0f19d5b8e84f4ec5f647e996ec9d0f62 290548.pdf 661bf515240faedcb00706bd4513a8d2cf2997ac 290548.pdf e6a1e9649ceee97925ee5a23c203b0dc569f4a3bd708e31322879ac56b1d3a2f 290548.pdf Title: Can Breastfeeding Protect from Multi-System Inflammatory Syndrome in Children (MIS-C)? A Preliminary Study Subject: Background: Breastfeeding prevents Kawasaki disease (KD), as well as several autoimmune disorders. Since there is an overlap between the Multi-System Inflammatory Syndrome in children following SARS-CoV-2 infection (MIS-C) and KD, this case series aims to analyze the association between breastfeeding and MIS-C. Methods: A series of 16 cases of children with MIS-C admitted to three pediatric facilities between January 2021 and May 2022 were conducted. Breastfeeding rate was estimated through the Brief Breastfeeding and Milk Expression Recall Survey. Results: Out of 16 children, 9 (56%) had been breastfed at birth. Discussion: Our breastfeeding rate is below the median Spanish rate for initial breastfeeding. These findings do not clearly support the hypothesis that breastfeeding might prevent MIS-C. Conclusion: Contrary to the role of breastfeeding in KD prevention, our case series cannot answer with certainty the question about whether or not breastfeeding does protect children against MIS-C. These findings require confirmation in larger studies. Keywords: COVID-19; breastfeeding; Kawasaki disease; autoimmune diseases; infant formula Author: Xavier Rodríguez-Fanjul, Sergio Verd and Sonia Brio Creator: LaTeX with hyperref Producer: pdfTeX-1.40.21 CreationDate: Wed Aug 3 02:35:54 2022 CEST ModDate: Wed Aug 3 02:41:18 2022 CEST Custom Metadata: no Metadata Stream: no Tagged: no UserProperties: no Suspects: no Form: none JavaScript: no Pages: 4 Encrypted: no Page size: 595.276 x 841.89 pts (A4) Page rot: 0 File size: 228932 bytes Optimized: no PDF version: 1.7 name type encoding emb sub uni object ID ------------------------------------ ----------------- ---------------- --- --- --- --------- ATOCZH+URWPalladioL-Bold Type 1 Custom yes yes no 10 0 VCUQZQ+URWPalladioL-Roma Type 1 Custom yes yes no 15 0 HPFYUZ+URWPalladioL-Ital Type 1 Custom yes yes no 19 0 LWLIVD+EURM10 Type 1 Builtin yes yes no 23 0 WLENKM+VnURWPalladioL-Bold Type 1 Custom yes yes no 27 0 YJPPHJ+TimesNewRomanPS-BoldItalicMT Type 1C WinAnsi yes yes no 46 0 WBVKDJ+URWPalladioL-BoldItal Type 1 Custom yes yes no 71 0 RYQMUY+VnURWPalladioL Type 1 Custom yes yes no 78 0 Jhove (Rel. 1.28.0, 2023-05-18) Date: 2024-04-12 02:43:23 CEST RepresentationInformation: 290548.pdf ReportingModule: PDF-hul, Rel. 1.12.4 (2023-03-16) LastModified: 2024-04-11 13:19:10 CEST Size: 228932 Format: PDF Version: 1.7 Status: Well-Formed and valid SignatureMatches: PDF-hul MIMEtype: application/pdf PDFMetadata: Objects: 144 FreeObjects: 1 IncrementalUpdates: 0 DocumentCatalog: PageLayout: SinglePage PageMode: UseNone Outlines: Item: Title: Introduction Destination: section.1 Item: Title: Methods Destination: section.2 Item: Title: Results Destination: section.3 Item: Title: Discussion Destination: section.4 Item: Title: Conclusions Destination: section.5 Item: Title: References Destination: section.5 Info: Title: Can Breastfeeding Protect from Multi-System Inflammatory Syndrome in Children (MIS-C)? A Preliminary Study Author: Xavier Rodríguez-Fanjul, Sergio Verd and Sonia Brio Subject: Background: Breastfeeding prevents Kawasaki disease (KD), as well as several autoimmune disorders. Since there is an overlap between the Multi-System Inflammatory Syndrome in children following SARS-CoV-2 infection (MIS-C) and KD, this case series aims to analyze the association between breastfeeding and MIS-C. Methods: A series of 16 cases of children with MIS-C admitted to three pediatric facilities between January 2021 and May 2022 were conducted. Breastfeeding rate was estimated through the Brief Breastfeeding and Milk Expression Recall Survey. Results: Out of 16 children, 9 (56%) had been breastfed at birth. Discussion: Our breastfeeding rate is below the median Spanish rate for initial breastfeeding. These findings do not clearly support the hypothesis that breastfeeding might prevent MIS-C. Conclusion: Contrary to the role of breastfeeding in KD prevention, our case series cannot answer with certainty the question about whether or not breastfeeding does protect children against MIS-C. These findings require confirmation in larger studies. 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