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Title:          Epigenetic landscape in the kick-and-kill therapeutic vaccine BCN02 clinical trial is associated with antiretroviral treatment interruption (ATI) outcome
Subject:        eBioMedicine, 78 (2022) 103956. doi:10.1016/j.ebiom.2022.103956
Keywords:       "HIV-1 vaccine"; "Epigenetics"; "DNA methylation"
Author:         Bruna Oriol-Tordera
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      Title: Epigenetic landscape in the kick-and-kill therapeutic vaccine BCN02 clinical trial is associated with antiretroviral treatment interruption (ATI) outcome
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        Title: Introduction
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        Title: Methods
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          Title: Study design
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          Title: PBMCs and CD4 T cell isolation and acid nucleic extraction
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          Title: RNAseq library preparation and sequencing and data pre-processing
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          Title: DNA methylation array
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          Title: Differential gene expression and DNA methylation analysis
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          Title: Gene expression and DNA methylation profiles
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          Title: Integrated functional pathways analysis of genes and CpG positions modulated during the kick-and-kill therapy
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          Title: Chromatin state and histone marks enrichment
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          Title: Transcription factor (TF) enrichment
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          Title: Evaluation of DNA methylation and gene expression capacity to discriminate between early and late rebound
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          Title: Determination of viral parameters
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          Title: Statistics
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          Title: Ethics
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          Title: Data deposition and material sharing
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          Title: Role of the funding source
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        Title: Results
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          Title: Gene expression and DNA methylation changes one week after MVA.HIVconsv vaccination in the BCN02 study
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          Title: Cumulative transcriptional and methylation changes after vaccination and RMD intervention
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          Title: DNA methylation imprints after intervention can predict viral rebound before ATI
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   Type: CRC32
  Checksum: 63b57ebdb900355ac3daaf45cf7ad1f1
   Type: MD5
  Checksum: 7c9626f19e6f41f2d458953fc847dc1f3811240f
   Type: SHA-1