81b8425185e326685722f3bd5c12cc6f 290540.pdf 5eaee0bed50aa46daf1f7b312f85f810cc6c5d50 290540.pdf 860aa39d3acfa17bc383cd448c61674af68a191daedbffbdbac5fbe08f169f04 290540.pdf Title: Domain generalization in deep learning for contrast-enhanced imaging Subject: Computers in Biology and Medicine, 149 (2022) 106052. doi:10.1016/j.compbiomed.2022.106052 Keywords: Deep learning,Contrast-enhanced imaging,Domain generalization,Cardiac image segmentation,Data augmentation,Transfer learning Author: Carla Sendra-Balcells Creator: Elsevier Producer: Acrobat Distiller 8.1.0 (Windows) CreationDate: Mon Sep 12 14:04:29 2022 CEST ModDate: Sat Sep 17 18:12:52 2022 CEST Custom Metadata: yes Metadata Stream: yes Tagged: no UserProperties: no Suspects: no Form: none JavaScript: no Pages: 12 Encrypted: no Page size: 595.276 x 793.701 pts Page rot: 0 File size: 4148161 bytes Optimized: yes PDF version: 1.7 name type encoding emb sub uni object ID ------------------------------------ ----------------- ---------------- --- --- --- --------- EEFKWM+STIXMath-Regular Type 1 Builtin yes yes yes 789 0 LMYLQZ+CharisSIL-Bold Type 1 Builtin yes yes yes 793 0 AGQOEG+t1-uni-regular Type 1 Builtin yes yes yes 797 0 EOSLZE+CharisSIL Type 1 Builtin yes yes yes 801 0 EWWIMW+CharisSIL-Italic Type 1 Builtin yes yes yes 805 0 MXHSJR+CharisSIL CID TrueType Identity-H yes yes yes 780 0 SMFCCU+CharisSIL-Italic CID TrueType Identity-H yes yes yes 443 0 OUILJB+u-charis-symbol Type 1 Builtin yes yes yes 452 0 ABDNXX+STIXMath-Italic Type 1 Builtin yes yes yes 456 0 TKLJNA+STIXMathScript-Regular Type 1 Builtin yes yes yes 119 0 Jhove (Rel. 1.28.0, 2023-05-18) Date: 2024-04-11 02:39:36 CEST RepresentationInformation: 290540.pdf ReportingModule: PDF-hul, Rel. 1.12.4 (2023-03-16) LastModified: 2024-04-10 13:19:30 CEST Size: 4148161 Format: PDF Version: 1.7 Status: Well-Formed and valid SignatureMatches: PDF-hul MIMEtype: application/pdf Profile: Linearized PDF PDFMetadata: Objects: 969 FreeObjects: 1 IncrementalUpdates: 1 DocumentCatalog: PageLayout: SinglePage PageMode: UseOutlines Language: en-US Outlines: Item: Title: Domain generalization in deep learning for contrast-enhanced imaging Children: Item: Title: Introduction Children: Item: Title: Problem and motivation Item: Title: Goals and contributions Item: Title: Methods Children: Item: Title: Datasets Children: Item: Title: EMIDEC dataset: University Hospital Dijon, France Item: Title: MSCMR dataset: Shanghai Renji Hospital, China Item: Title: VH dataset: Vall d'Hebron Hospital, Spain Item: Title: STPAU dataset: Sant Pau Hospital, Spain Item: Title: Single-center model with data augmentation Item: Title: Image harmonization at testing Item: Title: Transfer learning from the original to the new clinical site Item: Title: Multi-center model Item: Title: Baseline workflow Children: Item: Title: Pre-processing Item: Title: Post-processing Item: Title: Network architecture Item: Title: Implementation details Item: Title: Performance evaluation Item: Title: Results Children: Item: Title: Experiment 1: Effect of data augmentation Item: Title: Experiment 2: Effect of image harmonization Item: Title: Experiment 3: Effect of transfer learning Item: Title: Experiment 4: Comparison to a multi-center scenario Item: Title: Qualitative analysis Item: Title: Discussion Item: Title: Conclusions Item: Title: CRediT authorship contribution statement Item: Title: Declaration of competing interest Item: Title: Data availability Item: Title: References Info: Title: Domain generalization in deep learning for contrast-enhanced imaging Author: Carla Sendra-Balcells Subject: Computers in Biology and Medicine, 149 (2022) 106052. doi:10.1016/j.compbiomed.2022.106052 Keywords: Deep learning,Contrast-enhanced imaging,Domain generalization,Cardiac image segmentation,Data augmentation,Transfer learning Creator: Elsevier Producer: Acrobat Distiller 8.1.0 (Windows) CreationDate: Mon Sep 12 14:04:29 CEST 2022 ModDate: Sat Sep 17 18:12:52 CEST 2022 ID: 0xe79a8581892a683ebee8593603e0a957, 0xac07a5b8c1129283cbb557c8bb9779a8 Filters: FilterPipeline: FlateDecode Fonts: Type1: Font: BaseFont: EOSLZE+CharisSIL FontSubset: true FirstChar: 21 LastChar: 248 FontDescriptor: FontName: EOSLZE+CharisSIL Flags: Symbolic FontBBox: -1418, -1092, 6144, 2600 FontFile: true ToUnicode: true Font: BaseFont: OUILJB+u-charis-symbol FontSubset: true FirstChar: 32 LastChar: 42 FontDescriptor: FontName: OUILJB+u-charis-symbol Flags: Symbolic FontBBox: -40, -406, 1645, 1509 FontFile: true ToUnicode: true Font: BaseFont: EEFKWM+STIXMath-Regular FontSubset: true FirstChar: 42 LastChar: 227 FontDescriptor: FontName: EEFKWM+STIXMath-Regular Flags: Symbolic FontBBox: -970, -341, 1096, 1023 FontFile: true ToUnicode: true Font: BaseFont: EWWIMW+CharisSIL-Italic FontSubset: true FirstChar: 39 LastChar: 242 FontDescriptor: FontName: EWWIMW+CharisSIL-Italic Flags: Symbolic FontBBox: -1467, -1092, 6262, 2600 FontFile: true ToUnicode: true Font: BaseFont: TKLJNA+STIXMathScript-Regular FontSubset: true FirstChar: 12 LastChar: 12 FontDescriptor: FontName: TKLJNA+STIXMathScript-Regular Flags: Symbolic FontBBox: 0, -324, 1229, 830 FontFile: true ToUnicode: true Font: BaseFont: ABDNXX+STIXMath-Italic FontSubset: true FirstChar: 58 LastChar: 89 FontDescriptor: FontName: ABDNXX+STIXMath-Italic Flags: Symbolic FontBBox: -124, -478, 2328, 819 FontFile: true ToUnicode: true Font: BaseFont: LMYLQZ+CharisSIL-Bold FontSubset: true FirstChar: 45 LastChar: 237 FontDescriptor: FontName: LMYLQZ+CharisSIL-Bold Flags: Symbolic FontBBox: -1475, -1092, 6144, 2600 FontFile: true ToUnicode: true Font: BaseFont: AGQOEG+t1-uni-regular FontSubset: true FirstChar: 46 LastChar: 119 FontDescriptor: FontName: AGQOEG+t1-uni-regular Flags: Symbolic FontBBox: -168, -250, 992, 997 FontFile: true ToUnicode: true XMP: http://creativecommons.org/licenses/by/4.0/ elsevier.com sciencedirect.com true 10.1016/j.compbiomed.2022.106052 2010-04-23 application/pdf 10.1016/j.compbiomed.2022.106052 Elsevier Ltd Computers in Biology and Medicine, 149 (2022) 106052. doi:10.1016/j.compbiomed.2022.106052 Deep learning Contrast-enhanced imaging Domain generalization Cardiac image segmentation Data augmentation Transfer learning Domain generalization in deep learning for contrast-enhanced imaging Carla Sendra-Balcells Víctor M. Campello Carlos Martín-Isla David Viladés Martín L. Descalzo Andrea Guala José F. Rodríguez-Palomares Karim Lekadir VoR 17th September 2022 Acrobat Distiller 8.1.0 (Windows) Deep learning,Contrast-enhanced imaging,Domain generalization,Cardiac image segmentation,Data augmentation,Transfer learning 17th September 2022 sciencedirect.com elsevier.com true 2010-04-23 10.1016/j.compbiomed.2022.106052 noindex journal © 2022 The Author(s). Published by Elsevier Ltd. 2022-10-01 1 October 2022 10.1016/j.compbiomed.2022.106052 0010-4825 106052 Computers in Biology and Medicine 106052 https://doi.org/10.1016/j.compbiomed.2022.106052 149 2022-09-12T12:04:29 Elsevier 2022-09-17T16:12:52 2022-09-17T16:12:52 uuid:1b499bed-4ce8-4c0c-b682-0d58baae1cbe uuid:b6ed5266-03cb-4855-90c0-636283357f42 True Pages: Page: Label: 1 Annotations: Annotation: Subtype: Link Rect: 321, 724, 369, 730 Flags: Print Annotation: Subtype: Link Rect: 262, 668, 409, 675 Flags: Print Annotation: Subtype: Link Rect: 137, 602, 141, 605 Flags: Print ActionDest: 754 Annotation: Subtype: Link Rect: 143, 603, 147, 606 Flags: Print ActionDest: 754 Annotation: Subtype: Link Rect: 149, 600, 153, 607 Flags: Print ActionDest: 754 Annotation: Subtype: Link Rect: 251, 602, 254, 605 Flags: Print ActionDest: 754 Annotation: Subtype: Link Rect: 257, 600, 261, 607 Flags: Print ActionDest: 754 Annotation: Subtype: Link Rect: 352, 602, 355, 605 Flags: Print ActionDest: 754 Annotation: Subtype: Link Rect: 427, 602, 431, 607 Flags: Print ActionDest: 754 Annotation: Subtype: Link Rect: 125, 589, 129, 594 Flags: Print ActionDest: 754 Annotation: Subtype: Link Rect: 200, 589, 204, 592 Flags: Print ActionDest: 754 Annotation: Subtype: Link Rect: 345, 589, 348, 592 Flags: Print ActionDest: 754 Annotation: Subtype: Link Rect: 422, 589, 426, 592 Flags: Print ActionDest: 754 Annotation: Subtype: Link Rect: 223, 241, 228, 246 Flags: Print ActionDest: 227 Annotation: Subtype: Link Rect: 97, 220, 102, 225 Flags: Print ActionDest: 227 Annotation: Subtype: Link Rect: 104, 112, 171, 122 Flags: Print Annotation: Subtype: Link Rect: 374, 274, 379, 280 Flags: Print ActionDest: 227 Annotation: Subtype: Link Rect: 440, 232, 444, 238 Flags: Print ActionDest: 227 Annotation: Subtype: Link Rect: 395, 221, 400, 227 Flags: Print ActionDest: 227 Annotation: Subtype: Link Rect: 509, 211, 514, 216 Flags: Print ActionDest: 227 Annotation: Subtype: Link Rect: 518, 211, 522, 216 Flags: Print ActionDest: 227 Annotation: Subtype: Link Rect: 343, 200, 348, 206 Flags: Print ActionDest: 227 Annotation: Subtype: Link Rect: 350, 200, 359, 206 Flags: Print ActionDest: 227 Annotation: Subtype: Link Rect: 442, 200, 451, 206 Flags: Print ActionDest: 227 Annotation: Subtype: Link Rect: 453, 200, 462, 206 Flags: Print ActionDest: 227 Annotation: Subtype: Link Rect: 37, 87, 207, 94 Flags: Print Annotation: Subtype: Link Rect: 208, 748, 386, 760 Annotation: Subtype: Link Rect: 499, 616, 528, 645 Annotation: Subtype: Link Rect: 406, 57, 552, 69 Page: Label: 2 Annotations: Annotation: Subtype: Link Rect: 91, 457, 100, 463 Flags: Print ActionDest: 227 Annotation: Subtype: Link Rect: 202, 457, 211, 463 Flags: Print ActionDest: 227 Annotation: Subtype: Link Rect: 276, 457, 285, 463 Flags: Print ActionDest: 227 Annotation: Subtype: Link Rect: 64, 426, 73, 431 Flags: Print ActionDest: 227 Annotation: Subtype: Link Rect: 138, 426, 147, 431 Flags: Print ActionDest: 227 Annotation: Subtype: Link Rect: 195, 426, 204, 431 Flags: Print ActionDest: 227 Annotation: Subtype: Link Rect: 259, 426, 268, 431 Flags: Print ActionDest: 227 Annotation: Subtype: Link Rect: 81, 415, 90, 421 Flags: Print ActionDest: 227 Annotation: Subtype: Link Rect: 267, 320, 280, 328 Flags: Print ActionDest: 1 Annotation: Subtype: Link Rect: 284, 320, 288, 328 Flags: Print ActionDest: 1 Annotation: Subtype: Link Rect: 135, 126, 144, 131 Flags: Print ActionDest: 367 Annotation: Subtype: Link Rect: 65, 94, 74, 100 Flags: Print ActionDest: 367 Annotation: Subtype: Link Rect: 78, 94, 87, 100 Flags: Print ActionDest: 367 Annotation: Subtype: Link Rect: 306, 346, 319, 354 Flags: Print ActionDest: 42 Annotation: Subtype: Link Rect: 322, 346, 326, 354 Flags: Print ActionDest: 42 Annotation: Subtype: Link Rect: 387, 146, 407, 154 Flags: Print ActionDest: 42 Annotation: Subtype: Link Rect: 410, 146, 415, 154 Flags: Print ActionDest: 42 Annotation: Subtype: Link Rect: 477, 94, 490, 101 Flags: Print ActionDest: 1 Annotation: Subtype: Link Rect: 492, 94, 497, 101 Flags: Print ActionDest: 1 Page: Label: 3 Annotations: Annotation: Subtype: Link Rect: 99, 385, 108, 390 Flags: Print ActionDest: 367 Annotation: Subtype: Link Rect: 194, 240, 203, 245 Flags: Print ActionDest: 367 Annotation: Subtype: Link Rect: 206, 240, 215, 245 Flags: Print ActionDest: 367 Annotation: Subtype: Link Rect: 360, 229, 373, 236 Flags: Print ActionDest: 42 Annotation: Subtype: Link Rect: 378, 229, 382, 236 Flags: Print ActionDest: 42 Annotation: Subtype: Link Rect: 470, 156, 483, 164 Flags: Print ActionDest: 63 Annotation: Subtype: Link Rect: 487, 156, 492, 164 Flags: Print ActionDest: 63 Page: Label: 4 Annotations: Annotation: Subtype: Link Rect: 133, 147, 146, 154 Flags: Print ActionDest: 42 Annotation: Subtype: Link Rect: 149, 147, 153, 154 Flags: Print ActionDest: 42 Annotation: Subtype: Link Rect: 161, 147, 181, 154 Flags: Print ActionDest: 63 Annotation: Subtype: Link Rect: 184, 147, 188, 154 Flags: Print ActionDest: 63 Annotation: Subtype: Link Rect: 239, 51, 252, 59 Flags: Print ActionDest: 42 Annotation: Subtype: Link Rect: 254, 51, 259, 59 Flags: Print ActionDest: 42 Annotation: Subtype: Link Rect: 386, 214, 399, 221 Flags: Print ActionDest: 90 Annotation: Subtype: Link Rect: 402, 214, 407, 221 Flags: Print ActionDest: 90 Annotation: Subtype: Link Rect: 379, 161, 388, 167 Flags: Print ActionDest: 367 Annotation: Subtype: Link Rect: 398, 127, 411, 134 Flags: Print ActionDest: 90 Annotation: Subtype: Link Rect: 413, 127, 418, 134 Flags: Print ActionDest: 90 Annotation: Subtype: Link Rect: 339, 83, 359, 91 Flags: Print ActionDest: 90 Annotation: Subtype: Link Rect: 361, 83, 365, 91 Flags: Print ActionDest: 90 Page: Label: 5 Annotations: Annotation: Subtype: Link Rect: 91, 246, 104, 253 Flags: Print ActionDest: 42 Annotation: Subtype: Link Rect: 109, 246, 113, 253 Flags: Print ActionDest: 42 Annotation: Subtype: Link Rect: 221, 236, 230, 242 Flags: Print ActionDest: 367 Annotation: Subtype: Link Rect: 500, 248, 513, 255 Flags: Print ActionDest: 42 Annotation: Subtype: Link Rect: 517, 248, 522, 255 Flags: Print ActionDest: 42 Annotation: Subtype: Link Rect: 338, 138, 358, 146 Flags: Print ActionDest: 90 Annotation: Subtype: Link Rect: 361, 138, 366, 146 Flags: Print ActionDest: 90 Page: Label: 6 Annotations: Annotation: Subtype: Link Rect: 135, 475, 144, 481 Flags: Print ActionDest: 367 Annotation: Subtype: Link Rect: 266, 389, 279, 396 Flags: Print ActionDest: 109 Annotation: Subtype: Link Rect: 281, 389, 286, 396 Flags: Print ActionDest: 109 Annotation: Subtype: Link Rect: 318, 549, 338, 557 Flags: Print ActionDest: 141 Annotation: Subtype: Link Rect: 342, 549, 347, 557 Flags: Print ActionDest: 141 Annotation: Subtype: Link Rect: 363, 456, 376, 463 Flags: Print ActionDest: 141 Annotation: Subtype: Link Rect: 378, 456, 383, 463 Flags: Print ActionDest: 141 Annotation: Subtype: Link Rect: 316, 363, 330, 370 Flags: Print ActionDest: 141 Annotation: Subtype: Link Rect: 333, 363, 337, 370 Flags: Print ActionDest: 141 Annotation: Subtype: Link Rect: 534, 196, 547, 204 Flags: Print ActionDest: 141 Annotation: Subtype: Link Rect: 550, 196, 555, 204 Flags: Print ActionDest: 141 Annotation: Subtype: Link Rect: 537, 72, 550, 79 Flags: Print ActionDest: 167 Annotation: Subtype: Link Rect: 553, 72, 557, 79 Flags: Print ActionDest: 167 Page: Label: 7 Annotations: Annotation: Subtype: Link Rect: 96, 236, 109, 243 Flags: Print ActionDest: 167 Annotation: Subtype: Link Rect: 112, 236, 116, 243 Flags: Print ActionDest: 167 Annotation: Subtype: Link Rect: 161, 113, 174, 120 Flags: Print ActionDest: 167 Annotation: Subtype: Link Rect: 177, 113, 186, 120 Flags: Print ActionDest: 167 Annotation: Subtype: Link Rect: 533, 226, 546, 233 Flags: Print ActionDest: 167 Annotation: Subtype: Link Rect: 548, 226, 557, 233 Flags: Print ActionDest: 167 Annotation: Subtype: Link Rect: 493, 61, 506, 69 Flags: Print ActionDest: 191 Annotation: Subtype: Link Rect: 511, 61, 520, 69 Flags: Print ActionDest: 191 Page: Label: 8 Page: Label: 9 Annotations: Annotation: Subtype: Link Rect: 399, 542, 415, 548 Flags: Print ActionDest: 141 Annotation: Subtype: Link Rect: 418, 542, 421, 548 Flags: Print ActionDest: 141 Annotation: Subtype: Link Rect: 270, 198, 274, 203 Flags: Print ActionDest: 227 Annotation: Subtype: Link Rect: 274, 74, 283, 79 Flags: Print ActionDest: 367 Page: Label: 10 Annotations: Annotation: Subtype: Link Rect: 261, 114, 275, 121 Flags: Print ActionDest: 191 Annotation: Subtype: Link Rect: 279, 114, 288, 121 Flags: Print ActionDest: 191 Page: Label: 11 Annotations: Annotation: Subtype: Link Rect: 164, 666, 177, 673 Flags: Print ActionDest: 210 Annotation: Subtype: Link Rect: 180, 666, 189, 673 Flags: Print ActionDest: 210 Annotation: Subtype: Link Rect: 80, 625, 84, 631 Flags: Print ActionDest: 227 Annotation: Subtype: Link Rect: 202, 581, 215, 589 Flags: Print ActionDest: 210 Annotation: Subtype: Link Rect: 218, 581, 227, 589 Flags: Print ActionDest: 210 Annotation: Subtype: Link Rect: 325, 646, 557, 652 Flags: Print Annotation: Subtype: Link Rect: 306, 646, 306, 647 Flags: Print Annotation: Subtype: Link Rect: 325, 637, 385, 643 Flags: Print Annotation: Subtype: Link Rect: 325, 628, 557, 634 Flags: Print Annotation: Subtype: Link Rect: 306, 628, 306, 629 Flags: Print Annotation: Subtype: Link Rect: 325, 619, 557, 625 Flags: Print Annotation: Subtype: Link Rect: 325, 610, 557, 615 Flags: Print Annotation: Subtype: Link Rect: 306, 610, 306, 611 Flags: Print Annotation: Subtype: Link Rect: 325, 600, 557, 606 Flags: Print Annotation: Subtype: Link Rect: 306, 600, 306, 602 Flags: Print Annotation: Subtype: Link Rect: 325, 591, 557, 597 Flags: Print Annotation: Subtype: Link Rect: 306, 591, 306, 593 Flags: Print Annotation: Subtype: Link Rect: 325, 582, 350, 588 Flags: Print Annotation: Subtype: Link Rect: 325, 573, 557, 579 Flags: Print Annotation: Subtype: Link Rect: 306, 573, 306, 574 Flags: Print Annotation: Subtype: Link Rect: 325, 564, 557, 570 Flags: Print Annotation: Subtype: Link Rect: 306, 564, 306, 565 Flags: Print Annotation: Subtype: Link Rect: 325, 555, 557, 561 Flags: Print Annotation: Subtype: Link Rect: 306, 555, 306, 556 Flags: Print Annotation: Subtype: Link Rect: 325, 546, 418, 552 Flags: Print Annotation: Subtype: Link Rect: 325, 536, 557, 542 Flags: Print Annotation: Subtype: Link Rect: 306, 536, 306, 538 Flags: Print Annotation: Subtype: Link Rect: 325, 527, 557, 533 Flags: Print Annotation: Subtype: Link Rect: 306, 527, 306, 529 Flags: Print Annotation: Subtype: Link Rect: 325, 518, 557, 524 Flags: Print Annotation: Subtype: Link Rect: 306, 518, 306, 520 Flags: Print Annotation: Subtype: Link Rect: 325, 509, 557, 515 Flags: Print Annotation: Subtype: Link Rect: 306, 509, 306, 511 Flags: Print Annotation: Subtype: Link Rect: 325, 502, 352, 506 Flags: Print Annotation: Subtype: Link Rect: 325, 491, 557, 497 Flags: Print Annotation: Subtype: Link Rect: 306, 491, 306, 492 Flags: Print Annotation: Subtype: Link Rect: 325, 482, 557, 488 Flags: Print Annotation: Subtype: Link Rect: 306, 482, 306, 483 Flags: Print Annotation: Subtype: Link Rect: 325, 473, 557, 479 Flags: Print Annotation: Subtype: Link Rect: 306, 473, 306, 474 Flags: Print Annotation: Subtype: Link Rect: 325, 464, 363, 470 Flags: Print Annotation: Subtype: Link Rect: 325, 454, 557, 460 Flags: Print Annotation: Subtype: Link Rect: 306, 454, 306, 456 Flags: Print Annotation: Subtype: Link Rect: 325, 445, 557, 451 Flags: Print Annotation: Subtype: Link Rect: 306, 445, 306, 447 Flags: Print Annotation: Subtype: Link Rect: 325, 436, 557, 442 Flags: Print Annotation: Subtype: Link Rect: 306, 436, 306, 438 Flags: Print Annotation: Subtype: Link Rect: 325, 427, 557, 433 Flags: Print Annotation: Subtype: Link Rect: 306, 427, 306, 428 Flags: Print Annotation: Subtype: Link Rect: 325, 418, 476, 424 Flags: Print Annotation: Subtype: Link Rect: 325, 409, 557, 415 Flags: Print Annotation: Subtype: Link Rect: 306, 409, 306, 410 Flags: Print Annotation: Subtype: Link Rect: 325, 400, 557, 405 Flags: Print Annotation: Subtype: Link Rect: 306, 400, 306, 401 Flags: Print Annotation: Subtype: Link Rect: 325, 390, 557, 396 Flags: Print Annotation: Subtype: Link Rect: 306, 390, 306, 392 Flags: Print Annotation: Subtype: Link Rect: 325, 381, 382, 387 Flags: Print Annotation: Subtype: Link Rect: 325, 372, 557, 378 Flags: Print Annotation: Subtype: Link Rect: 306, 372, 306, 374 Flags: Print Annotation: Subtype: Link Rect: 325, 363, 557, 369 Flags: Print Annotation: Subtype: Link Rect: 306, 363, 306, 364 Flags: Print Annotation: Subtype: Link Rect: 325, 354, 509, 360 Flags: Print Annotation: Subtype: Link Rect: 325, 345, 557, 351 Flags: Print Annotation: Subtype: Link Rect: 306, 345, 306, 346 Flags: Print Annotation: Subtype: Link Rect: 325, 336, 557, 341 Flags: Print Annotation: Subtype: Link Rect: 306, 336, 306, 337 Flags: Print Annotation: Subtype: Link Rect: 325, 326, 539, 332 Flags: Print Annotation: Subtype: Link Rect: 325, 317, 557, 323 Flags: Print Annotation: Subtype: Link Rect: 306, 317, 306, 319 Flags: Print Annotation: Subtype: Link Rect: 325, 308, 557, 314 Flags: Print Annotation: Subtype: Link Rect: 306, 308, 306, 309 Flags: Print Annotation: Subtype: Link Rect: 325, 299, 368, 305 Flags: Print Annotation: Subtype: Link Rect: 325, 290, 557, 296 Flags: Print Annotation: Subtype: Link Rect: 306, 290, 306, 291 Flags: Print Annotation: Subtype: Link Rect: 325, 281, 557, 286 Flags: Print Annotation: Subtype: Link Rect: 306, 281, 306, 282 Flags: Print Annotation: Subtype: Link Rect: 325, 272, 443, 277 Flags: Print Annotation: Subtype: Link Rect: 325, 262, 557, 268 Flags: Print Annotation: Subtype: Link Rect: 306, 262, 306, 264 Flags: Print Annotation: Subtype: Link Rect: 325, 253, 557, 259 Flags: Print Annotation: Subtype: Link Rect: 306, 253, 306, 254 Flags: Print Annotation: Subtype: Link Rect: 325, 244, 493, 250 Flags: Print Annotation: Subtype: Link Rect: 457, 216, 557, 222 Flags: Print Annotation: Subtype: Link Rect: 306, 216, 306, 218 Flags: Print Annotation: Subtype: Link Rect: 325, 209, 363, 213 Flags: Print Annotation: Subtype: Link Rect: 325, 198, 557, 204 Flags: Print Annotation: Subtype: Link Rect: 306, 198, 306, 200 Flags: Print Annotation: Subtype: Link Rect: 325, 189, 397, 195 Flags: Print Annotation: Subtype: Link Rect: 325, 180, 557, 186 Flags: Print Annotation: Subtype: Link Rect: 306, 180, 306, 181 Flags: Print Annotation: Subtype: Link Rect: 325, 171, 557, 177 Flags: Print Annotation: Subtype: Link Rect: 306, 171, 306, 172 Flags: Print Annotation: Subtype: Link Rect: 325, 162, 363, 167 Flags: Print Annotation: Subtype: Link Rect: 325, 152, 557, 158 Flags: Print Annotation: Subtype: Link Rect: 306, 152, 306, 154 Flags: Print Annotation: Subtype: Link Rect: 325, 143, 529, 149 Flags: Print Annotation: Subtype: Link Rect: 325, 134, 557, 140 Flags: Print Annotation: Subtype: Link Rect: 306, 134, 306, 135 Flags: Print Annotation: Subtype: Link Rect: 325, 125, 557, 131 Flags: Print Annotation: Subtype: Link Rect: 306, 125, 306, 126 Flags: Print Annotation: Subtype: Link Rect: 325, 116, 557, 122 Flags: Print Annotation: Subtype: Link Rect: 306, 116, 306, 117 Flags: Print Annotation: Subtype: Link Rect: 325, 107, 440, 112 Flags: Print Annotation: Subtype: Link Rect: 325, 97, 557, 103 Flags: Print Annotation: Subtype: Link Rect: 306, 97, 306, 99 Flags: Print Annotation: Subtype: Link Rect: 325, 88, 487, 94 Flags: Print Annotation: Subtype: Link Rect: 325, 79, 557, 85 Flags: Print Annotation: Subtype: Link Rect: 306, 79, 306, 80 Flags: Print Annotation: Subtype: Link Rect: 325, 70, 557, 76 Flags: Print Annotation: Subtype: Link Rect: 306, 70, 306, 71 Flags: Print Annotation: Subtype: Link Rect: 325, 61, 557, 67 Flags: Print Annotation: Subtype: Link Rect: 306, 61, 306, 62 Flags: Print Annotation: Subtype: Link Rect: 325, 52, 538, 57 Flags: Print Page: Label: 12 Annotations: Annotation: Subtype: Link Rect: 56, 730, 288, 736 Flags: Print Annotation: Subtype: Link Rect: 37, 730, 37, 732 Flags: Print Annotation: Subtype: Link Rect: 56, 721, 288, 727 Flags: Print Annotation: Subtype: Link Rect: 37, 721, 37, 722 Flags: Print Annotation: Subtype: Link Rect: 56, 712, 104, 718 Flags: Print Annotation: Subtype: Link Rect: 56, 703, 288, 709 Flags: Print Annotation: Subtype: Link Rect: 37, 703, 37, 704 Flags: Print Annotation: Subtype: Link Rect: 56, 694, 288, 700 Flags: Print Annotation: Subtype: Link Rect: 37, 694, 37, 695 Flags: Print Annotation: Subtype: Link Rect: 56, 685, 288, 691 Flags: Print Annotation: Subtype: Link Rect: 37, 685, 37, 686 Flags: Print Annotation: Subtype: Link Rect: 56, 676, 141, 682 Flags: Print Annotation: Subtype: Link Rect: 56, 667, 288, 673 Flags: Print Annotation: Subtype: Link Rect: 37, 667, 37, 668 Flags: Print Annotation: Subtype: Link Rect: 56, 658, 288, 664 Flags: Print Annotation: Subtype: Link Rect: 37, 658, 37, 659 Flags: Print Annotation: Subtype: Link Rect: 56, 648, 288, 654 Flags: Print Annotation: Subtype: Link Rect: 37, 648, 37, 650 Flags: Print Annotation: Subtype: Link Rect: 56, 640, 112, 645 Flags: Print Annotation: Subtype: Link Rect: 56, 630, 288, 636 Flags: Print Annotation: Subtype: Link Rect: 37, 630, 37, 632 Flags: Print Annotation: Subtype: Link Rect: 56, 621, 288, 627 Flags: Print Annotation: Subtype: Link Rect: 37, 621, 37, 623 Flags: Print Annotation: Subtype: Link Rect: 56, 612, 288, 618 Flags: Print Annotation: Subtype: Link Rect: 37, 612, 37, 614 Flags: Print Annotation: Subtype: Link Rect: 56, 604, 102, 609 Flags: Print Annotation: Subtype: Link Rect: 182, 567, 233, 573 Flags: Print Annotation: Subtype: Link Rect: 325, 730, 557, 736 Flags: Print Annotation: Subtype: Link Rect: 306, 730, 306, 732 Flags: Print Annotation: Subtype: Link Rect: 325, 721, 557, 727 Flags: Print Annotation: Subtype: Link Rect: 306, 721, 306, 722 Flags: Print Annotation: Subtype: Link Rect: 325, 712, 557, 718 Flags: Print Annotation: Subtype: Link Rect: 306, 712, 306, 713 Flags: Print Annotation: Subtype: Link Rect: 325, 703, 403, 709 Flags: Print Annotation: Subtype: Link Rect: 325, 694, 557, 700 Flags: Print Annotation: Subtype: Link Rect: 306, 694, 306, 695 Flags: Print Annotation: Subtype: Link Rect: 325, 685, 557, 691 Flags: Print Annotation: Subtype: Link Rect: 306, 685, 306, 686 Flags: Print Annotation: Subtype: Link Rect: 325, 676, 505, 682 Flags: Print Annotation: Subtype: Link Rect: 325, 667, 557, 673 Flags: Print Annotation: Subtype: Link Rect: 306, 667, 306, 668 Flags: Print Annotation: Subtype: Link Rect: 325, 658, 557, 664 Flags: Print Annotation: Subtype: Link Rect: 306, 658, 306, 659 Flags: Print Annotation: Subtype: Link Rect: 325, 650, 359, 654 Flags: Print Annotation: Subtype: Link Rect: 325, 612, 557, 618 Flags: Print Annotation: Subtype: Link Rect: 306, 612, 306, 614 Flags: Print Annotation: Subtype: Link Rect: 325, 603, 557, 609 Flags: Print Annotation: Subtype: Link Rect: 306, 603, 306, 605 Flags: Print Annotation: Subtype: Link Rect: 325, 594, 552, 600 Flags: Print Annotation: Subtype: Link Rect: 325, 585, 557, 591 Flags: Print Annotation: Subtype: Link Rect: 306, 585, 306, 586 Flags: Print Annotation: Subtype: Link Rect: 325, 576, 557, 582 Flags: Print Annotation: Subtype: Link Rect: 306, 576, 306, 577 Flags: Print Annotation: Subtype: Link Rect: 325, 567, 443, 573 Flags: Print Annotation: Subtype: Link Rect: 325, 558, 557, 564 Flags: Print Annotation: Subtype: Link Rect: 306, 558, 306, 559 Flags: Print Annotation: Subtype: Link Rect: 325, 549, 534, 555 Flags: Print Checksum: 0a0d132f Type: CRC32 Checksum: 81b8425185e326685722f3bd5c12cc6f Type: MD5 Checksum: 5eaee0bed50aa46daf1f7b312f85f810cc6c5d50 Type: SHA-1 Checksum: 860aa39d3acfa17bc383cd448c61674af68a191daedbffbdbac5fbe08f169f04 Type: SHA-256