d680c839fd9444b410570846cdfa07cc 292661.pdf b22fb41136e6d159d2e0caa004aec6a013ed357a 292661.pdf cdf4d2a6e8a2348c696fed2a5e6b1c84d487c08965fc927f683f61cecbd59431 292661.pdf Title: In silico Identification of Immune Cell-Types and Pathways Involved in Chronic Spontaneous Urticaria Subject: Background: The immunopathogenesis of chronic spontaneous urticaria (CSU) is poorly understood, but recent research suggests that patients can be divided into autoallergic and autoimmune subtypes. Keywords: chronic spontaneous urticaria, chronic urticaria, autoimmunity, autoallergy, chronic idiopathic urticaria, pathogenesis, Th2, Th17 Author: Connor Prosty and Ivan V. Litvinov Creator: LaTeX with hyperref package Producer: pdfTeX-1.40.16 CreationDate: Thu Jul 7 03:45:49 2022 CEST ModDate: Thu Jul 7 04:31:58 2022 CEST Custom Metadata: yes Metadata Stream: yes Tagged: no UserProperties: no Suspects: no Form: none JavaScript: no Pages: 14 Encrypted: no Page size: 595.276 x 779.528 pts Page rot: 0 File size: 10633032 bytes Optimized: no PDF version: 1.5 name type encoding emb sub uni object ID ------------------------------------ ----------------- ---------------- --- --- --- --------- VJELVY+MinionPro-Regular Type 1 Custom yes yes no 24 0 IDMKMO+HelveticaNeueLTStd-Bd Type 1 Custom yes yes no 25 0 EPHIYT+HelveticaNeueLTStd-Lt Type 1 Custom yes yes no 26 0 WIQCLD+HelveticaNeueLTStd-BdIt Type 1 Custom yes yes no 31 0 LAJHIN+HelveticaNeueLTStd-LtIt Type 1 Custom yes yes no 32 0 TIEAWB+HelveticaNeueLTStd-MdIt Type 1 Custom yes yes no 33 0 PAARCL+RBLMI Type 1 Builtin yes yes no 34 0 BFDZID+MTSYN Type 1 Builtin yes yes no 35 0 OHERRI+MTGU Type 1 Builtin yes yes no 94 0 JFMHOG+MinionPro-It Type 1 Custom yes yes no 95 0 PBFVCW+MinionPro-Bold Type 1 Custom yes yes no 96 0 Jhove (Rel. 1.28.0, 2023-05-18) Date: 2024-05-31 02:36:50 CEST RepresentationInformation: 292661.pdf ReportingModule: PDF-hul, Rel. 1.12.4 (2023-03-16) LastModified: 2024-05-30 16:18:10 CEST Size: 10633032 Format: PDF Version: 1.5 Status: Well-Formed and valid SignatureMatches: PDF-hul MIMEtype: application/pdf PDFMetadata: Objects: 786 FreeObjects: 3 IncrementalUpdates: 1 DocumentCatalog: PageLayout: SinglePage PageMode: UseOutlines Outlines: Item: Title: In silico Identification of Immune Cell-Types and Pathways Involved in Chronic Spontaneous Urticaria Children: Item: Title: Introduction Item: Title: Materials and Methods Children: Item: Title: Data Acquisition Item: Title: Pathway Analysis Item: Title: Unsupervised Clustering and Violin Plots Item: Title: Cell-Type Estimation Item: Title: Statistical Analyses Item: Title: Results Children: Item: Title: Lesional Versus Healthy Control Skin: Differentially Expressed Genes and Unsupervised Hierarchal Clustering Item: Title: Lesional Versus Healthy Control Skin: Pathways Item: Title: Lesional Versus Non-lesional Skin: Differentially Expressed Genes and Unsupervised Hierarchal Clustering Item: Title: Lesional Versus Non-lesional Skin: Pathways Item: Title: Chronic Spontaneous Urticaria Versus Healthy Control Blood: Pathways and Differentially Expressed Genes Item: Title: Lesional Versus Healthy Control Skin: Cell-Type Enrichment Item: Title: Lesional Versus Non-lesional Skin: Cell-Type Enrichment Item: Title: Chronic Spontaneous Urticaria Versus Healthy Control Blood: Cell-Type Enrichment Item: Title: Individual Dataset Analyses: Cell-Type Enrichment Item: Title: Discussion Item: Title: Conclusion Item: Title: Data Availability Statement Item: Title: Author Contributions Item: Title: Funding Item: Title: Acknowledgments Item: Title: Supplementary Material Item: Title: References Info: Title: In silico Identification of Immune Cell-Types and Pathways Involved in Chronic Spontaneous Urticaria Author: Connor Prosty and Ivan V. Litvinov Subject: Background: The immunopathogenesis of chronic spontaneous urticaria (CSU) is poorly understood, but recent research suggests that patients can be divided into autoallergic and autoimmune subtypes. 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Connor Prosty and Ivan V. 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