1d44963354407eaa022cac777b7b611c 292089.pdf c3e447a366ad8b750b51e77e20fbd21e7de44ab4 292089.pdf cebedfe210112ddc677bf0902cb31aabba1c500a34e707e49ac0d2ccfffe2a91 292089.pdf Title: Use of sponge-assisted endoluminal vacuum therapy for the treatment of colorectal anastomotic leaks: expert panel consensus Subject: DOI: 10.1093/bjsopen/zrac123; BJS Open, 6, 5.; Abstract: Background: Anastomotic leaks represent one of the most significant complications of colorectal surgery and are the primary cause of postoperative mortality and morbidity. Sponge-assisted endoluminal vacuum therapy (EVT) has emerged as a minimally invasive technique for the management of anastomotic leaks; however, there are questions regarding patient selection due to the heterogeneous nature of anastomotic leaks and the application of sponge-assisted EVT by surgeons. Method: Seven colorectal surgical experts participated in a modified nominal group technique to establish consensus regarding key questions that arose from existing gaps in scientific evidence and the variability in clinical practice. After a bibliographic search to identify the available evidence and sequential meetings with participants, a series of recommendations and statements were formulated and agreed upon. Results: Thirty-seven recommendations and statements on the optimal use of sponge-assisted EVT were elaborated on and unanimously agreed upon by the group of experts. The statements and recommendations answer 10 key questions about the indications, benefits, and definition of the success rate of sponge-assisted EVT for the management of anastomotic leaks. Conclusion: Although further research is needed to resolve clinical and technical issues associated with sponge-assisted EVT, the recommendations and statements produced from this project summarize critical aspects to consider when using sponge-assisted EVT and to assist those involved in the management of patients with colorectal anastomotic leaks. Keywords: Author: Willem A. Bemelman Creator: Servigistics Arbortext Advanced Print Publisher 11.1.4546/W-x64 Producer: PDFlib+PDI 9.0.7p3 (C++/Win64) CreationDate: Thu Oct 20 02:41:53 2022 CEST ModDate: Thu Oct 20 17:09:44 2022 CEST Custom Metadata: yes Metadata Stream: yes Tagged: yes UserProperties: no Suspects: no Form: AcroForm JavaScript: no Pages: 7 Encrypted: no Page size: 595.276 x 782.362 pts Page rot: 0 File size: 252215 bytes Optimized: yes PDF version: 1.5 name type encoding emb sub uni object ID ------------------------------------ ----------------- ---------------- --- --- --- --------- ALCVFJ+TimesNewRomanPSMT CID TrueType Identity-H yes yes yes 772 0 OUNIPJ+CaeciliaLTStd-Italic Type 1C Custom yes yes yes 775 0 YBHNSF+CaeciliaLTStd-Roman Type 1C Custom yes yes yes 778 0 HQUSSJ+CaeciliaLTStd-Bold Type 1C Custom yes yes yes 781 0 GSDDQD+CaeciliaLTStd-Light Type 1C Custom yes yes yes 784 0 TOWVRC+CaeciliaLTStd-LightItalic Type 1C Custom yes yes yes 787 0 AAMEAM+CaeciliaLTStd-Heavy Type 1C Custom yes yes yes 790 0 FADYNR+CaeciliaLTStd-BoldItalic Type 1C Custom yes yes yes 131 0 Jhove (Rel. 1.28.0, 2023-05-18) Date: 2024-05-17 02:37:17 CEST RepresentationInformation: 292089.pdf ReportingModule: PDF-hul, Rel. 1.12.4 (2023-03-16) LastModified: 2024-05-16 12:51:54 CEST Size: 252215 Format: PDF Version: 1.5 Status: Well-Formed, but not valid SignatureMatches: PDF-hul ErrorMessage: Invalid indirect destination - referenced object 'bib' cannot be found ID: PDF-HUL-149 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'bib' cannot be found ID: PDF-HUL-122 Offset: 241776 MIMEtype: application/pdf Profile: Linearized PDF, Tagged PDF PDFMetadata: Objects: 0 FreeObjects: 1 IncrementalUpdates: 0 DocumentCatalog: ViewerPreferences: HideToolbar: false HideMenubar: false HideWindowUI: false FitWindow: false CenterWindow: false DisplayDocTitle: true NonFullScreenPageMode: UseNone Direction: L2R ViewArea: CropBox ViewClip: CropBox PrintArea: CropBox PageClip: CropBox PageLayout: OneColumn PageMode: UseOutlines Language: en Outlines: Item: Title: Use of sponge-assisted endoluminal vacuum therapy for the treatment of colorectal anastomotic leaks: expert panel consensus Destination: head1 Children: Item: Title: Introduction Destination: seczrac123-s0 Item: Title: Methods Destination: seczrac123-s1 Children: Item: Title: The expert group Destination: seczrac123-s1.1 Item: Title: Workflow Destination: seczrac123-s1.2 Item: Title: Results Destination: seczrac123-s2 Children: Item: Title: When to use sponge-assisted endoluminal vacuum therapy Destination: seczrac123-s2.1 Item: Title: When to end treatment with sponge-assisted EVT Destination: seczrac123-s2.2 Item: Title: Benefits of sponge-assisted EVT Destination: seczrac123-s2.3 Item: Title: The success rate of sponge-assisted EVT Destination: seczrac123-s2.4 Item: Title: Discussion Destination: seczrac123-s3 Item: Title: Funding Destination: seczrac123-s4 Item: Title: Acknowledgements Destination: acknow Item: Title: Disclosure Destination: seczrac123-s5 Item: Title: Supplementary material Destination: seczrac123-s6 Item: Title: Data availability Destination: seczrac123-s7 Item: Title: References Destination: reflist Filters: FilterPipeline: FlateDecode FilterPipeline: DCTDecode Images: Image: NisoImageMetadata: FormatName: image/jpg CompressionScheme: JPEG ImageWidth: 1166 ImageHeight: 563 ColorSpace: RGB BitsPerSample: 8 BitsPerSampleUnit: integer Fonts: Type0: Font: BaseFont: ALCVFJ+TimesNewRomanPSMT Encoding: Identity-H ToUnicode: true Type1: Font: BaseFont: GSDDQD+CaeciliaLTStd-Light FontSubset: true FirstChar: 1 LastChar: 88 FontDescriptor: FontName: GSDDQD+CaeciliaLTStd-Light Flags: Nonsymbolic FontBBox: -164, -266, 1130, 908 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true ToUnicode: true Font: BaseFont: TOWVRC+CaeciliaLTStd-LightItalic FontSubset: true FirstChar: 1 LastChar: 55 FontDescriptor: FontName: TOWVRC+CaeciliaLTStd-LightItalic Flags: Nonsymbolic, Italic FontBBox: -166, -267, 1033, 909 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true ToUnicode: true Font: BaseFont: FADYNR+CaeciliaLTStd-BoldItalic FontSubset: true FirstChar: 1 LastChar: 6 FontDescriptor: FontName: FADYNR+CaeciliaLTStd-BoldItalic Flags: Nonsymbolic, Italic, ForceBold FontBBox: -169, -273, 1082, 932 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true ToUnicode: true Font: BaseFont: AAMEAM+CaeciliaLTStd-Heavy FontSubset: true FirstChar: 1 LastChar: 42 FontDescriptor: FontName: AAMEAM+CaeciliaLTStd-Heavy Flags: Nonsymbolic, ForceBold FontBBox: -170, -277, 1146, 970 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true ToUnicode: true Font: BaseFont: OUNIPJ+CaeciliaLTStd-Italic FontSubset: true FirstChar: 1 LastChar: 13 FontDescriptor: FontName: OUNIPJ+CaeciliaLTStd-Italic Flags: Nonsymbolic, Italic FontBBox: -166, -270, 1053, 915 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true ToUnicode: true Font: BaseFont: YBHNSF+CaeciliaLTStd-Roman FontSubset: true FirstChar: 1 LastChar: 67 FontDescriptor: FontName: YBHNSF+CaeciliaLTStd-Roman Flags: Nonsymbolic FontBBox: -167, -270, 1136, 926 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true ToUnicode: true Font: BaseFont: HQUSSJ+CaeciliaLTStd-Bold FontSubset: true FirstChar: 1 LastChar: 61 FontDescriptor: FontName: HQUSSJ+CaeciliaLTStd-Bold Flags: Nonsymbolic, ForceBold FontBBox: -166, -273, 1141, 938 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true ToUnicode: true CIDFontType2: Font: BaseFont: ALCVFJ+TimesNewRomanPSMT CIDSystemInfo: Registry: Adobe Registry: Identity Supplement: 0 FontDescriptor: FontName: ALCVFJ+TimesNewRomanPSMT Flags: Nonsymbolic FontBBox: -568, -307, 2046, 1040 FontFile2: true XMP: uuid:53cd0a33-8387-4d0a-b853-79f8bc24bdb2 uuid:63C7A885-F99F-07B6-E807-BEB960FED73E True PDFlib+PDI 9.0.7p3 (C++/Win64) application/pdf 10.1093/bjsopen/zrac123 en Oxford University Press Use of sponge-assisted endoluminal vacuum therapy for the treatment of colorectal anastomotic leaks: expert panel consensus Willem A. Bemelman Alberto Arezzo Tomasz Banasiewicz Richard Brady Eloy Espín-Basany Omar Faiz Rosa M. Jimenez-Rodriguez DOI: 10.1093/bjsopen/zrac123; BJS Open, 6, 5.; Abstract: Background: Anastomotic leaks represent one of the most significant complications of colorectal surgery and are the primary cause of postoperative mortality and morbidity. Sponge-assisted endoluminal vacuum therapy (EVT) has emerged as a minimally invasive technique for the management of anastomotic leaks; however, there are questions regarding patient selection due to the heterogeneous nature of anastomotic leaks and the application of sponge-assisted EVT by surgeons. Method: Seven colorectal surgical experts participated in a modified nominal group technique to establish consensus regarding key questions that arose from existing gaps in scientific evidence and the variability in clinical practice. After a bibliographic search to identify the available evidence and sequential meetings with participants, a series of recommendations and statements were formulated and agreed upon. Results: Thirty-seven recommendations and statements on the optimal use of sponge-assisted EVT were elaborated on and unanimously agreed upon by the group of experts. The statements and recommendations answer 10 key questions about the indications, benefits, and definition of the success rate of sponge-assisted EVT for the management of anastomotic leaks. Conclusion: Although further research is needed to resolve clinical and technical issues associated with sponge-assisted EVT, the recommendations and statements produced from this project summarize critical aspects to consider when using sponge-assisted EVT and to assist those involved in the management of patients with colorectal anastomotic leaks. © The Author(s) 2022. Published by Oxford University Press on behalf of BJS Society Ltd. Journal BJS Open © The Author(s) 2022. 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