da88975574623fc5caca29ea6e61d524 pmc_10025226.pdf e10bf4cafc726fa77e4b47cec4980475fa90334c pmc_10025226.pdf 588667712011b4b71c2c75d26d66563ba33d475ffafff53c52f735dd86b931fc pmc_10025226.pdf Title: A Phase I-II multicenter trial with Avelumab plus autologous dendritic cell vaccine in pre-treated mismatch repair-proficient (MSS) metastatic colorectal cancer patients; GEMCAD 1602 study Subject: Cancer Immunology, Immunotherapy, https://doi.org/10.1007/s00262-022-03283-5 Keywords: Vaccines; Metabolism; Resistance Author: Marta Español-Rego Creator: Springer Producer: Acrobat Distiller 10.1.8 (Windows) CreationDate: Thu Sep 8 00:26:12 2022 CEST ModDate: Sat Mar 11 11:59:54 2023 CET Tagged: no UserProperties: no Suspects: no Form: AcroForm JavaScript: no Pages: 14 Encrypted: no Page size: 595.276 x 790.866 pts Page rot: 0 File size: 3407983 bytes Optimized: yes PDF version: 1.4 name type encoding emb sub uni object ID ------------------------------------ ----------------- ---------------- --- --- --- --------- MyriadPro-SemiCn Type 1C WinAnsi yes no yes 318 0 MyriadPro-Semibold Type 1C Custom yes no yes 319 0 MyriadPro-SemiboldSemiCn Type 1C Custom yes no yes 320 0 MyriadPro-Bold Type 1C Custom yes no yes 321 0 MRPGRV+STIX-Regular Type 1C Custom yes yes yes 322 0 STIX-Italic Type 1C Custom yes no yes 343 0 LYILVK+Wingdings-Regular Type 1C WinAnsi yes yes yes 344 0 Springnew-Regular Type 1C WinAnsi yes no yes 352 0 MyriadPro-BoldSemiCn Type 1C Custom yes no yes 146 0 STIX-Bold Type 1C WinAnsi yes no yes 170 0 MyriadPro-SemiboldSemiCnIt Type 1C WinAnsi yes no yes 178 0 Jhove (Rel. 1.28.0, 2023-05-18) Date: 2024-02-09 02:30:27 CET RepresentationInformation: pmc_10025226.pdf ReportingModule: PDF-hul, Rel. 1.12.4 (2023-03-16) LastModified: 2023-07-28 02:24:42 CEST Size: 3407983 Format: PDF Version: 1.4 Status: Well-Formed and valid SignatureMatches: PDF-hul MIMEtype: application/pdf Profile: Linearized PDF PDFMetadata: Objects: 434 FreeObjects: 1 IncrementalUpdates: 1 DocumentCatalog: ViewerPreferences: HideToolbar: false HideMenubar: false HideWindowUI: false FitWindow: false CenterWindow: false DisplayDocTitle: false NonFullScreenPageMode: UseNone Direction: L2R ViewArea: CropBox ViewClip: CropBox PrintArea: CropBox PageClip: CropBox PageLayout: SinglePage PageMode: UseOutlines Language: EN Outlines: Item: Title: A Phase I-II multicenter trial with Avelumab plus autologous dendritic cell vaccine in pre-treated mismatch repair-proficient (MSS) metastatic colorectal cancer patients; GEMCAD 1602 study Children: Item: Title: Abstract Children: Item: Title: Background Item: Title: Methods Item: Title: Results Item: Title: Conclusions Item: Title: Introduction Item: Title: Methods Children: Item: Title: Study design Item: Title: Translational studies Children: Item: Title: Tumor specific T cell response Item: Title: Flow cytometry Item: Title: Cytokines Item: Title: RNA-seq: immune-metabolic signatures Item: Title: Efficacy assessments Item: Title: Statistical analysis Item: Title: Results Children: Item: Title: Patient characteristics Item: Title: Safety Item: Title: Efficacy Item: Title: Translational studies Children: Item: Title: In vitro study Item: Title: Cytokine monitoring Item: Title: Lymphocytic populations Item: Title: RNA immune-signatures Item: Title: Discussion Item: Title: Conclusion and perspective Item: Title: Anchor 28 Item: Title: Acknowledgements Item: Title: References Info: Title: A Phase I-II multicenter trial with Avelumab plus autologous dendritic cell vaccine in pre-treated mismatch repair-proficient (MSS) metastatic colorectal cancer patients; 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