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Title:          Towards a druggable epitranscriptome: Compounds that target RNA modifications in cancer
Subject:        British J Pharmacology 2022.179:2868-2889
Keywords:       10.1111/bph.15604 and A‐to‐I‐editing; cancer; epitranscriptomics; pseudouridine; RNA methylation; small‐molecule inhibitors; therapy
Author:         María Berdasco and Manel Esteller
Creator:        Arbortext Advanced Print Publisher 9.1.520/W Unicode
Producer:       Acrobat Distiller 22.0 (Windows); modified using iText 4.2.0 by 1T3XT
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     Item: 
      Title: Towards a druggable epitranscriptome: Compounds that target RNA modifications in cancer
      Destination: atl_BPH_15604_
      Children: 
       Item: 
        Title: 1  INTRODUCTION
        Destination: HeadingBPH_15604bph15604-sec-0001
       Item: 
        Title: 2  THE EPITRANSCRIPTOME VERSUS THE EPIGENOME
        Destination: HeadingBPH_15604bph15604-sec-0002
       Item: 
        Title: 3  NON-CANONICAL CODING RNA MODIFICATIONS: DISTRIBUTION, DYNAMICS AND FUNCTION
        Destination: HeadingBPH_15604bph15604-sec-0003
        Children: 
         Item: 
          Title: 3.1  N6-methyladenosine
          Destination: HeadingBPH_15604bph15604-sec-0004
         Item: 
          Title: 3.2  N1-methyladenosine
          Destination: HeadingBPH_15604bph15604-sec-0005
         Item: 
          Title: 3.3  5-methylcytosine
          Destination: HeadingBPH_15604bph15604-sec-0006
         Item: 
          Title: 3.4  Pseudouridine
          Destination: HeadingBPH_15604bph15604-sec-0007
         Item: 
          Title: 3.5  Adenosine-to-inosine editing
          Destination: HeadingBPH_15604bph15604-sec-0008
       Item: 
        Title: 4  DE-REGULATED EPITRANSCRIPTOME IN CANCER
        Destination: HeadingBPH_15604bph15604-sec-0009
        Children: 
         Item: 
          Title: 4.1  Alterations of N6-methyladenosine contents in cancer
          Destination: HeadingBPH_15604bph15604-sec-0010
         Item: 
          Title: 4.2  Alterations of N1-methyladenosine contents in cancer
          Destination: HeadingBPH_15604bph15604-sec-0011
         Item: 
          Title: 4.3  Alteration of 5-methylcytosine content in cancer
          Destination: HeadingBPH_15604bph15604-sec-0012
         Item: 
          Title: 4.4  Pseudouridine alterations associated with cancer
          Destination: HeadingBPH_15604bph15604-sec-0013
         Item: 
          Title: 4.5  Adenosine-to-inosine editing in cancer
          Destination: HeadingBPH_15604bph15604-sec-0014
       Item: 
        Title: 5  PHARMACOLOGICAL STRATEGIES AIM TO TARGET THE EPITRANSCRIPTOME
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         Item: 
          Title: 5.1  RNA methyltransferase inhibitors
          Destination: HeadingBPH_15604bph15604-sec-0016
         Item: 
          Title: 5.2  Inhibitors of RNA demethylases
          Destination: HeadingBPH_15604bph15604-sec-0017
         Item: 
          Title: 5.3  Targeting other RNA modifications
          Destination: HeadingBPH_15604bph15604-sec-0018
       Item: 
        Title: 6  CONCLUSION
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        Children: 
         Item: 
          Title: 6.1  Nomenclature of targets and ligands
          Destination: HeadingBPH_15604bph15604-sec-0020
       Item: 
        Title: ACKNOWLEDGEMENTS
        Destination: HeadingBPH_15604bph15604-sec-0021
       Item: 
        Title: CONFLICT OF INTERESTS
        Destination: HeadingBPH_15604bph15604-sec-0022
       Item: 
        Title: REFERENCES
        Destination: HeadingBPH_15604bph15604-bibl-00011
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