11cc50252fc5efad55de8a8767329c76 pmc_8991834.pdf 9aad07a25e65078e5b1331789589029b5af8811d pmc_8991834.pdf 880b34e9d6da59db1c9cf014f59613b6b66b50217b6729c935dc9f99a57279ca pmc_8991834.pdf Title: Multimarker synaptic protein cerebrospinal fluid panels reflect TDP-43 pathology and cognitive performance in a pathological cohort of frontotemporal lobar degeneration Subject: Molecular Neurodegeneration, https://doi.org/10.1186/s13024-022-00534-y Keywords: Calsyntenin-1;Frontotemporal lobar degeneration;Frontotemporal dementia;Cerebrospinal fluid;Biomarker;TDP-43;Tau Author: Alba Cervantes-González Creator: Adobe InDesign 15.0 (Windows) Producer: Adobe PDF Library 15.0; modified using iText® 5.3.5 ©2000-2012 1T3XT BVBA (SPRINGER SBM; licensed version) CreationDate: Mon Apr 4 15:22:39 2022 CEST ModDate: Fri Apr 8 12:56:56 2022 CEST Tagged: no UserProperties: no Suspects: no Form: none JavaScript: no Pages: 12 Encrypted: no Page size: 595.276 x 790.866 pts Page rot: 0 File size: 3821643 bytes 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(Rel. 1.22.1, 2019-04-17) Date: 2022-05-05 02:30:43 CEST RepresentationInformation: pmc_8991834.pdf ReportingModule: PDF-hul, Rel. 1.12.1 (2019-04-17) LastModified: 2022-04-26 17:56:26 CEST Size: 3821643 Format: PDF Version: 1.4 Status: Well-Formed and valid SignatureMatches: PDF-hul MIMEtype: application/pdf PDFMetadata: Objects: 345 FreeObjects: 1 IncrementalUpdates: 0 DocumentCatalog: ViewerPreferences: HideToolbar: false HideMenubar: false HideWindowUI: false FitWindow: false CenterWindow: false DisplayDocTitle: false NonFullScreenPageMode: UseNone Direction: L2R ViewArea: CropBox ViewClip: CropBox PrintArea: CropBox PageClip: CropBox PageLayout: SinglePage PageMode: UseOutlines Language: en-US Outlines: Item: Title: Multimarker synaptic protein cerebrospinal fluid panels reflect TDP-43 pathology and cognitive performance in a pathological cohort of frontotemporal lobar degeneration Children: Item: Title: Abstract Children: Item: Title: Background: Item: Title: Methods: Item: Title: Result: Item: Title: Conclusion: Item: Title: Background Item: Title: Methods Children: Item: Title: Study design Item: Title: Neuropathological classification and quantification of neuropathological burden Item: Title: Statistical analysis Item: Title: Results Children: Item: Title: Demographics and clinical data Item: Title: Correlation between antemortem CSF levels of the synaptic proteins Item: Title: Antemortem CSF profile of the synaptic proteins across neuropathologic groups Item: Title: Association of antemortem CSF levels of the synaptic proteins with post-mortem pathological burden in FTLD Item: Title: Association of antemortem CSF levels of the synaptic proteins with cognitive performance in FTLD Item: Title: Discussion Children: Item: Title: Study limitations Item: Title: Conclusions Item: Title: Acknowledgements Item: Title: References Info: Title: Multimarker synaptic protein cerebrospinal fluid panels reflect TDP-43 pathology and cognitive performance in a pathological cohort of frontotemporal lobar degeneration Author: Alba Cervantes-González Subject: Molecular Neurodegeneration, https://doi.org/10.1186/s13024-022-00534-y Keywords: Calsyntenin-1;Frontotemporal lobar degeneration;Frontotemporal dementia;Cerebrospinal fluid;Biomarker;TDP-43;Tau Creator: Adobe InDesign 15.0 (Windows) Producer: Adobe PDF Library 15.0; modified using iText® 5.3.5 ©2000-2012 1T3XT BVBA (SPRINGER SBM; licensed version) CreationDate: Mon Apr 04 15:22:39 CEST 2022 ModDate: Fri Apr 08 12:56:56 CEST 2022 ID: 0xb248dc3cd5bf8e2202fe4ba0c73ff628, 0x910921586d55c8b5d8ccc0bd63b09111 Filters: FilterPipeline: FlateDecode Images: Image: NisoImageMetadata: FormatName: image/png ImageWidth: 39 ImageHeight: 39 BitsPerSample: 8 BitsPerSampleUnit: integer Filter: FlateDecode Intent: RelativeColorimetric Decode: 0, 255 Name: X Image: NisoImageMetadata: FormatName: image/png ImageWidth: 39 ImageHeight: 74 BitsPerSample: 8 BitsPerSampleUnit: integer Filter: FlateDecode Intent: 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panels reflect TDP-43 pathology and cognitive performance in a pathological cohort of frontotemporal lobar degeneration Alba Cervantes-González David J. 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