c5e624bba5f7a73850526cfc18d120c6  2018_CurrentBiol_Carrete_etal.pdf
186990e0af176dbc6adcaaba5af218230e37993d  2018_CurrentBiol_Carrete_etal.pdf
13cab8eafe7bcdda8a4b194acc9b5b82bac39ed2da50936e85da6fe113c4c795  2018_CurrentBiol_Carrete_etal.pdf

Title:           Patterns of Genomic Variation in the Opportunistic Pathogen Candida glabrata Suggest the Existence of Mating and a Secondary Association with Humans
Subject:         Current Biology, 28 (2018) 15-34. doi:10.1016/j.cub.2017.11.027
Author:          Laia Carreté
Creator:         Elsevier
Producer:        Acrobat Distiller 8.1.0 (Windows)
CreationDate:    Tue Jan  2 21:20:47 2018 CET
ModDate:         Wed Jan  3 05:35:47 2018 CET
Custom Metadata: yes
Metadata Stream: yes
Tagged:          no
UserProperties:  no
Suspects:        no
Form:            none
JavaScript:      no
Pages:           21
Encrypted:       no
Page size:       602.986 x 782.986 pts
Page rot:        0
File size:       3561512 bytes
Optimized:       yes
PDF version:     1.7


name                                 type              encoding         emb sub uni object ID
------------------------------------ ----------------- ---------------- --- --- --- ---------
PJBIJE+AdvPSHEL-B                    Type 1C           WinAnsi          yes yes no    1177  0
PJBIKF+AdvPSHN-H                     Type 1C           WinAnsi          yes yes no    1181  0
PJBILG+AdvPSHN-HI                    Type 1C           WinAnsi          yes yes no    1183  0
PJBILH+AdvPSHN-M                     Type 1C           Custom           yes yes no    1186  0
PJBILI+AdvPSMPi6                     Type 1C           WinAnsi          yes yes no    1188  0
PJBILJ+AdvPSHN-MI                    Type 1C           WinAnsi          yes yes no    1190  0
PJBILK+AdvP4C4E59                    Type 1C           Custom           yes yes no    1194  0
PJBILL+AdvPSSym                      Type 1C           WinAnsi          yes yes no    1197  0
PJBILH+AdvPSHN-M                     Type 1C           Custom           yes yes no    1051  0
PJBIKF+AdvPSHN-H                     Type 1C           MacRoman         yes yes no    1057  0
PIHOMI+AdvPSA189                     Type 1C           WinAnsi          yes yes no    1050  0
PIHOMJ+Advhelvneue-bi                Type 1C           WinAnsi          yes yes no    1059  0
PJBILK+AdvP4C4E59                    Type 1C           Custom           yes yes no    1045  0
PIHONK+AdvPSA183                     Type 1C           Custom           yes yes no    1048  0
PJBILJ+AdvPSHN-MI                    Type 1C           WinAnsi          yes yes no    1010  0
PIHONM+Advhelvneue-italic            Type 1C           WinAnsi          yes yes no    1011  0
PJBILL+AdvPSSym                      Type 1C           WinAnsi          yes yes no    1024  0
PJBILG+AdvPSHN-HI                    Type 1C           WinAnsi          yes yes no    1062  0
PIHPDN+AdvP4C4E74                    Type 1C           Custom           yes yes yes   1066  0
PIHPPJ+Helvetica-Bold                Type 1C           WinAnsi          yes yes no    1071  0
PIIGKO+AdvPS3F4C13                   Type 1C           WinAnsi          yes yes no    1083  0
PIIHBM+AdvPS480274                   Type 1C           WinAnsi          yes yes no    1088  0
PJBILI+AdvPSMPi6                     Type 1C           WinAnsi          yes yes no    1087  0
PIIKAL+AdvPS4731B1                   Type 1C           WinAnsi          yes yes no    1101  0
PIIKKI+AdvPS3F64A9                   Type 1C           WinAnsi          yes yes no    1115  0


Jhove (Rel. 1.28.0, 2023-05-18)
 Date: 2026-01-29 03:09:33 CET
 RepresentationInformation: 2018_CurrentBiol_Carrete_etal.pdf
  ReportingModule: PDF-hul, Rel. 1.12.4 (2023-03-16)
  LastModified: 2026-01-28 06:15:48 CET
  Size: 3561512
  Format: PDF
  Version: 1.7
  Status: Well-Formed, but not valid
  SignatureMatches:
   PDF-hul
  ErrorMessage: Invalid indirect destination - referenced object 'mmc3' cannot be found
   ID: PDF-HUL-149
  ErrorMessage: Invalid indirect destination - referenced object 'mmc5' cannot be found
   ID: PDF-HUL-149
  ErrorMessage: Invalid indirect destination - referenced object 'mmc4' cannot be found
   ID: PDF-HUL-149
  ErrorMessage: Invalid indirect destination - referenced object 'mmc2' cannot be found
   ID: PDF-HUL-149
  ErrorMessage: Invalid indirect destination - referenced object 'mmc6' cannot be found
   ID: PDF-HUL-149
  ErrorMessage: Invalid indirect destination - referenced object 'mmc7' cannot be found
   ID: PDF-HUL-149
  ErrorMessage: Invalid indirect destination - referenced object 'mmc8' cannot be found
   ID: PDF-HUL-149
  ErrorMessage: Invalid indirect destination - referenced object 'mmc1' cannot be found
   ID: PDF-HUL-149
  ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'mmc4' cannot be found
   ID: PDF-HUL-122
   Offset: 3529034
  ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'mmc3' cannot be found
   ID: PDF-HUL-122
   Offset: 3529034
  ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'mmc7' cannot be found
   ID: PDF-HUL-122
   Offset: 3529034
  ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'mmc2' cannot be found
   ID: PDF-HUL-122
   Offset: 3529034
  ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'mmc8' cannot be found
   ID: PDF-HUL-122
   Offset: 3529034
  ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'mmc1' cannot be found
   ID: PDF-HUL-122
   Offset: 3529034
  ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'mmc6' cannot be found
   ID: PDF-HUL-122
   Offset: 3529034
  ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'mmc5' cannot be found
   ID: PDF-HUL-122
   Offset: 3529034
  MIMEtype: application/pdf
  Profile: Linearized PDF
  PDFMetadata: 
   Objects: 1269
   FreeObjects: 1
   IncrementalUpdates: 1
   DocumentCatalog: 
    PageLayout: SinglePage
    PageMode: UseOutlines
    Outlines: 
     Item: 
      Title: Patterns of Genomic Variation in the Opportunistic Pathogen Candida glabrata Suggest the Existence of Mating and a Secondar ...
      Destination: titlink1
      Children: 
       Item: 
        Title: Introduction
        Destination: flink1
       Item: 
        Title: Results and Discussion
        Destination: flink2
        Children: 
         Item: 
          Title: High Levels of Genetic Diversity between Clades and Lack of Strong Geographical Structure
          Destination: slink1
         Item: 
          Title: Genome Plasticity in C. glabrata: Extensive CNV and Presence of Aneuploidies and Re-arrangements
          Destination: slink2
         Item: 
          Title: Evidence for Genomic Recombination between Distinct Clades
          Destination: slink3
         Item: 
          Title: Genes Involved in Mating Are Evolutionarily Constrained at the Species Level
          Destination: slink4
         Item: 
          Title: Illegitimate Mating-type Switching
          Destination: slink5
         Item: 
          Title: Genomic Plasticity Enables Large Phenotypic Differences between and within Clades
          Destination: slink6
         Item: 
          Title: Conclusions
          Destination: slink7
       Item: 
        Title: Supplemental Information
        Destination: falink3
       Item: 
        Title: Acknowledgments
        Destination: acklink1
       Item: 
        Title: References
        Destination: blink1
       Item: 
        Title: STAR★Methods
        Destination: flink4
        Children: 
         Item: 
          Title: Key Resources Table
          Destination: slink8
         Item: 
          Title: Contact for Resource Sharing
          Destination: slink9
         Item: 
          Title: Experimental Model and Subject Details
          Destination: slink10
          Children: 
           Item: 
            Title: Strains
            Destination: tlink1
           Item: 
            Title: DNA extraction
            Destination: tlink2
         Item: 
          Title: Method Details
          Destination: slink11
          Children: 
           Item: 
            Title: Sequencing
            Destination: tlink3
           Item: 
            Title: Genome assembly
            Destination: tlink4
           Item: 
            Title: SNP calling
            Destination: tlink5
           Item: 
            Title: Structural variants
            Destination: tlink6
           Item: 
            Title: Experimental validation of CNVs
            Destination: tlink7
           Item: 
            Title: PCR amplification of mating-type regions and sequencing
            Destination: tlink8
           Item: 
            Title: Recombination estimates
            Destination: tlink9
           Item: 
            Title: Chromosomal rearrangements
            Destination: tlink10
           Item: 
            Title: Phylogenetic analysis
            Destination: tlink11
           Item: 
            Title: Population Genomics
            Destination: tlink12
           Item: 
            Title: Phenotypic analyses: Growth curves
            Destination: tlink13
           Item: 
            Title: Phenotypic analyses: biofilm formation assay
            Destination: tlink14
           Item: 
            Title: Antifungal drug susceptibility testing
            Destination: tlink15
           Item: 
            Title: Pulsed-field gel electrophoresis
            Destination: tlink16
         Item: 
          Title: Quantification and Statistical Analysis
          Destination: slink12
         Item: 
          Title: Data and Software Availability
          Destination: slink13
   Info: 
    Title: Patterns of Genomic Variation in the Opportunistic Pathogen Candida glabrata Suggest the Existence of Mating and a Secondary Association with Humans
    Author: Laia Carreté
    Subject: Current Biology, 28 (2018) 15-34. doi:10.1016/j.cub.2017.11.027
    Creator: Elsevier
    Producer: Acrobat Distiller 8.1.0 (Windows)
    CreationDate: Tue Jan 02 21:50:47 CET 2018
    ModDate: Wed Jan 03 06:05:47 CET 2018
   ID: 0x4a5cf7fb7de3ac9e9709aa0c3de94cdc, 0x87670c85b973d74d913951c48b578832
   Filters: 
    FilterPipeline: FlateDecode
    FilterPipeline: DCTDecode
   Images: 
    Image: 
     NisoImageMetadata: 
      FormatName: image/png
      ImageWidth: 68
      ImageHeight: 68
      ColorSpace: palette color
      BitsPerSample: 8
      BitsPerSampleUnit: integer
     Filter: FlateDecode
    Image: 
     NisoImageMetadata: 
      FormatName: image/png
      ImageWidth: 68
      ImageHeight: 68
      ColorSpace: palette color
      BitsPerSample: 8
      BitsPerSampleUnit: integer
     Filter: FlateDecode
    Image: 
     NisoImageMetadata: 
      FormatName: image/jpg
      CompressionScheme: JPEG
      ImageWidth: 856
      ImageHeight: 303
      BitsPerSample: 8
      BitsPerSampleUnit: integer
     ColorSpace: ICCBased
    Image: 
     NisoImageMetadata: 
      FormatName: image/jpg
      CompressionScheme: JPEG
      ImageWidth: 856
      ImageHeight: 295
      BitsPerSample: 8
      BitsPerSampleUnit: integer
     ColorSpace: ICCBased
    Image: 
     NisoImageMetadata: 
      FormatName: image/jpg
      CompressionScheme: JPEG
      ImageWidth: 715
      ImageHeight: 589
      BitsPerSample: 8
      BitsPerSampleUnit: integer
     ColorSpace: ICCBased
    Image: 
     NisoImageMetadata: 
      FormatName: image/png
      CompressionScheme: uncompressed
      ImageWidth: 1
      ImageHeight: 22
      BitsPerSample: 8
      BitsPerSampleUnit: integer
     ColorSpace: ICCBased
   Fonts: 
    Type1: 
     Font: 
      BaseFont: PJBILL+AdvPSSym
      FontSubset: true
      FirstChar: 170
      LastChar: 170
      FontDescriptor: 
       FontName: PJBILL+AdvPSSym
       Flags: Nonsymbolic
       FontBBox: -177, -291, 1083, 1010
       FontFile3: true
      Encoding: WinAnsiEncoding
     Font: 
      BaseFont: PIIHBM+AdvPS480274
      FontSubset: true
      FirstChar: 43
      LastChar: 66
      FontDescriptor: 
       FontName: PIIHBM+AdvPS480274
       Flags: Nonsymbolic
       FontBBox: 0, -208, 1354, 791
       FontFile3: true
      Encoding: WinAnsiEncoding
     Font: 
      BaseFont: PIIKAL+AdvPS4731B1
      FontSubset: true
      FirstChar: 82
      LastChar: 82
      FontDescriptor: 
       FontName: PIIKAL+AdvPS4731B1
       Flags: Nonsymbolic
       FontBBox: 0, -208, 1572, 802
       FontFile3: true
      Encoding: WinAnsiEncoding
     Font: 
      BaseFont: PJBILK+AdvP4C4E59
      FontSubset: true
      FirstChar: 1
      LastChar: 1
      FontDescriptor: 
       FontName: PJBILK+AdvP4C4E59
       Flags: Symbolic
       FontBBox: -31, -250, 1000, 750
       FontFile3: true
      EncodingDictionary: 
       Differences: true
     Font: 
      BaseFont: PIHONK+AdvPSA183
      FontSubset: true
      FirstChar: 25
      LastChar: 184
      FontDescriptor: 
       FontName: PIHONK+AdvPSA183
       Flags: Nonsymbolic
       FontBBox: -156, -208, 1072, 791
       FontFile3: true
      EncodingDictionary: 
       BaseEncoding: WinAnsiEncoding
       Differences: true
     Font: 
      BaseFont: PJBIJE+AdvPSHEL-B
      FontSubset: true
      FirstChar: 65
      LastChar: 116
      FontDescriptor: 
       FontName: PJBIJE+AdvPSHEL-B
       Flags: Nonsymbolic
       FontBBox: -166, -218, 1000, 770
       FontFile3: true
      Encoding: WinAnsiEncoding
     Font: 
      BaseFont: PIHOMI+AdvPSA189
      FontSubset: true
      FirstChar: 45
      LastChar: 122
      FontDescriptor: 
       FontName: PIHOMI+AdvPSA189
       Flags: Nonsymbolic
       FontBBox: -156, -208, 1072, 802
       FontFile3: true
      Encoding: WinAnsiEncoding
     Font: 
      BaseFont: PJBILH+AdvPSHN-M
      FontSubset: true
      FirstChar: 30
      LastChar: 180
      FontDescriptor: 
       FontName: PJBILH+AdvPSHN-M
       Flags: Nonsymbolic
       FontBBox: -156, -218, 1062, 802
       FontFile3: true
      EncodingDictionary: 
       BaseEncoding: WinAnsiEncoding
       Differences: true
     Font: 
      BaseFont: PIIKKI+AdvPS3F64A9
      FontSubset: true
      FirstChar: 53
      LastChar: 53
      FontDescriptor: 
       FontName: PIIKKI+AdvPS3F64A9
       Flags: Nonsymbolic
       FontBBox: -52, -239, 781, 677
       FontFile3: true
      Encoding: WinAnsiEncoding
     Font: 
      BaseFont: PJBIKF+AdvPSHN-H
      FontSubset: true
      FirstChar: 65
      LastChar: 121
      FontDescriptor: 
       FontName: PJBIKF+AdvPSHN-H
       Flags: Nonsymbolic
       FontBBox: -166, -229, 1093, 812
       FontFile3: true
      Encoding: WinAnsiEncoding
     Font: 
      BaseFont: PJBILG+AdvPSHN-HI
      FontSubset: true
      FirstChar: 67
      LastChar: 116
      FontDescriptor: 
       FontName: PJBILG+AdvPSHN-HI
       Flags: Nonsymbolic
       FontBBox: -156, -218, 1135, 791
       FontFile3: true
      Encoding: WinAnsiEncoding
     Font: 
      BaseFont: PJBIKF+AdvPSHN-H
      FontSubset: true
      FirstChar: 44
      LastChar: 222
      FontDescriptor: 
       FontName: PJBIKF+AdvPSHN-H
       Flags: Nonsymbolic
       FontBBox: -166, -229, 1093, 812
       FontFile3: true
      Encoding: MacRomanEncoding
     Font: 
      BaseFont: PJBILH+AdvPSHN-M
      FontSubset: true
      FirstChar: 30
      LastChar: 180
      FontDescriptor: 
       FontName: PJBILH+AdvPSHN-M
       Flags: Nonsymbolic
       FontBBox: -156, -218, 1062, 802
       FontFile3: true
      EncodingDictionary: 
       BaseEncoding: WinAnsiEncoding
       Differences: true
     Font: 
      BaseFont: PIHOMJ+Advhelvneue-bi
      FontSubset: true
      FirstChar: 46
      LastChar: 116
      FontDescriptor: 
       FontName: PIHOMJ+Advhelvneue-bi
       Flags: Nonsymbolic
       FontBBox: -156, -208, 1125, 802
       FontFile3: true
      Encoding: WinAnsiEncoding
     Font: 
      BaseFont: PJBILI+AdvPSMPi6
      FontSubset: true
      FirstChar: 100
      LastChar: 100
      FontDescriptor: 
       FontName: PJBILI+AdvPSMPi6
       Flags: Nonsymbolic
       FontBBox: 0, -177, 989, 739
       FontFile3: true
      Encoding: WinAnsiEncoding
     Font: 
      BaseFont: PJBILJ+AdvPSHN-MI
      FontSubset: true
      FirstChar: 46
      LastChar: 116
      FontDescriptor: 
       FontName: PJBILJ+AdvPSHN-MI
       Flags: Nonsymbolic
       FontBBox: -156, -208, 1125, 802
       FontFile3: true
      Encoding: WinAnsiEncoding
     Font: 
      BaseFont: PJBILG+AdvPSHN-HI
      FontSubset: true
      FirstChar: 46
      LastChar: 117
      FontDescriptor: 
       FontName: PJBILG+AdvPSHN-HI
       Flags: Nonsymbolic
       FontBBox: -156, -218, 1135, 791
       FontFile3: true
      Encoding: WinAnsiEncoding
     Font: 
      BaseFont: PJBILK+AdvP4C4E59
      FontSubset: true
      FirstChar: 1
      LastChar: 1
      FontDescriptor: 
       FontName: PJBILK+AdvP4C4E59
       Flags: Symbolic
       FontBBox: -31, -250, 1000, 750
       FontFile3: true
      EncodingDictionary: 
       Differences: true
     Font: 
      BaseFont: PIHPDN+AdvP4C4E74
      FontSubset: true
      FirstChar: 1
      LastChar: 48
      FontDescriptor: 
       FontName: PIHPDN+AdvP4C4E74
       Flags: Symbolic
       FontBBox: -20, -958, 1114, 770
       FontFile3: true
      EncodingDictionary: 
       Differences: true
      ToUnicode: true
     Font: 
      BaseFont: PJBILL+AdvPSSym
      FontSubset: true
      FirstChar: 170
      LastChar: 170
      FontDescriptor: 
       FontName: PJBILL+AdvPSSym
       Flags: Nonsymbolic
       FontBBox: -177, -291, 1083, 1010
       FontFile3: true
      Encoding: WinAnsiEncoding
     Font: 
      BaseFont: PIHPPJ+Helvetica-Bold
      FontSubset: true
      FirstChar: 65
      LastChar: 68
      FontDescriptor: 
       FontName: PIHPPJ+Helvetica-Bold
       Flags: Nonsymbolic, ForceBold
       FontBBox: -170, -228, 1003, 962
       FontFile3: true
      Encoding: WinAnsiEncoding
     Font: 
      BaseFont: PJBILJ+AdvPSHN-MI
      FontSubset: true
      FirstChar: 45
      LastChar: 121
      FontDescriptor: 
       FontName: PJBILJ+AdvPSHN-MI
       Flags: Nonsymbolic
       FontBBox: -156, -208, 1125, 802
       FontFile3: true
      Encoding: WinAnsiEncoding
     Font: 
      BaseFont: PIHONM+Advhelvneue-italic
      FontSubset: true
      FirstChar: 44
      LastChar: 121
      FontDescriptor: 
       FontName: PIHONM+Advhelvneue-italic
       Flags: Nonsymbolic
       FontBBox: -156, -208, 1104, 791
       FontFile3: true
      Encoding: WinAnsiEncoding
     Font: 
      BaseFont: PIIGKO+AdvPS3F4C13
      FontSubset: true
      FirstChar: 109
      LastChar: 112
      FontDescriptor: 
       FontName: PIIGKO+AdvPS3F4C13
       Flags: Nonsymbolic
       FontBBox: 0, -291, 875, 697
       FontFile3: true
      Encoding: WinAnsiEncoding
     Font: 
      BaseFont: PJBILI+AdvPSMPi6
      FontSubset: true
      FirstChar: 100
      LastChar: 100
      FontDescriptor: 
       FontName: PJBILI+AdvPSMPi6
       Flags: Nonsymbolic
       FontBBox: 0, -177, 989, 739
       FontFile3: true
      Encoding: WinAnsiEncoding
   XMP: <x:xmpmeta xmlns:x="adobe:ns:meta/" x:xmptk="Adobe XMP Core 4.0-c316 44.253921, Sun Oct 01 2006 17:14:39">
   <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#">
      <rdf:Description rdf:about=""
            xmlns:dc="http://purl.org/dc/elements/1.1/">
         <dc:format>application/pdf</dc:format>
         <dc:identifier>doi:10.1016/j.cub.2017.11.027</dc:identifier>
         <dc:title>
            <rdf:Alt>
               <rdf:li xml:lang="x-default">Patterns of Genomic Variation in the Opportunistic Pathogen Candida glabrata Suggest the Existence of Mating and a Secondary Association with Humans</rdf:li>
            </rdf:Alt>
         </dc:title>
         <dc:creator>
            <rdf:Seq>
               <rdf:li>Laia Carreté</rdf:li>
               <rdf:li>Ewa Ksiezopolska</rdf:li>
               <rdf:li>Cinta Pegueroles</rdf:li>
               <rdf:li>Emilia Gómez-Molero</rdf:li>
               <rdf:li>Ester Saus</rdf:li>
               <rdf:li>Susana Iraola-Guzmán</rdf:li>
               <rdf:li>Damian Loska</rdf:li>
               <rdf:li>Oliver Bader</rdf:li>
               <rdf:li>Cecile Fairhead</rdf:li>
               <rdf:li>Toni Gabaldón</rdf:li>
            </rdf:Seq>
         </dc:creator>
         <dc:subject>
            <rdf:Bag>
               <rdf:li>Candida glabrata</rdf:li>
               <rdf:li>mating</rdf:li>
               <rdf:li>evolution</rdf:li>
               <rdf:li>population genomics</rdf:li>
               <rdf:li>human fungal pathogens</rdf:li>
               <rdf:li>adhesion</rdf:li>
            </rdf:Bag>
         </dc:subject>
         <dc:description>
            <rdf:Alt>
               <rdf:li xml:lang="x-default">Current Biology, 28 (2018) 15-34. doi:10.1016/j.cub.2017.11.027</rdf:li>
            </rdf:Alt>
         </dc:description>
         <dc:publisher>
            <rdf:Bag>
               <rdf:li>Elsevier Ltd.</rdf:li>
            </rdf:Bag>
         </dc:publisher>
      </rdf:Description>
      <rdf:Description rdf:about=""
            xmlns:prism="http://prismstandard.org/namespaces/basic/3.0/">
         <prism:aggregationType>journal</prism:aggregationType>
         <prism:publicationName>Current Biology</prism:publicationName>
         <prism:copyright>© 2017 The Author(s). Published by Elsevier Ltd.</prism:copyright>
         <prism:issn>0960-9822</prism:issn>
         <prism:volume>28</prism:volume>
         <prism:number>1</prism:number>
         <prism:coverDisplayDate>8 January 2018</prism:coverDisplayDate>
         <prism:coverDate>2018-01-08</prism:coverDate>
         <prism:pageRange>15-27.e7</prism:pageRange>
         <prism:startingPage>15</prism:startingPage>
         <prism:endingPage>27.e7</prism:endingPage>
         <prism:doi>10.1016/j.cub.2017.11.027</prism:doi>
         <prism:url>https://doi.org/10.1016/j.cub.2017.11.027</prism:url>
      </rdf:Description>
      <rdf:Description rdf:about=""
            xmlns:crossmark="http://crossref.org/crossmark/1.0/">
         <crossmark:MajorVersionDate>2010-04-23</crossmark:MajorVersionDate>
         <crossmark:CrossmarkDomainExclusive>true</crossmark:CrossmarkDomainExclusive>
         <crossmark:DOI>10.1016/j.cub.2017.11.027</crossmark:DOI>
         <crossmark:CrossMarkDomains>
            <rdf:Seq>
               <rdf:li>elsevier.com</rdf:li>
               <rdf:li>sciencedirect.com</rdf:li>
            </rdf:Seq>
         </crossmark:CrossMarkDomains>
      </rdf:Description>
      <rdf:Description rdf:about=""
            xmlns:jav="http://www.niso.org/schemas/jav/1.0/">
         <jav:journal_article_version>VoR</jav:journal_article_version>
      </rdf:Description>
      <rdf:Description rdf:about=""
            xmlns:pdfx="http://ns.adobe.com/pdfx/1.3/">
         <pdfx:ElsevierWebPDFSpecifications>6.5</pdfx:ElsevierWebPDFSpecifications>
         <pdfx:doi>10.1016/j.cub.2017.11.027</pdfx:doi>
         <pdfx:robots>noindex</pdfx:robots>
         <pdfx:grabs>true</pdfx:grabs>
         <pdfx:CrossmarkMajorVersionDate>2010-04-23</pdfx:CrossmarkMajorVersionDate>
         <pdfx:CrossmarkDomainExclusive>true</pdfx:CrossmarkDomainExclusive>
         <pdfx:CrossMarkDomains>
            <rdf:Seq>
               <rdf:li>sciencedirect.com</rdf:li>
               <rdf:li>elsevier.com</rdf:li>
            </rdf:Seq>
         </pdfx:CrossMarkDomains>
      </rdf:Description>
      <rdf:Description rdf:about=""
            xmlns:xap="http://ns.adobe.com/xap/1.0/">
         <xap:CreatorTool>Elsevier</xap:CreatorTool>
         <xap:CreateDate>2018-01-03T01:50:47+05:30</xap:CreateDate>
         <xap:ModifyDate>2018-01-03T10:05:47+05:30</xap:ModifyDate>
         <xap:MetadataDate>2018-01-03T10:05:47+05:30</xap:MetadataDate>
      </rdf:Description>
      <rdf:Description rdf:about=""
            xmlns:xapRights="http://ns.adobe.com/xap/1.0/rights/">
         <xapRights:Marked>True</xapRights:Marked>
      </rdf:Description>
      <rdf:Description rdf:about=""
            xmlns:pdf="http://ns.adobe.com/pdf/1.3/">
         <pdf:Producer>Acrobat Distiller 8.1.0 (Windows)</pdf:Producer>
      </rdf:Description>
      <rdf:Description rdf:about=""
            xmlns:xapMM="http://ns.adobe.com/xap/1.0/mm/">
         <xapMM:DocumentID>uuid:791076d2-443a-4f77-912e-20c4ecf1ae99</xapMM:DocumentID>
         <xapMM:InstanceID>uuid:f92da638-5859-4a70-8e83-548063fe66de</xapMM:InstanceID>
      </rdf:Description>
      <rdf:Description rdf:about=""
            xmlns:ali="http://www.niso.org/schemas/ali/1.0/">
         <ali:license_ref>
            <rdf:Bag>
               <rdf:li rdf:parseType="Resource">
                  <ali:uri>http://creativecommons.org/licenses/by-nc-nd/4.0/</ali:uri>
               </rdf:li>
            </rdf:Bag>
         </ali:license_ref>
      </rdf:Description>
   </rdf:RDF>
</x:xmpmeta>
   Pages: 
    Page: 
     Label: 15
     Sequence: 1
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 354, 510, 438, 520
      Annotation: 
       Subtype: Link
       Rect: 103, 48, 264, 57
      Annotation: 
       Subtype: Link
       Rect: 53, 56, 69, 72
    Page: 
     Label: 16
     Sequence: 2
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 105, 599, 109, 608
       Destination: 1
      Annotation: 
       Subtype: Link
       Rect: 111, 599, 115, 608
       Destination: 1
      Annotation: 
       Subtype: Link
       Rect: 195, 599, 199, 608
       Destination: 1
      Annotation: 
       Subtype: Link
       Rect: 201, 599, 204, 608
       Destination: 1
      Annotation: 
       Subtype: Link
       Rect: 280, 599, 284, 608
       Destination: 1
      Annotation: 
       Subtype: Link
       Rect: 286, 599, 290, 608
       Destination: 1
      Annotation: 
       Subtype: Link
       Rect: 384, 599, 387, 608
       Destination: 1
      Annotation: 
       Subtype: Link
       Rect: 437, 599, 441, 608
       Destination: 1
      Annotation: 
       Subtype: Link
       Rect: 442, 599, 446, 608
       Destination: 1
      Annotation: 
       Subtype: Link
       Rect: 149, 589, 153, 598
       Destination: 1
      Annotation: 
       Subtype: Link
       Rect: 155, 589, 158, 598
       Destination: 1
      Annotation: 
       Subtype: Link
       Rect: 222, 589, 226, 598
       Destination: 1
      Annotation: 
       Subtype: Link
       Rect: 228, 589, 232, 598
       Destination: 1
      Annotation: 
       Subtype: Link
       Rect: 288, 589, 292, 598
       Destination: 1
      Annotation: 
       Subtype: Link
       Rect: 361, 589, 365, 598
       Destination: 1
      Annotation: 
       Subtype: Link
       Rect: 446, 589, 450, 598
       Destination: 1
      Annotation: 
       Subtype: Link
       Rect: 452, 589, 456, 598
       Destination: 1
      Annotation: 
       Subtype: Link
       Rect: 457, 589, 461, 598
       Destination: 1
      Annotation: 
       Subtype: Link
       Rect: 463, 589, 467, 598
       Destination: 1
      Annotation: 
       Subtype: Link
       Rect: 469, 589, 472, 598
       Destination: 1
      Annotation: 
       Subtype: Link
       Rect: 119, 509, 184, 517
      Annotation: 
       Subtype: Link
       Rect: 53, 499, 201, 507
      Annotation: 
       Subtype: Link
       Rect: 511, 464, 516, 473
       Destination: 307
      Annotation: 
       Subtype: Link
       Rect: 403, 432, 407, 440
       Destination: 307
      Annotation: 
       Subtype: Link
       Rect: 384, 388, 389, 396
       Destination: 307
      Annotation: 
       Subtype: Link
       Rect: 427, 355, 443, 363
       Destination: 307
      Annotation: 
       Subtype: Link
       Rect: 347, 311, 351, 319
       Destination: 307
      Annotation: 
       Subtype: Link
       Rect: 306, 190, 319, 199
       Destination: 307
      Annotation: 
       Subtype: Link
       Rect: 502, 147, 520, 155
       Destination: 307
      Annotation: 
       Subtype: Link
       Rect: 355, 114, 382, 122
       Destination: 307
      Annotation: 
       Subtype: Link
       Rect: 453, 92, 463, 100
       Destination: 307
      Annotation: 
       Subtype: Link
       Rect: 53, 16, 69, 32
      Annotation: 
       Subtype: Link
       Rect: 356, 9, 538, 17
    Page: 
     Label: 17
     Sequence: 3
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 237, 103, 257, 111
       Destination: 307
      Annotation: 
       Subtype: Link
       Rect: 265, 103, 294, 111
       Destination: 66
      Annotation: 
       Subtype: Link
       Rect: 498, 645, 506, 653
       Destination: 307
      Annotation: 
       Subtype: Link
       Rect: 498, 633, 502, 640
       Destination: 307
      Annotation: 
       Subtype: Link
       Rect: 498, 620, 502, 628
       Destination: 307
      Annotation: 
       Subtype: Link
       Rect: 498, 608, 506, 616
       Destination: 307
      Annotation: 
       Subtype: Link
       Rect: 498, 596, 506, 603
       Destination: 307
      Annotation: 
       Subtype: Link
       Rect: 498, 583, 502, 591
       Destination: 307
      Annotation: 
       Subtype: Link
       Rect: 498, 571, 502, 579
       Destination: 307
      Annotation: 
       Subtype: Link
       Rect: 498, 559, 506, 566
       Destination: 307
      Annotation: 
       Subtype: Link
       Rect: 498, 546, 502, 554
       Destination: 307
      Annotation: 
       Subtype: Link
       Rect: 498, 534, 506, 542
       Destination: 307
      Annotation: 
       Subtype: Link
       Rect: 498, 522, 502, 529
       Destination: 307
      Annotation: 
       Subtype: Link
       Rect: 498, 509, 506, 517
       Destination: 307
      Annotation: 
       Subtype: Link
       Rect: 498, 497, 502, 505
       Destination: 307
      Annotation: 
       Subtype: Link
       Rect: 498, 485, 506, 492
       Destination: 307
      Annotation: 
       Subtype: Link
       Rect: 498, 472, 502, 480
       Destination: 307
      Annotation: 
       Subtype: Link
       Rect: 498, 460, 506, 468
       Destination: 307
      Annotation: 
       Subtype: Link
       Rect: 498, 448, 506, 455
       Destination: 307
      Annotation: 
       Subtype: Link
       Rect: 87, 439, 90, 446
       Destination: 66
      Annotation: 
       Subtype: Link
       Rect: 498, 435, 506, 443
       Destination: 307
      Annotation: 
       Subtype: Link
       Rect: 86, 426, 89, 434
       Destination: 66
      Annotation: 
       Subtype: Link
       Rect: 498, 423, 506, 431
       Destination: 307
      Annotation: 
       Subtype: Link
       Rect: 87, 414, 90, 422
       Destination: 66
      Annotation: 
       Subtype: Link
       Rect: 498, 411, 506, 418
       Destination: 307
      Annotation: 
       Subtype: Link
       Rect: 498, 398, 502, 406
       Destination: 307
      Annotation: 
       Subtype: Link
       Rect: 498, 386, 502, 394
       Destination: 307
      Annotation: 
       Subtype: Link
       Rect: 498, 374, 502, 381
       Destination: 307
      Annotation: 
       Subtype: Link
       Rect: 498, 361, 502, 369
       Destination: 307
      Annotation: 
       Subtype: Link
       Rect: 88, 352, 91, 360
       Destination: 66
      Annotation: 
       Subtype: Link
       Rect: 498, 349, 506, 357
       Destination: 307
      Annotation: 
       Subtype: Link
       Rect: 498, 337, 502, 344
       Destination: 307
      Annotation: 
       Subtype: Link
       Rect: 498, 324, 502, 332
       Destination: 307
      Annotation: 
       Subtype: Link
       Rect: 498, 312, 502, 320
       Destination: 307
      Annotation: 
       Subtype: Link
       Rect: 498, 300, 502, 307
       Destination: 307
      Annotation: 
       Subtype: Link
       Rect: 498, 287, 502, 295
       Destination: 307
      Annotation: 
       Subtype: Link
       Rect: 498, 275, 502, 283
       Destination: 307
      Annotation: 
       Subtype: Link
       Rect: 498, 263, 502, 270
       Destination: 307
      Annotation: 
       Subtype: Link
       Rect: 498, 250, 506, 258
       Destination: 307
    Page: 
     Label: 18
     Sequence: 4
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 230, 201, 289, 210
       Destination: 794
      Annotation: 
       Subtype: Link
       Rect: 87, 179, 97, 188
       Destination: 307
      Annotation: 
       Subtype: Link
       Rect: 255, 81, 287, 89
       Destination: 114
      Annotation: 
       Subtype: Link
       Rect: 257, 37, 272, 45
       Destination: 307
      Annotation: 
       Subtype: Link
       Rect: 306, 158, 342, 166
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 147, 268, 170, 275
       Destination: 66
      Annotation: 
       Subtype: Link
       Rect: 81, 231, 115, 238
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 130, 231, 139, 238
       Destination: null
    Page: 
     Label: 19
     Sequence: 5
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 261, 651, 270, 659
       Destination: 307
      Annotation: 
       Subtype: Link
       Rect: 113, 618, 144, 626
       Destination: 114
      Annotation: 
       Subtype: Link
       Rect: 148, 618, 184, 626
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 257, 596, 280, 604
       Destination: 307
      Annotation: 
       Subtype: Link
       Rect: 284, 563, 298, 572
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 59, 552, 85, 561
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 101, 475, 111, 484
       Destination: 307
      Annotation: 
       Subtype: Link
       Rect: 123, 464, 133, 473
       Destination: 307
      Annotation: 
       Subtype: Link
       Rect: 215, 442, 274, 451
       Destination: 794
      Annotation: 
       Subtype: Link
       Rect: 206, 256, 263, 265
       Destination: 794
      Annotation: 
       Subtype: Link
       Rect: 284, 245, 298, 254
       Destination: 175
      Annotation: 
       Subtype: Link
       Rect: 59, 234, 78, 243
       Destination: 175
      Annotation: 
       Subtype: Link
       Rect: 82, 234, 111, 243
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 157, 223, 193, 232
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 151, 179, 160, 188
       Destination: 498
      Annotation: 
       Subtype: Link
       Rect: 258, 147, 294, 155
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 176, 103, 207, 111
       Destination: 175
      Annotation: 
       Subtype: Link
       Rect: 212, 103, 248, 111
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 209, 70, 247, 78
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 277, 70, 298, 78
       Destination: 794
      Annotation: 
       Subtype: Link
       Rect: 59, 59, 93, 67
       Destination: 794
      Annotation: 
       Subtype: Link
       Rect: 486, 629, 521, 637
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 394, 607, 404, 615
       Destination: 498
      Annotation: 
       Subtype: Link
       Rect: 503, 585, 539, 593
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 313, 519, 345, 528
       Destination: 194
      Annotation: 
       Subtype: Link
       Rect: 363, 497, 372, 506
       Destination: 307
      Annotation: 
       Subtype: Link
       Rect: 375, 453, 434, 462
       Destination: 794
      Annotation: 
       Subtype: Link
       Rect: 492, 190, 523, 199
       Destination: 220
      Annotation: 
       Subtype: Link
       Rect: 461, 125, 494, 133
       Destination: 220
      Annotation: 
       Subtype: Link
       Rect: 507, 125, 545, 133
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 313, 48, 344, 56
       Destination: 220
    Page: 
     Label: 20
     Sequence: 6
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 222, 114, 259, 122
       Destination: 175
      Annotation: 
       Subtype: Link
       Rect: 282, 114, 287, 122
       Destination: 194
      Annotation: 
       Subtype: Link
       Rect: 322, 147, 380, 155
       Destination: 794
      Annotation: 
       Subtype: Link
       Rect: 429, 92, 459, 100
       Destination: 220
      Annotation: 
       Subtype: Link
       Rect: 151, 236, 176, 243
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 81, 227, 127, 234
       Destination: null
    Page: 
     Label: 21
     Sequence: 7
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 236, 136, 296, 144
       Destination: 794
      Annotation: 
       Subtype: Link
       Rect: 59, 125, 94, 133
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 192, 114, 223, 122
       Destination: 242
      Annotation: 
       Subtype: Link
       Rect: 85, 81, 94, 89
       Destination: 307
      Annotation: 
       Subtype: Link
       Rect: 252, 70, 261, 78
       Destination: 307
      Annotation: 
       Subtype: Link
       Rect: 268, 59, 278, 67
       Destination: 498
      Annotation: 
       Subtype: Link
       Rect: 284, 59, 298, 67
       Destination: 242
      Annotation: 
       Subtype: Link
       Rect: 59, 48, 79, 56
       Destination: 242
      Annotation: 
       Subtype: Link
       Rect: 423, 522, 453, 529
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 397, 311, 430, 319
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 370, 223, 379, 232
       Destination: 498
      Annotation: 
       Subtype: Link
       Rect: 423, 136, 432, 144
       Destination: 498
      Annotation: 
       Subtype: Link
       Rect: 494, 70, 499, 78
       Destination: 307
    Page: 
     Label: 22
     Sequence: 8
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 55, 103, 86, 111
       Destination: 242
      Annotation: 
       Subtype: Link
       Rect: 198, 70, 230, 78
       Destination: 242
      Annotation: 
       Subtype: Link
       Rect: 241, 70, 278, 78
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 426, 48, 452, 56
       Destination: 498
      Annotation: 
       Subtype: Link
       Rect: 194, 278, 224, 285
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 67, 212, 114, 219
       Destination: 794
    Page: 
     Label: 23
     Sequence: 9
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 88, 72, 118, 78
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 134, 72, 165, 78
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 180, 72, 189, 78
       Destination: null
    Page: 
     Label: 24
     Sequence: 10
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 194, 585, 252, 593
       Destination: 794
      Annotation: 
       Subtype: Link
       Rect: 258, 585, 289, 593
       Destination: 286
      Annotation: 
       Subtype: Link
       Rect: 70, 574, 104, 582
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 214, 563, 245, 572
       Destination: 286
      Annotation: 
       Subtype: Link
       Rect: 196, 541, 230, 550
       Destination: 286
      Annotation: 
       Subtype: Link
       Rect: 158, 519, 193, 528
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 215, 486, 247, 495
       Destination: 286
      Annotation: 
       Subtype: Link
       Rect: 153, 464, 184, 473
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 154, 399, 187, 407
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 140, 366, 149, 374
       Destination: 498
      Annotation: 
       Subtype: Link
       Rect: 98, 333, 108, 341
       Destination: 498
      Annotation: 
       Subtype: Link
       Rect: 209, 234, 243, 243
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 187, 158, 217, 166
       Destination: 286
      Annotation: 
       Subtype: Link
       Rect: 55, 125, 64, 133
       Destination: 498
      Annotation: 
       Subtype: Link
       Rect: 442, 333, 447, 341
       Destination: 307
      Annotation: 
       Subtype: Link
       Rect: 325, 125, 424, 133
       Destination: 794
      Annotation: 
       Subtype: Link
       Rect: 325, 114, 473, 122
       Destination: 899
      Annotation: 
       Subtype: Link
       Rect: 325, 103, 517, 111
       Destination: 899
      Annotation: 
       Subtype: Link
       Rect: 325, 70, 397, 78
       Destination: 899
    Page: 
     Label: 25
     Sequence: 11
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 307, 103, 315, 110
       Destination: 498
      Annotation: 
       Subtype: Link
       Rect: 88, 94, 119, 101
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 123, 94, 131, 101
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 149, 94, 157, 101
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 173, 94, 198, 101
       Destination: null
    Page: 
     Label: 26
     Sequence: 12
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 74, 630, 260, 638
       Destination: 987
      Annotation: 
       Subtype: Link
       Rect: 74, 619, 220, 627
       Destination: 987
      Annotation: 
       Subtype: Link
       Rect: 217, 570, 292, 577
      Annotation: 
       Subtype: Link
       Rect: 53, 560, 108, 567
      Annotation: 
       Subtype: Link
       Rect: 65, 248, 292, 255
      Annotation: 
       Subtype: Link
       Rect: 65, 239, 292, 246
      Annotation: 
       Subtype: Link
       Rect: 65, 229, 116, 236
      Annotation: 
       Subtype: Link
       Rect: 65, 218, 292, 225
      Annotation: 
       Subtype: Link
       Rect: 65, 208, 292, 215
      Annotation: 
       Subtype: Link
       Rect: 65, 199, 235, 206
      Annotation: 
       Subtype: Link
       Rect: 65, 187, 292, 194
      Annotation: 
       Subtype: Link
       Rect: 65, 178, 292, 185
      Annotation: 
       Subtype: Link
       Rect: 65, 168, 292, 175
      Annotation: 
       Subtype: Link
       Rect: 65, 159, 252, 166
      Annotation: 
       Subtype: Link
       Rect: 65, 147, 150, 154
      Annotation: 
       Subtype: Link
       Rect: 154, 147, 292, 154
      Annotation: 
       Subtype: Link
       Rect: 65, 138, 292, 145
      Annotation: 
       Subtype: Link
       Rect: 65, 129, 155, 136
      Annotation: 
       Subtype: Link
       Rect: 65, 117, 292, 124
      Annotation: 
       Subtype: Link
       Rect: 65, 108, 292, 115
      Annotation: 
       Subtype: Link
       Rect: 65, 98, 156, 105
      Annotation: 
       Subtype: Link
       Rect: 65, 87, 292, 94
      Annotation: 
       Subtype: Link
       Rect: 65, 77, 292, 84
      Annotation: 
       Subtype: Link
       Rect: 65, 68, 119, 75
      Annotation: 
       Subtype: Link
       Rect: 65, 56, 292, 63
      Annotation: 
       Subtype: Link
       Rect: 65, 47, 292, 54
      Annotation: 
       Subtype: Link
       Rect: 65, 37, 221, 44
      Annotation: 
       Subtype: Link
       Rect: 316, 674, 543, 681
      Annotation: 
       Subtype: Link
       Rect: 316, 665, 543, 672
      Annotation: 
       Subtype: Link
       Rect: 316, 655, 543, 662
      Annotation: 
       Subtype: Link
       Rect: 316, 646, 466, 653
      Annotation: 
       Subtype: Link
       Rect: 316, 633, 543, 640
      Annotation: 
       Subtype: Link
       Rect: 316, 623, 543, 630
      Annotation: 
       Subtype: Link
       Rect: 316, 614, 445, 621
      Annotation: 
       Subtype: Link
       Rect: 316, 601, 543, 608
      Annotation: 
       Subtype: Link
       Rect: 316, 592, 543, 599
      Annotation: 
       Subtype: Link
       Rect: 316, 582, 543, 589
      Annotation: 
       Subtype: Link
       Rect: 316, 573, 429, 580
      Annotation: 
       Subtype: Link
       Rect: 316, 560, 543, 567
      Annotation: 
       Subtype: Link
       Rect: 316, 551, 543, 558
      Annotation: 
       Subtype: Link
       Rect: 316, 541, 543, 548
      Annotation: 
       Subtype: Link
       Rect: 316, 532, 395, 539
      Annotation: 
       Subtype: Link
       Rect: 316, 519, 543, 526
      Annotation: 
       Subtype: Link
       Rect: 316, 509, 543, 516
      Annotation: 
       Subtype: Link
       Rect: 316, 500, 543, 507
      Annotation: 
       Subtype: Link
       Rect: 316, 490, 478, 497
      Annotation: 
       Subtype: Link
       Rect: 316, 478, 543, 485
      Annotation: 
       Subtype: Link
       Rect: 316, 468, 543, 475
      Annotation: 
       Subtype: Link
       Rect: 316, 459, 543, 466
      Annotation: 
       Subtype: Link
       Rect: 316, 449, 360, 456
      Annotation: 
       Subtype: Link
       Rect: 316, 436, 543, 443
      Annotation: 
       Subtype: Link
       Rect: 316, 427, 543, 434
      Annotation: 
       Subtype: Link
       Rect: 316, 417, 509, 424
      Annotation: 
       Subtype: Link
       Rect: 316, 405, 543, 412
      Annotation: 
       Subtype: Link
       Rect: 316, 395, 543, 402
      Annotation: 
       Subtype: Link
       Rect: 316, 386, 543, 393
      Annotation: 
       Subtype: Link
       Rect: 316, 376, 543, 383
      Annotation: 
       Subtype: Link
       Rect: 316, 367, 543, 374
      Annotation: 
       Subtype: Link
       Rect: 316, 357, 351, 364
      Annotation: 
       Subtype: Link
       Rect: 316, 345, 543, 352
      Annotation: 
       Subtype: Link
       Rect: 316, 335, 543, 342
      Annotation: 
       Subtype: Link
       Rect: 316, 326, 404, 333
      Annotation: 
       Subtype: Link
       Rect: 316, 313, 412, 320
      Annotation: 
       Subtype: Link
       Rect: 416, 313, 543, 320
      Annotation: 
       Subtype: Link
       Rect: 316, 303, 543, 310
      Annotation: 
       Subtype: Link
       Rect: 316, 294, 543, 301
      Annotation: 
       Subtype: Link
       Rect: 316, 284, 543, 291
      Annotation: 
       Subtype: Link
       Rect: 316, 275, 373, 282
      Annotation: 
       Subtype: Link
       Rect: 316, 262, 543, 269
      Annotation: 
       Subtype: Link
       Rect: 316, 253, 543, 260
      Annotation: 
       Subtype: Link
       Rect: 316, 243, 543, 250
      Annotation: 
       Subtype: Link
       Rect: 316, 234, 351, 241
      Annotation: 
       Subtype: Link
       Rect: 316, 221, 543, 228
      Annotation: 
       Subtype: Link
       Rect: 316, 212, 465, 219
      Annotation: 
       Subtype: Link
       Rect: 469, 212, 543, 219
      Annotation: 
       Subtype: Link
       Rect: 316, 202, 487, 209
      Annotation: 
       Subtype: Link
       Rect: 316, 189, 543, 196
      Annotation: 
       Subtype: Link
       Rect: 316, 180, 543, 187
      Annotation: 
       Subtype: Link
       Rect: 316, 170, 543, 177
      Annotation: 
       Subtype: Link
       Rect: 316, 161, 336, 168
      Annotation: 
       Subtype: Link
       Rect: 316, 148, 543, 155
      Annotation: 
       Subtype: Link
       Rect: 316, 139, 543, 146
      Annotation: 
       Subtype: Link
       Rect: 316, 129, 543, 136
      Annotation: 
       Subtype: Link
       Rect: 316, 120, 543, 127
      Annotation: 
       Subtype: Link
       Rect: 316, 110, 504, 117
      Annotation: 
       Subtype: Link
       Rect: 316, 97, 543, 104
      Annotation: 
       Subtype: Link
       Rect: 316, 88, 543, 95
      Annotation: 
       Subtype: Link
       Rect: 316, 79, 389, 86
      Annotation: 
       Subtype: Link
       Rect: 316, 66, 543, 73
      Annotation: 
       Subtype: Link
       Rect: 316, 56, 543, 63
      Annotation: 
       Subtype: Link
       Rect: 316, 47, 543, 54
      Annotation: 
       Subtype: Link
       Rect: 316, 37, 343, 44
    Page: 
     Label: 27
     Sequence: 13
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 72, 674, 298, 681
      Annotation: 
       Subtype: Link
       Rect: 72, 665, 298, 672
      Annotation: 
       Subtype: Link
       Rect: 72, 655, 156, 662
      Annotation: 
       Subtype: Link
       Rect: 72, 643, 298, 650
      Annotation: 
       Subtype: Link
       Rect: 72, 634, 298, 641
      Annotation: 
       Subtype: Link
       Rect: 72, 624, 298, 631
      Annotation: 
       Subtype: Link
       Rect: 72, 615, 298, 622
      Annotation: 
       Subtype: Link
       Rect: 72, 605, 138, 612
      Annotation: 
       Subtype: Link
       Rect: 72, 593, 298, 600
      Annotation: 
       Subtype: Link
       Rect: 72, 584, 298, 591
      Annotation: 
       Subtype: Link
       Rect: 72, 574, 298, 581
      Annotation: 
       Subtype: Link
       Rect: 72, 565, 106, 572
      Annotation: 
       Subtype: Link
       Rect: 72, 553, 298, 560
      Annotation: 
       Subtype: Link
       Rect: 72, 543, 298, 550
      Annotation: 
       Subtype: Link
       Rect: 72, 534, 298, 541
      Annotation: 
       Subtype: Link
       Rect: 72, 525, 149, 532
      Annotation: 
       Subtype: Link
       Rect: 72, 513, 298, 520
      Annotation: 
       Subtype: Link
       Rect: 72, 503, 298, 510
      Annotation: 
       Subtype: Link
       Rect: 72, 494, 196, 501
      Annotation: 
       Subtype: Link
       Rect: 72, 482, 298, 489
      Annotation: 
       Subtype: Link
       Rect: 72, 472, 298, 479
      Annotation: 
       Subtype: Link
       Rect: 72, 463, 298, 470
      Annotation: 
       Subtype: Link
       Rect: 72, 453, 131, 460
      Annotation: 
       Subtype: Link
       Rect: 72, 441, 298, 448
      Annotation: 
       Subtype: Link
       Rect: 72, 432, 298, 439
      Annotation: 
       Subtype: Link
       Rect: 72, 422, 298, 429
      Annotation: 
       Subtype: Link
       Rect: 72, 413, 298, 420
      Annotation: 
       Subtype: Link
       Rect: 72, 403, 244, 410
      Annotation: 
       Subtype: Link
       Rect: 72, 391, 298, 398
      Annotation: 
       Subtype: Link
       Rect: 72, 382, 298, 389
      Annotation: 
       Subtype: Link
       Rect: 72, 372, 298, 379
      Annotation: 
       Subtype: Link
       Rect: 72, 363, 218, 370
      Annotation: 
       Subtype: Link
       Rect: 72, 351, 298, 358
      Annotation: 
       Subtype: Link
       Rect: 72, 342, 298, 349
      Annotation: 
       Subtype: Link
       Rect: 72, 332, 298, 339
      Annotation: 
       Subtype: Link
       Rect: 72, 323, 298, 330
      Annotation: 
       Subtype: Link
       Rect: 72, 313, 132, 320
      Annotation: 
       Subtype: Link
       Rect: 72, 301, 298, 308
      Annotation: 
       Subtype: Link
       Rect: 72, 292, 298, 299
      Annotation: 
       Subtype: Link
       Rect: 72, 282, 201, 289
      Annotation: 
       Subtype: Link
       Rect: 72, 270, 298, 277
      Annotation: 
       Subtype: Link
       Rect: 72, 261, 277, 268
      Annotation: 
       Subtype: Link
       Rect: 72, 249, 298, 256
      Annotation: 
       Subtype: Link
       Rect: 72, 239, 298, 246
      Annotation: 
       Subtype: Link
       Rect: 72, 230, 253, 237
      Annotation: 
       Subtype: Link
       Rect: 72, 218, 298, 225
      Annotation: 
       Subtype: Link
       Rect: 72, 208, 298, 215
      Annotation: 
       Subtype: Link
       Rect: 72, 199, 298, 206
      Annotation: 
       Subtype: Link
       Rect: 72, 189, 241, 196
      Annotation: 
       Subtype: Link
       Rect: 72, 177, 298, 184
      Annotation: 
       Subtype: Link
       Rect: 72, 168, 298, 175
      Annotation: 
       Subtype: Link
       Rect: 72, 159, 184, 165
      Annotation: 
       Subtype: Link
       Rect: 72, 147, 298, 153
      Annotation: 
       Subtype: Link
       Rect: 72, 137, 298, 144
      Annotation: 
       Subtype: Link
       Rect: 72, 128, 298, 135
      Annotation: 
       Subtype: Link
       Rect: 72, 118, 298, 125
      Annotation: 
       Subtype: Link
       Rect: 72, 109, 118, 116
      Annotation: 
       Subtype: Link
       Rect: 72, 97, 298, 104
      Annotation: 
       Subtype: Link
       Rect: 72, 87, 247, 94
      Annotation: 
       Subtype: Link
       Rect: 72, 75, 298, 82
      Annotation: 
       Subtype: Link
       Rect: 72, 66, 298, 73
      Annotation: 
       Subtype: Link
       Rect: 72, 56, 298, 63
      Annotation: 
       Subtype: Link
       Rect: 72, 47, 298, 54
      Annotation: 
       Subtype: Link
       Rect: 72, 37, 118, 44
      Annotation: 
       Subtype: Link
       Rect: 323, 674, 549, 681
      Annotation: 
       Subtype: Link
       Rect: 323, 665, 549, 672
      Annotation: 
       Subtype: Link
       Rect: 323, 655, 549, 662
      Annotation: 
       Subtype: Link
       Rect: 323, 646, 471, 653
      Annotation: 
       Subtype: Link
       Rect: 323, 633, 549, 640
      Annotation: 
       Subtype: Link
       Rect: 323, 624, 549, 631
      Annotation: 
       Subtype: Link
       Rect: 323, 614, 549, 621
      Annotation: 
       Subtype: Link
       Rect: 323, 605, 549, 612
      Annotation: 
       Subtype: Link
       Rect: 323, 595, 377, 602
      Annotation: 
       Subtype: Link
       Rect: 323, 583, 549, 590
      Annotation: 
       Subtype: Link
       Rect: 323, 573, 549, 580
      Annotation: 
       Subtype: Link
       Rect: 323, 564, 549, 571
      Annotation: 
       Subtype: Link
       Rect: 323, 554, 416, 561
      Annotation: 
       Subtype: Link
       Rect: 323, 542, 549, 549
      Annotation: 
       Subtype: Link
       Rect: 323, 532, 549, 539
      Annotation: 
       Subtype: Link
       Rect: 323, 523, 488, 530
      Annotation: 
       Subtype: Link
       Rect: 323, 510, 549, 517
      Annotation: 
       Subtype: Link
       Rect: 323, 501, 484, 508
      Annotation: 
       Subtype: Link
       Rect: 323, 488, 549, 495
      Annotation: 
       Subtype: Link
       Rect: 323, 479, 549, 486
      Annotation: 
       Subtype: Link
       Rect: 323, 469, 549, 476
      Annotation: 
       Subtype: Link
       Rect: 323, 460, 357, 467
      Annotation: 
       Subtype: Link
       Rect: 323, 447, 549, 454
      Annotation: 
       Subtype: Link
       Rect: 323, 438, 500, 445
      Annotation: 
       Subtype: Link
       Rect: 323, 425, 549, 432
      Annotation: 
       Subtype: Link
       Rect: 323, 416, 549, 423
      Annotation: 
       Subtype: Link
       Rect: 323, 406, 386, 413
      Annotation: 
       Subtype: Link
       Rect: 323, 394, 549, 400
      Annotation: 
       Subtype: Link
       Rect: 323, 384, 483, 391
      Annotation: 
       Subtype: Link
       Rect: 323, 371, 549, 378
      Annotation: 
       Subtype: Link
       Rect: 323, 362, 549, 369
      Annotation: 
       Subtype: Link
       Rect: 323, 353, 414, 360
      Annotation: 
       Subtype: Link
       Rect: 323, 340, 549, 347
      Annotation: 
       Subtype: Link
       Rect: 323, 330, 549, 337
      Annotation: 
       Subtype: Link
       Rect: 323, 321, 430, 328
      Annotation: 
       Subtype: Link
       Rect: 323, 308, 549, 315
      Annotation: 
       Subtype: Link
       Rect: 323, 299, 508, 306
      Annotation: 
       Subtype: Link
       Rect: 323, 286, 362, 293
      Annotation: 
       Subtype: Link
       Rect: 366, 286, 549, 293
      Annotation: 
       Subtype: Link
       Rect: 323, 277, 549, 284
      Annotation: 
       Subtype: Link
       Rect: 323, 267, 464, 274
      Annotation: 
       Subtype: Link
       Rect: 323, 255, 549, 262
      Annotation: 
       Subtype: Link
       Rect: 323, 245, 549, 252
      Annotation: 
       Subtype: Link
       Rect: 323, 236, 408, 243
      Annotation: 
       Subtype: Link
       Rect: 323, 223, 549, 230
      Annotation: 
       Subtype: Link
       Rect: 323, 214, 549, 221
      Annotation: 
       Subtype: Link
       Rect: 323, 204, 440, 211
      Annotation: 
       Subtype: Link
       Rect: 323, 192, 549, 199
      Annotation: 
       Subtype: Link
       Rect: 323, 182, 549, 189
      Annotation: 
       Subtype: Link
       Rect: 323, 173, 463, 180
      Annotation: 
       Subtype: Link
       Rect: 323, 160, 549, 167
      Annotation: 
       Subtype: Link
       Rect: 323, 151, 549, 158
      Annotation: 
       Subtype: Link
       Rect: 323, 141, 393, 148
      Annotation: 
       Subtype: Link
       Rect: 447, 129, 549, 136
      Annotation: 
       Subtype: Link
       Rect: 323, 119, 384, 126
      Annotation: 
       Subtype: Link
       Rect: 323, 107, 549, 114
      Annotation: 
       Subtype: Link
       Rect: 323, 97, 549, 104
      Annotation: 
       Subtype: Link
       Rect: 323, 88, 549, 95
      Annotation: 
       Subtype: Link
       Rect: 323, 78, 406, 85
      Annotation: 
       Subtype: Link
       Rect: 323, 66, 549, 73
      Annotation: 
       Subtype: Link
       Rect: 323, 56, 549, 63
      Annotation: 
       Subtype: Link
       Rect: 323, 47, 549, 54
      Annotation: 
       Subtype: Link
       Rect: 323, 37, 408, 44
    Page: 
     Label: 28
     Sequence: 14
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 65, 674, 292, 681
      Annotation: 
       Subtype: Link
       Rect: 65, 665, 292, 672
      Annotation: 
       Subtype: Link
       Rect: 65, 655, 220, 662
      Annotation: 
       Subtype: Link
       Rect: 65, 644, 292, 651
      Annotation: 
       Subtype: Link
       Rect: 65, 634, 292, 641
      Annotation: 
       Subtype: Link
       Rect: 65, 625, 180, 632
      Annotation: 
       Subtype: Link
       Rect: 316, 674, 543, 681
      Annotation: 
       Subtype: Link
       Rect: 316, 665, 543, 672
      Annotation: 
       Subtype: Link
       Rect: 316, 655, 543, 662
      Annotation: 
       Subtype: Link
       Rect: 316, 646, 543, 653
      Annotation: 
       Subtype: Link
       Rect: 316, 636, 543, 643
      Annotation: 
       Subtype: Link
       Rect: 316, 627, 352, 634
    Page: 
     Label: 27.e1
     Sequence: 15
    Page: 
     Label: 27.e2
     Sequence: 16
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 280, 524, 288, 531
       Destination: 307
      Annotation: 
       Subtype: Link
       Rect: 280, 511, 288, 519
       Destination: 307
      Annotation: 
       Subtype: Link
       Rect: 280, 499, 288, 507
       Destination: 307
      Annotation: 
       Subtype: Link
       Rect: 280, 80, 288, 87
       Destination: 307
    Page: 
     Label: 27.e3
     Sequence: 17
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 287, 353, 295, 360
       Destination: 498
      Annotation: 
       Subtype: Link
       Rect: 405, 353, 492, 360
      Annotation: 
       Subtype: Link
       Rect: 405, 343, 489, 350
      Annotation: 
       Subtype: Link
       Rect: 287, 330, 295, 338
       Destination: 498
      Annotation: 
       Subtype: Link
       Rect: 405, 330, 511, 338
      Annotation: 
       Subtype: Link
       Rect: 405, 320, 454, 328
      Annotation: 
       Subtype: Link
       Rect: 287, 308, 295, 315
       Destination: 498
      Annotation: 
       Subtype: Link
       Rect: 405, 308, 502, 315
      Annotation: 
       Subtype: Link
       Rect: 287, 296, 295, 303
       Destination: 498
      Annotation: 
       Subtype: Link
       Rect: 405, 296, 506, 303
      Annotation: 
       Subtype: Link
       Rect: 405, 286, 438, 293
      Annotation: 
       Subtype: Link
       Rect: 287, 273, 295, 281
       Destination: 498
      Annotation: 
       Subtype: Link
       Rect: 405, 273, 468, 281
      Annotation: 
       Subtype: Link
       Rect: 287, 261, 295, 269
       Destination: 498
      Annotation: 
       Subtype: Link
       Rect: 405, 261, 510, 269
      Annotation: 
       Subtype: Link
       Rect: 405, 249, 503, 256
      Annotation: 
       Subtype: Link
       Rect: 287, 236, 307, 244
       Destination: 498
      Annotation: 
       Subtype: Link
       Rect: 405, 236, 508, 244
      Annotation: 
       Subtype: Link
       Rect: 405, 226, 436, 234
      Annotation: 
       Subtype: Link
       Rect: 287, 214, 307, 222
       Destination: 498
      Annotation: 
       Subtype: Link
       Rect: 405, 214, 513, 222
      Annotation: 
       Subtype: Link
       Rect: 287, 202, 295, 209
       Destination: 498
      Annotation: 
       Subtype: Link
       Rect: 405, 202, 499, 209
      Annotation: 
       Subtype: Link
       Rect: 287, 189, 295, 197
       Destination: 498
      Annotation: 
       Subtype: Link
       Rect: 405, 189, 529, 197
      Annotation: 
       Subtype: Link
       Rect: 405, 179, 435, 187
      Annotation: 
       Subtype: Link
       Rect: 287, 167, 307, 175
       Destination: 498
      Annotation: 
       Subtype: Link
       Rect: 405, 167, 491, 175
      Annotation: 
       Subtype: Link
       Rect: 497, 167, 521, 175
      Annotation: 
       Subtype: Link
       Rect: 405, 157, 433, 165
      Annotation: 
       Subtype: Link
       Rect: 287, 145, 295, 152
       Destination: 498
      Annotation: 
       Subtype: Link
       Rect: 405, 145, 491, 152
      Annotation: 
       Subtype: Link
       Rect: 287, 133, 295, 140
       Destination: 498
      Annotation: 
       Subtype: Link
       Rect: 405, 133, 537, 140
      Annotation: 
       Subtype: Link
       Rect: 287, 120, 295, 128
       Destination: 498
      Annotation: 
       Subtype: Link
       Rect: 405, 120, 505, 128
      Annotation: 
       Subtype: Link
       Rect: 287, 108, 295, 115
       Destination: 498
      Annotation: 
       Subtype: Link
       Rect: 405, 108, 505, 115
      Annotation: 
       Subtype: Link
       Rect: 287, 95, 295, 103
       Destination: 498
      Annotation: 
       Subtype: Link
       Rect: 405, 95, 518, 103
      Annotation: 
       Subtype: Link
       Rect: 287, 83, 295, 91
       Destination: 498
      Annotation: 
       Subtype: Link
       Rect: 405, 83, 517, 91
      Annotation: 
       Subtype: Link
       Rect: 405, 73, 457, 81
      Annotation: 
       Subtype: Link
       Rect: 287, 61, 295, 68
       Destination: 498
      Annotation: 
       Subtype: Link
       Rect: 405, 61, 512, 68
      Annotation: 
       Subtype: Link
       Rect: 405, 51, 494, 58
    Page: 
     Label: 27.e4
     Sequence: 18
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 113, 423, 195, 431
      Annotation: 
       Subtype: Link
       Rect: 371, 368, 399, 377
       Destination: 66
      Annotation: 
       Subtype: Link
       Rect: 428, 357, 451, 366
       Destination: 307
      Annotation: 
       Subtype: Link
       Rect: 280, 645, 288, 652
       Destination: 498
      Annotation: 
       Subtype: Link
       Rect: 398, 645, 492, 652
      Annotation: 
       Subtype: Link
       Rect: 398, 635, 474, 642
      Annotation: 
       Subtype: Link
       Rect: 280, 622, 288, 630
       Destination: 498
      Annotation: 
       Subtype: Link
       Rect: 398, 622, 492, 630
      Annotation: 
       Subtype: Link
       Rect: 398, 612, 476, 620
      Annotation: 
       Subtype: Link
       Rect: 280, 600, 288, 608
       Destination: 498
      Annotation: 
       Subtype: Link
       Rect: 398, 600, 492, 608
      Annotation: 
       Subtype: Link
       Rect: 398, 590, 457, 598
      Annotation: 
       Subtype: Link
       Rect: 280, 578, 288, 585
       Destination: 498
      Annotation: 
       Subtype: Link
       Rect: 398, 578, 492, 585
      Annotation: 
       Subtype: Link
       Rect: 398, 568, 448, 575
      Annotation: 
       Subtype: Link
       Rect: 398, 543, 484, 551
      Annotation: 
       Subtype: Link
       Rect: 398, 533, 431, 541
    Page: 
     Label: 27.e5
     Sequence: 19
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 193, 651, 202, 659
       Destination: 498
      Annotation: 
       Subtype: Link
       Rect: 166, 640, 176, 648
       Destination: 498
      Annotation: 
       Subtype: Link
       Rect: 255, 640, 264, 648
       Destination: 498
      Annotation: 
       Subtype: Link
       Rect: 190, 629, 199, 637
       Destination: 498
      Annotation: 
       Subtype: Link
       Rect: 137, 618, 147, 626
       Destination: 498
      Annotation: 
       Subtype: Link
       Rect: 332, 574, 341, 582
       Destination: 307
      Annotation: 
       Subtype: Link
       Rect: 135, 563, 144, 572
       Destination: 498
      Annotation: 
       Subtype: Link
       Rect: 131, 552, 140, 561
       Destination: 307
      Annotation: 
       Subtype: Link
       Rect: 267, 552, 378, 561
      Annotation: 
       Subtype: Link
       Rect: 212, 519, 235, 528
       Destination: 498
      Annotation: 
       Subtype: Link
       Rect: 304, 442, 313, 451
       Destination: 498
      Annotation: 
       Subtype: Link
       Rect: 331, 432, 354, 440
       Destination: 498
      Annotation: 
       Subtype: Link
       Rect: 441, 355, 472, 363
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 193, 322, 228, 330
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 252, 300, 288, 309
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 469, 289, 505, 298
       Destination: null
      Annotation: 
       Subtype: Link
       Rect: 485, 158, 526, 166
       Destination: null
    Page: 
     Label: 27.e6
     Sequence: 20
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 315, 563, 324, 572
       Destination: 498
      Annotation: 
       Subtype: Link
       Rect: 465, 530, 475, 539
       Destination: 498
      Annotation: 
       Subtype: Link
       Rect: 300, 497, 323, 506
       Destination: 498
      Annotation: 
       Subtype: Link
       Rect: 189, 486, 198, 495
       Destination: 761
      Annotation: 
       Subtype: Link
       Rect: 326, 486, 335, 495
       Destination: 498
      Annotation: 
       Subtype: Link
       Rect: 529, 432, 538, 440
       Destination: 498
      Annotation: 
       Subtype: Link
       Rect: 297, 421, 306, 429
       Destination: 498
      Annotation: 
       Subtype: Link
       Rect: 150, 377, 155, 385
       Destination: 307
      Annotation: 
       Subtype: Link
       Rect: 81, 355, 90, 363
       Destination: 498
      Annotation: 
       Subtype: Link
       Rect: 319, 355, 328, 363
       Destination: 498
      Annotation: 
       Subtype: Link
       Rect: 469, 344, 479, 352
       Destination: 498
      Annotation: 
       Subtype: Link
       Rect: 393, 256, 402, 265
       Destination: 498
      Annotation: 
       Subtype: Link
       Rect: 199, 245, 208, 254
       Destination: 498
      Annotation: 
       Subtype: Link
       Rect: 249, 223, 258, 232
       Destination: 761
      Annotation: 
       Subtype: Link
       Rect: 273, 48, 282, 56
       Destination: 498
    Page: 
     Label: 27.e7
     Sequence: 21
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 318, 662, 328, 670
       Destination: 498
      Annotation: 
       Subtype: Link
       Rect: 195, 519, 205, 528
       Destination: 761
      Annotation: 
       Subtype: Link
       Rect: 506, 519, 549, 528
      Annotation: 
       Subtype: Link
       Rect: 59, 508, 546, 517
      Annotation: 
       Subtype: Link
       Rect: 462, 464, 472, 473
       Destination: 498
      Annotation: 
       Subtype: Link
       Rect: 436, 377, 446, 385
       Destination: 498
      Annotation: 
       Subtype: Link
       Rect: 113, 355, 122, 363
       Destination: 498
  Checksum: b8abee3f
   Type: CRC32
  Checksum: c5e624bba5f7a73850526cfc18d120c6
   Type: MD5
  Checksum: 186990e0af176dbc6adcaaba5af218230e37993d
   Type: SHA-1
  Checksum: 13cab8eafe7bcdda8a4b194acc9b5b82bac39ed2da50936e85da6fe113c4c795
   Type: SHA-256