54a5a21a7f4389b264f4260b182dc923  pmc_8907432.pdf
2524ed51334f162151a3e018b13bc47b339a1250  pmc_8907432.pdf
71eabfe3de9e0ed59d7b65c1ec7b8be24334fccc3ed26c2b24873f6378536c04  pmc_8907432.pdf

Creator:         Adobe InDesign 16.4 (Macintosh)
Producer:        Adobe PDF Library 16.0
CreationDate:    Mon Mar  7 15:12:37 2022 CET
ModDate:         Tue Mar  8 07:53:09 2022 CET
Custom Metadata: no
Metadata Stream: yes
Tagged:          yes
UserProperties:  no
Suspects:        no
Form:            none
JavaScript:      no
Pages:           3
Encrypted:       no
Page size:       609.449 x 793.701 pts
Page rot:        0
File size:       780479 bytes
Optimized:       no
PDF version:     1.6


name                                 type              encoding         emb sub uni object ID
------------------------------------ ----------------- ---------------- --- --- --- ---------
ERNCKK+CheltenhamITCbyBT-BookItalic  CID Type 0C       Identity-H       yes yes yes    213  0
NFXJPM+CheltenhamITCbyBT-Book        Type 1C           Custom           yes yes yes    197  0
NFXJPM+Cheltenham-Bold               Type 1C           WinAnsi          yes yes yes    199  0
NFXJPM+CheltenhamITCbyBT-BookItalic  Type 1C           Custom           yes yes yes    202  0
NFXJPM+CheltenhamITCbyBT-BoldItalic  TrueType          WinAnsi          yes yes yes    204  0
NFXJPM+CheltenhamITCbyBT-Bold        TrueType          WinAnsi          yes yes yes    206  0


Jhove (Rel. 1.28.0, 2023-05-18)
 Date: 2024-05-07 04:29:07 CEST
 RepresentationInformation: pmc_8907432.pdf
  ReportingModule: PDF-hul, Rel. 1.12.4 (2023-03-16)
  LastModified: 2022-03-28 07:47:16 CEST
  Size: 780479
  Format: PDF
  Version: 1.6
  Status: Well-Formed and valid
  SignatureMatches:
   PDF-hul
  MIMEtype: application/pdf
  Profile: Tagged PDF
  PDFMetadata: 
   Objects: 0
   FreeObjects: 1
   IncrementalUpdates: 0
   DocumentCatalog: 
    PageLayout: SinglePage
    PageMode: UseNone
   Filters: 
    FilterPipeline: FlateDecode
    FilterPipeline: DCTDecode
   Images: 
    Image: 
     NisoImageMetadata: 
      FormatName: image/png
      ImageWidth: 142
      ImageHeight: 142
      ColorSpace: black is zero
      BitsPerSample: 8
      BitsPerSampleUnit: integer
     Filter: FlateDecode
     Intent: RelativeColorimetric
     Name: X
    Image: 
     NisoImageMetadata: 
      FormatName: image/jpg
      CompressionScheme: JPEG
      ImageWidth: 1052
      ImageHeight: 600
      ColorSpace: CMYK
      BitsPerSample: 8
      BitsPerSampleUnit: integer
     Intent: RelativeColorimetric
     Name: X
    Image: 
     NisoImageMetadata: 
      FormatName: image/png
      ImageWidth: 170
      ImageHeight: 170
      ColorSpace: black is zero
      BitsPerSample: 8
      BitsPerSampleUnit: integer
     Filter: FlateDecode
     Intent: RelativeColorimetric
     Name: X
    Image: 
     NisoImageMetadata: 
      FormatName: image/jpg
      CompressionScheme: JPEG
      ImageWidth: 1052
      ImageHeight: 586
      ColorSpace: CMYK
      BitsPerSample: 8
      BitsPerSampleUnit: integer
     Intent: RelativeColorimetric
     Name: X
    Image: 
     NisoImageMetadata: 
      FormatName: image/jpg
      CompressionScheme: JPEG
      ImageWidth: 1052
      ImageHeight: 555
      ColorSpace: CMYK
      BitsPerSample: 8
      BitsPerSampleUnit: integer
     Intent: RelativeColorimetric
     Name: X
   Fonts: 
    Type0: 
     Font: 
      BaseFont: ERNCKK+CheltenhamITCbyBT-BookItalic
      Encoding: Identity-H
      ToUnicode: true
    Type1: 
     Font: 
      BaseFont: NFXJPM+CheltenhamITCbyBT-Book
      FontSubset: true
      FirstChar: 22
      LastChar: 252
      FontDescriptor: 
       FontName: NFXJPM+CheltenhamITCbyBT-Book
       Flags: Serif, Nonsymbolic
       FontBBox: -167, -236, 1138, 974
       FontFile3: true
      EncodingDictionary: 
       BaseEncoding: WinAnsiEncoding
       Differences: true
      ToUnicode: true
     Font: 
      BaseFont: NFXJPM+Cheltenham-Bold
      FontSubset: true
      FirstChar: 32
      LastChar: 121
      FontDescriptor: 
       FontName: NFXJPM+Cheltenham-Bold
       Flags: Serif, Nonsymbolic
       FontBBox: -176, -232, 1194, 948
       FontFile3: true
      Encoding: WinAnsiEncoding
      ToUnicode: true
     Font: 
      BaseFont: NFXJPM+CheltenhamITCbyBT-BookItalic
      FontSubset: true
      FirstChar: 28
      LastChar: 252
      FontDescriptor: 
       FontName: NFXJPM+CheltenhamITCbyBT-BookItalic
       Flags: Serif, Nonsymbolic, Italic
       FontBBox: -187, -236, 1081, 963
       FontFile3: true
      EncodingDictionary: 
       BaseEncoding: WinAnsiEncoding
       Differences: true
      ToUnicode: true
    TrueType: 
     Font: 
      BaseFont: NFXJPM+CheltenhamITCbyBT-BoldItalic
      FontSubset: true
      FirstChar: 32
      LastChar: 148
      FontDescriptor: 
       FontName: NFXJPM+CheltenhamITCbyBT-BoldItalic
       Flags: Serif, Nonsymbolic
       FontBBox: -189, -236, 1127, 963
       FontFile2: true
      Encoding: WinAnsiEncoding
      ToUnicode: true
     Font: 
      BaseFont: NFXJPM+CheltenhamITCbyBT-Bold
      FontSubset: true
      FirstChar: 32
      LastChar: 177
      FontDescriptor: 
       FontName: NFXJPM+CheltenhamITCbyBT-Bold
       Flags: Serif, Nonsymbolic
       FontBBox: -167, -236, 1190, 963
       FontFile2: true
      Encoding: WinAnsiEncoding
      ToUnicode: true
    CIDFontType0: 
     Font: 
      BaseFont: ERNCKK+CheltenhamITCbyBT-BookItalic
      CIDSystemInfo: 
       Registry: Adobe
       Registry: Identity
       Supplement: 0
      FontDescriptor: 
       FontName: ERNCKK+CheltenhamITCbyBT-BookItalic
       Flags: Serif, Symbolic, Italic
       FontBBox: -187, -236, 1081, 963
       FontFile3: true
   XMP: <x:xmpmeta xmlns:x="adobe:ns:meta/" x:xmptk="Adobe XMP Core 7.0-c000 79.1357c9e, 2021/07/14-00:39:56        ">
   <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#">
      <rdf:Description rdf:about=""
            xmlns:xmp="http://ns.adobe.com/xap/1.0/"
            xmlns:dc="http://purl.org/dc/elements/1.1/"
            xmlns:xmpMM="http://ns.adobe.com/xap/1.0/mm/"
            xmlns:pdf="http://ns.adobe.com/pdf/1.3/">
         <xmp:ModifyDate>2022-03-08T09:53:09+03:00</xmp:ModifyDate>
         <xmp:CreateDate>2022-03-07T17:12:37+03:00</xmp:CreateDate>
         <xmp:MetadataDate>2022-03-08T09:53:09+03:00</xmp:MetadataDate>
         <xmp:CreatorTool>Adobe InDesign 16.4 (Macintosh)</xmp:CreatorTool>
         <dc:format>application/pdf</dc:format>
         <xmpMM:DocumentID>uuid:6d04ab3e-c3c1-4a6a-be96-81e54265010b</xmpMM:DocumentID>
         <xmpMM:InstanceID>uuid:67269d07-9c39-4cff-8e8b-26bdf6c48983</xmpMM:InstanceID>
         <pdf:Producer>Adobe PDF Library 16.0</pdf:Producer>
      </rdf:Description>
   </rdf:RDF>
</x:xmpmeta>
   Pages: 
    Page: 
     Sequence: 1
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 89, 591, 99, 602
      Annotation: 
       Subtype: Link
       Rect: 197, 591, 209, 602
      Annotation: 
       Subtype: Link
       Rect: 294, 591, 306, 603
      Annotation: 
       Subtype: Link
       Rect: 409, 591, 420, 602
      Annotation: 
       Subtype: Link
       Rect: 251, 577, 262, 588
    Page: 
     Sequence: 2
     Annotations: 
      Annotation: 
       Subtype: Link
       Rect: 314, 227, 565, 237
    Page: 
     Sequence: 3
  Checksum: 6ed9ea1e
   Type: CRC32
  Checksum: 54a5a21a7f4389b264f4260b182dc923
   Type: MD5
  Checksum: 2524ed51334f162151a3e018b13bc47b339a1250
   Type: SHA-1
  Checksum: 71eabfe3de9e0ed59d7b65c1ec7b8be24334fccc3ed26c2b24873f6378536c04
   Type: SHA-256