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PrintArea: CropBox PageClip: CropBox PageLayout: SinglePage PageMode: UseOutlines Outlines: Item: Title: Efficacy and Safety of Ruxolitinib in Steroid-Refractory/Dependent Chronic Graft-versus-Host Disease: Real-World Data and Challenges Destination: Head1 Children: Item: Title: INTRODUCTION Destination: Head2 Item: Title: METHODS Destination: Head3 Children: Item: Title: Patients Destination: Head4 Item: Title: Ruxolitinib Dosing and Response Destination: Head5 Item: Title: Supportive Care and Anti-Infectious Prophylaxis Destination: Head6 Item: Title: Statistical Methods Destination: Head7 Item: Title: RESULTS Destination: Head8 Children: Item: Title: Study Population Destination: Head9 Item: Title: Response to Ruxolitinib Destination: Head10 Item: Title: Toxicity Destination: Head11 Item: Title: Long-Term Outcomes Destination: Head12 Item: Title: DISCUSSION Destination: Head13 Item: Title: ACKNOWLEDGMENTS Destination: Head14 Item: Title: Conflict of interest statement Destination: Head15 Item: Title: Authorship statement Destination: Head16 Item: Title: REFERENCES Destination: Head17 Info: Producer: Acrobat Distiller 9.0.0 (Windows) CreationDate: Fri Aug 24 13:03:10 CEST 2012 ModDate: Wed Feb 20 12:20:50 CET 2013 ID: 0x3adf785be59bc0c58a1ec7f61f9e47e3, 0x9fa1cad6d0f57c9af0569346fb7c35dd Filters: FilterPipeline: FlateDecode FilterPipeline: DCTDecode Images: Image: NisoImageMetadata: FormatName: image/jpg CompressionScheme: JPEG ImageWidth: 575 ImageHeight: 194 ColorSpace: RGB BitsPerSample: 8 BitsPerSampleUnit: integer Image: NisoImageMetadata: FormatName: image/jpg CompressionScheme: JPEG ImageWidth: 1250 ImageHeight: 845 ColorSpace: RGB BitsPerSample: 8 BitsPerSampleUnit: integer Fonts: Type1: Font: BaseFont: DNNKOE+AdvP4C9542 FontSubset: true FirstChar: 60 LastChar: 62 FontDescriptor: FontName: DNNKOE+AdvP4C9542 Flags: Nonsymbolic FontBBox: 0, -208, 979, 677 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: DNOEMI+AdvOTf2586c63+fb FontSubset: true 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Differences: true Font: BaseFont: DNNIFA+AdvTTb83ee1dd.B FontSubset: true FirstChar: 37 LastChar: 121 FontDescriptor: FontName: DNNIFA+AdvTTb83ee1dd.B Flags: Nonsymbolic FontBBox: -93, -250, 1041, 989 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: DNNIDN+AdvP4C4E59 FontSubset: true FirstChar: 2 LastChar: 126 FontDescriptor: FontName: DNNIDN+AdvP4C4E59 Flags: Symbolic FontBBox: -31, -250, 1000, 750 FontFile3: true EncodingDictionary: Differences: true ToUnicode: true XMP: 2012-08-24T16:03:10+05:30 Elsevier 2013-02-20T16:20:50+05:30 2013-02-20T16:20:50+05:30 Acrobat Distiller 9.0.0 (Windows) "Steroid-refractory-chronic GvHD"; "Ruxolitinib"; "Steroids"; "GVHD-flare"; "Toxicity-profile" application/pdf doi:10.1016/j.jtct.2021.10.015 Efficacy and Safety of Ruxolitinib in Steroid-Refractory/Dependent Chronic Graft-versus-Host Disease: Real-World Data and Challenges Sara Redondo Albert Esquirol Silvana Novelli Ana Carolina Caballero Ana Garrido Guadalupe Oñate Jordi López Carol Moreno Silvanna-Daniela Saavedra Miquel Granell Javier Briones Jorge Sierra Rodrigo Martino Irene García-Cadenas Transplantation and Cellular Therapy, 28 (2022) 43.e1-43.e5. doi:10.1016/j.jtct.2021.10.015 Elsevier Inc. Steroid-refractory-chronic GvHD Ruxolitinib Steroids GVHD-flare Toxicity-profile uuid:fd8cfc10-4791-4a8b-8025-00abb91efa0c uuid:d56e5e26-6274-4fa7-ad08-30fc2ecddb91 journal © 2021 The American Society for Transplantation and Cellular Therapy. Published by Elsevier Inc. All rights reserved. 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