bc1f72995d6babeaa2bbd54d7646611f pmc_8989015.pdf 03826b3c5f772fa53c83507d8d4a9bc27c02e90d pmc_8989015.pdf a7ba49d4d2125044b955ccfd5fc6d98325a790e2122bf878fc07a73918006ba8 pmc_8989015.pdf Title: How Does Immunomodulatory Nanoceria Work? ROS and Immunometabolism Subject: Dysregulation of the immune system is associated with an overproduction of metabolic reactive oxygen species (ROS) and consequent oxidative stress Keywords: nanoparticles, nanoceria, inflammation, macrophages, immunemetabolism, metabolism, ROS - reactive oxygen species, entropy Author: Lena M. Ernst Creator: Arbortext Advanced Print Publisher 10.0.1306/W Unicode Producer: Acrobat Distiller 7.0 (Windows) CreationDate: Thu Mar 24 02:43:34 2022 CET ModDate: Thu Mar 24 04:40:50 2022 CET Tagged: no UserProperties: no Suspects: no Form: none JavaScript: no Pages: 12 Encrypted: no Page size: 595.276 x 779.528 pts Page rot: 0 File size: 1540783 bytes Optimized: yes PDF version: 1.6 name type encoding emb sub uni object ID ------------------------------------ ----------------- ---------------- --- --- --- --------- HLMFNK+AdvOT34fe1490.B Type 1C WinAnsi yes yes no 593 0 HLMFNL+AdvOT01861455.I Type 1C WinAnsi yes yes no 594 0 HLMFNM+AdvOT1deab444.I Type 1C WinAnsi yes yes no 595 0 HLMFNN+AdvOT1deab444.I+20 Type 1C WinAnsi yes yes no 596 0 HLMFNO+AdvPSA323 Type 1C WinAnsi yes yes no 597 0 HLMFNP+AdvOT6e5d2ec0 Type 1C WinAnsi yes yes no 598 0 HLMFOA+AdvOT6e5d2ec0+fb Type 1C Custom yes yes yes 599 0 HLMFPB+AdvOT34fe1490.B+fb Type 1C Custom yes yes yes 605 0 HLMFPC+AdvOT1ef757c0 Type 1C WinAnsi yes yes no 606 0 HLMFPD+AdvOT1ef757c0+fb Type 1C Custom yes yes yes 607 0 HLMGAD+AdvOT6601a1b9.BI Type 1C WinAnsi yes yes no 615 0 HLMGFC+AdvOT1ef757c0+20 Type 1C WinAnsi yes yes no 316 0 HLMGGD+AdvOT7d6df7ab.I Type 1C WinAnsi yes yes no 323 0 HLMGGE+AdvOTb65e897d.B Type 1C WinAnsi yes yes no 322 0 HLMHKN+AdvOTbde271ed Type 1C WinAnsi yes yes no 324 0 HLMING+AdvOT1ef757c0+22 Type 1C Custom yes yes no 330 0 HLMINH+AdvP4C4E51 Type 1C WinAnsi yes yes no 329 0 HLMINI+AdvTT3713a231+20 Type 1C Custom yes yes yes 328 0 HLMIPI+AdvOTd877c31c Type 1C WinAnsi yes yes no 333 0 HLMJCI+AdvTT58d178b9+03 Type 1C Custom yes yes yes 334 0 HLMJCJ+AdvOT1ef757c0+01 Type 1C MacRoman yes yes no 338 0 HLMJEJ+AdvOT3f84ef53 Type 1C WinAnsi yes yes no 340 0 HLMJGJ+AdvOT7d6df7ab.I+20 Type 1C WinAnsi yes yes no 343 0 HLMJGK+AdvOTb65e897d.B+fb Type 1C Custom yes yes yes 341 0 HLMJGL+AdvOTb65e897d.B+20 Type 1C WinAnsi yes yes no 342 0 Jhove (Rel. 1.22.1, 2019-04-17) Date: 2022-06-11 02:23:46 CEST RepresentationInformation: pmc_8989015.pdf ReportingModule: PDF-hul, Rel. 1.12.1 (2019-04-17) LastModified: 2022-04-26 17:56:33 CEST Size: 1540783 Format: PDF Version: 1.6 Status: Well-Formed, but not valid SignatureMatches: PDF-hul ID: PDF-HUL-122 ErrorMessage: edu.harvard.hul.ois.jhove.module.pdf.PdfInvalidException: Invalid indirect destination - 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ROS and Immunometabolism Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@ed9d034 Children: Item: Title: Introduction Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@6121c9d6 Item: Title: A Brief Overview on Metabolism, Mitochondria, and ROS Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@87f383f Item: Title: The Nanoceria Immunomodulatory Mechanism Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@4eb7f003 Item: Title: Pharmacological Development of Nanoceria Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@eafc191 Children: Item: Title: Nanosafety Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@612fc6eb Item: Title: Data Availability Statement Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@1060b431 Item: Title: Author Contributions Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@612679d6 Item: Title: Supplementary Material Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@11758f2a Item: Title: References Destination: edu.harvard.hul.ois.jhove.module.pdf.PdfSimpleObject@e720b71 Info: Title: How Does Immunomodulatory Nanoceria Work? ROS and Immunometabolism Author: Lena M. Ernst Subject: Dysregulation of the immune system is associated with an overproduction of metabolic reactive oxygen species (ROS) and consequent oxidative stress Keywords: nanoparticles, nanoceria, inflammation, macrophages, immunemetabolism, metabolism, ROS - reactive oxygen species, entropy Creator: Arbortext Advanced Print Publisher 10.0.1306/W Unicode Producer: Acrobat Distiller 7.0 (Windows) CreationDate: Thu Mar 24 02:43:34 CET 2022 ModDate: Thu Mar 24 04:40:50 CET 2022 ID: 0xeea8e4f561f1117e82ce4eb995c3e0d2, 0xdbfcd266805caf44bf8cdd017a753bed Filters: FilterPipeline: FlateDecode FilterPipeline: DCTDecode Images: Image: NisoImageMetadata: FormatName: image/png ImageWidth: 2008 ImageHeight: 990 ColorSpace: RGB BitsPerSample: 8 BitsPerSampleUnit: integer Filter: FlateDecode Image: NisoImageMetadata: FormatName: image/jpg CompressionScheme: JPEG ImageWidth: 2008 ImageHeight: 1316 ColorSpace: RGB BitsPerSample: 8 BitsPerSampleUnit: integer Fonts: Type1: Font: BaseFont: 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entropy 2022-03-24T11:40:50+08:00 2022-03-24T09:43:34+08:00 Arbortext Advanced Print Publisher 10.0.1306/W Unicode 2022-03-24T11:40:50+08:00 application/pdf How Does Immunomodulatory Nanoceria Work? ROS and Immunometabolism Lena M. Ernst Victor Puntes Dysregulation of the immune system is associated with an overproduction of metabolic reactive oxygen species (ROS) and consequent oxidative stress nanoparticles nanoceria inflammation macrophages immunemetabolism metabolism ROS - reactive oxygen species entropy uuid:f12c3041-70cc-4a1f-bd35-2ed9cb211225 uuid:70d18daf-937b-4f1f-9b49-f824a069d844 Pages: Page: Label: 1 Annotations: Annotation: Subtype: Link Rect: 175, 606, 478, 627 Annotation: Subtype: Link Rect: 175, 583, 442, 604 Annotation: Subtype: Link Rect: 175, 560, 372, 581 Annotation: Subtype: Link Rect: 516, 404, 549, 414 Annotation: Subtype: Link Rect: 175, 390, 205, 400 Annotation: Subtype: Link Rect: 446, 390, 510, 400 Annotation: Subtype: Link Rect: 357, 121, 361, 131 Destination: 174 Annotation: Subtype: Link Rect: 327, 64, 332, 73 Destination: 174 Annotation: Subtype: Link Rect: 45, 29, 116, 36 Annotation: Subtype: Link Rect: 125, 29, 183, 36 Annotation: Subtype: Link Rect: 420, 29, 549, 36 Annotation: 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