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Status: Well-Formed, but not valid SignatureMatches: PDF-hul ErrorMessage: Invalid indirect destination - referenced object 'sec0105' cannot be found ID: PDF-HUL-149 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'sec0105' cannot be found ID: PDF-HUL-122 Offset: 3024913 MIMEtype: application/pdf Profile: Linearized PDF, Tagged PDF PDFMetadata: Objects: 994 FreeObjects: 1 IncrementalUpdates: 1 DocumentCatalog: PageLayout: SinglePage PageMode: UseOutlines Language: en Outlines: Item: Title: Antagonism of miR-148a attenuates atherosclerosis progression in APOBTGApobec-/-Ldlr+/- mice: A brief report Destination: mk:title Children: Item: Title: 1 Introduction Destination: mk:H1_1 Item: Title: 2 Materials and methods Destination: mk:H1_2 Children: Item: Title: 2.1 Animals and LNA 148a treatment Destination: mk:H2_1 Item: Title: 2.2 Lipoprotein profile and lipid measurements Destination: mk:H2_2 Item: Title: 2.3 Histology, immunohistochemistry, and morphometric analyses Destination: mk:H2_3 Item: Title: 2.4 En face ORO staining Destination: mk:H2_4 Item: Title: 2.5 Cell culture Destination: mk:H2_5 Item: Title: 2.6 Transfection with an miRNA mimic or an inhibitor Destination: mk:H2_6 Item: Title: 2.7 M1 and M2 polarization assay Destination: mk:H2_7 Item: Title: 2.8 Cholesterol efflux assays Destination: mk:H2_8 Item: Title: 2.9 Western blot analysis Destination: mk:H2_9 Item: Title: 2.10 RNA isolation and quantitative real-time polymerase chain reaction (qRT-PCR) Destination: mk:H2_10 Item: Title: 2.11 Analysis of circulating leukocytes Destination: mk:H2_11 Item: Title: 2.12 Statistical analysis Destination: mk:H2_12 Item: Title: 3 Results Destination: mk:H1_3 Item: Title: 4 Discussion Destination: mk:H1_4 Item: Title: Funding Destination: mk:H1_5 Item: Title: CRediT authorship contribution statement Destination: mk:H1_6 Item: Title: Disclosures Destination: mk:H1_7 Item: Title: Conflict of interest statement Destination: mk:HH1_2 Item: Title: Data Availability Destination: datalink3 Item: Title: Appendix A Supporting information Destination: mk:H1_8 Item: Title: References Destination: mk:HH2_1 Info: Title: Antagonism of miR-148a attenuates atherosclerosis progression in APOB TG Apobec -/- Ldlr +/- mice: A brief report Author: Noemi Rotllan Subject: Biomedicine & Pharmacotherapy, 153 (2022) 113419. doi:10.1016/j.biopha.2022.113419 Keywords: MiR-148a,Atherosclerosis progression,Therapeutic inhibition,Plaque stability,Cholesterol Efflux,M2-like phenotype Creator: Elsevier Producer: Acrobat Distiller 8.1.0 (Windows) CreationDate: Tue Aug 30 12:38:42 CEST 2022 ModDate: Tue Aug 30 12:49:02 CEST 2022 ID: 0x3d8c2caeabfe38765b08870a62613491, 0xd5630a21310c8ad9b44bbcda2dce4414 Filters: FilterPipeline: FlateDecode FilterPipeline: DCTDecode Images: Image: NisoImageMetadata: FormatName: image/jpg CompressionScheme: JPEG ImageWidth: 236 ImageHeight: 298 BitsPerSample: 8 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Masson SAS Biomedicine & Pharmacotherapy, 153 (2022) 113419. doi:10.1016/j.biopha.2022.113419 MiR-148a Atherosclerosis progression Therapeutic inhibition Plaque stability Cholesterol Efflux M2-like phenotype Antagonism of miR-148a attenuates atherosclerosis progression in APOB TG Apobec -/- Ldlr +/- mice: A brief report Noemi Rotllan Xinbo Zhang Alberto Canfrán-Duque Leigh Goedeke Raquel Griñán Cristina M. Ramírez Yajaira Suárez Carlos Fernández-Hernando VoR 30th August 2022 Acrobat Distiller 8.1.0 (Windows) MiR-148a,Atherosclerosis progression,Therapeutic inhibition,Plaque stability,Cholesterol Efflux,M2-like phenotype 30th August 2022 sciencedirect.com elsevier.com true 2010-04-23 10.1016/j.biopha.2022.113419 noindex journal © 2022 The Authors. 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