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Title:          Conducting clinical trials in persons with Down syndrome: summary from the NIH INCLUDE Down syndrome clinical trials readiness working group
Subject:        Journal of Neurodevelopmental Disorders, https://doi.org/10.1186/s11689-022-09435-z
Keywords:       Down syndrome;Intellectual disability;Clinical trials;Clinical research;Research engagement;Recruitment
Author:          Nicole T. Baumer
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     Item: 
      Title: Conducting clinical trials in persons with Down syndrome: summary from the NIH INCLUDE Down syndrome clinical trials readiness working group
      Children: 
       Item: 
        Title: Abstract 
       Item: 
        Title: Backgroundintroduction
        Children: 
         Item: 
          Title: Current state of clinical trials in the Down syndrome population
         Item: 
          Title: Challenges and barriers for conducting clinical trials
          Children: 
           Item: 
            Title: Barriers faced by families
           Item: 
            Title: Ethical and logistical barriers faced by researchers
           Item: 
            Title: Challenges specific to clinical trials targeting cognition
         Item: 
          Title: Clinical trials readiness working group objectives
         Item: 
          Title: Recruitment and retention: strategies to promote engagement and inclusion
          Children: 
           Item: 
            Title: Engagement with individuals with DS, their familiescare partners, and community advocacy organizations
           Item: 
            Title: Collaboration between researchers, clinicians, stakeholder groups, and advocacy organizations
           Item: 
            Title: Engagement of underrepresented groups
           Item: 
            Title: Providing accessible information
           Item: 
            Title: Reducing study burden
           Item: 
            Title: Legal and ethical considerations
         Item: 
          Title: Cohort development across the lifespan
         Item: 
          Title: Building an investigator pipeline in Down syndrome research
       Item: 
        Title: Discussionkey points
       Item: 
        Title: Conclusions
       Item: 
        Title: Acknowledgements
       Item: 
        Title: References
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