0108e8046ed6f60e640f136807529b40  pmc_10197276.pdf
a047389b83a296b8b9b7fe9f5902c122e2d57b28  pmc_10197276.pdf
69b0cace25af8784694c0f9d52216b0da0265981fa1f9a45d9ae22a71d1f67e0  pmc_10197276.pdf

Title:           Advances in Laboratory Medicine / Avances en Medicina de Laboratorio
Author:           YolandaVillena-Ortiz 
Creator:         
Producer:        Acrobat Distiller 20.0 (Windows)
CreationDate:    Tue Oct  4 07:30:59 2022 CEST
ModDate:         Tue Oct  4 07:31:34 2022 CEST
Custom Metadata: no
Metadata Stream: yes
Tagged:          no
UserProperties:  no
Suspects:        no
Form:            none
JavaScript:      no
Pages:           9
Encrypted:       no
Page size:       595.276 x 793.701 pts
Page rot:        0
File size:       547203 bytes
Optimized:       yes
PDF version:     1.7


name                                 type              encoding         emb sub uni object ID
------------------------------------ ----------------- ---------------- --- --- --- ---------
ANGGKN+AdvOT4f49f862                 Type 1C           WinAnsi          yes yes no     382  0
ANGGKO+AdvOT58b04b30.B               Type 1C           WinAnsi          yes yes no     384  0
ANGGKP+AdvOT15f0a2b2                 Type 1C           WinAnsi          yes yes no     386  0
ANGGMA+AdvOT15f0a2b2+fb              Type 1C           Custom           yes yes yes    393  0
ANGGMB+AdvOT15f0a2b2+20              Type 1C           WinAnsi          yes yes no     395  0
ANGGMC+AdvOT4f49f862+20              Type 1C           WinAnsi          yes yes no     399  0
ANGGMD+AdvOT310e2d14                 Type 1C           WinAnsi          yes yes no     401  0
ANGHDD+AdvOT310e2d14+22              Type 1C           Custom           yes yes no     168  0
ANGHCC+AdvOT15f0a2b2+03              Type 1C           Custom           yes yes yes    166  0
ANGHCD+AdvOT2df93c3e.I               Type 1C           WinAnsi          yes yes no     160  0
ANGHFD+AdvOT58b04b30.B+f1            Type 1C           Custom           yes yes yes    177  0
ANGHFE+AdvOT4f49f862+f1              Type 1C           Custom           yes yes yes    191  0
ANGHFF+AdvOT58b04b30.B+03            Type 1C           Custom           yes yes yes    186  0
ANGHFG+AdvOT4f49f862+03              Type 1C           Custom           yes yes yes    195  0
ANGHFH+AdvOT4f49f862+21              Type 1C           WinAnsi          yes yes no     171  0
ANGHFI+AdvOT4f49f862+fb              Type 1C           Custom           yes yes yes    174  0
ANGHII+AdvOT8019aa4f.BI              Type 1C           WinAnsi          yes yes no     200  0
ANGIAH+Arial-BoldMT                  TrueType          WinAnsi          yes yes no     206  0
ANGIHH+TimesNewRomanPS-BoldMT        TrueType          WinAnsi          yes yes no     215  0
ANGIHJ+TimesNewRomanPSMT             TrueType          WinAnsi          yes yes no     210  0
ANGIIK+ArialMT                       TrueType          WinAnsi          yes yes no     209  0


Jhove (Rel. 1.28.0, 2023-05-18)
 Date: 2024-04-18 02:41:41 CEST
 RepresentationInformation: pmc_10197276.pdf
  ReportingModule: PDF-hul, Rel. 1.12.4 (2023-03-16)
  LastModified: 2023-12-14 02:20:16 CET
  Size: 547203
  Format: PDF
  Version: 1.7
  Status: Well-Formed and valid
  SignatureMatches:
   PDF-hul
  MIMEtype: application/pdf
  Profile: Linearized PDF
  PDFMetadata: 
   Objects: 439
   FreeObjects: 1
   IncrementalUpdates: 1
   DocumentCatalog: 
    PageLayout: SinglePage
    PageMode: UseNone
    Outlines: 
     Item: 
      Title: Rapid and accurate method for quantifying busulfan in plasma samples by isocratic liquid chromatography-tandem mass spectro ...
      Destination: flink1
     Item: 
      Title: Introduction
      Destination: flink2
     Item: 
      Title: Materials and methods
      Destination: flink3
      Children: 
       Item: 
        Title: Reagents
        Destination: slink1
       Item: 
        Title: Equipment and conditions
        Destination: slink2
       Item: 
        Title: Sample preparation
        Destination: slink3
        Children: 
         Item: 
          Title: Stock solutions, calibration standards, and quality control samples
          Destination: tlink1
         Item: 
          Title: Sample pretreatment
          Destination: tlink2
       Item: 
        Title: Linearity
        Destination: slink4
       Item: 
        Title: Analytical sensitivity
        Destination: slink5
       Item: 
        Title: Accuracy and precision
        Destination: slink6
       Item: 
        Title: Selectivity and carryover
        Destination: slink7
       Item: 
        Title: Matrix effect, recovery, and process efficiency
        Destination: slink8
       Item: 
        Title: Stability assessments
        Destination: slink9
       Item: 
        Title: Clinical application
        Destination: slink10
     Item: 
      Title: Results
      Destination: flink4
      Children: 
       Item: 
        Title: Linearity
        Destination: slink11
       Item: 
        Title: Analytical sensitivity
        Destination: slink12
       Item: 
        Title: Accuracy and precision
        Destination: slink13
       Item: 
        Title: Selectivity and carryover
        Destination: slink14
       Item: 
        Title: ME, RE, and PE
        Destination: slink15
       Item: 
        Title: Stability
        Destination: slink16
       Item: 
        Title: Clinical application
        Destination: slink17
     Item: 
      Title: Discussion
      Destination: flink5
     Item: 
      Title: References
      Destination: flink6
   Info: 
    Title: Advances in Laboratory Medicine / Avances en Medicina de Laboratorio
    Author:  YolandaVillena-Ortiz 
    Creator: 
    Producer: Acrobat Distiller 20.0 (Windows)
    CreationDate: Tue Oct 04 08:00:59 CEST 2022
    ModDate: Tue Oct 04 08:01:34 CEST 2022
   ID: 0xd12b70b2819386abb0e8d9ff89cf8d9b, 0x46bbe39d82d7204fac48443ac60ede70
   Filters: 
    FilterPipeline: FlateDecode
   Fonts: 
    Type1: 
     Font: 
      BaseFont: ANGGKO+AdvOT58b04b30.B
      FontSubset: true
      FirstChar: 35
      LastChar: 243
      FontDescriptor: 
       FontName: ANGGKO+AdvOT58b04b30.B
       Flags: Serif, Nonsymbolic
       FontBBox: -31, -218, 968, 937
       FontFile3: true
      Encoding: WinAnsiEncoding
     Font: 
      BaseFont: ANGHCD+AdvOT2df93c3e.I
      FontSubset: true
      FirstChar: 101
      LastChar: 122
      FontDescriptor: 
       FontName: ANGHCD+AdvOT2df93c3e.I
       Flags: Nonsymbolic
       FontBBox: -93, -229, 947, 916
       FontFile3: true
      Encoding: WinAnsiEncoding
     Font: 
      BaseFont: ANGGKP+AdvOT15f0a2b2
      FontSubset: true
      FirstChar: 37
      LastChar: 241
      FontDescriptor: 
       FontName: ANGGKP+AdvOT15f0a2b2
       Flags: Serif, Nonsymbolic
       FontBBox: -31, -229, 895, 916
       FontFile3: true
      Encoding: WinAnsiEncoding
     Font: 
      BaseFont: ANGHFG+AdvOT4f49f862+03
      FontSubset: true
      FirstChar: 1
      LastChar: 1
      FontDescriptor: 
       FontName: ANGHFG+AdvOT4f49f862+03
       Flags: Symbolic
       FontBBox: -875, -364, 739, 916
       FontFile3: true
      EncodingDictionary: 
       Differences: true
      ToUnicode: true
     Font: 
      BaseFont: ANGHCC+AdvOT15f0a2b2+03
      FontSubset: true
      FirstChar: 1
      LastChar: 1
      FontDescriptor: 
       FontName: ANGHCC+AdvOT15f0a2b2+03
       Flags: Symbolic
       FontBBox: -875, -364, 802, 916
       FontFile3: true
      EncodingDictionary: 
       Differences: true
      ToUnicode: true
     Font: 
      BaseFont: ANGHDD+AdvOT310e2d14+22
      FontSubset: true
      FirstChar: 21
      LastChar: 21
      FontDescriptor: 
       FontName: ANGHDD+AdvOT310e2d14+22
       Flags: Nonsymbolic
       FontBBox: -135, -385, 1333, 895
       FontFile3: true
      EncodingDictionary: 
       BaseEncoding: WinAnsiEncoding
       Differences: true
     Font: 
      BaseFont: ANGHII+AdvOT8019aa4f.BI
      FontSubset: true
      FirstChar: 109
      LastChar: 122
      FontDescriptor: 
       FontName: ANGHII+AdvOT8019aa4f.BI
       Flags: Nonsymbolic
       FontBBox: -114, -239, 1062, 937
       FontFile3: true
      Encoding: WinAnsiEncoding
     Font: 
      BaseFont: ANGGMA+AdvOT15f0a2b2+fb
      FontSubset: true
      FirstChar: 1
      LastChar: 3
      FontDescriptor: 
       FontName: ANGGMA+AdvOT15f0a2b2+fb
       Flags: Symbolic
       FontBBox: 19, 0, 822, 729
       FontFile3: true
      EncodingDictionary: 
       Differences: true
      ToUnicode: true
     Font: 
      BaseFont: ANGGMB+AdvOT15f0a2b2+20
      FontSubset: true
      FirstChar: 146
      LastChar: 150
      FontDescriptor: 
       FontName: ANGGMB+AdvOT15f0a2b2+20
       Flags: Nonsymbolic
       FontBBox: -208, -281, 1604, 927
       FontFile3: true
      Encoding: WinAnsiEncoding
     Font: 
      BaseFont: ANGHFH+AdvOT4f49f862+21
      FontSubset: true
      FirstChar: 153
      LastChar: 153
      FontDescriptor: 
       FontName: ANGHFH+AdvOT4f49f862+21
       Flags: Nonsymbolic
       FontBBox: 0, -270, 1322, 854
       FontFile3: true
      Encoding: WinAnsiEncoding
     Font: 
      BaseFont: ANGHFI+AdvOT4f49f862+fb
      FontSubset: true
      FirstChar: 1
      LastChar: 3
      FontDescriptor: 
       FontName: ANGHFI+AdvOT4f49f862+fb
       Flags: Symbolic
       FontBBox: 40, 0, 812, 729
       FontFile3: true
      EncodingDictionary: 
       Differences: true
      ToUnicode: true
     Font: 
      BaseFont: ANGGMC+AdvOT4f49f862+20
      FontSubset: true
      FirstChar: 146
      LastChar: 150
      FontDescriptor: 
       FontName: ANGGMC+AdvOT4f49f862+20
       Flags: Nonsymbolic
       FontBBox: -208, -270, 1562, 927
       FontFile3: true
      Encoding: WinAnsiEncoding
     Font: 
      BaseFont: ANGGMD+AdvOT310e2d14
      FontSubset: true
      FirstChar: 43
      LastChar: 215
      FontDescriptor: 
       FontName: ANGGMD+AdvOT310e2d14
       Flags: Nonsymbolic
       FontBBox: -20, -427, 1541, 1062
       FontFile3: true
      Encoding: WinAnsiEncoding
     Font: 
      BaseFont: ANGHFD+AdvOT58b04b30.B+f1
      FontSubset: true
      FirstChar: 1
      LastChar: 4
      FontDescriptor: 
       FontName: ANGHFD+AdvOT58b04b30.B+f1
       Flags: Symbolic
       FontBBox: 19, -52, 541, 718
       FontFile3: true
      EncodingDictionary: 
       Differences: true
      ToUnicode: true
     Font: 
      BaseFont: ANGHFF+AdvOT58b04b30.B+03
      FontSubset: true
      FirstChar: 1
      LastChar: 1
      FontDescriptor: 
       FontName: ANGHFF+AdvOT58b04b30.B+03
       Flags: Symbolic
       FontBBox: -895, -375, 822, 927
       FontFile3: true
      EncodingDictionary: 
       Differences: true
      ToUnicode: true
     Font: 
      BaseFont: ANGGKN+AdvOT4f49f862
      FontSubset: true
      FirstChar: 37
      LastChar: 243
      FontDescriptor: 
       FontName: ANGGKN+AdvOT4f49f862
       Flags: Serif, Nonsymbolic
       FontBBox: -31, -208, 1000, 927
       FontFile3: true
      Encoding: WinAnsiEncoding
     Font: 
      BaseFont: ANGHFE+AdvOT4f49f862+f1
      FontSubset: true
      FirstChar: 1
      LastChar: 11
      FontDescriptor: 
       FontName: ANGHFE+AdvOT4f49f862+f1
       Flags: Symbolic
       FontBBox: 51, -41, 510, 697
       FontFile3: true
      EncodingDictionary: 
       Differences: true
      ToUnicode: true
    TrueType: 
     Font: 
      BaseFont: ANGIIK+ArialMT
      FontSubset: true
      FirstChar: 40
      LastChar: 117
      FontDescriptor: 
       FontName: ANGIIK+ArialMT
       Flags: Nonsymbolic
       FontBBox: -665, -325, 2000, 1040
       FontFile2: true
      Encoding: WinAnsiEncoding
     Font: 
      BaseFont: ANGIHJ+TimesNewRomanPSMT
      FontSubset: true
      FirstChar: 48
      LastChar: 121
      FontDescriptor: 
       FontName: ANGIHJ+TimesNewRomanPSMT
       Flags: Serif, Nonsymbolic
       FontBBox: -568, -307, 2046, 1040
       FontFile2: true
      Encoding: WinAnsiEncoding
     Font: 
      BaseFont: ANGIHH+TimesNewRomanPS-BoldMT
      FontSubset: true
      FirstChar: 37
      LastChar: 186
      FontDescriptor: 
       FontName: ANGIHH+TimesNewRomanPS-BoldMT
       Flags: Serif, Nonsymbolic
       FontBBox: -558, -328, 2000, 1056
       FontFile2: true
      Encoding: WinAnsiEncoding
     Font: 
      BaseFont: ANGIAH+Arial-BoldMT
      FontSubset: true
      FirstChar: 37
      LastChar: 174
      FontDescriptor: 
       FontName: ANGIAH+Arial-BoldMT
       Flags: Nonsymbolic
       FontBBox: -628, -376, 2000, 1056
       FontFile2: true
      Encoding: WinAnsiEncoding
   XMP: <x:xmpmeta xmlns:x="adobe:ns:meta/" x:xmptk="Adobe XMP Core 5.6-c017 91.164464, 2020/06/15-10:20:05        ">
   <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#">
      <rdf:Description rdf:about=""
            xmlns:xmp="http://ns.adobe.com/xap/1.0/"
            xmlns:dc="http://purl.org/dc/elements/1.1/"
            xmlns:dg="http://www.degruyter.com/ns//web-pdf/"
            xmlns:xmpRights="http://ns.adobe.com/xap/1.0/rights/"
            xmlns:pdfaid="http://www.aiim.org/pdfa/ns/id/"
            xmlns:illustrator="http://ns.adobe.com/illustrator/1.0/"
            xmlns:pdf="http://ns.adobe.com/pdf/1.3/"
            xmlns:xmpMM="http://ns.adobe.com/xap/1.0/mm/"
            xmlns:pdfaExtension="http://www.aiim.org/pdfa/ns/extension/"
            xmlns:pdfaSchema="http://www.aiim.org/pdfa/ns/schema#"
            xmlns:pdfaProperty="http://www.aiim.org/pdfa/ns/property#">
         <xmp:ModifyDate>2022-10-04T11:01:34+05:30</xmp:ModifyDate>
         <xmp:CreateDate>2022-10-04T11:00:59+05:30</xmp:CreateDate>
         <xmp:MetadataDate>2022-10-04T11:01:34+05:30</xmp:MetadataDate>
         <xmp:CreatorTool/>
         <dc:format>application/pdf</dc:format>
         <dc:title>
            <rdf:Alt>
               <rdf:li xml:lang="x-default">Advances in Laboratory Medicine / Avances en Medicina de Laboratorio</rdf:li>
            </rdf:Alt>
         </dc:title>
         <dc:rights>
            <rdf:Alt>
               <rdf:li xml:lang="x-default">© 2022 Yolanda Villena-Ortiz et al., published by De Gruyter, Berlin/Boston</rdf:li>
            </rdf:Alt>
         </dc:rights>
         <dc:creator>
            <rdf:Seq>
               <rdf:li> YolandaVillena-Ortiz </rdf:li>
            </rdf:Seq>
         </dc:creator>
         <dc:subject>
            <rdf:Bag>
               <rdf:li>hematopoietic stem cell transplantation</rdf:li>
               <rdf:li>mass spectrometry platform</rdf:li>
               <rdf:li>method validation</rdf:li>
               <rdf:li>therapeutic drug monitoring</rdf:li>
            </rdf:Bag>
         </dc:subject>
         <dg:DOI>10.1515/almed-2022-0016</dg:DOI>
         <dg:DOI-URL>https://doi.org/10.1515/almed-2022-0016</dg:DOI-URL>
         <xmpRights:Marked>True</xmpRights:Marked>
         <xmpRights:WebStatement>https://www.degruyter.com/page/terms-conditions?language=en</xmpRights:WebStatement>
         <pdfaid:conformance>B</pdfaid:conformance>
         <pdfaid:part>2</pdfaid:part>
         <illustrator:StartupProfile>Print</illustrator:StartupProfile>
         <pdf:Producer>Acrobat Distiller 20.0 (Windows)</pdf:Producer>
         <xmpMM:DocumentID>uuid:ebe99454-1f33-4700-a19b-da50fba29c2e</xmpMM:DocumentID>
         <xmpMM:InstanceID>uuid:23bc9074-71bd-44a2-b6e2-9154462e1bf8</xmpMM:InstanceID>
         <pdfaExtension:schemas>
            <rdf:Bag>
               <rdf:li rdf:parseType="Resource">
                  <pdfaSchema:schema>De Gruyter XMP Schema for WEB PDF</pdfaSchema:schema>
                  <pdfaSchema:namespaceURI>http://www.degruyter.com/ns//web-pdf/</pdfaSchema:namespaceURI>
                  <pdfaSchema:prefix>dg</pdfaSchema:prefix>
                  <pdfaSchema:property>
                     <rdf:Seq>
                        <rdf:li rdf:parseType="Resource">
                           <pdfaProperty:name>10.1515/almed-2022-0016</pdfaProperty:name>
                           <pdfaProperty:valueType>Text</pdfaProperty:valueType>
                           <pdfaProperty:category>external</pdfaProperty:category>
                           <pdfaProperty:description>The Digital Object Identifier of document</pdfaProperty:description>
                        </rdf:li>
                        <rdf:li rdf:parseType="Resource">
                           <pdfaProperty:name>https://doi.org/10.1515/almed-2022-0016</pdfaProperty:name>
                           <pdfaProperty:valueType>text</pdfaProperty:valueType>
                           <pdfaProperty:category>external</pdfaProperty:category>
                           <pdfaProperty:description>The corresponding URL of the Digital Object Identifier.</pdfaProperty:description>
                        </rdf:li>
                     </rdf:Seq>
                  </pdfaSchema:property>
               </rdf:li>
            </rdf:Bag>
         </pdfaExtension:schemas>
      </rdf:Description>
   </rdf:RDF>
</x:xmpmeta>
   Pages: 
    Page: 
     Label: 1
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 51, 540, 195, 548
      Annotation: 
       Subtype: Link
       Rect: 475, 105, 478, 115
       Destination: 118
      Annotation: 
       Subtype: Link
       Rect: 159, 253, 234, 261
      Annotation: 
       Subtype: Link
       Rect: 239, 253, 286, 261
      Annotation: 
       Subtype: Link
       Rect: 51, 242, 144, 250
      Annotation: 
       Subtype: Link
       Rect: 113, 132, 252, 140
     Thumb: true
    Page: 
     Label: 2
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 65, 712, 79, 722
       Destination: 118
      Annotation: 
       Subtype: Link
       Rect: 238, 687, 242, 696
       Destination: 118
      Annotation: 
       Subtype: Link
       Rect: 248, 687, 253, 696
       Destination: 118
      Annotation: 
       Subtype: Link
       Rect: 190, 648, 195, 657
       Destination: 118
      Annotation: 
       Subtype: Link
       Rect: 138, 622, 157, 631
       Destination: 118
      Annotation: 
       Subtype: Link
       Rect: 273, 583, 281, 592
       Destination: 118
      Annotation: 
       Subtype: Link
       Rect: 120, 531, 128, 541
       Destination: 118
      Annotation: 
       Subtype: Link
       Rect: 133, 531, 142, 541
       Destination: 118
      Annotation: 
       Subtype: Link
       Rect: 247, 518, 256, 528
       Destination: 118
      Annotation: 
       Subtype: Link
       Rect: 156, 505, 164, 515
       Destination: 118
      Annotation: 
       Subtype: Link
       Rect: 232, 479, 255, 489
       Destination: 118
      Annotation: 
       Subtype: Link
       Rect: 263, 479, 292, 489
       Destination: 27
      Annotation: 
       Subtype: Link
       Rect: 253, 441, 262, 450
       Destination: 129
      Annotation: 
       Subtype: Link
       Rect: 308, 637, 333, 645
       Destination: 45
      Annotation: 
       Subtype: Link
       Rect: 378, 177, 385, 185
       Destination: 129
      Annotation: 
       Subtype: Link
       Rect: 424, 65, 433, 73
       Destination: 129
      Annotation: 
       Subtype: Link
       Rect: 437, 65, 444, 73
       Destination: 129
     Thumb: true
    Page: 
     Label: 3
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 73, 630, 82, 638
       Destination: 118
      Annotation: 
       Subtype: Link
       Rect: 53, 543, 62, 550
       Destination: 129
      Annotation: 
       Subtype: Link
       Rect: 73, 477, 82, 485
       Destination: 129
      Annotation: 
       Subtype: Link
       Rect: 73, 422, 82, 430
       Destination: 129
      Annotation: 
       Subtype: Link
       Rect: 73, 378, 82, 386
       Destination: 129
      Annotation: 
       Subtype: Link
       Rect: 53, 291, 62, 298
       Destination: 129
      Annotation: 
       Subtype: Link
       Rect: 73, 269, 82, 277
       Destination: 129
      Annotation: 
       Subtype: Link
       Rect: 53, 214, 62, 222
       Destination: 129
      Annotation: 
       Subtype: Link
       Rect: 73, 170, 82, 178
       Destination: 129
     Thumb: true
    Page: 
     Label: 4
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 205, 535, 212, 543
       Destination: 129
      Annotation: 
       Subtype: Link
       Rect: 230, 491, 238, 499
       Destination: 129
      Annotation: 
       Subtype: Link
       Rect: 243, 491, 250, 499
       Destination: 129
      Annotation: 
       Subtype: Link
       Rect: 142, 185, 150, 193
       Destination: 129
      Annotation: 
       Subtype: Link
       Rect: 82, 98, 89, 106
       Destination: 129
      Annotation: 
       Subtype: Link
       Rect: 311, 423, 318, 431
       Destination: 129
      Annotation: 
       Subtype: Link
       Rect: 458, 230, 466, 238
       Destination: 129
      Annotation: 
       Subtype: Link
       Rect: 394, 219, 401, 227
       Destination: 129
      Annotation: 
       Subtype: Link
       Rect: 532, 219, 539, 227
       Destination: 129
      Annotation: 
       Subtype: Link
       Rect: 494, 186, 501, 194
       Destination: 129
     Thumb: true
    Page: 
     Label: 5
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 70, 659, 77, 667
       Destination: 129
      Annotation: 
       Subtype: Link
       Rect: 254, 467, 286, 476
       Destination: 369
      Annotation: 
       Subtype: Link
       Rect: 51, 454, 114, 463
       Destination: 369
      Annotation: 
       Subtype: Link
       Rect: 254, 377, 286, 386
       Destination: 1
      Annotation: 
       Subtype: Link
       Rect: 51, 364, 116, 373
       Destination: 1
      Annotation: 
       Subtype: Link
       Rect: 102, 157, 191, 167
       Destination: 369
      Annotation: 
       Subtype: Link
       Rect: 352, 574, 386, 583
       Destination: 82
      Annotation: 
       Subtype: Link
       Rect: 330, 433, 360, 442
       Destination: 82
      Annotation: 
       Subtype: Link
       Rect: 349, 285, 385, 295
       Destination: 96
     Thumb: true
    Page: 
     Label: 6
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 232, 91, 267, 101
       Destination: 96
     Thumb: true
    Page: 
     Label: 7
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 174, 540, 196, 550
       Destination: 118
      Annotation: 
       Subtype: Link
       Rect: 53, 514, 83, 524
       Destination: 27
      Annotation: 
       Subtype: Link
       Rect: 149, 463, 177, 472
       Destination: 27
      Annotation: 
       Subtype: Link
       Rect: 388, 437, 396, 447
       Destination: 129
      Annotation: 
       Subtype: Link
       Rect: 402, 437, 410, 447
       Destination: 129
     Thumb: true
    Page: 
     Label: 8
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 246, 609, 277, 618
       Destination: 82
      Annotation: 
       Subtype: Link
       Rect: 154, 596, 186, 605
       Destination: 96
     Thumb: true
    Page: 
     Label: 9
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 367, 615, 521, 623
      Annotation: 
       Subtype: Link
       Rect: 313, 604, 515, 612
      Annotation: 
       Subtype: Link
       Rect: 458, 539, 523, 547
      Annotation: 
       Subtype: Link
       Rect: 313, 528, 530, 536
      Annotation: 
       Subtype: Link
       Rect: 313, 517, 509, 525
      Annotation: 
       Subtype: Link
       Rect: 383, 297, 528, 305
      Annotation: 
       Subtype: Link
       Rect: 493, 265, 532, 273
      Annotation: 
       Subtype: Link
       Rect: 297, 254, 399, 262
     Thumb: true
  Checksum: ab1a7ef9
   Type: CRC32
  Checksum: 0108e8046ed6f60e640f136807529b40
   Type: MD5
  Checksum: a047389b83a296b8b9b7fe9f5902c122e2d57b28
   Type: SHA-1
  Checksum: 69b0cace25af8784694c0f9d52216b0da0265981fa1f9a45d9ae22a71d1f67e0
   Type: SHA-256