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Destination: mk:title Children: Item: Title: 1 Introduction Destination: mk:H1_1 Item: Title: 2 Material and methods Destination: mk:H1_2 Children: Item: Title: 2.1 Sample Destination: mk:H2_1 Item: Title: 2.2 Metabolic and environmental data assessment Destination: mk:H2_2 Item: Title: 2.3 Blood samples and genotyping Destination: mk:H2_3 Item: Title: 2.4 PRS calculation Destination: mk:H2_4 Item: Title: 2.5 Statistical analysis Destination: mk:H2_5 Item: Title: 3 Results Destination: mk:H1_3 Children: Item: Title: 3.1 Descriptive statistics Destination: mk:H2_6 Item: Title: 3.2 Basal metabolic status Destination: mk:H2_7 Item: Title: 3.3 Longitudinal analyses Destination: mk:H2_8 Item: Title: 4 Discussion Destination: mk:H1_4 Item: Title: 5 Conclusion Destination: mk:H1_5 Item: Title: Appendix A PEPs group Destination: mk:H1_6 Item: Title: References Destination: mk:HH2_1 Info: Title: Metabolic polygenic risk scores effect on antipsychotic-induced metabolic dysregulation: A longitudinal study in a first episode psychosis cohort Author: P Subject: Schizophrenia Research, 244 (2022) 101-110. doi:10.1016/j.schres.2022.05.021 Keywords: Psychotic disorders,Metabolic syndrome,Polygenic risk score Creator: Elsevier Producer: Acrobat Distiller 8.1.0 (Windows) CreationDate: Tue Jun 14 10:37:01 CEST 2022 ModDate: Wed Jun 15 03:20:23 CEST 2022 ID: 0xa7c7808a460f410b460f76fd0dc6050b, 0x1f16b5ac97959128752b8896d41cbaac Filters: FilterPipeline: FlateDecode FilterPipeline: DCTDecode Images: Image: NisoImageMetadata: FormatName: image/jpg CompressionScheme: JPEG ImageWidth: 236 ImageHeight: 298 BitsPerSample: 8 BitsPerSampleUnit: integer Image: NisoImageMetadata: FormatName: image/jpg CompressionScheme: JPEG ImageWidth: 248 ImageHeight: 271 BitsPerSample: 8 BitsPerSampleUnit: integer Fonts: Type0: Font: BaseFont: KXZBDV+TimesNewRomanPSMT Encoding: Identity-H ToUnicode: true Font: BaseFont: AULNZM+CharisSIL Encoding: Identity-H ToUnicode: true Font: BaseFont: WCBXTY+CharisSIL-Italic Encoding: Identity-H ToUnicode: true Font: BaseFont: VZDUVQ+CharisSIL-Bold Encoding: Identity-H ToUnicode: true Type1: Font: BaseFont: VVCCGG+TeX_CM_Maths_Italic FontSubset: true FirstChar: 1 LastChar: 127 FontDescriptor: FontName: VVCCGG+TeX_CM_Maths_Italic Flags: Symbolic FontBBox: -50, -180, 1000, 720 FontFile3: true ToUnicode: true Font: BaseFont: EVZLMV+TeX_CM_Roman FontSubset: true FirstChar: 1 LastChar: 128 FontDescriptor: FontName: EVZLMV+TeX_CM_Roman Flags: Symbolic FontBBox: -50, -180, 1000, 720 FontFile3: true ToUnicode: true Font: BaseFont: THGZGT+STIX-Regular FontSubset: true FirstChar: 1 LastChar: 9 FontDescriptor: FontName: THGZGT+STIX-Regular Flags: Nonsymbolic FontBBox: -970, -486, 2208, 1023 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true ToUnicode: true Font: BaseFont: GBNAGF+Univers FontSubset: true FirstChar: 32 LastChar: 251 FontDescriptor: FontName: GBNAGF+Univers Flags: Symbolic FontBBox: -50, -180, 1000, 720 FontFile3: true ToUnicode: true Font: BaseFont: LOKTVY+TeX_CM_Maths_Symbols FontSubset: true FirstChar: 1 LastChar: 138 FontDescriptor: FontName: LOKTVY+TeX_CM_Maths_Symbols Flags: Symbolic FontBBox: -50, -180, 1000, 720 FontFile3: true ToUnicode: true CIDFontType2: Font: BaseFont: KXZBDV+TimesNewRomanPSMT CIDSystemInfo: Registry: Adobe Registry: Identity Supplement: 0 FontDescriptor: FontName: KXZBDV+TimesNewRomanPSMT Flags: Nonsymbolic FontBBox: -568, -307, 2000, 1007 FontFile2: true Font: BaseFont: AULNZM+CharisSIL CIDSystemInfo: Registry: Adobe Registry: Identity Supplement: 0 FontDescriptor: FontName: AULNZM+CharisSIL Flags: Nonsymbolic FontBBox: -692, -533, 1623, 1319 FontFile2: true Font: BaseFont: WCBXTY+CharisSIL-Italic CIDSystemInfo: Registry: Adobe Registry: Identity Supplement: 0 FontDescriptor: FontName: WCBXTY+CharisSIL-Italic Flags: Nonsymbolic, Italic FontBBox: -716, -533, 1627, 1318 FontFile2: true Font: BaseFont: VZDUVQ+CharisSIL-Bold CIDSystemInfo: Registry: Adobe Registry: Identity Supplement: 0 FontDescriptor: FontName: VZDUVQ+CharisSIL-Bold Flags: Nonsymbolic, ForceBold FontBBox: -720, -533, 1759, 1320 FontFile2: true XMP: application/pdf 10.1016/j.schres.2022.05.021 Elsevier B.V. Schizophrenia Research, 244 (2022) 101-110. doi:10.1016/j.schres.2022.05.021 Psychotic disorders Metabolic syndrome Polygenic risk score Metabolic polygenic risk scores effect on antipsychotic-induced metabolic dysregulation: A longitudinal study in a first episode psychosis cohort P Àlex G. Segura Albert Martínez-Pinteño Patricia Gassó Natalia Rodríguez Miquel Bioque Manuel J. Cuesta Javier González-Peñas Clemente García-Rizo Antonio Lobo Ana González-Pinto Alicia García-Alcón Alexandra Roldán Eduard Vieta Josefina Castro-Fornieles Anna Mané Jeronimo Saiz Miguel Bernardo Sergi Mas journal Schizophrenia Research © 2022 The Authors. Published by Elsevier B.V. 0920-9964 244 1 June 2022 2022-06-01 101-110 101 110 10.1016/j.schres.2022.05.021 https://doi.org/10.1016/j.schres.2022.05.021 2010-04-23 true 10.1016/j.schres.2022.05.021 elsevier.com sciencedirect.com http://creativecommons.org/licenses/by-nc-nd/4.0/ VoR 10.1016/j.schres.2022.05.021 noindex 2010-04-23 true 15th June 2022 sciencedirect.com elsevier.com Elsevier 2022-06-15T01:20:23 2022-06-14T08:37:01 2022-06-15T01:20:23 True 15th June 2022 Acrobat Distiller 8.1.0 (Windows) Psychotic disorders,Metabolic syndrome,Polygenic risk score uuid:1b499bed-4ce8-4c0c-b682-0d58baae1cbe uuid:b6ed5266-03cb-4855-90c0-636283357f42 Pages: Page: Label: 101 Sequence: 1 Annotations: Annotation: Subtype: Link Rect: 109, 576, 319, 587 Flags: Print Destination: 718 Annotation: Subtype: Link Rect: 320, 576, 327, 587 Flags: Print Destination: 718 Annotation: Subtype: Link Rect: 327, 571, 424, 582 Flags: Print Destination: 718 Annotation: Subtype: Link Rect: 424, 571, 431, 582 Flags: 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