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indirect destination - referenced object 'B57' cannot be found Offset: 5076918 ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - referenced object 'B58' cannot be found Offset: 5076918 MIMEtype: application/pdf PDFMetadata: Objects: 671 FreeObjects: 2 IncrementalUpdates: 2 DocumentCatalog: PageLayout: SinglePage PageMode: UseOutlines Outlines: Item: Title: Pleiotropic Effect of IL-6 Produced by B-Lymphocytes During Early Phases of Adaptive Immune Responses Against TB Infection Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@6121c9d6 Children: Item: Title: Introduction Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@87f383f Item: Title: Materials and Methods Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@4eb7f003 Children: Item: Title: Mice Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@eafc191 Item: Title: Infection Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@612fc6eb Item: Title: CFU Counts and Survival Time Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@1060b431 Item: Title: Lung Cell Suspensions Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@612679d6 Item: Title: Flow Cytometry Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@11758f2a Item: Title: Lung Pathology and Immunohistochemistry Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@e720b71 Item: Title: RNA Purification, cDNA Synthesis and Gene Expression Evaluation Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@1b26f7b2 Item: Title: Results Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@491cc5c9 Children: Item: Title: Both Systemic and Conditioned Deficiency in IL-6 Production Increases Severity of TB Infection Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@74ad1f1f Item: Title: IL-6 Deficiency in B Cells Alters the Early Mycobacteria-Specific Response of CD4+ T Cells Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@6a1aab78 Item: Title: B Cells Are an Important Source of IL-6 in the Lungs Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@462d5aee Item: Title: B-Cell-Specific IL-6 Deficiency and Lung Pathology Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@69b0fd6f Item: Title: Macrophage Polarization Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@757942a1 Item: Title: Discussion Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@4a87761d Item: Title: Data Availability Statement Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@66d1af89 Item: Title: Ethics Statement Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@8646db9 Item: Title: Author Contributions Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@37374a5e Item: Title: Funding Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@4671e53b Item: Title: Acknowledgments Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@2db7a79b Item: Title: Supplementary Material Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@6950e31 Item: Title: References Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@b7dd107 Info: Title: Pleiotropic Effect of IL-6 Produced by B-Lymphocytes During Early Phases of Adaptive Immune Responses Against TB Infection Author: Irina Linge Subject: The role of B cells migrating to the lung and forming follicles during tuberculosis (TB) inflammation is still the subject of debate Keywords: tuberculosis, B-cells, IL-6, lung inflammation, T cells Creator: Arbortext Advanced Print Publisher 10.0.1306/W Unicode Producer: Acrobat Distiller 7.0 (Windows) CreationDate: Sat Jan 22 05:59:53 CET 2022 ModDate: Sat Jan 22 06:15:24 CET 2022 ID: 0xfdd59fd701a019d6467bc8c5aa3d1143, 0x8e781d635f29e749aba7354afe34accc 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inflammation, T cells 2022-01-22T13:15:24+08:00 2022-01-22T12:59:53+08:00 Arbortext Advanced Print Publisher 10.0.1306/W Unicode 2022-01-22T13:15:24+08:00 application/pdf Pleiotropic Effect of IL-6 Produced by B-Lymphocytes During Early Phases of Adaptive Immune Responses Against TB Infection Irina Linge Anastasiya Tsareva Elena Kondratieva Alexander Dyatlov Juan Hidalgo Ruslan Zvartsev Alexander Apt The role of B cells migrating to the lung and forming follicles during tuberculosis (TB) inflammation is still the subject of debate tuberculosis B-cells IL-6 lung inflammation T cells uuid:d67c0fc0-c803-4611-bb21-83b62b913a62 uuid:e9f389a3-98d0-4bff-ba15-9ca67003648c Pages: Page: Label: 1 Annotations: Annotation: Subtype: Link Rect: 175, 607, 525, 628 Annotation: Subtype: Link Rect: 175, 584, 489, 605 Annotation: Subtype: Link Rect: 175, 561, 453, 582 Annotation: Subtype: Link Rect: 175, 538, 493, 559 Annotation: Subtype: Link Rect: 323, 98, 328, 108 Destination: 268 Annotation: Subtype: 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