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Title:          Role of H4K16 acetylation in 53BP1 recruitment to double-strand break sites in in vitro aged cells
Subject:        Biogerontology, https://doi.org/10.1007/s10522-022-09979-6
Keywords:       H4K16 acetylation; 53BP1; In vitro aging; Double strand break repair; DNA damage
Author:         Lourdes González-Bermúdez 
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     Item: 
      Title: Role of H4K16 acetylation in 53BP1 recruitment to double-strand break sites in in vitro aged cells
      Children: 
       Item: 
        Title: Abstract 
       Item: 
        Title: Introduction
       Item: 
        Title: Methods
        Children: 
         Item: 
          Title: Cell culture and treatments
         Item: 
          Title: Cell cycle analysis by flow cytometry
         Item: 
          Title: Fluorescent immunodetection
         Item: 
          Title: Protein extraction and western blotting
         Item: 
          Title: RNA collection and RT-qPCR
         Item: 
          Title: Sh-RNA expressing plasmids
         Item: 
          Title: Lentivirus generation and infection
         Item: 
          Title: Statistical analysis
       Item: 
        Title: Results
        Children: 
         Item: 
          Title: Deficient 53BP1 recruitment to DSBs during in vitro aging correlates with diminished H4K16 acetylation
         Item: 
          Title: Differential H4K16 acetylation dynamics in early and late passage HDFs after DSBs induction
         Item: 
          Title: Increased 53BP1 recruitment after DSB induction in aged HDFs depends on a specific H4K16 acetylation level
         Item: 
          Title: MOF silencing alters 53BP1 recruitment to induced DSBs
       Item: 
        Title: Discussion
       Item: 
        Title: Conclusions
       Item: 
        Title: Acknowledgements 
       Item: 
        Title: References
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  Checksum: d9ed6696
   Type: CRC32
  Checksum: 21730c0f69135def1171f5dbb7ac49df
   Type: MD5
  Checksum: 524826e5ea8c419e46ba2b7abb302f99ab2b741f
   Type: SHA-1