5f6a1e5b1721f22337e3445b8f959121 pmc_8904462.pdf 82d17852447cdddf1d83de0e11176cfd13f28473 pmc_8904462.pdf f63f074f146755c95e27e2a1f1c556fd0435bf7bb59cd77d69a66955056032b7 pmc_8904462.pdf Title: Divergence time estimation using ddRAD data and an isolation-with-migration model applied to water vole populations of Arvicola Subject: Scientific Reports, https://doi.org/10.1038/s41598-022-07877-y Author: Alfonso Balmori-de la Puente Creator: Springer Producer: Adobe PDF Library 15.0; modified using iText® 5.3.5 ©2000-2012 1T3XT BVBA (SPRINGER SBM; licensed version) CreationDate: Tue Mar 8 09:23:47 2022 CET ModDate: Tue Mar 8 10:21:05 2022 CET Tagged: no UserProperties: no Suspects: no Form: none JavaScript: no Pages: 11 Encrypted: no Page size: 595.276 x 782.362 pts Page rot: 0 File size: 1568358 bytes Optimized: no PDF version: 1.6 name type encoding emb sub uni object ID ------------------------------------ ----------------- ---------------- --- --- --- --------- WXWDNF+Wingdings-Regular Type 1C WinAnsi yes yes yes 630 0 MinionPro-Regular Type 1C Custom yes no yes 75 0 Corbel-BoldItalic TrueType WinAnsi yes no yes 285 0 AEQBKT+Corbel-Bold CID TrueType Identity-H yes yes yes 77 0 Corbel2 TrueType WinAnsi yes no yes 78 0 QEYDAN+Corbel CID TrueType Identity-H yes yes yes 79 0 Corbel3 CID TrueType Identity-H yes no yes 667 0 Corbel4 TrueType WinAnsi yes no yes 494 0 MinionPro-It Type 1C Custom yes no yes 76 0 XARVPZ+ArialMT Type 1C WinAnsi yes yes no 102 0 TANZLH+Arial-BoldMT Type 1C WinAnsi yes yes no 103 0 MinionPro-Bold Type 1C Custom yes no yes 104 0 XARVPZ+Arial-ItalicMT Type 1C WinAnsi yes yes no 105 0 ArialMT2 Type 1C Custom yes no no 106 0 TANZLH+Code2000 CID TrueType Identity-H yes yes yes 184 0 ArialMT3 Type 1C WinAnsi yes no no 214 0 QOACVN+TimesNewRomanPSMT TrueType WinAnsi yes yes yes 360 0 Jhove (Rel. 1.22.1, 2019-04-17) Date: 2023-06-03 02:29:58 CEST RepresentationInformation: pmc_8904462.pdf ReportingModule: PDF-hul, Rel. 1.12.1 (2019-04-17) LastModified: 2022-03-28 07:25:34 CEST Size: 1568358 Format: PDF Version: 1.6 Status: Well-Formed and valid SignatureMatches: PDF-hul MIMEtype: application/pdf PDFMetadata: Objects: 709 FreeObjects: 1 IncrementalUpdates: 0 DocumentCatalog: ViewerPreferences: HideToolbar: false HideMenubar: false HideWindowUI: false FitWindow: false CenterWindow: false DisplayDocTitle: false NonFullScreenPageMode: UseNone Direction: L2R ViewArea: CropBox ViewClip: CropBox PrintArea: CropBox PageClip: CropBox PageLayout: SinglePage PageMode: UseOutlines Language: en-US Outlines: Item: Title: Divergence time estimation using ddRAD data and an isolation-with-migration model applied to water vole populations of Arvicola Children: Item: Title: Results Children: Item: Title: Sequence assembly of ddRAD reads. Item: Title: Population structure. Item: Title: Estimation of ddRAD loci mutation rates in a phylogenetic framework. Item: Title: Application of an isolation-with-migration model to the ddRAD loci. Item: Title: Discussion Children: Item: Title: Suitability of ddRAD loci for IMa3 analysis. Item: Title: Evolutionary history and taxonomy of Arvicola. Item: Title: Conclusions Item: Title: Methods Children: Item: Title: Samples. Item: Title: Ethics statement. Item: Title: ddRAD library preparation and analysis. Item: Title: Genomic tree and population structure analysis. Item: Title: Estimation of specific mutation rates of ddRAD loci from rodent sequences. Item: Title: Isolation-with-migration analyses. Item: Title: References Item: Title: Acknowledgements Info: Title: Divergence time estimation using ddRAD data and an isolation-with-migration model applied to water vole populations of Arvicola Author: Alfonso Balmori-de la Puente Subject: Scientific Reports, https://doi.org/10.1038/s41598-022-07877-y Creator: Springer Producer: Adobe PDF Library 15.0; modified using iText® 5.3.5 ©2000-2012 1T3XT BVBA (SPRINGER SBM; licensed version) CreationDate: Tue Mar 08 09:53:47 CET 2022 ModDate: Tue Mar 08 10:21:05 CET 2022 ID: 0xfcce84e2a0e00da7bf375dd276206185, 0x7133afd8cf58af63ac83faa5d30246a4 Filters: FilterPipeline: FlateDecode FilterPipeline: DCTDecode Images: Image: NisoImageMetadata: FormatName: image/jpg CompressionScheme: JPEG ImageWidth: 14 ImageHeight: 14 ColorSpace: RGB BitsPerSample: 8 BitsPerSampleUnit: integer Intent: RelativeColorimetric Name: X Image: NisoImageMetadata: FormatName: image/jpg CompressionScheme: JPEG ImageWidth: 5 ImageHeight: 8 ColorSpace: RGB BitsPerSample: 8 BitsPerSampleUnit: integer Intent: RelativeColorimetric Name: X Image: NisoImageMetadata: FormatName: image/png ImageWidth: 3 ImageHeight: 6 ColorSpace: RGB BitsPerSample: 8 BitsPerSampleUnit: integer Filter: FlateDecode Intent: RelativeColorimetric Name: X Image: NisoImageMetadata: FormatName: image/png ImageWidth: 18 ImageHeight: 18 BitsPerSample: 8 BitsPerSampleUnit: integer Filter: FlateDecode Intent: RelativeColorimetric Decode: 0, 255 Name: X Image: NisoImageMetadata: FormatName: image/jpg CompressionScheme: JPEG ImageWidth: 14 ImageHeight: 14 ColorSpace: RGB BitsPerSample: 8 BitsPerSampleUnit: integer Intent: RelativeColorimetric Name: X Image: NisoImageMetadata: FormatName: image/jpg CompressionScheme: JPEG ImageWidth: 6 ImageHeight: 14 ColorSpace: RGB BitsPerSample: 8 BitsPerSampleUnit: integer Intent: RelativeColorimetric Name: X Image: NisoImageMetadata: FormatName: image/jpg CompressionScheme: JPEG ImageWidth: 4 ImageHeight: 11 ColorSpace: RGB BitsPerSample: 8 BitsPerSampleUnit: integer Intent: RelativeColorimetric Name: X Image: NisoImageMetadata: FormatName: image/jpg CompressionScheme: JPEG ImageWidth: 4 ImageHeight: 9 ColorSpace: RGB BitsPerSample: 8 BitsPerSampleUnit: integer Intent: RelativeColorimetric Name: X Image: NisoImageMetadata: FormatName: image/png ImageWidth: 3 ImageHeight: 5 ColorSpace: RGB BitsPerSample: 8 BitsPerSampleUnit: integer Filter: FlateDecode Intent: RelativeColorimetric Name: X Image: NisoImageMetadata: FormatName: image/png ImageWidth: 18 ImageHeight: 18 BitsPerSample: 8 BitsPerSampleUnit: integer Filter: FlateDecode Intent: RelativeColorimetric Decode: 0, 255 Name: X Image: NisoImageMetadata: FormatName: image/jpg CompressionScheme: JPEG ImageWidth: 14 ImageHeight: 15 ColorSpace: RGB BitsPerSample: 8 BitsPerSampleUnit: integer Intent: RelativeColorimetric Name: X Image: NisoImageMetadata: FormatName: image/png ImageWidth: 22 ImageHeight: 22 BitsPerSample: 8 BitsPerSampleUnit: integer Filter: FlateDecode Intent: RelativeColorimetric Decode: 0, 255 Name: X Image: NisoImageMetadata: FormatName: image/jpg CompressionScheme: JPEG ImageWidth: 12 ImageHeight: 12 ColorSpace: RGB BitsPerSample: 8 BitsPerSampleUnit: integer Intent: RelativeColorimetric Name: X Image: NisoImageMetadata: FormatName: image/jpg CompressionScheme: JPEG ImageWidth: 10 ImageHeight: 9 ColorSpace: RGB BitsPerSample: 8 BitsPerSampleUnit: integer Intent: RelativeColorimetric Name: X Image: NisoImageMetadata: FormatName: image/jpg CompressionScheme: JPEG ImageWidth: 14 ImageHeight: 15 ColorSpace: RGB BitsPerSample: 8 BitsPerSampleUnit: integer Intent: RelativeColorimetric Name: X Image: NisoImageMetadata: FormatName: image/png ImageWidth: 1084 ImageHeight: 266 ColorSpace: RGB BitsPerSample: 8 BitsPerSampleUnit: integer Filter: FlateDecode Intent: RelativeColorimetric Name: X Image: NisoImageMetadata: FormatName: image/jpg CompressionScheme: JPEG ImageWidth: 12 ImageHeight: 12 ColorSpace: RGB BitsPerSample: 8 BitsPerSampleUnit: integer Intent: RelativeColorimetric Name: X Image: NisoImageMetadata: FormatName: image/jpg CompressionScheme: JPEG ImageWidth: 10 ImageHeight: 10 ColorSpace: RGB BitsPerSample: 8 BitsPerSampleUnit: integer Intent: RelativeColorimetric Name: X Image: NisoImageMetadata: FormatName: image/jpg CompressionScheme: JPEG ImageWidth: 11 ImageHeight: 11 ColorSpace: RGB BitsPerSample: 8 BitsPerSampleUnit: integer Intent: RelativeColorimetric Name: X Image: NisoImageMetadata: FormatName: image/jpg CompressionScheme: JPEG ImageWidth: 9 ImageHeight: 9 ColorSpace: RGB BitsPerSample: 8 BitsPerSampleUnit: integer Intent: RelativeColorimetric Name: X Image: NisoImageMetadata: FormatName: image/jpg CompressionScheme: JPEG ImageWidth: 18 ImageHeight: 13 ColorSpace: RGB BitsPerSample: 8 BitsPerSampleUnit: integer Intent: RelativeColorimetric Name: X Image: NisoImageMetadata: FormatName: image/png ImageWidth: 1773 ImageHeight: 829 ColorSpace: RGB BitsPerSample: 8 BitsPerSampleUnit: integer Filter: FlateDecode Intent: RelativeColorimetric Name: X Image: NisoImageMetadata: FormatName: image/png ImageWidth: 18 ImageHeight: 18 BitsPerSample: 8 BitsPerSampleUnit: integer Filter: FlateDecode Intent: RelativeColorimetric Decode: 0, 255 Name: X Image: NisoImageMetadata: FormatName: image/jpg CompressionScheme: JPEG ImageWidth: 14 ImageHeight: 10 ColorSpace: RGB BitsPerSample: 8 BitsPerSampleUnit: integer Intent: RelativeColorimetric Name: X Image: NisoImageMetadata: FormatName: image/png ImageWidth: 18 ImageHeight: 18 BitsPerSample: 8 BitsPerSampleUnit: integer Filter: FlateDecode Intent: RelativeColorimetric Decode: 0, 255 Name: X Image: NisoImageMetadata: FormatName: image/jpg CompressionScheme: JPEG ImageWidth: 14 ImageHeight: 14 ColorSpace: RGB BitsPerSample: 8 BitsPerSampleUnit: integer Intent: RelativeColorimetric Name: X Image: NisoImageMetadata: FormatName: image/png ImageWidth: 18 ImageHeight: 18 BitsPerSample: 8 BitsPerSampleUnit: integer Filter: FlateDecode Intent: RelativeColorimetric Decode: 0, 255 Name: X Image: NisoImageMetadata: FormatName: image/jpg CompressionScheme: JPEG ImageWidth: 14 ImageHeight: 15 ColorSpace: RGB BitsPerSample: 8 BitsPerSampleUnit: integer Intent: RelativeColorimetric Name: X Image: NisoImageMetadata: FormatName: image/png ImageWidth: 17 ImageHeight: 18 BitsPerSample: 8 BitsPerSampleUnit: integer Filter: FlateDecode Intent: RelativeColorimetric Decode: 0, 255 Name: X Image: NisoImageMetadata: FormatName: image/jpg CompressionScheme: JPEG ImageWidth: 14 ImageHeight: 14 ColorSpace: RGB BitsPerSample: 8 BitsPerSampleUnit: integer Intent: RelativeColorimetric Name: X Image: NisoImageMetadata: FormatName: image/png ImageWidth: 1100 ImageHeight: 90 ColorSpace: black is zero BitsPerSample: 1 BitsPerSampleUnit: integer Filter: FlateDecode Intent: RelativeColorimetric Name: X Fonts: Type0: Font: BaseFont: TANZLH+Code2000 Encoding: Identity-H ToUnicode: true Font: BaseFont: AEQBKT+Corbel-Bold Encoding: Identity-H ToUnicode: true Font: BaseFont: QEYDAN+Corbel Encoding: Identity-H ToUnicode: true Type1: Font: BaseFont: WXWDNF+Wingdings-Regular FontSubset: true FirstChar: 0 LastChar: 255 FontDescriptor: FontName: WXWDNF+Wingdings-Regular Flags: Nonsymbolic FontBBox: 0, -103, 1359, 439 FontFile3: true Encoding: WinAnsiEncoding ToUnicode: true Font: BaseFont: XARVPZ+ArialMT FontSubset: true FirstChar: 32 LastChar: 121 FontDescriptor: FontName: XARVPZ+ArialMT Flags: Nonsymbolic FontBBox: -222, -325, 1072, 1037 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: ArialMT3 FirstChar: 32 LastChar: 121 FontDescriptor: FontName: ArialMT3 Flags: Nonsymbolic FontBBox: -222, -325, 1072, 1037 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: TANZLH+Arial-BoldMT FontSubset: true FirstChar: 32 LastChar: 66 FontDescriptor: FontName: TANZLH+Arial-BoldMT Flags: Nonsymbolic FontBBox: -167, -376, 1075, 1048 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: MinionPro-Bold FirstChar: 0 LastChar: 255 FontDescriptor: FontName: MinionPro-Bold Flags: Serif, Nonsymbolic FontBBox: -319, -360, 1684, 1024 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true ToUnicode: true Font: BaseFont: XARVPZ+Arial-ItalicMT FontSubset: true FirstChar: 32 LastChar: 117 FontDescriptor: FontName: XARVPZ+Arial-ItalicMT Flags: Nonsymbolic FontBBox: -262, -325, 1082, 1025 FontFile3: true Encoding: WinAnsiEncoding Font: BaseFont: ArialMT2 FirstChar: 31 LastChar: 121 FontDescriptor: FontName: ArialMT2 Flags: Nonsymbolic FontBBox: -222, -325, 1072, 1037 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true Font: BaseFont: MinionPro-Regular FirstChar: 0 LastChar: 255 FontDescriptor: FontName: MinionPro-Regular Flags: Serif, Nonsymbolic FontBBox: -290, -360, 1684, 989 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true ToUnicode: true Font: BaseFont: MinionPro-It FirstChar: 0 LastChar: 255 FontDescriptor: FontName: MinionPro-It Flags: Serif, Nonsymbolic, Italic FontBBox: -201, -360, 1684, 1002 FontFile3: true EncodingDictionary: BaseEncoding: WinAnsiEncoding Differences: true ToUnicode: true TrueType: Font: BaseFont: QOACVN+TimesNewRomanPSMT FontSubset: true FirstChar: 32 LastChar: 121 FontDescriptor: FontName: QOACVN+TimesNewRomanPSMT Flags: Serif, Nonsymbolic FontBBox: -568, -307, 2046, 1040 FontFile2: true Encoding: WinAnsiEncoding ToUnicode: true Font: BaseFont: Corbel-BoldItalic FirstChar: 0 LastChar: 255 FontDescriptor: FontName: Corbel-BoldItalic Flags: Nonsymbolic, Italic FontBBox: -494, -239, 1194, 952 FontFile2: true Encoding: WinAnsiEncoding ToUnicode: true Font: BaseFont: Corbel2 FirstChar: 0 LastChar: 255 FontDescriptor: FontName: Corbel2 Flags: Nonsymbolic FontBBox: -553, -239, 1110, 952 FontFile2: true Encoding: WinAnsiEncoding ToUnicode: true CIDFontType2: Font: BaseFont: TANZLH+Code2000 CIDSystemInfo: Registry: Adobe Registry: Identity Supplement: 0 FontDescriptor: FontName: TANZLH+Code2000 Flags: Serif, Symbolic FontBBox: -1111, -295, 2107, 977 FontFile2: true Font: BaseFont: JEHJLB+Corbel CIDSystemInfo: Registry: Adobe Registry: Identity Supplement: 0 FontDescriptor: FontName: JEHJLB+Corbel Flags: Symbolic FontBBox: -553, -239, 1110, 952 FontFile2: true Font: BaseFont: AEQBKT+Corbel-Bold CIDSystemInfo: Registry: Adobe Registry: Identity Supplement: 0 FontDescriptor: FontName: AEQBKT+Corbel-Bold Flags: Symbolic FontBBox: -556, -239, 1155, 952 FontFile2: true XMP: 2022-03-08T13:53:47+05:30 Springer 2022-03-08T10:21:05+01:00 2022-03-08T10:21:05+01:00 application/pdf https://doi.org/10.1038/s41598-022-07877-y Nature Publishing Group UK Scientific Reports, https://doi.org/10.1038/s41598-022-07877-y Divergence time estimation using ddRAD data and an isolation-with-migration model applied to water vole populations of Arvicola Alfonso Balmori-de la Puente Jacint Ventura Marcos Miñarro Aitor Somoano Jody Hey Jose Castresana 10.1038/s41598-022-07877-y 2010-04-23 true springer.com springerlink.com https://doi.org/10.1038/s41598-022-07877-y 10.1038/s41598-022-07877-y 2045-2322 journal Scientific Reports The Author(s) 2010-04-23 true 10.1038/s41598-022-07877-y noindex springer.com springerlink.com VoR uuid:99ec6531-073b-490d-a5ec-306975b83214 uuid:b608490e-4ba5-44d8-99bc-58c832467adb default 1 converted uuid:63423cc6-6abf-4453-830a-c6b37664cf12 converted to PDF/A-2b pdfToolbox 2022-03-08T13:54:39+05:30 converted uuid:956e50ad-f315-4b33-b8ea-4c54b9782214 converted to PDF/A-2b pdfToolbox 2022-03-08T13:55:17+05:30 Adobe PDF Library 15.0; modified using iText® 5.3.5 ©2000-2012 1T3XT BVBA (SPRINGER SBM; licensed version) 2 B http://ns.adobe.com/pdfx/1.3/ pdfx Adobe Document Info PDF eXtension Schema external Mirrors crossmark:MajorVersionDate CrossmarkMajorVersionDate Text external Mirrors crossmark:CrossmarkDomainExclusive CrossmarkDomainExclusive Text internal Mirrors crossmark:DOI doi Text external Mirrors crossmark:CrosMarkDomains CrossMarkDomains seq Text internal A name object indicating whether the document has been modified to include trapping information robots Text internal ID of PDF/X standard GTS_PDFXVersion Text internal Conformance level of PDF/X standard GTS_PDFXConformance Text internal Company creating the PDF Company Text internal Date when document was last modified SourceModified Text http://crossref.org/crossmark/1.0/ crossmark Crossmark Schema internal Usual same as prism:doi DOI Text external The date when a publication was publishe. MajorVersionDate Text internal CrossmarkDomainExclusive CrossmarkDomainExclusive Text internal CrossMarkDomains CrossMarkDomains seq Text http://prismstandard.org/namespaces/basic/2.0/ prism Prism Schema external This element provides the url for an article or unit of content. The attribute platform is optionally allowed for situations in which multiple URLs must be specified. PRISM recommends that a subset of the PCV platform values, namely “mobile” and “web”, be used in conjunction with this element. NOTE: PRISM recommends against the use of the #other value allowed in the PRISM Platform controlled vocabulary. In lieu of using #other please reach out to the PRISM group at prism-wg@yahoogroups.com to request addition of your term to the Platform Controlled Vocabulary. url URI external The Digital Object Identifier for the article. The DOI may also be used as the dc:identifier. If used as a dc:identifier, the URI form should be captured, and the bare identifier should also be captured using prism:doi. If an alternate unique identifier is used as the required dc:identifier, then the DOI should be specified as a bare identifier within prism:doi only. If the URL associated with a DOI is to be specified, then prism:url may be used in conjunction with prism:doi in order to provide the service endpoint (i.e. the URL). doi Text external ISSN for an electronic version of the issue in which the resource occurs. Permits publishers to include a second ISSN, identifying an electronic version of the issue in which the resource occurs (therefore e(lectronic)Issn. If used, prism:eIssn MUST contain the ISSN of the electronic version. issn Text internal Volume number volume Text internal Issue number number Text internal Starting page startingPage Text internal Ending page endingPage Text external The aggregation type specifies the unit of aggregation for a content collection. Comment PRISM recommends that the PRISM Aggregation Type Controlled Vocabulary be used to provide values for this element. Note: PRISM recommends against the use of the #other value currently allowed in this controlled vocabulary. In lieu of using #other please reach out to the PRISM group at info@prismstandard.org to request addition of your term to the Aggregation Type Controlled Vocabulary. aggregationType Text external Title of the magazine, or other publication, in which a resource was/will be published. Typically this will be used to provide the name of the magazine an article appeared in as metadata for the article, along with information such as the article title, the publisher, volume, number, and cover date. Note: Publication name can be used to differentiate between a print magazine and the online version if the names are different such as “magazine” and “magazine.com.” publicationName Text external Copyright copyright Text http://ns.adobe.com/pdf/1.3/ pdf Adobe PDF Schema internal A name object indicating whether the document has been modified to include trapping information Trapped Text http://ns.adobe.com/xap/1.0/mm/ xmpMM XMP Media Management Schema internal UUID based identifier for specific incarnation of a document InstanceID URI internal The common identifier for all versions and renditions of a document. DocumentID URI internal The common identifier for all versions and renditions of a document. OriginalDocumentID URI internal A reference to the original document from which this one is derived. It is a minimal reference; missing components can be assumed to be unchanged. For example, a new version might only need to specify the instance ID and version number of the previous version, or a rendition might only need to specify the instance ID and rendition class of the original. DerivedFrom ResourceRef Identifies a portion of a document. This can be a position at which the document has been changed since the most recent event history (stEvt:changed). For a resource within an xmpMM:Ingredients list, the ResourceRef uses this type to identify both the portion of the containing document that refers to the resource, and the portion of the referenced resource that is referenced. http://ns.adobe.com/xap/1.0/sType/Part# stPart Part http://www.aiim.org/pdfa/ns/id/ pdfaid PDF/A ID Schema internal Part of PDF/A standard part Integer internal Amendment of PDF/A standard amd Text internal Conformance level of PDF/A standard conformance Text http://ns.adobe.com/xap/1.0/t/pg/ xmpTPg XMP Paged-Text internal XMP08 Spec: An ordered array of plate names that are needed to print the document (including any in contained documents). PlateNames Seq Text internal A structure containing the characteristics of a font used in a document Fonts Bag Font A structure containing the characteristics of a font used in a document. http://ns.adobe.com/xap/1.0/sType/Font# stFnt Font http://www.niso.org/schemas/jav/1.0/ jav NISO external Values for Journal Article Version are one of the following: AO = Author’s Original SMUR = Submitted Manuscript Under Review AM = Accepted Manuscript P = Proof VoR = Version of Record CVoR = Corrected Version of Record EVoR = Enhanced Version of Record journal_article_version Closed Choice of Text Pages: Page: Sequence: 1 Annotations: Annotation: Subtype: Link Rect: 199, 273, 202, 261 Flags: Print AppearanceDictionary: true Destination: 321 Annotation: Subtype: Link Rect: 201, 263, 204, 251 Flags: Print AppearanceDictionary: true Destination: 321 Annotation: Subtype: Link Rect: 489, 243, 492, 231 Flags: Print AppearanceDictionary: true Destination: 321 Annotation: Subtype: Link Rect: 493, 243, 496, 231 Flags: Print AppearanceDictionary: true Destination: 321 Annotation: Subtype: Link Rect: 447, 213, 450, 201 Flags: Print AppearanceDictionary: true Destination: 321 Annotation: Subtype: Link Rect: 453, 213, 456, 201 Flags: Print AppearanceDictionary: true Destination: 321 Annotation: Subtype: Link Rect: 429, 203, 431, 191 Flags: Print AppearanceDictionary: true Destination: 321 Annotation: Subtype: Link Rect: 433, 203, 436, 191 Flags: Print AppearanceDictionary: true Destination: 367 Annotation: Subtype: Link Rect: 250, 183, 256, 171 Flags: Print AppearanceDictionary: true Destination: 367 Annotation: Subtype: Link Rect: 258, 183, 263, 171 Flags: Print AppearanceDictionary: true Destination: 367 Annotation: Subtype: Link Rect: 191, 173, 197, 161 Flags: Print AppearanceDictionary: true Destination: 367 Annotation: Subtype: Link Rect: 539, 173, 545, 161 Flags: Print AppearanceDictionary: true Destination: 367 Annotation: Subtype: Link Rect: 546, 173, 552, 161 Flags: Print AppearanceDictionary: true Destination: 367 Annotation: Subtype: Link Rect: 481, 675, 556, 658 Flags: Print AppearanceDictionary: true Thumb: true Page: Sequence: 2 Annotations: Annotation: Subtype: Link Rect: 243, 684, 249, 672 Flags: Print AppearanceDictionary: true Destination: 367 Annotation: Subtype: Link Rect: 250, 684, 256, 672 Flags: Print AppearanceDictionary: true Destination: 367 Annotation: Subtype: Link Rect: 340, 684, 346, 672 Flags: Print AppearanceDictionary: true Destination: 367 Annotation: Subtype: Link Rect: 349, 684, 354, 672 Flags: Print AppearanceDictionary: true Destination: 367 Annotation: Subtype: Link Rect: 483, 654, 489, 642 Flags: Print AppearanceDictionary: true Destination: 367 Annotation: Subtype: Link Rect: 490, 654, 496, 642 Flags: Print AppearanceDictionary: true Destination: 367 Annotation: Subtype: Link Rect: 268, 634, 274, 622 Flags: Print AppearanceDictionary: true Destination: 367 Annotation: Subtype: Link Rect: 277, 634, 283, 622 Flags: Print AppearanceDictionary: true Destination: 367 Annotation: Subtype: Link Rect: 315, 594, 321, 582 Flags: Print AppearanceDictionary: true Destination: 367 Annotation: Subtype: Link Rect: 184, 574, 189, 562 Flags: Print AppearanceDictionary: true Destination: 367 Annotation: Subtype: Link Rect: 192, 574, 198, 562 Flags: Print AppearanceDictionary: true Destination: 367 Annotation: Subtype: Link Rect: 359, 564, 365, 552 Flags: Print AppearanceDictionary: true Destination: 367 Annotation: Subtype: Link Rect: 366, 564, 371, 552 Flags: Print AppearanceDictionary: true Destination: 367 Annotation: Subtype: Link Rect: 174, 544, 179, 532 Flags: Print AppearanceDictionary: true Destination: 367 Annotation: Subtype: Link Rect: 181, 544, 187, 532 Flags: Print AppearanceDictionary: true Destination: 367 Annotation: Subtype: Link Rect: 354, 534, 360, 522 Flags: Print AppearanceDictionary: true Destination: 367 Annotation: Subtype: Link Rect: 286, 514, 292, 502 Flags: Print AppearanceDictionary: true Destination: 367 Annotation: Subtype: Link Rect: 294, 514, 299, 502 Flags: Print AppearanceDictionary: true Destination: 367 Annotation: Subtype: Link Rect: 373, 474, 378, 462 Flags: Print AppearanceDictionary: true Destination: 367 Annotation: Subtype: Link Rect: 332, 414, 338, 402 Flags: Print AppearanceDictionary: true Destination: 367 Annotation: Subtype: Link Rect: 218, 404, 224, 392 Flags: Print AppearanceDictionary: true Destination: 367 Annotation: Subtype: Link Rect: 225, 404, 231, 392 Flags: Print AppearanceDictionary: true Destination: 367 Annotation: Subtype: Link Rect: 232, 404, 237, 392 Flags: Print AppearanceDictionary: true Destination: 367 Annotation: Subtype: Link Rect: 382, 394, 387, 382 Flags: Print AppearanceDictionary: true Destination: 367 Annotation: Subtype: Link Rect: 328, 364, 334, 352 Flags: Print AppearanceDictionary: true Destination: 367 Annotation: Subtype: Link Rect: 335, 364, 341, 352 Flags: Print AppearanceDictionary: true Destination: 367 Annotation: Subtype: Link Rect: 311, 344, 317, 332 Flags: Print AppearanceDictionary: true Destination: 367 Annotation: Subtype: Link Rect: 218, 162, 223, 150 Flags: Print AppearanceDictionary: true Destination: 86 Annotation: Subtype: Link Rect: 266, 152, 272, 140 Flags: Print AppearanceDictionary: true Destination: 367 Annotation: Subtype: Link Rect: 178, 122, 184, 110 Flags: Print AppearanceDictionary: true Destination: 367 Annotation: Subtype: Link Rect: 401, 60, 406, 48 Flags: Print AppearanceDictionary: true Destination: 86 Annotation: Subtype: Link Rect: 515, 60, 520, 48 Flags: Print AppearanceDictionary: true Destination: 367 Thumb: true Page: Sequence: 3 Annotations: Annotation: Subtype: Link Rect: 499, 148, 504, 136 Flags: Print AppearanceDictionary: true Destination: 86 Annotation: Subtype: Link Rect: 378, 493, 384, 481 Flags: Print AppearanceDictionary: true Destination: 371 Annotation: Subtype: Link Rect: 351, 483, 357, 471 Flags: Print AppearanceDictionary: true Destination: 371 Annotation: Subtype: Link Rect: 358, 483, 364, 471 Flags: Print AppearanceDictionary: true Destination: 371 Annotation: Subtype: Link Rect: 158, 473, 277, 461 Flags: Print AppearanceDictionary: true Thumb: true Page: Sequence: 4 Annotations: Annotation: Subtype: Link Rect: 521, 683, 526, 671 Flags: Print AppearanceDictionary: true Destination: 367 Annotation: Subtype: Link Rect: 546, 653, 552, 641 Flags: Print AppearanceDictionary: true Destination: 367 Annotation: Subtype: Link Rect: 454, 583, 460, 571 Flags: Print AppearanceDictionary: true Destination: 367 Annotation: Subtype: Link Rect: 447, 573, 453, 561 Flags: Print AppearanceDictionary: true Destination: 367 Annotation: Subtype: Link Rect: 454, 573, 460, 561 Flags: Print AppearanceDictionary: true Destination: 367 Annotation: Subtype: Link Rect: 497, 553, 529, 541 Flags: Print AppearanceDictionary: true Destination: 221 Annotation: Subtype: Link Rect: 235, 501, 241, 489 Flags: Print AppearanceDictionary: true Destination: 367 Annotation: Subtype: Link Rect: 452, 411, 456, 399 Flags: Print AppearanceDictionary: true Destination: 187 Annotation: Subtype: Link Rect: 174, 361, 179, 349 Flags: Print AppearanceDictionary: true Destination: 187 Annotation: Subtype: Link Rect: 478, 311, 482, 299 Flags: Print AppearanceDictionary: true Destination: 187 Annotation: Subtype: Link Rect: 539, 209, 545, 197 Flags: Print AppearanceDictionary: true Destination: 367 Annotation: Subtype: Link Rect: 546, 209, 552, 197 Flags: Print AppearanceDictionary: true Destination: 367 Annotation: Subtype: Link Rect: 471, 169, 475, 157 Flags: Print AppearanceDictionary: true Destination: 187 Annotation: Subtype: Link Rect: 343, 89, 349, 77 Flags: Print AppearanceDictionary: true Destination: 367 Annotation: Subtype: Link Rect: 450, 79, 455, 67 Flags: Print AppearanceDictionary: true Destination: 367 Annotation: Subtype: Link Rect: 210, 69, 215, 57 Flags: Print AppearanceDictionary: true Destination: 367 Thumb: true Page: Sequence: 5 Annotations: Annotation: Subtype: Link Rect: 504, 249, 536, 237 Flags: Print AppearanceDictionary: true Destination: 221 Annotation: Subtype: Link Rect: 411, 209, 416, 197 Flags: Print AppearanceDictionary: true Destination: 367 Annotation: Subtype: Link Rect: 417, 209, 423, 197 Flags: Print AppearanceDictionary: true Destination: 367 Annotation: Subtype: Link Rect: 409, 199, 414, 187 Flags: Print AppearanceDictionary: true Destination: 367 Annotation: Subtype: Link Rect: 416, 199, 421, 187 Flags: Print AppearanceDictionary: true Destination: 371 Annotation: Subtype: Link Rect: 511, 169, 516, 157 Flags: Print AppearanceDictionary: true Destination: 371 Annotation: Subtype: Link Rect: 338, 149, 344, 137 Flags: Print AppearanceDictionary: true Destination: 367 Annotation: Subtype: Link Rect: 464, 149, 469, 137 Flags: Print AppearanceDictionary: true Destination: 367 Annotation: Subtype: Link Rect: 471, 149, 476, 137 Flags: Print AppearanceDictionary: true Destination: 371 Annotation: Subtype: Link Rect: 318, 99, 324, 87 Flags: Print AppearanceDictionary: true Destination: 371 Annotation: Subtype: Link Rect: 325, 99, 331, 87 Flags: Print AppearanceDictionary: true Destination: 371 Thumb: true Page: Sequence: 6 Annotations: Annotation: Subtype: Link Rect: 320, 693, 324, 681 Flags: Print AppearanceDictionary: true Destination: 187 Annotation: Subtype: Link Rect: 415, 673, 420, 661 Flags: Print AppearanceDictionary: true Destination: 367 Annotation: Subtype: Link Rect: 388, 663, 393, 651 Flags: Print AppearanceDictionary: true Destination: 187 Annotation: Subtype: Link Rect: 250, 633, 255, 621 Flags: Print AppearanceDictionary: true Destination: 187 Annotation: Subtype: Link Rect: 441, 623, 446, 611 Flags: Print AppearanceDictionary: true Destination: 371 Annotation: Subtype: Link Rect: 448, 623, 453, 611 Flags: Print AppearanceDictionary: true Destination: 371 Annotation: Subtype: Link Rect: 180, 603, 185, 591 Flags: Print AppearanceDictionary: true Destination: 371 Annotation: Subtype: Link Rect: 428, 573, 434, 561 Flags: Print AppearanceDictionary: true Destination: 371 Annotation: Subtype: Link Rect: 197, 563, 201, 551 Flags: Print AppearanceDictionary: true Destination: 86 Annotation: Subtype: Link Rect: 539, 563, 545, 551 Flags: Print AppearanceDictionary: true Destination: 367 Annotation: Subtype: Link Rect: 546, 563, 552, 551 Flags: Print AppearanceDictionary: true Destination: 367 Annotation: Subtype: Link Rect: 351, 543, 356, 531 Flags: Print AppearanceDictionary: true Destination: 367 Annotation: Subtype: Link Rect: 499, 513, 505, 501 Flags: Print AppearanceDictionary: true Destination: 367 Annotation: Subtype: Link Rect: 272, 463, 278, 451 Flags: Print AppearanceDictionary: true Destination: 367 Annotation: Subtype: Link Rect: 353, 453, 357, 441 Flags: Print AppearanceDictionary: true Destination: 187 Annotation: Subtype: Link Rect: 539, 443, 545, 431 Flags: Print AppearanceDictionary: true Destination: 367 Annotation: Subtype: Link Rect: 546, 443, 552, 431 Flags: Print AppearanceDictionary: true Destination: 367 Annotation: Subtype: Link Rect: 262, 403, 268, 391 Flags: Print AppearanceDictionary: true Destination: 367 Annotation: Subtype: Link Rect: 269, 403, 275, 391 Flags: Print AppearanceDictionary: true Destination: 367 Annotation: Subtype: Link Rect: 276, 403, 281, 391 Flags: Print AppearanceDictionary: true Destination: 367 Annotation: Subtype: Link Rect: 280, 393, 285, 381 Flags: Print AppearanceDictionary: true Destination: 86 Annotation: Subtype: Link Rect: 437, 393, 442, 381 Flags: Print AppearanceDictionary: true Destination: 86 Annotation: Subtype: Link Rect: 287, 373, 291, 361 Flags: Print AppearanceDictionary: true Destination: 187 Annotation: Subtype: Link Rect: 546, 343, 552, 331 Flags: Print AppearanceDictionary: true Destination: 367 Annotation: Subtype: Link Rect: 331, 139, 337, 127 Flags: Print AppearanceDictionary: true Destination: 367 Annotation: Subtype: Link Rect: 338, 139, 344, 127 Flags: Print AppearanceDictionary: true Destination: 367 Annotation: Subtype: Link Rect: 317, 65, 323, 53 Flags: Print AppearanceDictionary: true Destination: 371 Annotation: Subtype: Link Rect: 530, 65, 536, 53 Flags: Print AppearanceDictionary: true Destination: 367 Annotation: Subtype: Link Rect: 329, 55, 334, 43 Flags: Print AppearanceDictionary: true Destination: 367 Thumb: true Page: Sequence: 7 Annotations: Annotation: Subtype: Link Rect: 273, 734, 278, 722 Flags: Print AppearanceDictionary: true Destination: 367 Annotation: Subtype: Link Rect: 493, 614, 498, 602 Flags: Print AppearanceDictionary: true Destination: 367 Annotation: Subtype: Link Rect: 473, 584, 479, 572 Flags: Print AppearanceDictionary: true Destination: 367 Annotation: Subtype: Link Rect: 202, 564, 208, 552 Flags: Print AppearanceDictionary: true Destination: 371 Annotation: Subtype: Link Rect: 303, 424, 309, 412 Flags: Print AppearanceDictionary: true Destination: 371 Annotation: Subtype: Link Rect: 280, 382, 283, 370 Flags: Print AppearanceDictionary: true Destination: 321 Annotation: Subtype: Link Rect: 408, 362, 414, 350 Flags: Print AppearanceDictionary: true Destination: 371 Annotation: Subtype: Link Rect: 461, 352, 466, 340 Flags: Print AppearanceDictionary: true Destination: 371 Annotation: Subtype: Link Rect: 248, 322, 254, 310 Flags: Print AppearanceDictionary: true Destination: 371 Annotation: Subtype: Link Rect: 237, 312, 243, 300 Flags: Print AppearanceDictionary: true Destination: 367 Annotation: Subtype: Link Rect: 546, 282, 552, 270 Flags: Print AppearanceDictionary: true Destination: 371 Annotation: Subtype: Link Rect: 548, 262, 554, 250 Flags: Print AppearanceDictionary: true Destination: 371 Annotation: Subtype: Link Rect: 449, 232, 455, 220 Flags: Print AppearanceDictionary: true Destination: 371 Annotation: Subtype: Link Rect: 178, 120, 184, 108 Flags: Print AppearanceDictionary: true Destination: 367 Annotation: Subtype: Link Rect: 467, 70, 472, 58 Flags: Print AppearanceDictionary: true Destination: 367 Thumb: true Page: Sequence: 8 Annotations: Annotation: Subtype: Link Rect: 464, 734, 554, 722 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 155, 724, 280, 712 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 371, 664, 377, 652 Flags: Print AppearanceDictionary: true Destination: 371 Annotation: Subtype: Link Rect: 490, 654, 496, 642 Flags: Print AppearanceDictionary: true Destination: 371 Annotation: Subtype: Link Rect: 546, 624, 552, 612 Flags: Print AppearanceDictionary: true Destination: 371 Annotation: Subtype: Link Rect: 451, 604, 457, 592 Flags: Print AppearanceDictionary: true Destination: 367 Annotation: Subtype: Link Rect: 299, 594, 305, 582 Flags: Print AppearanceDictionary: true Destination: 367 Annotation: Subtype: Link Rect: 530, 574, 536, 562 Flags: Print AppearanceDictionary: true Destination: 371 Annotation: Subtype: Link Rect: 436, 534, 441, 522 Flags: Print AppearanceDictionary: true Destination: 371 Annotation: Subtype: Link Rect: 546, 492, 552, 480 Flags: Print AppearanceDictionary: true Destination: 367 Annotation: Subtype: Link Rect: 488, 402, 491, 390 Flags: Print AppearanceDictionary: true Destination: 321 Annotation: Subtype: Link Rect: 242, 382, 247, 370 Flags: Print AppearanceDictionary: true Destination: 371 Annotation: Subtype: Link Rect: 254, 292, 259, 280 Flags: Print AppearanceDictionary: true Destination: 367 Annotation: Subtype: Link Rect: 274, 272, 277, 260 Flags: Print AppearanceDictionary: true Destination: 321 Annotation: Subtype: Link Rect: 421, 242, 554, 230 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 155, 232, 171, 220 Flags: Print AppearanceDictionary: true Thumb: true Page: Sequence: 9 Thumb: true Page: Sequence: 10 Annotations: Annotation: Subtype: Link Rect: 503, 402, 554, 392 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 169, 393, 179, 383 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 418, 385, 501, 375 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 419, 368, 502, 358 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 499, 140, 554, 128 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 155, 130, 259, 118 Flags: Print AppearanceDictionary: true Annotation: Subtype: Link Rect: 351, 100, 443, 88 Flags: Print AppearanceDictionary: true Thumb: true Page: Sequence: 11 Annotations: Annotation: Subtype: Link Rect: 358, 664, 517, 652 Flags: Print AppearanceDictionary: true Thumb: true Checksum: c4b45802 Type: CRC32 Checksum: 5f6a1e5b1721f22337e3445b8f959121 Type: MD5 Checksum: 82d17852447cdddf1d83de0e11176cfd13f28473 Type: SHA-1