2b85f4c97f343231c84f8392a10b3c74  290600.pdf
3af2af2b5e995e5281b7da547fbfe957752be9e4  290600.pdf
76ce0a5d2a1f0d02dbc5ee48540647b1f18b8d9f8365f425251ea5b1df5e623d  290600.pdf

Title:           Assessing the value contribution of bimekizumab for the treatment of moderate-to-severe psoriasis us
Subject:         Expert Review of Pharmacoeconomics & Outcomes Research, 2022. doi:10.1080/14737167.2022.2063842
Keywords:        Psoriasis; moderate-to-severe; biologics; multi-criteria decision analysis; MCDA; bimekizumab
Author:          Néboa Zozaya
Creator:         Arbortext Advanced Print Publisher 11.0.3433/W Unicode
Producer:        PDFlib+PDI 9.0.3p4 (C++/Win32)
CreationDate:    Tue Sep  6 14:32:39 2022 CEST
ModDate:         Thu Apr 18 15:47:30 2024 CEST
Custom Metadata: yes
Metadata Stream: yes
Tagged:          no
UserProperties:  no
Suspects:        no
Form:            none
JavaScript:      no
Pages:           15
Encrypted:       no
Page size:       634.32 x 833.04 pts
Page rot:        0
File size:       3125478 bytes
Optimized:       yes
PDF version:     1.5


name                                 type              encoding         emb sub uni object ID
------------------------------------ ----------------- ---------------- --- --- --- ---------
EFGGIE+OpenSans                      CID TrueType      Identity-H       yes yes yes    749  0
EFGGIF+OpenSans-Semibold             CID TrueType      Identity-H       yes yes yes    753  0
CUNFJO+MyriadPro-Regular             Type 1C           Custom           yes yes yes    594  0
XJHPEG+MyriadPro-Semibold            Type 1C           Custom           yes yes yes    595  0
PECCOO+MyriadPro-SemiCn              Type 1C           Custom           yes yes yes    599  0
NKZSQL+MyriadPro-Black               Type 1C           Custom           yes yes yes    602  0
YXIXTG+MyriadPro-Bold                Type 1C           Custom           yes yes yes    605  0
CEVEYN+MyriadPro-BoldIt              Type 1C           Custom           yes yes yes    609  0
IEFJDD+MyriadPro-SemiCnIt            Type 1C           Custom           yes yes yes    613  0
NRPBKI+MyriadPro-It                  Type 1C           Custom           yes yes yes    627  0
TeX_CM_Maths_Symbols                 Type 1            Builtin          yes no  yes    624  0
TeX_CM_Maths_Extension               Type 1            Builtin          yes no  yes    621  0
NITMMP+MyriadPro-SemiboldSemiCn      Type 1C           Custom           yes yes yes    626  0
BYNZDN+MyriadPro-BoldSemiCn          Type 1C           Custom           yes yes yes    634  0
GODWOX+ArialUnicodeMS-Identity-H     CID TrueType      Identity-H       yes yes yes    632  0


Jhove (Rel. 1.28.0, 2023-05-18)
 Date: 2024-04-20 02:37:23 CEST
 RepresentationInformation: 290600.pdf
  ReportingModule: PDF-hul, Rel. 1.12.4 (2023-03-16)
  LastModified: 2024-04-18 15:49:34 CEST
  Size: 3125478
  Format: PDF
  Version: 1.5
  Status: Well-Formed and valid
  SignatureMatches:
   PDF-hul
  MIMEtype: application/pdf
  Profile: Linearized PDF
  PDFMetadata: 
   Objects: 0
   FreeObjects: 1
   IncrementalUpdates: 0
   DocumentCatalog: 
    PageLayout: SinglePage
    PageMode: UseNone
    Outlines: 
     Item: 
      Title: Abstract
      Destination: 1
     Item: 
      Title: 1.  Introduction
      Destination: 1
     Item: 
      Title: 2.  Methods
      Destination: 1
      Children: 
       Item: 
        Title: 2.1.  Expert panel design and conduct of the study
        Destination: 1
       Item: 
        Title: 2.2.  Literature review and evidence matrix
        Destination: 1
       Item: 
        Title: 2.3.  Data analysis
        Destination: 1
     Item: 
      Title: 3.  Results
      Destination: 1
      Children: 
       Item: 
        Title: 3.1.  Weights: relative importance of each criterion
        Destination: 1
       Item: 
        Title: 3.2.  Scores based on evidence and insights from the MEC
        Destination: 1
       Item: 
        Title: 3.3.  Value estimates: combining weights and scores
        Destination: 1
       Item: 
        Title: 3.4.  Replicability and consistency
        Destination: 1
     Item: 
      Title: 4.  Discussion
      Destination: 1
     Item: 
      Title: 5.  Conclusions
      Destination: 1
     Item: 
      Title: Authors contributions
      Destination: 1
     Item: 
      Title: List of abbreviations
      Destination: 1
     Item: 
      Title: Data availability statement
      Destination: 1
     Item: 
      Title: Funding
      Destination: 1
     Item: 
      Title: Declaration of interest
      Destination: 1
     Item: 
      Title: Reviewer disclosures
      Destination: 1
     Item: 
      Title: References
      Destination: 1
   Filters: 
    FilterPipeline: FlateDecode
    FilterPipeline: DCTDecode
   Images: 
    Image: 
     NisoImageMetadata: 
      FormatName: image/png
      ImageWidth: 600
      ImageHeight: 600
      BitsPerSample: 8
      BitsPerSampleUnit: integer
     Filter: FlateDecode
     ColorSpace: ICCBased
     Name: Im20
    Image: 
     NisoImageMetadata: 
      FormatName: image/png
      ImageWidth: 600
      ImageHeight: 641
      BitsPerSample: 8
      BitsPerSampleUnit: integer
     Filter: FlateDecode
     ColorSpace: ICCBased
     Name: Im10
    Image: 
     NisoImageMetadata: 
      FormatName: image/png
      ImageWidth: 600
      ImageHeight: 448
      ColorSpace: black is zero
      BitsPerSample: 8
      BitsPerSampleUnit: integer
     Filter: FlateDecode
     Name: Im13
    Image: 
     NisoImageMetadata: 
      FormatName: image/png
      ImageWidth: 600
      ImageHeight: 448
      BitsPerSample: 8
      BitsPerSampleUnit: integer
     Filter: FlateDecode
     ColorSpace: ICCBased
     Name: Im14
    Image: 
     NisoImageMetadata: 
      FormatName: image/png
      ImageWidth: 600
      ImageHeight: 470
      ColorSpace: black is zero
      BitsPerSample: 8
      BitsPerSampleUnit: integer
     Filter: FlateDecode
     Name: Im11
    Image: 
     NisoImageMetadata: 
      FormatName: image/png
      ImageWidth: 600
      ImageHeight: 470
      BitsPerSample: 8
      BitsPerSampleUnit: integer
     Filter: FlateDecode
     ColorSpace: ICCBased
     Name: Im12
    Image: 
     NisoImageMetadata: 
      FormatName: image/png
      ImageWidth: 600
      ImageHeight: 674
      ColorSpace: black is zero
      BitsPerSample: 8
      BitsPerSampleUnit: integer
     Filter: FlateDecode
     Name: Im17
    Image: 
     NisoImageMetadata: 
      FormatName: image/png
      ImageWidth: 600
      ImageHeight: 674
      BitsPerSample: 8
      BitsPerSampleUnit: integer
     Filter: FlateDecode
     ColorSpace: ICCBased
     Name: Im18
    Image: 
     NisoImageMetadata: 
      FormatName: image/png
      ImageWidth: 600
      ImageHeight: 694
      ColorSpace: black is zero
      BitsPerSample: 8
      BitsPerSampleUnit: integer
     Filter: FlateDecode
     Name: Im15
    Image: 
     NisoImageMetadata: 
      FormatName: image/png
      ImageWidth: 600
      ImageHeight: 694
      BitsPerSample: 8
      BitsPerSampleUnit: integer
     Filter: FlateDecode
     ColorSpace: ICCBased
     Name: Im16
    Image: 
     NisoImageMetadata: 
      FormatName: image/jpg
      CompressionScheme: JPEG
      ImageWidth: 200
      ImageHeight: 261
      BitsPerSample: 8
      BitsPerSampleUnit: integer
     ColorSpace: ICCBased
     Name: Im1
    Image: 
     NisoImageMetadata: 
      FormatName: image/png
      ImageWidth: 600
      ImageHeight: 600
      ColorSpace: black is zero
      BitsPerSample: 8
      BitsPerSampleUnit: integer
     Filter: FlateDecode
     Name: Im19
    Image: 
     NisoImageMetadata: 
      FormatName: image/png
      ImageWidth: 600
      ImageHeight: 1010
      ColorSpace: black is zero
      BitsPerSample: 8
      BitsPerSampleUnit: integer
     Filter: FlateDecode
     Name: Im3
    Image: 
     NisoImageMetadata: 
      FormatName: image/png
      ImageWidth: 3150
      ImageHeight: 746
      BitsPerSample: 8
      BitsPerSampleUnit: integer
     Filter: FlateDecode
     ColorSpace: ICCBased
     Name: Im2
    Image: 
     NisoImageMetadata: 
      FormatName: image/png
      ImageWidth: 600
      ImageHeight: 703
      ColorSpace: black is zero
      BitsPerSample: 8
      BitsPerSampleUnit: integer
     Filter: FlateDecode
     Name: Im5
    Image: 
     NisoImageMetadata: 
      FormatName: image/png
      ImageWidth: 600
      ImageHeight: 1010
      BitsPerSample: 8
      BitsPerSampleUnit: integer
     Filter: FlateDecode
     ColorSpace: ICCBased
     Name: Im4
    Image: 
     NisoImageMetadata: 
      FormatName: image/png
      ImageWidth: 512
      ImageHeight: 346
      ColorSpace: black is zero
      BitsPerSample: 8
      BitsPerSampleUnit: integer
     Filter: FlateDecode
     Name: Im7
    Image: 
     NisoImageMetadata: 
      FormatName: image/png
      ImageWidth: 600
      ImageHeight: 703
      BitsPerSample: 8
      BitsPerSampleUnit: integer
     Filter: FlateDecode
     ColorSpace: ICCBased
     Name: Im6
    Image: 
     NisoImageMetadata: 
      FormatName: image/png
      ImageWidth: 600
      ImageHeight: 641
      ColorSpace: black is zero
      BitsPerSample: 8
      BitsPerSampleUnit: integer
     Filter: FlateDecode
     Name: Im9
    Image: 
     NisoImageMetadata: 
      FormatName: image/png
      ImageWidth: 512
      ImageHeight: 346
      BitsPerSample: 8
      BitsPerSampleUnit: integer
     Filter: FlateDecode
     ColorSpace: ICCBased
     Name: Im8
    Image: 
     NisoImageMetadata: 
      FormatName: image/png
      ImageWidth: 600
      ImageHeight: 600
      BitsPerSample: 8
      BitsPerSampleUnit: integer
     Filter: FlateDecode
     ColorSpace: ICCBased
     Name: Im20
    Image: 
     NisoImageMetadata: 
      FormatName: image/png
      ImageWidth: 600
      ImageHeight: 641
      BitsPerSample: 8
      BitsPerSampleUnit: integer
     Filter: FlateDecode
     ColorSpace: ICCBased
     Name: Im10
    Image: 
     NisoImageMetadata: 
      FormatName: image/png
      ImageWidth: 600
      ImageHeight: 448
      ColorSpace: black is zero
      BitsPerSample: 8
      BitsPerSampleUnit: integer
     Filter: FlateDecode
     Name: Im13
    Image: 
     NisoImageMetadata: 
      FormatName: image/png
      ImageWidth: 600
      ImageHeight: 448
      BitsPerSample: 8
      BitsPerSampleUnit: integer
     Filter: FlateDecode
     ColorSpace: ICCBased
     Name: Im14
    Image: 
     NisoImageMetadata: 
      FormatName: image/png
      ImageWidth: 600
      ImageHeight: 470
      ColorSpace: black is zero
      BitsPerSample: 8
      BitsPerSampleUnit: integer
     Filter: FlateDecode
     Name: Im11
    Image: 
     NisoImageMetadata: 
      FormatName: image/png
      ImageWidth: 600
      ImageHeight: 470
      BitsPerSample: 8
      BitsPerSampleUnit: integer
     Filter: FlateDecode
     ColorSpace: ICCBased
     Name: Im12
    Image: 
     NisoImageMetadata: 
      FormatName: image/png
      ImageWidth: 600
      ImageHeight: 674
      ColorSpace: black is zero
      BitsPerSample: 8
      BitsPerSampleUnit: integer
     Filter: FlateDecode
     Name: Im17
    Image: 
     NisoImageMetadata: 
      FormatName: image/png
      ImageWidth: 600
      ImageHeight: 674
      BitsPerSample: 8
      BitsPerSampleUnit: integer
     Filter: FlateDecode
     ColorSpace: ICCBased
     Name: Im18
    Image: 
     NisoImageMetadata: 
      FormatName: image/png
      ImageWidth: 600
      ImageHeight: 694
      ColorSpace: black is zero
      BitsPerSample: 8
      BitsPerSampleUnit: integer
     Filter: FlateDecode
     Name: Im15
    Image: 
     NisoImageMetadata: 
      FormatName: image/png
      ImageWidth: 600
      ImageHeight: 694
      BitsPerSample: 8
      BitsPerSampleUnit: integer
     Filter: FlateDecode
     ColorSpace: ICCBased
     Name: Im16
    Image: 
     NisoImageMetadata: 
      FormatName: image/jpg
      CompressionScheme: JPEG
      ImageWidth: 200
      ImageHeight: 261
      BitsPerSample: 8
      BitsPerSampleUnit: integer
     ColorSpace: ICCBased
     Name: Im1
    Image: 
     NisoImageMetadata: 
      FormatName: image/png
      ImageWidth: 600
      ImageHeight: 600
      ColorSpace: black is zero
      BitsPerSample: 8
      BitsPerSampleUnit: integer
     Filter: FlateDecode
     Name: Im19
    Image: 
     NisoImageMetadata: 
      FormatName: image/png
      ImageWidth: 600
      ImageHeight: 1010
      ColorSpace: black is zero
      BitsPerSample: 8
      BitsPerSampleUnit: integer
     Filter: FlateDecode
     Name: Im3
    Image: 
     NisoImageMetadata: 
      FormatName: image/png
      ImageWidth: 3150
      ImageHeight: 746
      BitsPerSample: 8
      BitsPerSampleUnit: integer
     Filter: FlateDecode
     ColorSpace: ICCBased
     Name: Im2
    Image: 
     NisoImageMetadata: 
      FormatName: image/png
      ImageWidth: 600
      ImageHeight: 703
      ColorSpace: black is zero
      BitsPerSample: 8
      BitsPerSampleUnit: integer
     Filter: FlateDecode
     Name: Im5
    Image: 
     NisoImageMetadata: 
      FormatName: image/png
      ImageWidth: 600
      ImageHeight: 1010
      BitsPerSample: 8
      BitsPerSampleUnit: integer
     Filter: FlateDecode
     ColorSpace: ICCBased
     Name: Im4
    Image: 
     NisoImageMetadata: 
      FormatName: image/png
      ImageWidth: 512
      ImageHeight: 346
      ColorSpace: black is zero
      BitsPerSample: 8
      BitsPerSampleUnit: integer
     Filter: FlateDecode
     Name: Im7
    Image: 
     NisoImageMetadata: 
      FormatName: image/png
      ImageWidth: 600
      ImageHeight: 703
      BitsPerSample: 8
      BitsPerSampleUnit: integer
     Filter: FlateDecode
     ColorSpace: ICCBased
     Name: Im6
    Image: 
     NisoImageMetadata: 
      FormatName: image/png
      ImageWidth: 600
      ImageHeight: 641
      ColorSpace: black is zero
      BitsPerSample: 8
      BitsPerSampleUnit: integer
     Filter: FlateDecode
     Name: Im9
    Image: 
     NisoImageMetadata: 
      FormatName: image/png
      ImageWidth: 512
      ImageHeight: 346
      BitsPerSample: 8
      BitsPerSampleUnit: integer
     Filter: FlateDecode
     ColorSpace: ICCBased
     Name: Im8
   Fonts: 
    Type0: 
     Font: 
      BaseFont: EFGGIF+OpenSans-Semibold
      Encoding: Identity-H
      ToUnicode: true
     Font: 
      BaseFont: GODWOX+ArialUnicodeMS-Identity-H
      Encoding: Identity-H
      ToUnicode: true
     Font: 
      BaseFont: EFGGIE+OpenSans
      Encoding: Identity-H
      ToUnicode: true
    Type1: 
     Font: 
      BaseFont: TeX_CM_Maths_Symbols
      FirstChar: 1
      LastChar: 138
      FontDescriptor: 
       FontName: TeX_CM_Maths_Symbols
       Flags: Symbolic
       FontBBox: -50, -180, 1000, 720
       FontFile: true
      ToUnicode: true
     Font: 
      BaseFont: CEVEYN+MyriadPro-BoldIt
      FontSubset: true
      FirstChar: 1
      LastChar: 38
      FontDescriptor: 
       FontName: MyriadPro-BoldIt
       Flags: Nonsymbolic, Italic, ForceBold
       FontBBox: -201, -250, 1225, 987
       FontFile3: true
      EncodingDictionary: 
       BaseEncoding: WinAnsiEncoding
       Differences: true
      ToUnicode: true
     Font: 
      BaseFont: CUNFJO+MyriadPro-Regular
      FontSubset: true
      FirstChar: 1
      LastChar: 99
      FontDescriptor: 
       FontName: MyriadPro-Regular
       Flags: Nonsymbolic
       FontBBox: -157, -250, 1126, 952
       FontFile3: true
      EncodingDictionary: 
       BaseEncoding: WinAnsiEncoding
       Differences: true
      ToUnicode: true
     Font: 
      BaseFont: NITMMP+MyriadPro-SemiboldSemiCn
      FontSubset: true
      FirstChar: 1
      LastChar: 14
      FontDescriptor: 
       FontName: MyriadPro-SemiboldSemiCn
       Flags: Nonsymbolic
       FontBBox: -131, -250, 1115, 886
       FontFile3: true
      EncodingDictionary: 
       BaseEncoding: WinAnsiEncoding
       Differences: true
      ToUnicode: true
     Font: 
      BaseFont: XJHPEG+MyriadPro-Semibold
      FontSubset: true
      FirstChar: 1
      LastChar: 24
      FontDescriptor: 
       FontName: MyriadPro-Semibold
       Flags: Nonsymbolic
       FontBBox: -161, -250, 1198, 972
       FontFile3: true
      EncodingDictionary: 
       BaseEncoding: WinAnsiEncoding
       Differences: true
      ToUnicode: true
     Font: 
      BaseFont: NRPBKI+MyriadPro-It
      FontSubset: true
      FirstChar: 1
      LastChar: 12
      FontDescriptor: 
       FontName: MyriadPro-It
       Flags: Nonsymbolic, Italic
       FontBBox: -185, -250, 1090, 953
       FontFile3: true
      EncodingDictionary: 
       BaseEncoding: WinAnsiEncoding
       Differences: true
      ToUnicode: true
     Font: 
      BaseFont: IEFJDD+MyriadPro-SemiCnIt
      FontSubset: true
      FirstChar: 1
      LastChar: 34
      FontDescriptor: 
       FontName: MyriadPro-SemiCnIt
       Flags: Nonsymbolic, Italic
       FontBBox: -151, -250, 1036, 870
       FontFile3: true
      EncodingDictionary: 
       BaseEncoding: WinAnsiEncoding
       Differences: true
      ToUnicode: true
     Font: 
      BaseFont: PECCOO+MyriadPro-SemiCn
      FontSubset: true
      FirstChar: 1
      LastChar: 85
      FontDescriptor: 
       FontName: MyriadPro-SemiCn
       Flags: Nonsymbolic
       FontBBox: -128, -250, 1059, 876
       FontFile3: true
      EncodingDictionary: 
       BaseEncoding: WinAnsiEncoding
       Differences: true
      ToUnicode: true
     Font: 
      BaseFont: NKZSQL+MyriadPro-Black
      FontSubset: true
      FirstChar: 1
      LastChar: 16
      FontDescriptor: 
       FontName: MyriadPro-Black
       Flags: Nonsymbolic, ForceBold
       FontBBox: -166, -251, 1313, 1005
       FontFile3: true
      EncodingDictionary: 
       BaseEncoding: WinAnsiEncoding
       Differences: true
      ToUnicode: true
     Font: 
      BaseFont: BYNZDN+MyriadPro-BoldSemiCn
      FontSubset: true
      FirstChar: 1
      LastChar: 28
      FontDescriptor: 
       FontName: MyriadPro-BoldSemiCn
       Flags: Nonsymbolic, ForceBold
       FontBBox: -133, -250, 1161, 894
       FontFile3: true
      EncodingDictionary: 
       BaseEncoding: WinAnsiEncoding
       Differences: true
      ToUnicode: true
     Font: 
      BaseFont: YXIXTG+MyriadPro-Bold
      FontSubset: true
      FirstChar: 1
      LastChar: 45
      FontDescriptor: 
       FontName: MyriadPro-Bold
       Flags: Nonsymbolic, ForceBold
       FontBBox: -163, -250, 1256, 989
       FontFile3: true
      EncodingDictionary: 
       BaseEncoding: WinAnsiEncoding
       Differences: true
      ToUnicode: true
     Font: 
      BaseFont: TeX_CM_Maths_Extension
      FirstChar: 1
      LastChar: 150
      FontDescriptor: 
       FontName: TeX_CM_Maths_Extension
       Flags: Symbolic
       FontBBox: -50, -180, 1000, 720
       FontFile: true
      ToUnicode: true
    CIDFontType2: 
     Font: 
      BaseFont: EFGGIF+OpenSans-Semibold
      CIDSystemInfo: 
       Registry: Adobe
       Registry: UCS
       Supplement: 0
      FontDescriptor: 
       FontName: EFGGIF+OpenSans-Semibold
       Flags: FixedPitch, Nonsymbolic
       FontBBox: -583, -282, 1261, 1048
       FontFile2: true
     Font: 
      BaseFont: GODWOX+ArialUnicodeMS
      CIDSystemInfo: 
       Registry: Adobe
       Registry: Identity
       Supplement: 0
      FontDescriptor: 
       FontName: ArialUnicodeMS
       Flags: Nonsymbolic
       FontBBox: -1011, -330, 2260, 1078
       FontFile2: true
     Font: 
      BaseFont: EFGGIE+OpenSans
      CIDSystemInfo: 
       Registry: Adobe
       Registry: UCS
       Supplement: 0
      FontDescriptor: 
       FontName: EFGGIE+OpenSans
       Flags: FixedPitch, Nonsymbolic
       FontBBox: -549, -270, 1204, 1047
       FontFile2: true
   XMP: <x:xmpmeta xmlns:x="adobe:ns:meta/" x:xmptk="Adobe XMP Core 9.1-c001 79.675d0f7, 2023/06/11-19:21:16        ">
   <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#">
      <rdf:Description rdf:about=""
            xmlns:dc="http://purl.org/dc/elements/1.1/"
            xmlns:prism="http://prismstandard.org/namespaces/basic/3.0/"
            xmlns:jav="http://www.niso.org/schemas/jav/1.0/"
            xmlns:crossmark="http://crossref.org/crossmark/1.0/"
            xmlns:pdfx="http://ns.adobe.com/pdfx/1.3/"
            xmlns:xmp="http://ns.adobe.com/xap/1.0/"
            xmlns:pdf="http://ns.adobe.com/pdf/1.3/"
            xmlns:xmpMM="http://ns.adobe.com/xap/1.0/mm/">
         <dc:format>application/pdf</dc:format>
         <dc:identifier>10.1080/14737167.2022.2063842</dc:identifier>
         <dc:lang>en</dc:lang>
         <dc:title>
            <rdf:Alt>
               <rdf:li xml:lang="x-default">Assessing the value contribution of bimekizumab for the treatment of moderate-to-severe psoriasis us</rdf:li>
            </rdf:Alt>
         </dc:title>
         <dc:creator>
            <rdf:Seq>
               <rdf:li>Néboa Zozaya</rdf:li>
               <rdf:li>Fernando Abdalla</rdf:li>
               <rdf:li>Santiago Alfonso Zamora</rdf:li>
               <rdf:li>Jesús Balea Filgueiras</rdf:li>
               <rdf:li>José Manuel Carrascosa Carrillo</rdf:li>
               <rdf:li>Olga Delgado Sánchez</rdf:li>
               <rdf:li>Francisco Dolz Sinisterra</rdf:li>
               <rdf:li>Antonio García-Ruiz</rdf:li>
               <rdf:li>Pedro Herranz Pinto</rdf:li>
               <rdf:li>Antonio Manfredi</rdf:li>
               <rdf:li>José Martínez Olmos</rdf:li>
               <rdf:li>Paloma Morales de Los Ríos Luna</rdf:li>
               <rdf:li>Lluis Puig</rdf:li>
               <rdf:li>Sandra Ros</rdf:li>
               <rdf:li>Álvaro HIdalgo-Vega</rdf:li>
            </rdf:Seq>
         </dc:creator>
         <dc:publisher>
            <rdf:Bag>
               <rdf:li>Taylor &amp; Francis</rdf:li>
            </rdf:Bag>
         </dc:publisher>
         <dc:description>
            <rdf:Alt>
               <rdf:li xml:lang="x-default">Expert Review of Pharmacoeconomics &amp; Outcomes Research, 2022. doi:10.1080/14737167.2022.2063842</rdf:li>
            </rdf:Alt>
         </dc:description>
         <dc:subject>
            <rdf:Bag>
               <rdf:li>Psoriasis</rdf:li>
               <rdf:li>moderate-to-severe</rdf:li>
               <rdf:li>biologics</rdf:li>
               <rdf:li>multi-criteria decision analysis</rdf:li>
               <rdf:li>MCDA</rdf:li>
               <rdf:li>bimekizumab</rdf:li>
            </rdf:Bag>
         </dc:subject>
         <prism:aggregationType>Journal</prism:aggregationType>
         <prism:publicationName>Expert Review of Pharmacoeconomics &amp; Outcomes Research</prism:publicationName>
         <prism:copyright>© 2022 The Author(s). Published by Informa UK Limited, trading as Taylor &amp; Francis Group.</prism:copyright>
         <prism:issn>1473-7167</prism:issn>
         <prism:elssn>1744-8379</prism:elssn>
         <prism:volume>22</prism:volume>
         <prism:number>6</prism:number>
         <prism:issueName/>
         <prism:startingPage>941</prism:startingPage>
         <prism:endingPage>954</prism:endingPage>
         <prism:doi>10.1080/14737167.2022.2063842</prism:doi>
         <prism:url>https://doi.org/10.1080/14737167.2022.2063842</prism:url>
         <jav:journal_article_version>VoR</jav:journal_article_version>
         <crossmark:DOI>10.1080/14737167.2022.2063842</crossmark:DOI>
         <crossmark:MajorVersionDate>2022-04-25</crossmark:MajorVersionDate>
         <crossmark:CrossmarkDomainExclusive>True</crossmark:CrossmarkDomainExclusive>
         <crossmark:CrossMarkDomains>
            <rdf:Seq>
               <rdf:li>www.tandfonline.com</rdf:li>
            </rdf:Seq>
         </crossmark:CrossMarkDomains>
         <pdfx:doi>10.1080/14737167.2022.2063842</pdfx:doi>
         <pdfx:CrossmarkMajorVersionDate>2022-04-25</pdfx:CrossmarkMajorVersionDate>
         <pdfx:CrossmarkDomainExclusive>True</pdfx:CrossmarkDomainExclusive>
         <pdfx:CrossMarkDomains>
            <rdf:Seq>
               <rdf:li>www.tandfonline.com</rdf:li>
            </rdf:Seq>
         </pdfx:CrossMarkDomains>
         <xmp:CreateDate>2022-09-06T18:02:39+05:30</xmp:CreateDate>
         <xmp:CreatorTool>Arbortext Advanced Print Publisher 11.0.3433/W Unicode</xmp:CreatorTool>
         <xmp:ModifyDate>2024-04-18T15:47:30+02:00</xmp:ModifyDate>
         <xmp:MetadataDate>2024-04-18T15:47:30+02:00</xmp:MetadataDate>
         <pdf:Keywords>Psoriasis; moderate-to-severe; biologics; multi-criteria decision analysis; MCDA; bimekizumab</pdf:Keywords>
         <pdf:Producer>PDFlib+PDI 9.0.3p4 (C++/Win32)</pdf:Producer>
         <xmpMM:DocumentID>uuid:50869ea2-e0dd-4c0e-9420-d19f92ecb6c0</xmpMM:DocumentID>
         <xmpMM:InstanceID>uuid:81bbac38-7da6-420a-a869-2d5315d98924</xmpMM:InstanceID>
      </rdf:Description>
   </rdf:RDF>
</x:xmpmeta>
   Pages: 
    Page: 
     Label: 1
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 283, 688, 430, 696
      Annotation: 
       Subtype: Link
       Rect: 97, 364, 251, 374
      Annotation: 
       Subtype: Link
       Rect: 202, 344, 427, 354
      Annotation: 
       Subtype: Link
       Rect: 106, 241, 122, 250
      Annotation: 
       Subtype: Link
       Rect: 131, 245, 269, 254
      Annotation: 
       Subtype: Link
       Rect: 106, 160, 124, 168
      Annotation: 
       Subtype: Link
       Rect: 131, 159, 286, 168
      Annotation: 
       Subtype: Link
       Rect: 106, 69, 122, 78
      Annotation: 
       Subtype: Link
       Rect: 131, 73, 230, 82
    Page: 
     Label: 2
     Sequence: 2
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 156, 42, 477, 51
      Annotation: 
       Subtype: Link
       Rect: 106, 794, 125, 803
      Annotation: 
       Subtype: Link
       Rect: 131, 801, 232, 810
      Annotation: 
       Subtype: Link
       Rect: 106, 754, 124, 763
      Annotation: 
       Subtype: Link
       Rect: 131, 758, 292, 767
    Page: 
     Label: 1
     Sequence: 3
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 111, 641, 122, 652
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 122, 641, 126, 652
       Flags: Print
       Destination: 1
      Annotation: 
       Subtype: Link
       Rect: 126, 641, 131, 652
       Flags: Print
       Destination: 1
      Annotation: 
       Subtype: Link
       Rect: 131, 641, 131, 652
       Flags: Print
       Destination: 1
      Annotation: 
       Subtype: Link
       Rect: 216, 641, 219, 652
       Flags: Print
       Destination: 1
      Annotation: 
       Subtype: Link
       Rect: 337, 641, 340, 652
       Flags: Print
       Destination: 1
      Annotation: 
       Subtype: Link
       Rect: 442, 641, 446, 652
       Flags: Print
       Destination: 1
      Annotation: 
       Subtype: Link
       Rect: 188, 629, 199, 640
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 199, 629, 203, 640
       Flags: Print
       Destination: 1
      Annotation: 
       Subtype: Link
       Rect: 309, 629, 311, 640
       Flags: Print
       Destination: 1
      Annotation: 
       Subtype: Link
       Rect: 426, 629, 429, 640
       Flags: Print
       Destination: 1
      Annotation: 
       Subtype: Link
       Rect: 523, 629, 534, 640
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 534, 629, 538, 640
       Flags: Print
       Destination: 1
      Annotation: 
       Subtype: Link
       Rect: 138, 617, 139, 628
       Flags: Print
       Destination: 1
      Annotation: 
       Subtype: Link
       Rect: 224, 617, 227, 628
       Flags: Print
       Destination: 1
      Annotation: 
       Subtype: Link
       Rect: 325, 617, 327, 628
       Flags: Print
       Destination: 1
      Annotation: 
       Subtype: Link
       Rect: 483, 617, 486, 628
       Flags: Print
       Destination: 1
      Annotation: 
       Subtype: Link
       Rect: 535, 617, 546, 628
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 546, 617, 547, 628
       Flags: Print
       Destination: 1
      Annotation: 
       Subtype: Link
       Rect: 97, 605, 103, 616
       Flags: Print
       Destination: 1
      Annotation: 
       Subtype: Link
       Rect: 218, 605, 229, 616
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 229, 605, 233, 616
       Flags: Print
       Destination: 1
      Annotation: 
       Subtype: Link
       Rect: 233, 605, 238, 616
       Flags: Print
       Destination: 1
      Annotation: 
       Subtype: Link
       Rect: 78, 131, 83, 140
       Flags: Print
       Destination: 1
      Annotation: 
       Subtype: Link
       Rect: 506, 191, 511, 200
       Flags: Print
       Destination: 1
      Annotation: 
       Subtype: Link
       Rect: 399, 83, 403, 92
       Flags: Print
       Destination: 1
      Annotation: 
       Subtype: Link
       Rect: 223, 39, 237, 47
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 459, 744, 561, 751
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 500, 702, 561, 714
       Flags: Print
    Page: 
     Label: 2
     Sequence: 4
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 88, 695, 93, 704
       Flags: Print
       Destination: 1
      Annotation: 
       Subtype: Link
       Rect: 210, 683, 215, 692
       Flags: Print
       Destination: 1
      Annotation: 
       Subtype: Link
       Rect: 97, 659, 101, 668
       Flags: Print
       Destination: 1
      Annotation: 
       Subtype: Link
       Rect: 288, 587, 293, 596
       Flags: Print
       Destination: 1
      Annotation: 
       Subtype: Link
       Rect: 229, 563, 234, 572
       Flags: Print
       Destination: 1
      Annotation: 
       Subtype: Link
       Rect: 261, 527, 266, 536
       Flags: Print
       Destination: 1
      Annotation: 
       Subtype: Link
       Rect: 92, 431, 98, 440
       Flags: Print
       Destination: 1
      Annotation: 
       Subtype: Link
       Rect: 255, 299, 265, 308
       Flags: Print
       Destination: 1
      Annotation: 
       Subtype: Link
       Rect: 265, 299, 280, 308
       Flags: Print
       Destination: 1
      Annotation: 
       Subtype: Link
       Rect: 87, 227, 97, 236
       Flags: Print
       Destination: 1
      Annotation: 
       Subtype: Link
       Rect: 99, 227, 109, 236
       Flags: Print
       Destination: 1
      Annotation: 
       Subtype: Link
       Rect: 239, 203, 248, 212
       Flags: Print
       Destination: 1
      Annotation: 
       Subtype: Link
       Rect: 251, 203, 261, 212
       Flags: Print
       Destination: 1
      Annotation: 
       Subtype: Link
       Rect: 186, 155, 195, 164
       Flags: Print
       Destination: 1
      Annotation: 
       Subtype: Link
       Rect: 198, 155, 207, 164
       Flags: Print
       Destination: 1
      Annotation: 
       Subtype: Link
       Rect: 96, 83, 101, 92
       Flags: Print
       Destination: 1
      Annotation: 
       Subtype: Link
       Rect: 103, 83, 113, 92
       Flags: Print
       Destination: 1
      Annotation: 
       Subtype: Link
       Rect: 419, 719, 429, 728
       Flags: Print
       Destination: 1
      Annotation: 
       Subtype: Link
       Rect: 419, 491, 428, 500
       Flags: Print
       Destination: 1
      Annotation: 
       Subtype: Link
       Rect: 430, 491, 440, 500
       Flags: Print
       Destination: 1
      Annotation: 
       Subtype: Link
       Rect: 345, 59, 355, 68
       Flags: Print
       Destination: 1
      Annotation: 
       Subtype: Link
       Rect: 477, 59, 508, 68
       Flags: Print
       Destination: 1
    Page: 
     Label: 3
     Sequence: 5
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 462, 249, 472, 258
       Flags: Print
       Destination: 1
    Page: 
     Label: 4
     Sequence: 6
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 83, 516, 116, 525
       Flags: Print
       Destination: 1
      Annotation: 
       Subtype: Link
       Rect: 150, 191, 180, 200
       Flags: Print
       Destination: 1
      Annotation: 
       Subtype: Link
       Rect: 284, 83, 294, 92
       Flags: Print
       Destination: 1
      Annotation: 
       Subtype: Link
       Rect: 474, 348, 484, 357
       Flags: Print
       Destination: 1
      Annotation: 
       Subtype: Link
       Rect: 484, 348, 498, 357
       Flags: Print
       Destination: 1
    Page: 
     Label: 5
     Sequence: 7
    Page: 
     Label: 6
     Sequence: 8
    Page: 
     Label: 7
     Sequence: 9
    Page: 
     Label: 8
     Sequence: 10
    Page: 
     Label: 9
     Sequence: 11
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 216, 431, 226, 440
       Flags: Print
       Destination: 1
      Annotation: 
       Subtype: Link
       Rect: 228, 431, 238, 440
       Flags: Print
       Destination: 1
    Page: 
     Label: 10
     Sequence: 12
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 219, 515, 254, 524
       Flags: Print
       Destination: 1
      Annotation: 
       Subtype: Link
       Rect: 410, 731, 415, 740
       Flags: Print
       Destination: 1
      Annotation: 
       Subtype: Link
       Rect: 400, 707, 405, 716
       Flags: Print
       Destination: 1
      Annotation: 
       Subtype: Link
       Rect: 511, 611, 516, 620
       Flags: Print
       Destination: 1
      Annotation: 
       Subtype: Link
       Rect: 524, 587, 529, 596
       Flags: Print
       Destination: 1
      Annotation: 
       Subtype: Link
       Rect: 531, 587, 541, 596
       Flags: Print
       Destination: 1
      Annotation: 
       Subtype: Link
       Rect: 541, 587, 556, 596
       Flags: Print
       Destination: 1
      Annotation: 
       Subtype: Link
       Rect: 471, 575, 481, 584
       Flags: Print
       Destination: 1
      Annotation: 
       Subtype: Link
       Rect: 481, 575, 496, 584
       Flags: Print
       Destination: 1
      Annotation: 
       Subtype: Link
       Rect: 313, 563, 323, 572
       Flags: Print
       Destination: 1
      Annotation: 
       Subtype: Link
       Rect: 323, 563, 338, 572
       Flags: Print
       Destination: 1
      Annotation: 
       Subtype: Link
       Rect: 422, 563, 432, 572
       Flags: Print
       Destination: 1
      Annotation: 
       Subtype: Link
       Rect: 434, 563, 444, 572
       Flags: Print
       Destination: 1
      Annotation: 
       Subtype: Link
       Rect: 483, 263, 493, 272
       Flags: Print
       Destination: 1
      Annotation: 
       Subtype: Link
       Rect: 495, 263, 505, 272
       Flags: Print
       Destination: 1
      Annotation: 
       Subtype: Link
       Rect: 497, 203, 507, 212
       Flags: Print
       Destination: 1
      Annotation: 
       Subtype: Link
       Rect: 391, 143, 401, 152
       Flags: Print
       Destination: 1
      Annotation: 
       Subtype: Link
       Rect: 487, 47, 497, 56
       Flags: Print
       Destination: 1
      Annotation: 
       Subtype: Link
       Rect: 499, 47, 509, 56
       Flags: Print
       Destination: 1
    Page: 
     Label: 11
     Sequence: 13
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 89, 719, 99, 728
       Flags: Print
       Destination: 1
      Annotation: 
       Subtype: Link
       Rect: 118, 695, 128, 704
       Flags: Print
       Destination: 1
    Page: 
     Label: 12
     Sequence: 14
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 72, 605, 88, 613
       Flags: Print
       Destination: 1
      Annotation: 
       Subtype: Link
       Rect: 136, 565, 152, 573
       Flags: Print
       Destination: 1
      Annotation: 
       Subtype: Link
       Rect: 202, 525, 218, 533
       Flags: Print
       Destination: 1
      Annotation: 
       Subtype: Link
       Rect: 72, 515, 265, 523
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 98, 485, 115, 493
       Flags: Print
       Destination: 1
      Annotation: 
       Subtype: Link
       Rect: 217, 445, 233, 453
       Flags: Print
       Destination: 1
      Annotation: 
       Subtype: Link
       Rect: 274, 445, 298, 453
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 72, 435, 255, 443
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 268, 425, 284, 433
       Flags: Print
       Destination: 1
      Annotation: 
       Subtype: Link
       Rect: 159, 385, 176, 393
       Flags: Print
       Destination: 1
      Annotation: 
       Subtype: Link
       Rect: 151, 355, 167, 363
       Flags: Print
       Destination: 1
      Annotation: 
       Subtype: Link
       Rect: 72, 345, 280, 353
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 72, 335, 135, 343
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 197, 315, 213, 323
       Flags: Print
       Destination: 1
      Annotation: 
       Subtype: Link
       Rect: 272, 265, 288, 273
       Flags: Print
       Destination: 1
      Annotation: 
       Subtype: Link
       Rect: 241, 225, 257, 233
       Flags: Print
       Destination: External
      Annotation: 
       Subtype: Link
       Rect: 181, 215, 298, 223
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 72, 205, 232, 213
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 125, 165, 141, 173
       Flags: Print
       Destination: External
      Annotation: 
       Subtype: Link
       Rect: 130, 125, 146, 133
       Flags: Print
       Destination: External
      Annotation: 
       Subtype: Link
       Rect: 276, 105, 292, 113
       Flags: Print
       Destination: External
      Annotation: 
       Subtype: Link
       Rect: 272, 75, 288, 83
       Flags: Print
       Destination: 1
      Annotation: 
       Subtype: Link
       Rect: 147, 35, 163, 43
       Flags: Print
       Destination: 1
      Annotation: 
       Subtype: Link
       Rect: 388, 702, 404, 710
       Flags: Print
       Destination: 1
      Annotation: 
       Subtype: Link
       Rect: 430, 652, 446, 660
       Flags: Print
       Destination: 1
      Annotation: 
       Subtype: Link
       Rect: 535, 622, 551, 630
       Flags: Print
       Destination: 1
      Annotation: 
       Subtype: Link
       Rect: 425, 592, 441, 600
       Flags: Print
       Destination: 1
      Annotation: 
       Subtype: Link
       Rect: 389, 552, 406, 560
       Flags: Print
       Destination: 1
      Annotation: 
       Subtype: Link
       Rect: 387, 522, 403, 530
       Flags: Print
       Destination: 1
      Annotation: 
       Subtype: Link
       Rect: 464, 522, 561, 530
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 334, 512, 533, 520
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 334, 502, 399, 510
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 382, 462, 398, 470
       Flags: Print
       Destination: 1
      Annotation: 
       Subtype: Link
       Rect: 454, 412, 470, 420
       Flags: Print
       Destination: 1
      Annotation: 
       Subtype: Link
       Rect: 490, 382, 506, 390
       Flags: Print
       Destination: 1
      Annotation: 
       Subtype: Link
       Rect: 414, 372, 561, 380
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 334, 362, 381, 370
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 484, 331, 500, 339
       Flags: Print
       Destination: 1
      Annotation: 
       Subtype: Link
       Rect: 334, 321, 561, 329
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 334, 311, 412, 319
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 530, 270, 547, 278
       Flags: Print
       Destination: 1
      Annotation: 
       Subtype: Link
       Rect: 470, 240, 486, 248
       Flags: Print
       Destination: External
      Annotation: 
       Subtype: Link
       Rect: 415, 189, 432, 197
       Flags: Print
       Destination: External
      Annotation: 
       Subtype: Link
       Rect: 479, 168, 495, 176
       Flags: Print
       Destination: External
      Annotation: 
       Subtype: Link
       Rect: 441, 128, 458, 136
       Flags: Print
       Destination: External
      Annotation: 
       Subtype: Link
       Rect: 361, 77, 377, 85
       Flags: Print
       Destination: External
      Annotation: 
       Subtype: Link
       Rect: 398, 36, 414, 44
       Flags: Print
       Destination: 1
    Page: 
     Label: 13
     Sequence: 15
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 257, 692, 274, 700
       Flags: Print
       Destination: 1
      Annotation: 
       Subtype: Link
       Rect: 274, 682, 298, 690
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 72, 672, 208, 680
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 282, 622, 298, 630
       Flags: Print
       Destination: 1
      Annotation: 
       Subtype: Link
       Rect: 245, 612, 298, 620
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 72, 602, 298, 610
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 72, 592, 298, 600
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 72, 582, 270, 590
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 194, 552, 211, 560
       Flags: Print
       Destination: External
      Annotation: 
       Subtype: Link
       Rect: 262, 522, 278, 530
       Flags: Print
       Destination: External
      Annotation: 
       Subtype: Link
       Rect: 272, 482, 288, 490
       Flags: Print
       Destination: External
      Annotation: 
       Subtype: Link
       Rect: 90, 432, 106, 440
       Flags: Print
       Destination: 1
      Annotation: 
       Subtype: Link
       Rect: 334, 712, 350, 720
       Flags: Print
       Destination: External
      Annotation: 
       Subtype: Link
       Rect: 334, 672, 351, 680
       Flags: Print
       Destination: External
      Annotation: 
       Subtype: Link
       Rect: 357, 620, 373, 628
       Flags: Print
       Destination: External
      Annotation: 
       Subtype: Link
       Rect: 469, 589, 486, 597
       Flags: Print
       Destination: 1
      Annotation: 
       Subtype: Link
       Rect: 397, 579, 561, 587
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 334, 568, 381, 576
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 360, 516, 376, 524
       Flags: Print
       Destination: External
      Annotation: 
       Subtype: Link
       Rect: 506, 516, 561, 524
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 334, 505, 383, 513
       Flags: Print
      Annotation: 
       Subtype: Link
       Rect: 430, 474, 447, 482
       Flags: Print
       Destination: External
      Annotation: 
       Subtype: Link
       Rect: 459, 434, 476, 442
       Flags: Print
       Destination: External
      Annotation: 
       Subtype: Link
       Rect: 334, 424, 533, 432
       Flags: Print
  Checksum: 8c78319f
   Type: CRC32
  Checksum: 2b85f4c97f343231c84f8392a10b3c74
   Type: MD5
  Checksum: 3af2af2b5e995e5281b7da547fbfe957752be9e4
   Type: SHA-1
  Checksum: 76ce0a5d2a1f0d02dbc5ee48540647b1f18b8d9f8365f425251ea5b1df5e623d
   Type: SHA-256