df875a94c42169831ab28a5cbc0bc226 pmc_35063018.pdf b6a876ab2cf6d6116af06f75db8fd1e6c8d9a153 pmc_35063018.pdf ff7244acdfde6845507985089323e4e73f69a42d8f91341050e6d298c510f5de pmc_35063018.pdf Title: Sustained low disease activity measured by ASDAS slow radiographic spinal progression in axial spondyloarthritis patients treated with TNF-inhibitors: data from REGISPONSERBIO Subject: Arthritis Research & Therapy, https://doi.org/10.1186/s13075-021-02695-5 Keywords: Spondyloarthritis;Radiology;Biological therapies;Inflammation;Outcome measures Author: Maria Llop Creator: Adobe InDesign 15.0 (Windows) Producer: Adobe PDF Library 15.0; modified using iText® 5.3.5 ©2000-2012 1T3XT BVBA (SPRINGER SBM; licensed version) CreationDate: Mon Jan 17 07:44:21 2022 CET ModDate: Fri Jan 21 10:27:01 2022 CET Tagged: no UserProperties: no Suspects: no Form: none JavaScript: no Pages: 9 Encrypted: no Page size: 595.276 x 790.866 pts Page rot: 0 File size: 981014 bytes Optimized: no PDF version: 1.4 name type encoding emb sub uni object ID ------------------------------------ ----------------- ---------------- --- --- --- --------- MyriadPro-Regular Type 1C Custom yes no yes 29 0 MyriadPro-Bold Type 1C WinAnsi yes no yes 32 0 MyriadPro-It Type 1C Custom yes no yes 31 0 WarnockPro-Regular Type 1C Custom yes no yes 30 0 MyriadPro-Semibold Type 1C Custom yes no yes 35 0 MyriadPro-Light Type 1C Custom yes no yes 34 0 PLLLPG+MyriadPro-LightIt Type 1C WinAnsi yes yes yes 111 0 JQXTMD+MTSY Type 1C Custom yes yes yes 33 0 MyriadPro-Regular2 Type 1C WinAnsi yes no yes 182 0 RMXQVM+WarnockPro-It Type 1C WinAnsi yes yes yes 79 0 WIUORO+MyriadPro-SemiboldIt Type 1C WinAnsi yes yes yes 90 0 MyriadPro-Regular3 Type 1C WinAnsi yes no yes 161 0 POMPSU+OpenSans-Light Type 1C Custom yes yes no 168 0 POMPSU+OpenSans-Extrabold Type 1C WinAnsi yes yes no 164 0 POMPSU+OregonLDOBookSinistral Type 1C WinAnsi yes yes no 174 0 POMPSU+OpenSans-Bold Type 1C WinAnsi yes yes no 171 0 Jhove (Rel. 1.22.1, 2019-04-17) Date: 2023-03-10 02:37:52 CET RepresentationInformation: pmc_35063018.pdf ReportingModule: PDF-hul, Rel. 1.12.1 (2019-04-17) LastModified: 2022-01-31 03:34:12 CET Size: 981014 Format: PDF Version: 1.4 Status: Well-Formed and valid SignatureMatches: PDF-hul MIMEtype: application/pdf PDFMetadata: Objects: 317 FreeObjects: 1 IncrementalUpdates: 0 DocumentCatalog: ViewerPreferences: HideToolbar: false HideMenubar: false HideWindowUI: false FitWindow: false CenterWindow: false DisplayDocTitle: false NonFullScreenPageMode: UseNone Direction: L2R ViewArea: CropBox ViewClip: CropBox PrintArea: CropBox PageClip: CropBox PageLayout: SinglePage PageMode: UseOutlines Language: en-US Outlines: Item: Title: Sustained low disease activity measured by ASDAS slow radiographic spinal progression in axial spondyloarthritis patients treated with TNF-inhibitors: data from REGISPONSERBIO Children: Item: Title: Abstract Children: Item: Title: Background: Item: Title: Methods: Item: Title: Results: Item: Title: Conclusions: Item: Title: Introduction Item: Title: Methods Children: Item: Title: Patients and study design Item: Title: Assessment of radiographic progression Item: Title: Disease activity Item: Title: Statistical analysis Item: Title: Results Item: Title: Discussion Item: Title: Conclusions Item: Title: Acknowledgements Item: Title: References Info: Title: Sustained low disease activity measured by ASDAS slow radiographic spinal progression in axial spondyloarthritis patients treated with TNF-inhibitors: data from REGISPONSERBIO Author: Maria Llop Subject: Arthritis Research & Therapy, https://doi.org/10.1186/s13075-021-02695-5 Keywords: Spondyloarthritis;Radiology;Biological therapies;Inflammation;Outcome measures Creator: Adobe InDesign 15.0 (Windows) Producer: Adobe PDF Library 15.0; modified using iText® 5.3.5 ©2000-2012 1T3XT BVBA (SPRINGER SBM; licensed version) CreationDate: Mon Jan 17 07:44:21 CET 2022 ModDate: Fri Jan 21 10:27:01 CET 2022 ID: 0x22b54bffe1b84dc5304a22a9cef924db, 0x8617e22b65914a62756fc64ee1c1652a Filters: FilterPipeline: FlateDecode FilterPipeline: DCTDecode Images: Image: NisoImageMetadata: FormatName: image/png ImageWidth: 39 ImageHeight: 39 BitsPerSample: 8 BitsPerSampleUnit: integer Filter: FlateDecode Intent: RelativeColorimetric Decode: 0, 255 Name: X Image: NisoImageMetadata: FormatName: image/png ImageWidth: 39 ImageHeight: 74 BitsPerSample: 8 BitsPerSampleUnit: integer Filter: FlateDecode Intent: RelativeColorimetric Decode: 0, 255 Name: X Image: NisoImageMetadata: FormatName: image/png ImageWidth: 81 ImageHeight: 84 BitsPerSample: 8 BitsPerSampleUnit: integer Filter: FlateDecode Intent: RelativeColorimetric Decode: 0, 255 Name: X Image: NisoImageMetadata: FormatName: image/png ImageWidth: 665 ImageHeight: 100 BitsPerSample: 8 BitsPerSampleUnit: integer Filter: FlateDecode Intent: RelativeColorimetric Decode: 0, 255 Name: X Image: NisoImageMetadata: FormatName: image/png ImageWidth: 39 ImageHeight: 76 BitsPerSample: 8 BitsPerSampleUnit: integer Filter: FlateDecode Intent: RelativeColorimetric Decode: 0, 255 Name: X Image: NisoImageMetadata: FormatName: image/png ImageWidth: 40 ImageHeight: 76 BitsPerSample: 8 BitsPerSampleUnit: integer Filter: FlateDecode Intent: RelativeColorimetric Decode: 0, 255 Name: X Image: NisoImageMetadata: FormatName: image/jpg CompressionScheme: JPEG ImageWidth: 1418 ImageHeight: 1042 ColorSpace: RGB BitsPerSample: 8 BitsPerSampleUnit: integer Intent: RelativeColorimetric Name: X Image: NisoImageMetadata: FormatName: image/jpg CompressionScheme: JPEG ImageWidth: 1946 ImageHeight: 694 ColorSpace: RGB BitsPerSample: 8 BitsPerSampleUnit: integer Intent: RelativeColorimetric Name: X Image: NisoImageMetadata: FormatName: image/png ImageWidth: 1100 ImageHeight: 90 ColorSpace: black is zero BitsPerSample: 1 BitsPerSampleUnit: integer Filter: FlateDecode Intent: RelativeColorimetric Name: X Fonts: Type1: Font: BaseFont: MyriadPro-Bold FirstChar: 0 LastChar: 255 FontDescriptor: FontName: MyriadPro-Bold Flags: Nonsymbolic FontBBox: -163, -250, 1256, 989 FontFile3: true Encoding: WinAnsiEncoding ToUnicode: true Font: BaseFont: JQXTMD+MTSY FontSubset: true FirstChar: 0 LastChar: 255 FontDescriptor: FontName: JQXTMD+MTSY Flags: Symbolic FontBBox: 0, -954, 1043, 796 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true ToUnicode: true Font: BaseFont: MyriadPro-Light FirstChar: 0 LastChar: 255 FontDescriptor: FontName: MyriadPro-Light Flags: Nonsymbolic FontBBox: -49, -250, 1046, 883 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true ToUnicode: true Font: BaseFont: MyriadPro-Semibold FirstChar: 0 LastChar: 255 FontDescriptor: FontName: MyriadPro-Semibold Flags: Nonsymbolic FontBBox: -161, -250, 1198, 972 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true ToUnicode: true Font: BaseFont: WIUORO+MyriadPro-SemiboldIt FontSubset: true FirstChar: 0 LastChar: 255 FontDescriptor: FontName: WIUORO+MyriadPro-SemiboldIt Flags: Nonsymbolic, Italic FontBBox: -193, -250, 1164, 972 FontFile3: true Encoding: WinAnsiEncoding ToUnicode: true Font: BaseFont: MyriadPro-Regular FirstChar: 0 LastChar: 255 FontDescriptor: FontName: MyriadPro-Regular Flags: Nonsymbolic FontBBox: -157, -250, 1126, 952 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true ToUnicode: true Font: BaseFont: WarnockPro-Regular FirstChar: 0 LastChar: 255 FontDescriptor: FontName: WarnockPro-Regular Flags: Serif, Nonsymbolic FontBBox: -177, -533, 1474, 950 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true ToUnicode: true Font: BaseFont: PLLLPG+MyriadPro-LightIt FontSubset: true FirstChar: 0 LastChar: 255 FontDescriptor: FontName: PLLLPG+MyriadPro-LightIt Flags: Nonsymbolic, Italic FontBBox: -121, -250, 1007, 863 FontFile3: true Encoding: WinAnsiEncoding ToUnicode: true Font: BaseFont: MyriadPro-It FirstChar: 0 LastChar: 255 FontDescriptor: FontName: MyriadPro-It Flags: Nonsymbolic, Italic FontBBox: -185, -250, 1090, 953 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true ToUnicode: true Font: BaseFont: RMXQVM+WarnockPro-It FontSubset: true FirstChar: 0 LastChar: 255 FontDescriptor: FontName: RMXQVM+WarnockPro-It Flags: Serif, Nonsymbolic, Italic FontBBox: -221, -533, 1474, 950 FontFile3: true Encoding: WinAnsiEncoding ToUnicode: true XMP: 2022-01-17T06:44:21 Adobe InDesign 15.0 (Windows) 2022-01-21T10:27:01+01:00 2022-01-21T10:27:01+01:00 Adobe PDF Library 15.0; modified using iText® 5.3.5 ©2000-2012 1T3XT BVBA (SPRINGER SBM; licensed version) Spondyloarthritis;Radiology;Biological therapies;Inflammation;Outcome measures False application/pdf https://doi.org/10.1186/s13075-021-02695-5 BioMed Central Arthritis Research & Therapy, https://doi.org/10.1186/s13075-021-02695-5 Spondyloarthritis Radiology Biological therapies Inflammation Outcome measures Sustained low disease activity measured by ASDAS slow radiographic spinal progression in axial spondyloarthritis patients treated with TNF-inhibitors: data from REGISPONSERBIO Maria Llop Mireia Moreno Victoria Navarro-Compán Xavier Juanola Eugenio de Miguel Raquel Almodóvar Eduardo Cuende Quintana Jesús Sanz Sanz Emma Beltrán M. Dolores Ruiz Montesinos Joan Calvet Antoni Berenguer-Llergo Jordi Gratacós Pedro Zarco Montejo Beatriz Joven Miriam Almirall Ma Cruz Fernandez Espartero Enrique Batlle Gualda Cristina Campos Eduardo Collantes Estevez Pilar Font Teresa Clavaguera Poch Luis F. Linares Ferrando Carlos Rodríguez Lozano Beatriz Yoldi 10.1186/s13075-021-02695-5 2010-04-23 true springer.com springerlink.com https://doi.org/10.1186/s13075-021-02695-5 10.1186/s13075-021-02695-5 1478-6362 journal Arthritis Research & Therapy The Author(s) 2010-04-23 true 10.1186/s13075-021-02695-5 noindex springer.com springerlink.com uuid:4d6e5a43-4fbc-4460-9510-3707a5885a5f uuid:bb7dd4ff-dfd8-4a51-962e-bb528bcbe3a6 default 1 converted uuid:4d6e5a43-4fbc-4460-9510-3707a5885a5f converted to PDF/A-2b pdfToolbox 2022-01-20T14:28:03Z 2 B Jordi Gratacós http://orcid.org/0000-0003-4007-4103 http://ns.adobe.com/pdfx/1.3/ pdfx Adobe Document Info PDF eXtension Schema external Mirrors crossmark:MajorVersionDate CrossmarkMajorVersionDate Text external Mirrors crossmark:CrossmarkDomainExclusive CrossmarkDomainExclusive Text internal Mirrors crossmark:DOI doi Text external Mirrors crossmark:CrosMarkDomains CrossMarkDomains seq Text internal A name object indicating whether the document has been modified to include trapping information robots Text internal ID of PDF/X standard GTS_PDFXVersion Text internal Conformance level of PDF/X standard GTS_PDFXConformance Text internal Company creating the PDF Company Text internal Date when document was last modified SourceModified Text http://crossref.org/crossmark/1.0/ crossmark Crossmark Schema internal Usual same as prism:doi DOI Text external The date when a publication was publishe. MajorVersionDate Text internal CrossmarkDomainExclusive CrossmarkDomainExclusive Text internal CrossMarkDomains CrossMarkDomains seq Text http://prismstandard.org/namespaces/basic/2.0/ prism Prism Schema external This element provides the url for an article or unit of content. The attribute platform is optionally allowed for situations in which multiple URLs must be specified. PRISM recommends that a subset of the PCV platform values, namely “mobile” and “web”, be used in conjunction with this element. NOTE: PRISM recommends against the use of the #other value allowed in the PRISM Platform controlled vocabulary. In lieu of using #other please reach out to the PRISM group at prism-wg@yahoogroups.com to request addition of your term to the Platform Controlled Vocabulary. url URI external The Digital Object Identifier for the article. The DOI may also be used as the dc:identifier. If used as a dc:identifier, the URI form should be captured, and the bare identifier should also be captured using prism:doi. If an alternate unique identifier is used as the required dc:identifier, then the DOI should be specified as a bare identifier within prism:doi only. If the URL associated with a DOI is to be specified, then prism:url may be used in conjunction with prism:doi in order to provide the service endpoint (i.e. the URL). doi Text external ISSN for an electronic version of the issue in which the resource occurs. Permits publishers to include a second ISSN, identifying an electronic version of the issue in which the resource occurs (therefore e(lectronic)Issn. If used, prism:eIssn MUST contain the ISSN of the electronic version. issn Text internal Volume number volume Text internal Issue number number Text internal Starting page startingPage Text internal Ending page endingPage Text external The aggregation type specifies the unit of aggregation for a content collection. Comment PRISM recommends that the PRISM Aggregation Type Controlled Vocabulary be used to provide values for this element. Note: PRISM recommends against the use of the #other value currently allowed in this controlled vocabulary. In lieu of using #other please reach out to the PRISM group at info@prismstandard.org to request addition of your term to the Aggregation Type Controlled Vocabulary. aggregationType Text external Title of the magazine, or other publication, in which a resource was/will be published. Typically this will be used to provide the name of the magazine an article appeared in as metadata for the article, along with information such as the article title, the publisher, volume, number, and cover date. Note: Publication name can be used to differentiate between a print magazine and the online version if the names are different such as “magazine” and “magazine.com.” publicationName Text external Copyright copyright Text http://ns.adobe.com/pdf/1.3/ pdf Adobe PDF Schema internal A name object indicating whether the document has been modified to include trapping information Trapped Text http://ns.adobe.com/xap/1.0/mm/ xmpMM XMP Media Management Schema internal UUID based identifier for specific incarnation of a document InstanceID URI internal The common identifier for all versions and renditions of a document. DocumentID URI internal The common identifier for all versions and renditions of a document. OriginalDocumentID URI internal A reference to the original document from which this one is derived. It is a minimal reference; missing components can be assumed to be unchanged. For example, a new version might only need to specify the instance ID and version number of the previous version, or a rendition might only need to specify the instance ID and rendition class of the original. DerivedFrom ResourceRef Identifies a portion of a document. This can be a position at which the document has been changed since the most recent event history (stEvt:changed). For a resource within an xmpMM:Ingredients list, the ResourceRef uses this type to identify both the portion of the containing document that refers to the resource, and the portion of the referenced resource that is referenced. http://ns.adobe.com/xap/1.0/sType/Part# stPart Part http://www.aiim.org/pdfa/ns/id/ pdfaid PDF/A ID Schema internal Part of PDF/A standard part Integer internal Amendment of PDF/A standard amd Text internal Conformance level of PDF/A standard conformance Text Springer Nature ORCID Schema http://springernature.com/ns/xmpExtensions/2.0/ sn authorInfo Bag AuthorInformation external Author information: contains the name of each author and his/her ORCiD (ORCiD: Open Researcher and Contributor ID). An ORCiD is a persistent identifier (a non-proprietary alphanumeric code) to uniquely identify scientific and other academic authors. AuthorInformation http://springernature.com/ns/xmpExtensions/2.0/authorInfo/ author Specifies the types of author information: name and ORCID of an author. name Text Gives the name of an author. orcid URI Gives the ORCID of an author. Pages: Page: Sequence: 1 Annotations: Annotation: Subtype: Link Rect: 427, 532, 439, 520 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 212, 66, 330, 58 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 486, 66, 530, 58 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 180, 58, 276, 50 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 396, 157, 401, 145 Flags: Print AppearanceDictionary: true Destination: 134 Annotation: Subtype: Link Rect: 507, 683, 540, 650 Flags: Print AppearanceDictionary: true Thumb: true Page: Sequence: 2 Annotations: Annotation: Subtype: Link Rect: 198, 668, 203, 656 Flags: Print AppearanceDictionary: true Destination: 134 Annotation: Subtype: Link Rect: 209, 596, 214, 584 Flags: Print AppearanceDictionary: true Destination: 134 Annotation: Subtype: Link Rect: 88, 512, 93, 500 Flags: Print AppearanceDictionary: true Destination: 134 Annotation: Subtype: Link Rect: 99, 512, 104, 500 Flags: Print AppearanceDictionary: true Destination: 134 Annotation: Subtype: Link Rect: 89, 476, 94, 464 Flags: Print AppearanceDictionary: true Destination: 134 Annotation: Subtype: Link Rect: 99, 476, 104, 464 Flags: Print AppearanceDictionary: true Destination: 134 Annotation: Subtype: Link Rect: 116, 440, 121, 428 Flags: Print AppearanceDictionary: true Destination: 134 Annotation: Subtype: Link Rect: 497, 668, 507, 656 Flags: Print AppearanceDictionary: true Destination: 134 Annotation: Subtype: Link Rect: 497, 632, 506, 620 Flags: Print AppearanceDictionary: true Destination: 134 Annotation: Subtype: Link Rect: 307, 464, 317, 452 Flags: Print AppearanceDictionary: true Destination: 134 Annotation: Subtype: Link Rect: 326, 416, 331, 404 Flags: Print AppearanceDictionary: true Destination: 3 Thumb: true Page: Sequence: 3 Annotations: Annotation: Subtype: Link Rect: 221, 704, 231, 692 Flags: Print AppearanceDictionary: true Destination: 134 Annotation: Subtype: Link Rect: 174, 548, 179, 536 Flags: Print AppearanceDictionary: true Destination: 134 Annotation: Subtype: Link Rect: 185, 548, 189, 536 Flags: Print AppearanceDictionary: true Destination: 134 Annotation: Subtype: Link Rect: 59, 428, 69, 416 Flags: Print AppearanceDictionary: true Destination: 134 Annotation: Subtype: Link Rect: 177, 284, 182, 272 Flags: Print AppearanceDictionary: true Destination: 134 Annotation: Subtype: Link Rect: 187, 284, 197, 272 Flags: Print AppearanceDictionary: true Destination: 134 Annotation: Subtype: Link Rect: 59, 212, 69, 200 Flags: Print AppearanceDictionary: true Destination: 147 Annotation: Subtype: Link Rect: 74, 212, 84, 200 Flags: Print AppearanceDictionary: true Destination: 147 Annotation: Subtype: Link Rect: 238, 104, 248, 92 Flags: Print AppearanceDictionary: true Destination: 147 Annotation: Subtype: Link Rect: 362, 572, 372, 560 Flags: Print AppearanceDictionary: true Destination: 147 Thumb: true Page: Sequence: 4 Annotations: Annotation: Subtype: Link Rect: 108, 513, 118, 500 Flags: Print AppearanceDictionary: true Destination: 147 Annotation: Subtype: Link Rect: 96, 332, 101, 320 Flags: Print AppearanceDictionary: true Destination: 80 Annotation: Subtype: Link Rect: 230, 332, 235, 320 Flags: Print AppearanceDictionary: true Destination: 134 Annotation: Subtype: Link Rect: 265, 332, 270, 320 Flags: Print AppearanceDictionary: true Destination: 134 Annotation: Subtype: Link Rect: 61, 296, 66, 284 Flags: Print AppearanceDictionary: true Destination: 134 Annotation: Subtype: Link Rect: 91, 296, 96, 284 Flags: Print AppearanceDictionary: true Destination: 134 Annotation: Subtype: Link Rect: 207, 248, 212, 236 Flags: Print AppearanceDictionary: true Destination: 80 Annotation: Subtype: Link Rect: 257, 140, 262, 128 Flags: Print AppearanceDictionary: true Destination: 134 Annotation: Subtype: Link Rect: 87, 116, 92, 104 Flags: Print AppearanceDictionary: true Destination: 134 Annotation: Subtype: Link Rect: 326, 633, 330, 620 Flags: Print AppearanceDictionary: true Destination: 94 Annotation: Subtype: Link Rect: 418, 561, 423, 542 Flags: Print AppearanceDictionary: true Destination: 94 Annotation: Subtype: Link Rect: 495, 537, 500, 524 Flags: Print AppearanceDictionary: true Destination: 94 Annotation: Subtype: Link Rect: 357, 477, 362, 464 Flags: Print AppearanceDictionary: true Destination: 94 Annotation: Subtype: Link Rect: 455, 429, 460, 416 Flags: Print AppearanceDictionary: true Destination: 134 Annotation: Subtype: Link Rect: 398, 381, 403, 362 Flags: Print AppearanceDictionary: true Destination: 94 Thumb: true Page: Sequence: 5 Annotations: Annotation: Subtype: Link Rect: 433, 133, 438, 121 Flags: Print AppearanceDictionary: true Destination: 94 Annotation: Subtype: Link Rect: 500, 85, 505, 73 Flags: Print AppearanceDictionary: true Destination: 134 Thumb: true Page: Sequence: 6 Annotations: Annotation: Subtype: Link Rect: 390, 395, 395, 383 Flags: Print AppearanceDictionary: true Destination: 134 Annotation: Subtype: Link Rect: 400, 395, 405, 383 Flags: Print AppearanceDictionary: true Destination: 134 Annotation: Subtype: Link Rect: 410, 395, 420, 383 Flags: Print AppearanceDictionary: true Destination: 147 Annotation: Subtype: Link Rect: 511, 383, 516, 371 Flags: Print AppearanceDictionary: true Destination: 134 Annotation: Subtype: Link Rect: 522, 383, 533, 371 Flags: Print AppearanceDictionary: true Destination: 147 Annotation: Subtype: Link Rect: 454, 299, 459, 287 Flags: Print AppearanceDictionary: true Destination: 134 Annotation: Subtype: Link Rect: 416, 83, 421, 71 Flags: Print AppearanceDictionary: true Destination: 134 Annotation: Subtype: Link Rect: 425, 83, 436, 71 Flags: Print AppearanceDictionary: true Destination: 147 Thumb: true Page: Sequence: 7 Annotations: Annotation: Subtype: Link Rect: 278, 657, 288, 644 Flags: Print AppearanceDictionary: true Destination: 134 Annotation: Subtype: Link Rect: 56, 645, 66, 632 Flags: Print AppearanceDictionary: true Destination: 147 Annotation: Subtype: Link Rect: 231, 633, 236, 620 Flags: Print AppearanceDictionary: true Destination: 134 Annotation: Subtype: Link Rect: 178, 561, 188, 548 Flags: Print AppearanceDictionary: true Destination: 147 Annotation: Subtype: Link Rect: 193, 561, 203, 548 Flags: Print AppearanceDictionary: true Destination: 147 Annotation: Subtype: Link Rect: 154, 393, 164, 374 Flags: Print AppearanceDictionary: true Destination: 147 Annotation: Subtype: Link Rect: 170, 393, 180, 374 Flags: Print AppearanceDictionary: true Destination: 147 Annotation: Subtype: Link Rect: 205, 381, 215, 368 Flags: Print AppearanceDictionary: true Destination: 134 Annotation: Subtype: Link Rect: 203, 333, 208, 320 Flags: Print AppearanceDictionary: true Destination: 134 Annotation: Subtype: Link Rect: 215, 333, 225, 320 Flags: Print AppearanceDictionary: true Destination: 147 Annotation: Subtype: Link Rect: 180, 297, 190, 284 Flags: Print AppearanceDictionary: true Destination: 147 Annotation: Subtype: Link Rect: 233, 249, 242, 236 Flags: Print AppearanceDictionary: true Destination: 147 Annotation: Subtype: Link Rect: 418, 681, 428, 668 Flags: Print AppearanceDictionary: true Destination: 147 Annotation: Subtype: Link Rect: 355, 465, 365, 452 Flags: Print AppearanceDictionary: true Destination: 147 Thumb: true Page: Sequence: 8 Annotations: Annotation: Subtype: Link Rect: 248, 689, 281, 681 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 56, 680, 156, 672 Flags: Print AppearanceDictionary: true Thumb: true Page: Sequence: 9 Annotations: Annotation: Subtype: Link Rect: 249, 523, 272, 515 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 71, 514, 130, 506 Flags: Print AppearanceDictionary: true Thumb: true Checksum: f1f6dec6 Type: CRC32 Checksum: df875a94c42169831ab28a5cbc0bc226 Type: MD5 Checksum: b6a876ab2cf6d6116af06f75db8fd1e6c8d9a153 Type: SHA-1