28bb5b24a39b97dfc4ab150692d21f48 pmc_9065415.pdf 8ca2896d01e13d7bd116ed8cf25ee7239aedab6e pmc_9065415.pdf fdbbdd5090d66ce636a61f90af8917d716dbd316a5fc600c25277c3cf1f83572 pmc_9065415.pdf Title: Elevated α-Ketoglutaric Acid Concentrations and a Lipid-Balanced Signature Are the Key Factors in Long-Term HIV Control Subject: Long-term elite controllers (LTECs) are a fascinating small subset of HIV individuals with viral and immunological HIV control in the long term that have been designated as models of an HIV functional cure Keywords: metabolomics, lipidomics, elite controllers (ECs), HIV infection, Kreb's cycle, long-term, viral, mass spectrometry Author: Jenifer Masip Creator: Arbortext Advanced Print Publisher 10.0.1306/W Unicode Producer: Acrobat Distiller 7.0 (Windows) CreationDate: Wed Apr 13 08:47:28 2022 CEST ModDate: Wed Apr 13 08:51:14 2022 CEST Custom Metadata: no Metadata Stream: yes Tagged: no UserProperties: no Suspects: no Form: none JavaScript: no Pages: 11 Encrypted: no 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s2_3 Item: Title: Determination of the Metabolomics Profile (Analytical Method) Destination: s2_4 Item: Title: Determination of the Lipidomics Profile (Analytical Method) Destination: s2_5 Item: Title: Statistical Analysis Destination: s2_6 Item: Title: Results Destination: s3 Children: Item: Title: Characteristics of the Study Participants Destination: s3_1 Item: Title: Tricarboxylic Acid Cycle Metabolites Were Increased in the Long-Term Elite Controller-Extreme Group Compared to the No-Long-Term Elite Controller Group Destination: s3_2 Item: Title: The Important Role of Lipid Species in Continuous Viral and Immunological HIV Control in Long-Term Elite Controllers Destination: s3_3 Item: Title: Metabolomics/Lipidomics Signatures Related to Long-Term Elite Controller-Extreme Could Be Potential Biomarkers of Long-Term Elite Controller Progression Destination: s3_4 Item: Title: Discussion Destination: s4 Item: Title: Data Availability Statement Destination: s5 Item: Title: Ethics Statement Destination: s6 Item: Title: Author Contributions Destination: s7 Item: Title: Funding Destination: s8 Item: Title: Acknowledgments Destination: bmark_-366698314 Item: Title: Supplementary Material Destination: bmark_386646472 Item: Title: References Destination: bmark_2090415954 Info: Title: Elevated α-Ketoglutaric Acid Concentrations and a Lipid-Balanced Signature Are the Key Factors in Long-Term HIV Control Author: Jenifer Masip Subject: Long-term elite controllers (LTECs) are a fascinating small subset of HIV individuals with viral and immunological HIV control in the long term that have been designated as models of an HIV functional cure Keywords: metabolomics, lipidomics, elite controllers (ECs), HIV infection, Kreb's cycle, long-term, viral, mass spectrometry Creator: Arbortext Advanced Print Publisher 10.0.1306/W Unicode Producer: Acrobat Distiller 7.0 (Windows) CreationDate: Wed Apr 13 08:47:28 CEST 2022 ModDate: Wed Apr 13 08:51:14 CEST 2022 ID: 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Benito Consuelo Viladés Graciano Garc&iacute a-Pardo José Alcam&iacute Ezequiel Ruiz-Mateos Frederic G&oacute mez-Bertomeu Montserrat Vargas Marta Navarro José A. Oteo Juan A. Pineda Anna Mart&iacute Ver&oacute nica Alba Francesc Vidal Joaquin Peraire Anna RullECRIS integrated in the Spanish AIDS Research Network metabolomics lipidomics elite controllers (ECs) HIV infection Kreb's cycle long-term viral mass spectrometry uuid:6d177482-246b-4e1f-8359-98c37d34e21a uuid:be3aac12-967a-455d-93aa-f6a62a1d8e3d Pages: Page: Label: 1 Annotations: Annotation: Subtype: Link Rect: 175, 592, 461, 613 Annotation: Subtype: Link Rect: 175, 569, 452, 590 Annotation: Subtype: Link Rect: 175, 546, 492, 567 Annotation: Subtype: Link Rect: 175, 523, 512, 544 Annotation: Subtype: Link Rect: 45, 29, 116, 36 Annotation: Subtype: Link Rect: 125, 29, 183, 36 Annotation: Subtype: Link Rect: 426, 29, 549, 36 Annotation: Subtype: Link Rect: 87, 488, 158, 496 Annotation: Subtype: Link Rect: 87, 359, 158, 366 Annotation: Subtype: Link Rect: 104, 339, 158, 346 Annotation: Subtype: Link Rect: 57, 64, 158, 71 Annotation: Subtype: Link Rect: 475, 736, 549, 743 Annotation: Subtype: Link Rect: 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