d303286ce0b02f199fc97b0c616be906 pmc_35083241.pdf 5943a260d3678fc37847f20d4bda9dda07a40f99 pmc_35083241.pdf cb7a229b54c704bf5e0fbc8575e01b7012f79e6524c90468141577b810a166e2 pmc_35083241.pdf Title: Cytokine Hemoadsorption as Rescue Therapy for Critically Ill Patients With SARS-CoV-2 Pneumonia With Severe Respiratory Failure and Hypercytokinemia Subject: Introduction: A dysregulated inflammatory response, known as ``cytokine storm'', plays an important role in the pathophysiology of coronavirus 2019 disease (COVID-19). Keywords: SARS-CoV-2 pneumonia, hemoadsorption, acute respiratory distress syndrome (ARDS), hypercytokinemia, COVID-19 Author: Luis Chiscano-Camón Creator: LaTeX with hyperref package + hypdvips Producer: dvips + MiKTeX GPL Ghostscript 9.0 CreationDate: Tue Jan 4 16:01:11 2022 CET ModDate: Tue Jan 4 16:09:45 2022 CET Tagged: no UserProperties: no Suspects: no Form: none JavaScript: no Pages: 7 Encrypted: no Page size: 595.26 x 779.52 pts Page rot: 0 File size: 208250 bytes Optimized: no PDF version: 1.6 name type encoding emb sub uni object ID ------------------------------------ ----------------- ---------------- --- --- --- --------- JJIILZ+HelveticaNeueLTStd-Bd Type 1C Custom yes yes no 36 0 MSGOBH+HelveticaNeueLTStd-Lt Type 1C Custom yes yes no 41 0 PIAOFJ+HelveticaNeueLTStd-BdIt Type 1C WinAnsi yes yes no 54 0 UQARXQ+HelveticaNeueLTStd-LtIt Type 1C Custom yes yes no 56 0 IMXEZC+HelveticaNeueLTStd-MdIt Type 1C WinAnsi yes yes no 61 0 MUTZMO+MTSY Type 1C Custom yes yes yes 63 0 VVNNRE+MinionPro-Regular Type 1C Custom yes yes no 71 0 OBAZBH+RMTMI Type 1C WinAnsi yes yes no 89 0 RRUUAU+MinionPro-It Type 1C WinAnsi yes yes no 104 0 HKXVPY+MinionPro-Bold Type 1C Custom yes yes no 107 0 Jhove (Rel. 1.22.1, 2019-04-17) Date: 2022-07-02 02:27:49 CEST RepresentationInformation: pmc_35083241.pdf ReportingModule: PDF-hul, Rel. 1.12.1 (2019-04-17) LastModified: 2022-01-31 03:32:32 CET Size: 208250 Format: PDF Version: 1.6 Status: Well-Formed and valid SignatureMatches: PDF-hul MIMEtype: application/pdf PDFMetadata: Objects: 228 FreeObjects: 12 IncrementalUpdates: 0 DocumentCatalog: ViewerPreferences: HideToolbar: false HideMenubar: false HideWindowUI: false FitWindow: true CenterWindow: false DisplayDocTitle: false NonFullScreenPageMode: UseNone Direction: L2R ViewArea: CropBox ViewClip: CropBox PrintArea: CropBox PageClip: CropBox PageLayout: SinglePage PageMode: UseOutlines Language: en Outlines: Item: Title: Cytokine Hemoadsorption as Rescue Therapy for Critically Ill Patients With SARS-CoV-2 Pneumonia With Severe Respiratory Failur攀 愀渀搀 䠀礀瀀攀爀挀礀琀漀欀椀渀攀洀椀愩㸾൥湤潢樍㘠〠潢樍㰼⽐慲敮琠㔠〠刯乥硴‷‰⁒⽄敳琯獥捴楯渪⸲⽁捴楯港䝯呯⽔楴汥⣾＀䤀渀琀爀漀搀甀挀琀椀漀温㸾൥湤潢樍㈸‰扪഼㰯偡牥湴‵‰⁒⽄敳琯獥捴楯渪⸲㐯䅣瑩潮⽇潔漯偲敶′㜠〠刯呩瑬攨References Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@76a3e297 Children: Item: Title: Introduction Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@4d3167f4 Item: Title: Methods Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@ed9d034 Children: Item: Title: Patients and Ethics Approval Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@6121c9d6 Item: Title: Inclusion and Exclusion Criteria Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@87f383f Item: Title: Analyzed Data and Scores Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@4eb7f003 Item: Title: CytoSorb® and Continuous Renal Replacement Therapy Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@eafc191 Item: Title: Measurement of Plasmatic Levels of Cytokines Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@612fc6eb Item: Title: Statistical Analysis Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@1060b431 Item: Title: Results Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@612679d6 Children: Item: Title: Characteristics of the Study Population Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@11758f2a Item: Title: Hemoadsorption Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@e720b71 Item: Title: Inflammatory Parameters and Organ Dysfunction Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@1b26f7b2 Item: Title: Discussion Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@491cc5c9 Children: Item: Title: Main Findings of This Study Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@74ad1f1f Item: Title: Previous Experience With Cytokine Hemoadsorption Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@6a1aab78 Item: Title: Characteristics of the Study Population. Target Patient Population Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@462d5aee Item: Title: Biomarker Levels and Organ Dysfunction Throughout Hemoadsorption in Relation to Outcomes Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@69b0fd6f Item: Title: Limitations Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@757942a1 Item: Title: Conclusions Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@4a87761d Item: Title: Data Availability Statement Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@66d1af89 Item: Title: Ethics Statement Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@8646db9 Item: Title: Author Contributions Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@37374a5e Item: Title: References Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@4671e53b Info: Title: Cytokine Hemoadsorption as Rescue Therapy for Critically Ill Patients With SARS-CoV-2 Pneumonia With Severe Respiratory Failure and Hypercytokinemia Author: Luis Chiscano-Camón Subject: Introduction: A dysregulated inflammatory response, known as ``cytokine storm'', plays an important role in the pathophysiology of coronavirus 2019 disease (COVID-19). 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