7736e483ddb2de5f7103a1ed467ebb96 fpubh-10-1038138.pdf e17bbc6b50a133aba1f07dbc0e0fd8f6ae0d77b6 fpubh-10-1038138.pdf 87ba1270c3acd55bc5645466a03278967e56bec89910d6fe5dd05aab8b6afeb5 fpubh-10-1038138.pdf Title: Improving Initial Medication Adherence to cardiovascular disease and diabetes treatments in primary care: Pilot trial of a complex intervention Subject: Introduction: The Initial Medication Adherence (IMA) intervention is a multidisciplinary and shared decision-making intervention to improve initial medication adherence addressed to patients in need of new treatments for cardiovascular diseases and diabetes in primary care (PC). Keywords: primary care, complex intervention, shared decision-making (SDM), medication adherence, pilot, feasibility study Author: Carmen Corral-Partearroyo Creator: LaTeX with hyperref package + hypdvips Producer: dvips + MiKTeX GPL Ghostscript 9.0 CreationDate: Tue Dec 6 05:16:11 2022 CET ModDate: Tue Dec 6 06:49:11 2022 CET Custom Metadata: no Metadata Stream: yes Tagged: no UserProperties: no Suspects: no Form: AcroForm JavaScript: no Pages: 16 Encrypted: no Page size: 595.26 x 842.116 pts (A4) Page rot: 0 File size: 1527632 bytes Optimized: no PDF version: 1.6 name type encoding emb sub uni object ID ------------------------------------ ----------------- ---------------- --- --- --- --------- EHOSJI+MuseoSans-700 Type 1C Custom yes yes yes 54 0 KXRDBW+MuseoSans-300 Type 1C Custom yes yes yes 57 0 MRBMFP+MuseoSans-300Italic Type 1C WinAnsi yes yes no 69 0 GVBYDT+MinionPro-Regular Type 1C Custom yes yes no 72 0 CNGKJJ+MuseoSans-500 Type 1C Custom yes yes yes 79 0 IAAFVL+RMTMI Type 1C WinAnsi yes yes no 115 0 UNIDRP+MinionPro-It Type 1C Custom yes yes no 134 0 VHXNJS+MinionPro-Bold Type 1C WinAnsi yes yes no 189 0 Times-Roman Type 1 Standard no no no 191 0 WJSFFF+MinionPro-BoldIt Type 1C WinAnsi yes yes no 192 0 UADLTO+MTSYB Type 1C Custom yes yes no 195 0 WBEMYH+MTSY Type 1C Custom yes yes no 199 0 EQBLZY+MuseoSans-700Italic Type 1C WinAnsi yes yes no 217 0 Jhove (Rel. 1.28.0, 2023-05-18) Date: 2025-05-27 03:05:33 CEST RepresentationInformation: fpubh-10-1038138.pdf ReportingModule: PDF-hul, Rel. 1.12.4 (2023-03-16) LastModified: 2025-05-26 18:59:57 CEST Size: 1527632 Format: PDF Version: 1.6 Status: Well-Formed and valid SignatureMatches: PDF-hul MIMEtype: application/pdf PDFMetadata: Objects: 398 FreeObjects: 34 IncrementalUpdates: 0 DocumentCatalog: ViewerPreferences: HideToolbar: false HideMenubar: false HideWindowUI: false FitWindow: true CenterWindow: false DisplayDocTitle: false NonFullScreenPageMode: UseNone Direction: L2R ViewArea: CropBox ViewClip: CropBox PrintArea: CropBox PageClip: CropBox PageLayout: SinglePage PageMode: UseOutlines Language: en Outlines: Item: Title: Improving Initial Medication Adherence to cardiovascular disease and diabetes treatments in primary care: Pilot trial of a complex intervention Destination: ariclecounter.1 Children: Item: Title: Introduction Destination: section*.2 Item: Title: Materials and methods Destination: section*.3 Children: Item: Title: Study design Destination: section*.4 Item: Title: Setting Destination: section*.5 Item: Title: Pilot study Destination: section*.6 Children: Item: Title: Participants and group assignment Destination: section*.7 Item: Title: Description of intervention Destination: section*.8 Item: Title: Availability and quality of RWD for the trial (aim 1) Destination: section*.9 Children: Item: Title: Trial outcomes and data collection Destination: section*.10 Item: Title: Analysis Destination: section*.11 Item: Title: Feasibility and acceptability of the IMA intervention (aim 2) Destination: section*.12 Children: Item: Title: Quantitative data collection and analysis Destination: section*.13 Item: Title: Qualitative data collection and analysis Destination: section*.14 Item: Title: Redesign of the IMA intervention tools (aim 3) Destination: section*.15 Children: Item: Title: Data collection and analysis Destination: section*.16 Item: Title: Results Destination: section*.17 Children: Item: Title: Participants Destination: section*.18 Item: Title: Availability and quality of RWD for the trial (aim 1) Destination: section*.19 Children: Item: Title: Initiation and implementation Destination: section*.20 Item: Title: Feasibility and acceptability of the IMA intervention (aim 2) Destination: section*.21 Children: Item: Title: Professional recruitment and retention rates Destination: section*.22 Item: Title: Context and implementation of the IMA intervention Destination: section*.23 Children: Item: Title: Training for professionals Destination: section*.24 Item: Title: Decision aids Destination: section*.25 Item: Title: Shared decision-making Destination: section*.26 Item: Title: Other professional information support Destination: section*.27 Item: Title: Professionals' and patients' experiences and perceptions in terms of feasibility and acceptability: Key themes Destination: section*.28 Children: Item: Title: Perceived effect of the IMA intervention by professionals Destination: section*.29 Item: Title: Relationship and trust between the professional and patient Destination: section*.30 Item: Title: Motivation for professionals to adapt their clinical practice Destination: section*.31 Item: Title: Redesign of the IMA intervention tools (aim 3) Destination: section*.32 Item: Title: Discussion Destination: section*.33 Item: Title: Data availability statement Destination: section*.34 Item: Title: Ethics statement Destination: section*.35 Item: Title: Author contributions Destination: section*.36 Item: Title: Funding Destination: section*.37 Item: Title: Acknowledgments Destination: section*.38 Item: Title: Conflict of interest Destination: section*.39 Item: Title: Publisher's note Destination: section*.40 Item: Title: Supplementary material Destination: section*.41 Item: Title: References Destination: section*.42 Info: Title: Improving Initial Medication Adherence to cardiovascular disease and diabetes treatments in primary care: Pilot trial of a complex intervention Author: Carmen Corral-Partearroyo Subject: Introduction: The Initial Medication Adherence (IMA) intervention is a multidisciplinary and shared decision-making intervention to improve initial medication adherence addressed to patients in need of new treatments for cardiovascular diseases and diabetes in primary care (PC). Keywords: primary care, complex intervention, shared decision-making (SDM), medication adherence, pilot, feasibility study Creator: LaTeX with hyperref package + hypdvips Producer: dvips + MiKTeX GPL Ghostscript 9.0 CreationDate: Tue Dec 06 05:46:11 CET 2022 ModDate: Tue Dec 06 07:19:11 CET 2022 ID: 0x6f2d22cacda4aa4a66c08b3abfdeb9f5, 0x727e155fad018b4198e153172ce1657a Filters: FilterPipeline: FlateDecode FilterPipeline: DCTDecode Images: Image: NisoImageMetadata: FormatName: image/png ImageWidth: 32 ImageHeight: 128 ColorSpace: RGB BitsPerSample: 8 BitsPerSampleUnit: integer Filter: FlateDecode Image: NisoImageMetadata: FormatName: image/jpg CompressionScheme: JPEG ImageWidth: 1890 ImageHeight: 636 ColorSpace: RGB BitsPerSample: 8 BitsPerSampleUnit: integer Interpolate: true Image: NisoImageMetadata: FormatName: image/jpg CompressionScheme: JPEG ImageWidth: 1417 ImageHeight: 1845 ColorSpace: RGB BitsPerSample: 8 BitsPerSampleUnit: integer Interpolate: true Image: NisoImageMetadata: FormatName: image/jpg CompressionScheme: JPEG ImageWidth: 1772 ImageHeight: 2318 ColorSpace: RGB BitsPerSample: 8 BitsPerSampleUnit: integer Interpolate: true Fonts: Type1: Font: BaseFont: WJSFFF+MinionPro-BoldIt FontSubset: true FirstChar: 78 LastChar: 78 FontDescriptor: FontName: WJSFFF+MinionPro-BoldIt Flags: Nonsymbolic, AllCap FontBBox: -6, -10, 765, 700 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: UADLTO+MTSYB FontSubset: true FirstChar: 68 LastChar: 68 FontDescriptor: FontName: UADLTO+MTSYB Flags: Symbolic, AllCap FontBBox: 0, 0, 724, 387 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true Font: BaseFont: MRBMFP+MuseoSans-300Italic FontSubset: true FirstChar: 46 LastChar: 117 FontDescriptor: FontName: MRBMFP+MuseoSans-300Italic Flags: Nonsymbolic, SmallCap FontBBox: -53, -12, 727, 703 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: UNIDRP+MinionPro-It FontSubset: true FirstChar: 2 LastChar: 243 FontDescriptor: FontName: UNIDRP+MinionPro-It Flags: Symbolic FontBBox: -142, -257, 1003, 811 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true Font: BaseFont: WBEMYH+MTSY FontSubset: true FirstChar: 1 LastChar: 24 FontDescriptor: FontName: WBEMYH+MTSY Flags: Symbolic FontBBox: 0, 0, 724, 423 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true Font: BaseFont: GVBYDT+MinionPro-Regular FontSubset: true FirstChar: 2 LastChar: 252 FontDescriptor: FontName: GVBYDT+MinionPro-Regular Flags: Symbolic FontBBox: -26, -257, 956, 713 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true Font: BaseFont: CNGKJJ+MuseoSans-500 FontSubset: true FirstChar: 0 LastChar: 241 FontDescriptor: FontName: CNGKJJ+MuseoSans-500 Flags: Symbolic FontBBox: 2, -210, 916, 744 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true ToUnicode: true Font: BaseFont: IAAFVL+RMTMI FontSubset: true FirstChar: 62 LastChar: 62 FontDescriptor: FontName: IAAFVL+RMTMI Flags: Nonsymbolic, AllCap FontBBox: 0, 0, 683, 455 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: EHOSJI+MuseoSans-700 FontSubset: true FirstChar: 40 LastChar: 121 FontDescriptor: FontName: EHOSJI+MuseoSans-700 Flags: Symbolic FontBBox: -8, -210, 941, 741 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true ToUnicode: true Font: BaseFont: KXRDBW+MuseoSans-300 FontSubset: true FirstChar: 0 LastChar: 250 FontDescriptor: FontName: KXRDBW+MuseoSans-300 Flags: Symbolic FontBBox: -55, -210, 890, 742 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true ToUnicode: true Font: BaseFont: EQBLZY+MuseoSans-700Italic FontSubset: true FirstChar: 78 LastChar: 115 FontDescriptor: FontName: EQBLZY+MuseoSans-700Italic Flags: Nonsymbolic, SmallCap FontBBox: -53, -12, 743, 710 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: VHXNJS+MinionPro-Bold FontSubset: true FirstChar: 37 LastChar: 121 FontDescriptor: FontName: VHXNJS+MinionPro-Bold Flags: Nonsymbolic FontBBox: -8, -245, 969, 714 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: Times-Roman XMP: 2022-12-06T09:46:11+05:30 LaTeX with hyperref package + hypdvips 2022-12-06T11:19:11+05:30 2022-12-06T11:19:11+05:30 application/pdf Introduction: The Initial Medication Adherence (IMA) intervention is a multidisciplinary and shared decision-making intervention to improve initial medication adherence addressed to patients in need of new treatments for cardiovascular diseases and diabetes in primary care (PC). Carmen Corral-Partearroyo Alba Sánchez-Viñas Montserrat Gil-Girbau Marı́a Teresa Peñarrubia-Marı́a Ignacio Aznar-Lou Antoni Serrano-Blanco Cristina Carbonell-Duacastella Carmen Gallardo-González Maria del Carmen Olmos-Palenzuela Maria Rubio-Valera Improving Initial Medication Adherence to cardiovascular disease and diabetes treatments in primary care: Pilot trial of a complex intervention primary care complex intervention shared decision-making (SDM) medication adherence pilot feasibility study primary care, complex intervention, shared decision-making (SDM), medication adherence, pilot, feasibility study dvips + MiKTeX GPL Ghostscript 9.0 uuid:cbc736a1-d256-4483-b1af-7e7c9e0bc680 uuid:8be826a7-7964-4fe7-bf79-089037d82af4 Pages: Page: Label: 1 Annotations: Annotation: Subtype: Link Rect: 55, 781, 243, 798 Annotation: Subtype: Link Rect: 447, 792, 487, 800 Annotation: Subtype: Link Rect: 464, 783, 473, 791 Annotation: Subtype: Link Rect: 473, 784, 509, 791 Annotation: Subtype: Link Rect: 509, 783, 527, 791 Annotation: Subtype: Link Rect: 444, 774, 539, 783 Annotation: Subtype: Link Rect: 55, 690, 131, 707 Annotation: Subtype: Link Rect: 55, 532, 116, 540 Annotation: Subtype: Link Rect: 69, 312, 165, 320 Annotation: Subtype: Link Rect: 108, 218, 136, 226 Annotation: Subtype: Link Rect: 136, 218, 172, 226 Annotation: Subtype: Link Rect: 55, 209, 91, 217 Annotation: Subtype: Link Rect: 91, 209, 117, 217 Annotation: Subtype: Link Rect: 117, 209, 143, 217 Annotation: Subtype: Link Rect: 221, 586, 539, 707 Annotation: Subtype: Link Rect: 55, 43, 137, 50 Annotation: Subtype: Link Rect: 491, 41, 539, 50 Page: Label: 2 Sequence: 2 Annotations: Annotation: Subtype: Link Rect: 442, 791, 539, 799 Annotation: Subtype: Link Rect: 329, 547, 399, 557 Annotation: Subtype: Link Rect: 58, 379, 65, 392 Destination: External Annotation: Subtype: Link Rect: 67, 379, 74, 392 Destination: External Annotation: Subtype: Link Rect: 100, 342, 106, 354 Destination: External Annotation: Subtype: Link Rect: 111, 342, 117, 354 Destination: External Annotation: Subtype: Link Rect: 120, 342, 126, 354 Destination: External Annotation: Subtype: Link Rect: 216, 329, 222, 342 Destination: External Annotation: Subtype: Link Rect: 158, 292, 169, 305 Destination: External Annotation: Subtype: Link Rect: 171, 292, 182, 305 Destination: External Annotation: Subtype: Link Rect: 157, 255, 167, 267 Destination: External Annotation: Subtype: Link Rect: 170, 255, 181, 267 Destination: External Annotation: Subtype: Link Rect: 127, 217, 138, 230 Destination: External Annotation: Subtype: Link Rect: 142, 217, 153, 230 Destination: External Annotation: Subtype: Link Rect: 464, 405, 475, 417 Destination: External Annotation: Subtype: Link Rect: 479, 343, 490, 355 Destination: External Annotation: Subtype: Link Rect: 493, 343, 503, 355 Destination: External Annotation: Subtype: Link Rect: 447, 293, 458, 305 Destination: External Annotation: Subtype: Link Rect: 461, 293, 472, 305 Destination: External Annotation: Subtype: Link Rect: 377, 255, 387, 268 Destination: External Annotation: Subtype: Link Rect: 390, 255, 401, 268 Destination: External Annotation: Subtype: Link Rect: 440, 231, 451, 243 Destination: External Annotation: Subtype: Link Rect: 453, 231, 464, 243 Destination: External Annotation: Subtype: Link Rect: 494, 143, 504, 156 Destination: External Annotation: Subtype: Link Rect: 507, 143, 518, 156 Destination: External Annotation: Subtype: Link Rect: 55, 42, 137, 49 Annotation: Subtype: Link Rect: 491, 40, 539, 49 Page: Label: 3 Sequence: 3 Annotations: Annotation: Subtype: Link Rect: 442, 791, 539, 799 Annotation: Subtype: Link Rect: 195, 522, 206, 534 Destination: External Annotation: Subtype: Link Rect: 69, 507, 101, 517 Destination: External Annotation: Subtype: Link Rect: 229, 358, 239, 370 Destination: External Annotation: Subtype: Link Rect: 215, 271, 225, 283 Destination: External Annotation: Subtype: Link Rect: 410, 630, 420, 642 Destination: External Annotation: Subtype: Link Rect: 338, 468, 349, 480 Destination: External Annotation: Subtype: Link Rect: 398, 319, 409, 331 Destination: External Annotation: Subtype: Link Rect: 412, 319, 423, 331 Destination: External Annotation: Subtype: Link Rect: 55, 43, 137, 50 Annotation: Subtype: Link Rect: 491, 41, 539, 50 Page: Label: 4 Sequence: 4 Annotations: Annotation: Subtype: Link Rect: 442, 791, 539, 799 Annotation: Subtype: Link Rect: 151, 439, 161, 452 Destination: External Annotation: Subtype: Link Rect: 203, 365, 213, 377 Destination: External Annotation: Subtype: Link Rect: 135, 315, 146, 327 Destination: External Annotation: Subtype: Link Rect: 251, 228, 262, 240 Destination: External Annotation: Subtype: Link Rect: 349, 278, 360, 290 Destination: External Annotation: Subtype: Link Rect: 362, 278, 373, 290 Destination: External Annotation: Subtype: Link Rect: 55, 43, 137, 50 Annotation: Subtype: Link Rect: 491, 41, 539, 50 Page: Label: 5 Sequence: 5 Annotations: Annotation: Subtype: Link Rect: 204, 382, 215, 394 Destination: External Annotation: Subtype: Link Rect: 271, 119, 282, 132 Destination: External Annotation: Subtype: Link Rect: 387, 642, 397, 655 Destination: External Annotation: Subtype: Link Rect: 494, 391, 526, 401 Destination: External Annotation: Subtype: Link Rect: 321, 368, 352, 377 Destination: External Annotation: Subtype: Link Rect: 356, 368, 362, 376 Destination: External Annotation: Subtype: Link Rect: 506, 331, 534, 340 Destination: External Annotation: Subtype: Link Rect: 457, 256, 485, 265 Destination: External Annotation: Subtype: Link Rect: 317, 92, 404, 103 Destination: External Annotation: Subtype: Link Rect: 407, 94, 413, 102 Destination: External Page: Label: 6 Sequence: 6 Annotations: Annotation: Subtype: Link Rect: 442, 791, 539, 799 Annotation: Subtype: Link Rect: 151, 271, 161, 280 Destination: External Annotation: Subtype: Link Rect: 69, 138, 97, 147 Destination: External Annotation: Subtype: Link Rect: 321, 177, 352, 186 Destination: External Annotation: Subtype: Link Rect: 356, 177, 363, 185 Destination: External Annotation: Subtype: Link Rect: 506, 127, 534, 136 Destination: External Annotation: Subtype: Link Rect: 362, 90, 389, 98 Destination: External Annotation: Subtype: Link Rect: 55, 43, 137, 50 Annotation: Subtype: Link Rect: 491, 41, 539, 50 Page: Label: 7 Sequence: 7 Annotations: Annotation: Subtype: Link Rect: 442, 791, 539, 799 Annotation: Subtype: Link Rect: 205, 588, 213, 597 Destination: External Annotation: Subtype: Link Rect: 233, 366, 241, 375 Destination: External Annotation: Subtype: Link Rect: 69, 266, 97, 275 Destination: External Annotation: Subtype: Link Rect: 439, 153, 471, 163 Destination: External Annotation: Subtype: Link Rect: 55, 43, 137, 50 Annotation: Subtype: Link Rect: 491, 41, 539, 50 Page: Label: 8 Sequence: 8 Annotations: Annotation: Subtype: Link Rect: 442, 791, 539, 799 Annotation: Subtype: Link Rect: 300, 411, 364, 419 Destination: External Annotation: Subtype: Link Rect: 55, 43, 137, 50 Annotation: Subtype: Link Rect: 491, 41, 539, 50 Page: Label: 9 Sequence: 9 Annotations: Annotation: Subtype: Link Rect: 442, 791, 539, 799 Annotation: Subtype: Link Rect: 55, 43, 137, 50 Annotation: Subtype: Link Rect: 491, 41, 539, 50 Page: Label: 10 Sequence: 10 Annotations: Annotation: Subtype: Link Rect: 442, 791, 539, 799 Annotation: Subtype: Link Rect: 361, 119, 372, 132 Destination: External Annotation: Subtype: Link Rect: 526, 94, 537, 107 Destination: External Annotation: Subtype: Link Rect: 55, 43, 137, 50 Annotation: Subtype: Link Rect: 491, 41, 539, 50 Page: Label: 11 Sequence: 11 Annotations: Annotation: Subtype: Link Rect: 442, 791, 539, 799 Annotation: Subtype: Link Rect: 55, 43, 137, 50 Annotation: Subtype: Link Rect: 491, 41, 539, 50 Page: Label: 12 Sequence: 12 Annotations: Annotation: Subtype: Link Rect: 442, 791, 539, 799 Annotation: Subtype: Link Rect: 55, 742, 66, 754 Destination: External Annotation: Subtype: Link Rect: 150, 692, 161, 705 Destination: External Annotation: Subtype: Link Rect: 99, 518, 110, 530 Destination: External Annotation: Subtype: Link Rect: 113, 518, 123, 530 Destination: External Annotation: Subtype: Link Rect: 182, 418, 192, 431 Destination: External Annotation: Subtype: Link Rect: 195, 418, 205, 431 Destination: External Annotation: Subtype: Link Rect: 207, 418, 218, 431 Destination: External Annotation: Subtype: Link Rect: 210, 319, 221, 331 Destination: External Annotation: Subtype: Link Rect: 224, 319, 235, 331 Destination: External Annotation: Subtype: Link Rect: 148, 144, 159, 157 Destination: External Annotation: Subtype: Link Rect: 164, 144, 175, 157 Destination: External Annotation: Subtype: Link Rect: 370, 730, 380, 742 Destination: External Annotation: Subtype: Link Rect: 385, 730, 396, 742 Destination: External Annotation: Subtype: Link Rect: 363, 692, 374, 705 Destination: External Annotation: Subtype: Link Rect: 372, 617, 383, 630 Destination: External Annotation: Subtype: Link Rect: 386, 617, 397, 630 Destination: External Annotation: Subtype: Link Rect: 383, 331, 393, 344 Destination: External Annotation: Subtype: Link Rect: 55, 43, 137, 50 Annotation: Subtype: Link Rect: 491, 41, 539, 50 Page: Label: 13 Sequence: 13 Annotations: Annotation: Subtype: Link Rect: 442, 791, 539, 799 Annotation: Subtype: Link Rect: 65, 92, 135, 103 Annotation: Subtype: Link Rect: 510, 617, 520, 629 Destination: External Annotation: Subtype: Link Rect: 445, 592, 456, 604 Destination: External Annotation: Subtype: Link Rect: 457, 592, 468, 604 Destination: External Annotation: Subtype: Link Rect: 55, 43, 137, 50 Annotation: Subtype: Link Rect: 491, 41, 539, 50 Page: Label: 14 Sequence: 14 Annotations: Annotation: Subtype: Link Rect: 442, 791, 539, 799 Annotation: Subtype: Link Rect: 540, 369, 306, 394 Annotation: Subtype: Link Rect: 77, 269, 174, 277 Annotation: Subtype: Link Rect: 99, 242, 162, 249 Annotation: Subtype: Link Rect: 81, 197, 155, 206 Annotation: Subtype: Link Rect: 186, 169, 273, 178 Annotation: Subtype: Link Rect: 119, 142, 195, 150 Annotation: Subtype: Link Rect: 156, 113, 252, 122 Annotation: Subtype: Link Rect: 345, 284, 427, 293 Annotation: Subtype: Link Rect: 540, 248, 306, 266 Annotation: Subtype: Link Rect: 517, 227, 539, 236 Annotation: Subtype: Link Rect: 307, 219, 539, 228 Annotation: Subtype: Link Rect: 307, 211, 351, 220 Annotation: Subtype: Link Rect: 352, 175, 447, 184 Annotation: Subtype: Link Rect: 326, 141, 422, 148 Annotation: Subtype: Link Rect: 540, 94, 306, 113 Annotation: Subtype: Link Rect: 55, 42, 137, 49 Annotation: Subtype: Link Rect: 491, 40, 539, 49 Page: Label: 15 Sequence: 15 Annotations: Annotation: Subtype: Link Rect: 442, 791, 539, 799 Annotation: Subtype: Link Rect: 103, 718, 158, 725 Annotation: Subtype: Link Rect: 107, 688, 184, 697 Annotation: Subtype: Link Rect: 85, 645, 190, 653 Annotation: Subtype: Link Rect: 147, 617, 220, 625 Annotation: Subtype: Link Rect: 103, 581, 177, 589 Annotation: Subtype: Link Rect: 99, 539, 191, 546 Annotation: Subtype: Link Rect: 99, 509, 173, 518 Annotation: Subtype: Link Rect: 187, 481, 242, 490 Annotation: Subtype: Link Rect: 105, 445, 192, 454 Annotation: Subtype: Link Rect: 156, 410, 210, 418 Annotation: Subtype: Link Rect: 99, 374, 172, 382 Annotation: Subtype: Link Rect: 119, 338, 201, 347 Annotation: Subtype: Link Rect: 77, 302, 166, 311 Annotation: Subtype: Link Rect: 102, 260, 156, 267 Annotation: Subtype: Link Rect: 192, 222, 261, 231 Annotation: Subtype: Link Rect: 187, 196, 264, 203 Annotation: Subtype: Link Rect: 201, 166, 287, 175 Annotation: Subtype: Link Rect: 55, 159, 111, 167 Annotation: Subtype: Link Rect: 119, 132, 199, 139 Annotation: Subtype: Link Rect: 348, 688, 430, 697 Annotation: Subtype: Link Rect: 448, 638, 530, 645 Annotation: Subtype: Link Rect: 354, 585, 444, 594 Annotation: Subtype: Link Rect: 389, 557, 443, 566 Annotation: Subtype: Link Rect: 361, 529, 539, 538 Annotation: Subtype: Link Rect: 307, 521, 359, 530 Annotation: Subtype: Link Rect: 396, 485, 539, 494 Annotation: Subtype: Link Rect: 307, 478, 390, 486 Annotation: Subtype: Link Rect: 334, 451, 405, 458 Annotation: Subtype: Link Rect: 421, 421, 518, 430 Annotation: Subtype: Link Rect: 446, 394, 539, 402 Annotation: Subtype: Link Rect: 409, 374, 477, 382 Annotation: Subtype: Link Rect: 541, 237, 306, 256 Annotation: Subtype: Link Rect: 540, 173, 306, 200 Annotation: Subtype: Link Rect: 483, 155, 539, 163 Annotation: Subtype: Link Rect: 307, 148, 361, 155 Annotation: Subtype: Link Rect: 368, 112, 420, 119 Annotation: Subtype: Link Rect: 55, 43, 137, 50 Annotation: Subtype: Link Rect: 491, 41, 539, 50 Page: Label: 16 Sequence: 16 Annotations: Annotation: Subtype: Link Rect: 442, 791, 539, 799 Annotation: Subtype: Link Rect: 157, 718, 200, 725 Annotation: Subtype: Link Rect: 91, 682, 179, 689 Annotation: Subtype: Link Rect: 135, 646, 215, 653 Annotation: Subtype: Link Rect: 288, 601, 54, 618 Annotation: Subtype: Link Rect: 348, 716, 421, 725 Annotation: Subtype: Link Rect: 334, 682, 405, 689 Annotation: Subtype: Link Rect: 330, 646, 403, 654 Annotation: Subtype: Link Rect: 55, 43, 137, 50 Annotation: Subtype: Link Rect: 491, 41, 539, 50 Checksum: 79ba13ce Type: CRC32 Checksum: 7736e483ddb2de5f7103a1ed467ebb96 Type: MD5 Checksum: e17bbc6b50a133aba1f07dbc0e0fd8f6ae0d77b6 Type: SHA-1 Checksum: 87ba1270c3acd55bc5645466a03278967e56bec89910d6fe5dd05aab8b6afeb5 Type: SHA-256