatriz Puértolas-Gracia, María Gabriela Barbaglia, Mercè Gotsens, Oleguer Parés-Badell, María Teresa Brugal, Marta Torrens, Lara Treviño, Concepción Rodríguez-Díaz, José María Vázquez-Vázquez, Alicia Pascual, Marcela Coromina-Gimferrer, Míriam Jiménez-Dueñas, Israel Oliva, Erick González, Nicanor Mestre and Montse Bartroli Creator: LaTeX with hyperref Producer: pdfTeX-1.40.21 CreationDate: Fri Jul 1 04:02:07 2022 CEST ModDate: Fri Jul 1 04:05:50 2022 CEST Custom Metadata: no Metadata Stream: no Tagged: no UserProperties: no Suspects: no Form: none JavaScript: no Pages: 17 Encrypted: no Page size: 595.276 x 841.89 pts (A4) Page rot: 0 File size: 488998 bytes Optimized: no PDF version: 1.7 name type encoding emb sub uni object ID ------------------------------------ ----------------- ---------------- --- --- --- --------- UTQWUX+TeX-tipa8 Type 1 Builtin yes yes no 10 0 CJNZPN+URWPalladioL-Bold Type 1 Custom yes yes no 14 0 NTPMRJ+URWPalladioL-Roma Type 1 Custom yes yes no 19 0 IBVRXZ+URWPalladioL-Ital Type 1 Custom yes yes no 23 0 DSBBYX+VnURWPalladioL Type 1 Custom yes yes no 27 0 XYDCIJ+VnURWPalladioL-Bold Type 1 Custom yes yes no 32 0 XPUSBJ+TimesNewRomanPS-BoldItalicMT Type 1C WinAnsi yes yes no 50 0 BSDWLC+TimesNewRomanPSMT Type 1C WinAnsi yes yes no 53 0 KWKPAT+CMSY10 Type 1 Builtin yes yes no 75 0 JBDGLK+URWPalladioL-BoldItal Type 1 Custom yes yes no 88 0 IYLPED+CMBSY10 Type 1 Builtin yes yes no 92 0 INKOJD+Arial CID TrueType Identity-H yes yes yes 109 0 INKKNP+PalatinoLinotype,Bold TrueType WinAnsi yes yes no 115 0 INKKOB+PalatinoLinotype TrueType WinAnsi yes yes no 118 0 INKKPD+PalatinoLinotype,Italic TrueType WinAnsi yes yes no 121 0 CRUZTT+VnURWPalladioL-Italic Type 1 Custom yes yes no 155 0 Jhove (Rel. 1.28.0, 2023-05-18) Date: 2024-03-21 02:37:00 CET RepresentationInformation: 286333.pdf ReportingModule: PDF-hul, Rel. 1.12.4 (2023-03-16) LastModified: 2024-03-20 12:02:23 CET Size: 488998 Format: PDF Version: 1.7 Status: Well-Formed and valid SignatureMatches: PDF-hul MIMEtype: application/pdf PDFMetadata: Objects: 318 FreeObjects: 1 IncrementalUpdates: 0 DocumentCatalog: PageLayout: SinglePage PageMode: UseNone Outlines: Item: Title: Introduction Destination: section.1 Item: Title: Materials and Methods Destination: section.2 Children: Item: Title: Design and Study Population Destination: subsection.2.1 Item: Title: Information Sources Destination: subsection.2.2 Item: Title: Variables Destination: subsection.2.3 Item: Title: Statistical Analysis Destination: subsection.2.4 Item: Title: Results Destination: section.3 Children: Item: Title: Sociodemographic and Clinical Characteristics Destination: subsection.3.1 Item: Title: Characteristics of Treatment Retention Destination: subsection.3.2 Item: Title: Multivariable Explanatory Models of Treatment Dropout Destination: subsection.3.3 Item: Title: Discussion Destination: section.4 Item: Title: Conclusions Destination: section.5 Item: Title: Appendix A Destination: section.A. Item: Title: References Destination: table.caption.9 Info: Title: Lifetime Dual Disorder Screening and Treatment Retention: A Pilot Cohort Study Author: Beatriz Puértolas-Gracia, María Gabriela Barbaglia, Mercè Gotsens, Oleguer Parés-Badell, María Teresa Brugal, Marta Torrens, Lara Treviño, Concepción Rodríguez-Díaz, José María Vázquez-Vázquez, Alicia Pascual, Marcela Coromina-Gimferrer, Míriam Jiménez-Dueñas, Israel Oliva, Erick González, Nicanor Mestre and Montse Bartroli Subject: The coexistence of a substance use disorder and another mental disorder in the same individual has been called dual disorder or dual diagnosis. This study aimed to examine the prevalence of lifetime dual disorder in individuals with alcohol or cocaine use disorder and their retention in treatment. We conducted a pilot cohort study of individuals (n = 1356) with alcohol or cocaine use disorder admitted to treatment in the public outpatient services of Barcelona (Spain) from January 2015 to August 2017 (followed-up until February 2018). Descriptive statistics, Kaplan Meier survival curves and a multivariable Cox regression model were estimated. The lifetime prevalence of screening positive for dual disorder was 74%. At 1 year of follow-up, >75% of the cohort remained in treatment. On multivariable analysis, the factors associated with treatment dropout were a positive screening for lifetime dual disorder (HR = 1.26; 95% CI = 1.00 1.60), alcohol use (HR = 1.35; 95% CI = 1.04 1.77), polysubstance use (alcohol or cocaine and cannabis use) (HR = 1.60; 95% CI = 1.03 2.49) and living alone (HR = 1.34; 95% CI = 1.04 1.72). Lifetime dual disorder is a prevalent issue among individuals with alcohol or cocaine use disorders and could influence their dropout from treatment in public outpatient drug dependence care centres, along with alcohol use, polysubstance use and social conditions, such as living alone. We need a large-scale study with prolonged follow-up to confirm these preliminary results. 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