ac9c04f89443c57597fcb86cabd1d70a pmc_35108125.pdf 99b969d27234ea610f41e9854563c7891bfba398 pmc_35108125.pdf f759977225d6dce65cb1fa8f938cd2a5be8a95b73ef4a69f4368c3c999fa00eb pmc_35108125.pdf Title: CATH1074348 1..11 Creator: Arbortext Advanced Print Publisher 10.0.1465/W Unicode Producer: Acrobat Distiller 8.1.0 (Windows) CreationDate: Tue Feb 1 15:49:55 2022 CET ModDate: Tue Feb 1 15:49:55 2022 CET Tagged: no UserProperties: no Suspects: no Form: none JavaScript: no Pages: 11 Encrypted: no Page size: 585.014 x 782.986 pts Page rot: 0 File size: 659641 bytes Optimized: yes PDF version: 1.4 name type encoding emb sub uni object ID ------------------------------------ ----------------- ---------------- --- --- --- --------- JIFBHF+AdvOTab3e3698.B Type 1C WinAnsi yes yes no 269 0 JIFBHG+AdvOTab3e3698.B+fb Type 1C Custom yes yes yes 270 0 JIFBIH+AdvOT896b6dae Type 1C WinAnsi yes yes no 271 0 JIFBII+AdvOT896b6dae+fb Type 1C Custom yes yes yes 272 0 JIFBIJ+AdvOT8608a8d1 Type 1C WinAnsi yes yes no 285 0 JIFBIK+AdvOT896b6dae+20 Type 1C WinAnsi yes yes no 288 0 JIFBJL+AdvOT29dffb6a.I Type 1C WinAnsi yes yes no 294 0 JIFBLL+AdvOT833fb896 Type 1C WinAnsi yes yes no 89 0 JIFBLM+AdvOT833fb896+fb Type 1C Custom yes yes yes 92 0 JIFBLN+AdvOT8608a8d1+20 Type 1C WinAnsi yes yes no 94 0 JIFBMN+AdvOT29dffb6a.I+fb Type 1C Custom yes yes yes 100 0 JIFEFP+AdvOT2ea83e65.I Type 1C WinAnsi yes yes no 103 0 Jhove (Rel. 1.22.1, 2019-04-17) Date: 2022-02-16 02:26:43 CET RepresentationInformation: pmc_35108125.pdf ReportingModule: PDF-hul, Rel. 1.12.1 (2019-04-17) LastModified: 2022-02-07 03:33:38 CET Size: 659641 Format: PDF Version: 1.4 Status: Well-Formed and valid SignatureMatches: PDF-hul MIMEtype: application/pdf Profile: Linearized PDF PDFMetadata: Objects: 315 FreeObjects: 1 IncrementalUpdates: 1 DocumentCatalog: PageLayout: SinglePage PageMode: UseNone Outlines: Item: Title: Introduction Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@ed9d034 Item: Title: Materials and Methods Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@6121c9d6 Children: Item: Title: Study Design Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@87f383f Item: Title: Study Drug Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@4eb7f003 Item: Title: Patients Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@eafc191 Item: Title: Data Collection Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@612fc6eb Item: Title: Efficacy Assessment Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@1060b431 Item: Title: Safety Assessment Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@612679d6 Item: Title: Sample Size Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@11758f2a Item: Title: Statistical Analysis Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@e720b71 Item: Title: Results Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@1b26f7b2 Children: Item: Title: Baseline Patient Characteristics and Disease Activity Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@491cc5c9 Item: Title: Bleeding Episodes Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@74ad1f1f Item: Title: Prevention of Surgical Bleeding Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@6a1aab78 Item: Title: Efficacy Assessment on Secondary Long-Term Prophylaxis Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@462d5aee Item: Title: Safety Assessment Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@69b0fd6f Item: Title: Discussion Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@757942a1 Item: Title: Conclusion Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@4a87761d Item: Title: Acknowledgements Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@66d1af89 Item: Title: References Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@8646db9 Info: Title: CATH1074348 1..11 Creator: Arbortext Advanced Print Publisher 10.0.1465/W Unicode Producer: Acrobat Distiller 8.1.0 (Windows) CreationDate: Tue Feb 01 16:19:55 CET 2022 ModDate: Tue Feb 01 16:19:55 CET 2022 ID: 0xfd83a12e3f70601edb267da713907f60, 0x0789e943af226145ab297c8a8fd9e451 Filters: FilterPipeline: FlateDecode Images: Image: NisoImageMetadata: FormatName: image/png ImageWidth: 1505 ImageHeight: 1299 ColorSpace: black is zero BitsPerSample: 8 BitsPerSampleUnit: integer Filter: FlateDecode Image: NisoImageMetadata: FormatName: image/png ImageWidth: 1950 ImageHeight: 534 ColorSpace: RGB BitsPerSample: 8 BitsPerSampleUnit: integer Filter: FlateDecode Fonts: Type1: Font: BaseFont: JIFBIK+AdvOT896b6dae+20 FontSubset: true FirstChar: 146 LastChar: 150 FontDescriptor: FontName: JIFBIK+AdvOT896b6dae+20 Flags: Nonsymbolic FontBBox: -156, -229, 1000, 687 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: JIFBII+AdvOT896b6dae+fb FontSubset: true FirstChar: 1 LastChar: 1 FontDescriptor: FontName: JIFBII+AdvOT896b6dae+fb Flags: Symbolic FontBBox: 0, 0, 687, 687 FontFile3: true EncodingDictionary: Differences: true ToUnicode: true Font: BaseFont: JIFBMN+AdvOT29dffb6a.I+fb FontSubset: true FirstChar: 1 LastChar: 1 FontDescriptor: FontName: JIFBMN+AdvOT29dffb6a.I+fb Flags: Symbolic FontBBox: 9, -187, 729, 687 FontFile3: true EncodingDictionary: Differences: true ToUnicode: true Font: BaseFont: JIFBJL+AdvOT29dffb6a.I FontSubset: true FirstChar: 37 LastChar: 233 FontDescriptor: FontName: JIFBJL+AdvOT29dffb6a.I Flags: Nonsymbolic FontBBox: -125, -229, 979, 927 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: JIFEFP+AdvOT2ea83e65.I FontSubset: true FirstChar: 65 LastChar: 121 FontDescriptor: FontName: JIFEFP+AdvOT2ea83e65.I Flags: Nonsymbolic FontBBox: -166, -208, 937, 864 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: JIFBLL+AdvOT833fb896 FontSubset: true FirstChar: 37 LastChar: 250 FontDescriptor: FontName: JIFBLL+AdvOT833fb896 Flags: Serif, Nonsymbolic FontBBox: -72, -208, 927, 875 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: JIFBLM+AdvOT833fb896+fb FontSubset: true FirstChar: 1 LastChar: 3 FontDescriptor: FontName: JIFBLM+AdvOT833fb896+fb Flags: Symbolic FontBBox: 9, 0, 812, 687 FontFile3: true EncodingDictionary: Differences: true ToUnicode: true Font: BaseFont: JIFBHF+AdvOTab3e3698.B FontSubset: true FirstChar: 44 LastChar: 250 FontDescriptor: FontName: JIFBHF+AdvOTab3e3698.B Flags: Nonsymbolic FontBBox: -52, -229, 1166, 947 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: JIFBIJ+AdvOT8608a8d1 FontSubset: true FirstChar: 61 LastChar: 61 FontDescriptor: FontName: JIFBIJ+AdvOT8608a8d1 Flags: Nonsymbolic FontBBox: -62, -208, 927, 958 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: JIFBHG+AdvOTab3e3698.B+fb FontSubset: true FirstChar: 1 LastChar: 3 FontDescriptor: FontName: JIFBHG+AdvOTab3e3698.B+fb Flags: Symbolic FontBBox: 0, 0, 833, 687 FontFile3: true EncodingDictionary: Differences: true ToUnicode: true Font: BaseFont: JIFBLN+AdvOT8608a8d1+20 FontSubset: true FirstChar: 146 LastChar: 150 FontDescriptor: FontName: JIFBLN+AdvOT8608a8d1+20 Flags: Nonsymbolic FontBBox: -968, -333, 2000, 1020 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: JIFBIH+AdvOT896b6dae FontSubset: true FirstChar: 37 LastChar: 243 FontDescriptor: FontName: JIFBIH+AdvOT896b6dae Flags: Nonsymbolic FontBBox: -52, -229, 1031, 927 FontFile3: true Encoding: WinAnsiEncoding XMP: Acrobat Distiller 8.1.0 (Windows) Arbortext Advanced Print Publisher 10.0.1465/W Unicode 2022-02-01T20:19:55+05:30 2022-02-01T20:19:55+05:30 application/pdf CATH1074348 1..11 uuid:8aee6a95-5384-4243-a3f2-9ee24a7849b8 uuid:edd29126-4b21-4d35-b6d0-49583dd5991a Pages: Page: Label: 1 Annotations: Annotation: Subtype: Link Rect: 321, 79, 413, 87 Annotation: Subtype: Link Rect: 235, 48, 508, 56 Annotation: Subtype: Link Rect: 36, 39, 536, 46 Annotation: Subtype: Link Rect: 36, 28, 233, 36 Annotation: Subtype: Link Rect: 442, 677, 538, 684 Annotation: Subtype: Link Rect: 459, 668, 543, 675 Annotation: Subtype: Link Rect: 442, 660, 530, 667 Page: Label: 2 Page: Label: 3 Page: Label: 4 Page: Label: 5 Page: Label: 6 Page: Label: 7 Page: Label: 8 Page: Label: 9 Page: Label: 10 Annotations: Annotation: Subtype: Link Rect: 182, 613, 275, 622 Annotation: Subtype: Link Rect: 248, 540, 285, 549 Annotation: Subtype: Link Rect: 50, 528, 71, 537 Annotation: Subtype: Link Rect: 50, 528, 140, 537 Annotation: Subtype: Link Rect: 175, 480, 214, 489 Annotation: Subtype: Link Rect: 175, 480, 234, 489 Annotation: Subtype: Link Rect: 175, 480, 266, 489 Annotation: Subtype: Link Rect: 114, 431, 164, 440 Annotation: Subtype: Link Rect: 114, 431, 176, 440 Annotation: Subtype: Link Rect: 114, 431, 194, 440 Annotation: Subtype: Link Rect: 161, 383, 199, 392 Annotation: Subtype: Link Rect: 161, 383, 220, 392 Annotation: Subtype: Link Rect: 161, 383, 252, 392 Annotation: Subtype: Link Rect: 143, 334, 212, 343 Annotation: Subtype: Link Rect: 218, 298, 285, 307 Annotation: Subtype: Link Rect: 50, 286, 97, 295 Annotation: Subtype: Link Rect: 66, 237, 139, 246 Annotation: Subtype: Link Rect: 66, 237, 148, 246 Annotation: Subtype: Link Rect: 66, 177, 124, 186 Annotation: Subtype: Link Rect: 66, 177, 193, 186 Annotation: Subtype: Link Rect: 248, 140, 285, 149 Annotation: Subtype: Link Rect: 50, 128, 71, 137 Annotation: Subtype: Link Rect: 50, 128, 140, 137 Annotation: Subtype: Link Rect: 141, 79, 197, 88 Annotation: Subtype: Link Rect: 141, 79, 265, 88 Annotation: Subtype: Link Rect: 121, 42, 213, 51 Annotation: Subtype: Link Rect: 536, 667, 548, 676 Annotation: Subtype: Link Rect: 313, 655, 423, 664 Annotation: Subtype: Link Rect: 402, 594, 459, 603 Annotation: Subtype: Link Rect: 402, 594, 529, 603 Annotation: Subtype: Link Rect: 402, 533, 456, 542 Annotation: Subtype: Link Rect: 402, 533, 522, 542 Annotation: Subtype: Link Rect: 375, 472, 431, 481 Annotation: Subtype: Link Rect: 375, 472, 499, 481 Annotation: Subtype: Link Rect: 313, 411, 386, 420 Annotation: Subtype: Link Rect: 313, 411, 395, 420 Annotation: Subtype: Link Rect: 516, 276, 548, 285 Annotation: Subtype: Link Rect: 313, 264, 336, 273 Annotation: Subtype: Link Rect: 313, 264, 357, 273 Annotation: Subtype: Link Rect: 313, 264, 369, 273 Annotation: Subtype: Link Rect: 313, 264, 396, 273 Annotation: Subtype: Link Rect: 511, 227, 548, 236 Annotation: Subtype: Link Rect: 313, 215, 334, 224 Annotation: Subtype: Link Rect: 313, 215, 403, 224 Annotation: Subtype: Link Rect: 392, 178, 507, 187 Annotation: Subtype: Link Rect: 516, 142, 548, 151 Annotation: Subtype: Link Rect: 313, 130, 413, 139 Annotation: Subtype: Link Rect: 421, 105, 478, 114 Annotation: Subtype: Link Rect: 421, 105, 548, 114 Annotation: Subtype: Link Rect: 348, 68, 414, 77 Annotation: Subtype: Link Rect: 433, 43, 545, 52 Page: Label: 11 Annotations: Annotation: Subtype: Link Rect: 139, 679, 250, 688 Annotation: Subtype: Link Rect: 160, 655, 250, 664 Annotation: Subtype: Link Rect: 473, 643, 530, 652 Annotation: Subtype: Link Rect: 473, 643, 550, 652 Annotation: Subtype: Link Rect: 316, 631, 365, 640 Checksum: 39cca12c Type: CRC32 Checksum: ac9c04f89443c57597fcb86cabd1d70a Type: MD5 Checksum: 99b969d27234ea610f41e9854563c7891bfba398 Type: SHA-1