65485f6e9c37f00aaefeaf1a5a898aca pmc_10108282.pdf a0ef9b110e370b1f42035c57cc2f5008063ac4a6 pmc_10108282.pdf df918c318dd55922511522d012607c364ccc9b4956e4ec70e12b36d8eb05783c pmc_10108282.pdf Title: De novo KCNA6 variants with attenuated KV1.6 channel deactivation in patients with epilepsy Creator: Adobe InDesign 15.1 (Windows) Producer: Adobe PDF Library 15.0 CreationDate: Sat Jan 21 05:51:28 2023 CET ModDate: Sat Jan 21 05:51:35 2023 CET Tagged: no UserProperties: no Suspects: no Form: none JavaScript: no Pages: 13 Encrypted: no Page size: 595.276 x 782.362 pts Page rot: 0 File size: 9555704 bytes Optimized: yes PDF version: 1.6 name type encoding emb sub uni object ID ------------------------------------ ----------------- ---------------- --- --- --- --------- QMTZFR+STIXTwoText-Italic Type 1C Custom yes yes yes 465 0 ECSATP+STIXTwoText Type 1C Custom yes yes yes 466 0 BQADDV+STIXTwoText-Bold Type 1C Custom yes yes yes 467 0 CCNJRT+STIXTwoText-BoldItalic Type 1C Custom yes yes yes 468 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with attenuated KV1.6 channel deactivation in patients with epilepsy Children: Item: Title: Abstract Item: Title: 1|INTRODUCTION Item: Title: 2|MATERIALS AND METHODS Children: Item: Title: 2.1|Consent and diagnosis Item: Title: 2.2|Next-­generation sequencing and bioinformatics Item: Title: 2.3|Homology model Item: Title: 2.4|Molecular biology and Xenopus laevis oocytes Item: Title: 2.5|Electrophysiology Item: Title: 3|RESULTS Children: Item: Title: 3.1|Clinical synopsis Item: Title: 3.2|Molecular genetic analysis and protein prediction Item: Title: 3.3|Electrophysiology studies Item: Title: 4|DISCUSSION Item: Title: 5|CONCLUSIONS Item: Title: AUTHOR CONTRIBUTIONS Item: Title: ACKNOWLEDGMENTS Item: Title: FUNDING INFORMATION Item: Title: CONFLICT OF INTEREST Item: Title: REFERENCES Info: Title: De novo KCNA6 variants with attenuated KV1.6 channel deactivation in patients with epilepsy Creator: Adobe InDesign 15.1 (Windows) Producer: Adobe PDF Library 15.0 CreationDate: Sat Jan 21 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